... polarization and organelle organization through the cytoskeleton, thereby controlling steroid production and secretion [28,30,34], but the possible role of integrin-mediated cytoskeleton changes has not ... caution owing to its overall actions on cell metabolism and ion membrane exchanges. Moreover, experiments with cytochalasin have not allowed the specific role of LN-induced cytoskeleton changes on ... cytoskeleton disruption by cytochalasin D on GC cultured on LN substratum To assess whether all or part of these functional changes might be the consequence of cell rounding, the action of cytochalasin...
Ngày tải lên: 05/03/2014, 17:20
... 9A and B, equimolar addition of G4–6 to actin at pH 5.7 produces only a small inhibition of the polymeriza- tion process when compared with the control condition (monitored at pH 7.5). These results ... in the presence of 5 m M EGTA to increase pH to a value of 6.25. (A) Log of fluorescence intensities corresponding to tryptophan emission (j) or Oregon green emission (h) is plotted vs. pH. (B) ... interaction was monitored at 405 nm. Ó FEBS 2003 Low pH activation of gelsolin (Eur. J. Biochem. 270) 4107 The activation of gelsolin by low pH The calcium latch is sensitive to calcium but not pH Emeline...
Ngày tải lên: 23/03/2014, 21:20
báo cáo hóa học:" Reduced renal function is associated with progression to AIDS but not with overall mortality in HIV-infected kenyan adults not initially requiring combination antiretroviral therapy" potx
... RJ, Perrone RD, Lau J, Eknoyan G: National Kidney Foundation practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Ann Intern Med 2003, 139:137-147. 14. Stohr ... function is associated with progression to AIDS but not with overall mortality in HIV-infected kenyan adults not initially requiring combination antiretroviral therapy. Journal of the International ... analyses. Conclusions: In this large natural history study, reduced renal function was strongly associated with faster HIV disease progression in adult Kenyans not initially meeting cART initiation criteria....
Ngày tải lên: 20/06/2014, 08:20
Báo cáo y học: " Hyperresponsiveness to inhaled but not intravenous methacholine during acute respiratory syncytial virus infection in mice" pot
Ngày tải lên: 12/08/2014, 18:20
Car Test -- Hydrogen On Demand (Pure hydrogen, not HHO) Can pure hydrogen (H2) replace HHO to increase MPG? pdf
... production). This is because our invention uses a process that only needs external heat to start the reaction, usually in the temperature range of 150F to 190F. Once started, the reaction, because ... enough heat to sustain the reaction. The only external energy required is for cooling, if needed to limit the production rate to some desired target value. Hydrogen production rates: Up to 4 LPM ... cells in non-laboratory (industrial) conditions because the scale-up of the present invention has no known Page 32 Phillips Company CT.p65 This is only a prototype system, intended to obtain...
Ngày tải lên: 07/03/2014, 11:20
Báo cáo y học: "Genetic polymorphism of p53, but not GSTP1, is association with susceptibility to esophageal cancer risk – A Meta-Analysis"
... gene-gene and gene-environment interactions are warranted to confirm the real contribution of these polymorphisms to esophageal cancer susceptibility. Conflict of Interest None declared. References ... including smoking or another environment factors will be helpful to con- firm the findings. Although there have been consistent findings that the p53 codon 72 Pro/Pro genotype was asso- ciated ... Causes Control 2004;15:1077-1083. 33 Murphy SJ, Hughes AE, Patterson CC, Anderson LA, Watson RG, Johnston BT, Comber H, McGuigan J, Reynolds JV, Murray LJ: A population-based association study...
Ngày tải lên: 25/10/2012, 11:40
Tài liệu Báo cáo khoa học: Activated Rac1, but not the tumorigenic variant Rac1b, is ubiquitinated on Lys 147 through a JNK-regulated process docx
... GTPases (Rho, Rac, Cdc42) control basic cellular functions, including actin cytoskeleton organization, vesicular trafficking, tran- scriptional regulation and cell cycle progression, and are therefore ... polyubiquitination as compared to control Rac1L61 or to the Rac1L61R96 ‘ubiquitina- tion-irrelevant’ lysine mutant (Fig. 2A, top panel). Consistent with inhibition of their polyubiquitination, both ... normalized to total Rac expression relative to the control in the untreated condition, considered as 100%. The data are representative of two independent experiments. O. Visvikis et al. Ubiquitination...
Ngày tải lên: 18/02/2014, 16:20
look at the important information in this header.1look at the important information in this header.We encourage you to keep this file on your own disk, keeping an electronic path open for the next readers. Do not remove this. **Welcome To The World o doc
... woman belonging to the people, a woman who could not resign herself to growing old. If only Sophie-Victoire had been of a tranquil disposition! She was most restless, on the contrary, wanting to change ... position and your health allow you to do, provided that you do not compromise the honour or the reputation of any one else. I do not see that a young man is called upon to be as chaste as a nun. But ... Clouard, Dr. Cabanes, Monsieur Marieton, the enthusiastic collector, Spoelberch de Lovenjoul and Monsieur Decori have all given us their contributions to the debate.[19] Thanks to them, we have the...
Ngày tải lên: 06/03/2014, 23:21
Báo cáo khoa học: Protein crystallography for non-crystallographers, or how to get the best (but not more) from published macromolecular structures potx
... contribution to X-ray scattering is correctly taken into account. Some refinement programs have options for such a treatment of hydrogen atoms in an automatic way. At high resolution their contribution may ... contribution may result in a drop of the overall R-factor by a few percent. Moreover, if H atoms are not included, their contribution is represented completely by the parent atom and its position ... their use, but only to provide some guidance as to their meaning. R-factor and R free As mentioned earlier, residuals, or R-factors, usually expressed as percent, but often as decimal fractions, measure...
Ngày tải lên: 16/03/2014, 06:20
Kogan Page - Business Solutions on Demand - Transform the Business to Deliver Real Customer Value docx
... of its customers. With contributions from a host of why corporations need to provide business solutions to stay competitive; why business customers want to buy solutions; what it takes to move ... solution creation and delivery. Sony’s strategic vision Sony has a vision of a future in which electronics, telecommunications and information technologies are converging. It anticipates that customers ... approaches, Sony will capitalize on its unique combination of hardware and content assets. [20 ] Nobuyuki Idei, Sony chairman and CEO, commented: Sony will continue to focus on and consolidate...
Ngày tải lên: 22/03/2014, 14:20
báo cáo hóa học: " Boosting with intranasal dendrimeric Aβ1–15 but not Aβ1–15 peptide leads to an effective immune response following a single injection of Aβ1–40/42 in APP-tg mice" ppt
... not reach significance. Conclusion: Our results demonstrate that priming with full length Aβ40/42 followed by boosting with dAβ1–15 but not Aβ1–15 peptide led to a robust humoral immune response ... article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0 ), which permits unrestricted use, distribution, and reproduction in any ... epitope in humans [15], monkeys [16] and mice [17-19] is located in the Aβ1–15 region, whereas the T cell epitope has been mapped to within Aβ15–42 [20,21]. Based on these non- overlapping epitopes,...
Ngày tải lên: 19/06/2014, 22:20
Báo cáo y học: " HIV-1 reverse transcriptase mutations that confer decreased in vitro susceptibility to anti-RT DNA aptamer RT1t49 confer cross resistance to other anti-RT aptamers but not to standard RT inhibitors" docx
... HIV-1 RT shown to confer resistance to AZT (T215Y/M41L) and ddI and ddC (L74V) were sensitive to inhibition by RT1t49 (Table 3). In contrast, mutations shown to confer resistance to mul- tiple ... mutation conferred a greater degree of resistance compared to the N255D mutation. In addition, the presence of both mutations led to an even greater degree of resistance (6- to 27-fold) to aptamers ... resistance to RT1t49 (3 to 5-fold). On the one hand, these results suggest that pre-existing NRTI-resistance mutations, due to altered affinities to template·primer can confer co- resistance to aptamers...
Ngày tải lên: 10/08/2014, 05:20
Báo cáo y học: "CCR5 signalling, but not DARC or D6 regulatory, chemokine receptors are targeted by herpesvirus U83A chemokine which delays receptor internalisation via diversion to a caveolin-linked pathway" pdf
... chemokine receptor in model system to compare to regulatory receptors In order to investigate U83A activities on regulatory recep- tors and to compare them to those on signalling receptors, U83A ... to infection. For HIV-1 it not only serves as co- receptor, but activation via CCR5 is important in develop- ment of an efficient immune response to the infection [45,46]. CCR5 is expressed on ... chemokine concentrations. Biochem Biophys Res Com- mun 2003, 303:137-9. 34. Gardner L, Wilson C, Patterson AM, Bresnihan B, FitzGerald O, Stone MA, Ashton BA, Middleton J: Temporal expression pattern of...
Ngày tải lên: 11/08/2014, 08:22
Báo cáo y học: " Recovery from depressive symptoms, state anxiety and post-traumatic stress disorder in women exposed to physical and psychological, but not to psychological intimate partner violence alone: A longitudinal study" doc
... symptoms. On the contrary, a high intake of psy- chotropic drugs predicted the continuation of the three disorders, and a high perception of lifetime events con- tributed to the continuation of ... a cessation or reduction of IPV over time, women exposed to psy- chological IPV alone have a high probab ility of contin- ued exposure to the same type of IPV. Factors contributing to these differences ... possible. Variables contributing to the recovery of mental health To determine the variables that contributed to the recovery from depression, anxiety and PTSD symptoma- tology for the physically/psychologically...
Ngày tải lên: 11/08/2014, 16:22
báo cáo khoa học: " Sgt1, but not Rar1, is essential for the RB-mediated broad-spectrum resistance to potato late blight" pptx
Ngày tải lên: 12/08/2014, 05:20