skin diseases of general importance part ii

... (with name and office seal) Signature of Cashier (with name and office seal) Supervisor/Incharge of Deposit office alongwith office seal Supervisor/Incharge of Deposit office alongwith office seal ... Postmaster/Incharge of Transferer office) of Transferer office) Date……………………….…& office Seal Date……………………………& office Seal (Countersigned Postmaster/Incharge of Transferer office) Date…………………… …& office Seal ... favour of the deposit office, or in favour of the deposit office (2) Where a deposit is made by cheque or demand draft, the date of deposit under these rules shall be the date of encashment of the...

Ngày tải lên: 29/03/2014, 09:20

... registration number of the company (b) (a) *Name of the company *Address of the registered office or of the principal place of business in India of the company (c) Global location number (GLN) of company ... sub-section (6) of section 209 of the Act, shall be punishable as provided under sub-section (2) of section 642 read with sub-sections (5) and (7) of section 209 of Companies Act, 1956 (1 of 1956) Savings- ... under Rule of the Companies (Cost Accounting Records) Rules, 2011 of … (mention name of the company) having its registered office at (mention registered office address of the company)...

Ngày tải lên: 29/03/2014, 14:20

... versed in the recognition of cutaneous lesions or their spectrum of presentations Therefore, the authors of this chapter have decided to cover this particular topic of cutaneous medicine not ... parapsoriasis and is suggested by an increase in the thickness of the lesions The diagnosis of CTCL is established by skin biopsy in which collections of atypical T lymphocytes are found in the epidermis ... arsenic c See also Red Lesions in "Papulonodular Skin Lesions." d See also Red-Brown Lesions in "Papulonodular Skin Lesions." Whenever the diagnosis of pityriasis rosea or lichen planus is made,...

Ngày tải lên: 06/07/2014, 20:20

... is also important to examine the skin carefully for a migration of the erythema and associated secondary changes such as pustules or erosions Migratory waves of erythema studded with superficial ... Gener alized, Wax- but like Skin biopsy Isotre tinoin or perifollicular characteristic keratoderma acitretin; papules "skip" methotrexate areas Excl of normal ude skin cutaneous T cell lymphoma ... Locati Othe Diag Treat on of Initial r Findings nostic Aids ment Lesions Psori asisa Pink- Elbow red, silvery s, scale, sharply scalp, demarcated Nail knees, dystrophy, biopsy Skin Topic al arthritis,...

Ngày tải lên: 06/07/2014, 20:20

... up to 25% of the cases of erythroderma were due to CTCL The patient may progress from isolated plaques and tumors, but more commonly the erythroderma is present throughout the course of the disease ... cases of erythroderma where there is no apparent cause (idiopathic), longitudinal follow-up is mandatory to monitor for the possible development of CTCL There have been isolated case reports of ... late stage of the disease Alopecia (Table 54-4) The two major forms of alopecia are scarring and nonscarring In scarring alopecia there are associated fibrosis, inflammation, and loss of hair follicles...

Ngày tải lên: 06/07/2014, 20:20

... sensitivity If no evidence of of hyperandrogen pattern; female midline of the scalp affected hairs to state, pattern) the effects then topical of minoxidil; Recession of finasteridea; testosterone ... coalescence of associated lesions and/or diseases: involvement of other hyperthyroidism, hair-bearing surfaces hypothyroidism, contact of the body vitiligo, Down syndrome Pitting of the nails ... Increased levels of circulating androgens (ovarian or adrenal source in women) Alopecia areata Well- The circumscribed, Topical germinative zones anthralin; circular areas of hair of the hair follicles...

Ngày tải lên: 06/07/2014, 20:20

... 54-6 Causes of Figurate Skin Lesions I Primary cutaneous disorders A Tinea B Urticaria (≥90% of cases) C Erythema annulare centrifugum D Granuloma annulare E Psoriasis II Systemic diseases A Migratory ... the scarring lesions of discoid lupus can be seen in patients with systemic lupus, in the majority of cases the disease process is limited to the skin Less common causes of scarring alopecia ... areas of previous inflammation are often hypopigmented with a rim of hyperpigmentation In lichen planus the peripheral perifollicular macules are usually violet-colored Complete examination of...

Ngày tải lên: 06/07/2014, 20:20

... syndrome have episodes of flushing of the head, neck, and sometimes the trunk Resultant skin changes of the face, in particular telangiectasias, may mimic the clinical appearance of acne rosacea Pustular ... cutaneous disorders A Acne vulgaris B Acne rosacea II Drugs, e.g., anabolic steroids, glucocorticoids, lithium, iodides, EGFR a inhibitors III Systemic diseases A Increased androgen production Adrenal ... acne rosacea, the two major forms of acne (Chap 53), there are drugs and systemic diseases that can lead to acneiform eruptions (Table 54-7) Table 54-7 Causes of Acneiform Eruptions I Primary...

Ngày tải lên: 06/07/2014, 20:20

... Table 54-8 Causes of Telangiectasias I Primary cutaneous disorders A Linear Acne rosacea Actinically damaged skin Venous hypertension Essential telangiectasia ... Ionizing radiationa Poikiloderma vasculare atrophicans C Spider angioma Idiopathic Pregnancy II Systemic diseases A Linear Carcinoid Ataxia-telangiectasia Mastocytosis B Poikiloderma Dermatomyositis...

Ngày tải lên: 06/07/2014, 20:20

... the P gene (type II) ; patients with type IA OCA have a total lack of enzyme activity At birth, different forms of OCA can appear similar—white hair, gray-blue eyes, and pink-white skin However, ... decreased activity will acquire some pigmentation of the eyes, hair, and skin as they age The degree of pigment formation is also a function of racial background, and the pigmentary dilution ... pathognomonic signs of the three major autoimmune connective tissue diseases lupus erythematosus, scleroderma, and DM They are easily visualized by the naked eye and occur in at least two-thirds of these...

Ngày tải lên: 06/07/2014, 20:20

... syndromes (types I and II) Diseases of the thyroid gland are the most frequently associated disorders, occurring in up to 30% of patients with vitiligo Circulating autoantibodies are often found, and ... perifollicular macules of normal pigmentation are seen within areas of depigmentation The basis of this leukoderma is unknown; there is no evidence of inflammation in areas of involvement, but it ... diameter Non reflection of aging; UV Shins exposure and extensor forearms Postinfla mmatory Can develop Depe nds Type on of Block Trea in transfer of t hypopigmentati within active particular inflammatory...

Ngày tải lên: 06/07/2014, 20:20

... the result of the migration of two clones of primordial melanocytes, each with a different pigment potential Localized areas of decreased pigmentation are commonly seen as a result of cutaneous ... been observed in the skin overlying active lesions of sarcoidosis (see "Papulonodular Skin Lesions," below) as well as in CTCL Cutaneous infections also present as disorders of hypopigmentation, ... setting they are a sign of systemic disease, and that setting is the sudden appearance of multiple lesions, often with an inflammatory base and in association with acrochordons (skin tags) and acanthosis...

Ngày tải lên: 06/07/2014, 20:20

... location as circular areas of erythema that can become bullous and then resolve as brown macules The eruption usually appears within hours of administration of the offending agent, and common ... 80–90% of adult patients with type I NF will have six or more CALM measuring ≥ 1.5 cm in diameter Additional findings are discussed in the section on neurofibromas (see "Papulonodular Skin Lesions," ... leukoplakia of the oral and anal mucosae The latter often develops into squamous cell carcinoma In addition to the flagellate pigmentation (linear streaks) on the trunk, patients receiving bleomycin often...

Ngày tải lên: 06/07/2014, 20:20

... "Vesicles/Bullae," below), the skin darkening is seen in sun-exposed areas and is a reflection of the photoreactive properties of porphyrins The increased level of iron in the skin of patients with hemochromatosis ... deposits of a particular drug or metal in the skin are seen with silver (argyria), where the skin appears blue-gray in color; gold (chrysiasis), where the skin has a brown to blue-gray color; and clofazimine, ... widespread deposition of melanin resulting from the high concentration of circulating melanin precursors, there is more evidence to support the latter Of the autoimmune diseases associated with...

Ngày tải lên: 06/07/2014, 20:20

... Enteroviruses, e.g., hand-foot-and-mouth disease Staphylococcal scalded -skin syndromea,f Bullous impetigoa II Systemic diseases A Autoimmune Paraneoplastic pemphigusa B Infections Cutaneous embolib ... herpetiformisb,c Linear IgA bullous dermatosisb Epidermolysis bullosa acquisitab,d B Secondary blistering diseases Contact dermatitisa Erythema multiformea,b Stevens-Johnson syndrome Toxic epidermal necrolysisb ... Diabetic bullaea,b Porphyria cutanea tardab Porphyria variegatab Pseudoporphyriab Bullous dermatosis of hemodialysisb D Ischemia Coma bullae a Intraepidermal b Subepidermal c Associated with gluten...

Ngày tải lên: 06/07/2014, 20:20

... slough This results in large areas of denuded skin The associated morbidity, such as sepsis, and mortality are relatively high and are a function of the extent of epidermal necrosis In addition, ... centers of which may become vesicular The clue to the diagnosis of EM, as opposed to a morbilliform exanthem, is the development of a "dusky" violet color or petechiae in the center of the lesions ... diagnosis of SSSS versus TEN can be made by a frozen section of the blister roof or exfoliative cytology of the blister contents In SSSS the site of staphylococcal infection is usually extracutaneous...

Ngày tải lên: 06/07/2014, 20:20

... infection, and hepatomas The differential diagnosis of PCT includes (1) porphyria variegata—the skin signs of PCT plus the systemic findings of acute intermittent porphyria; it has a diagnostic ... can include hypertrichosis of the lateral malar region (men) or face (women) and, in sun-exposed areas, hyperpigmentation and firm sclerotic plaques An elevated level of urinary uroporphyrins confirms ... disease)—erythema of the cheeks is followed by a reticulated pattern on extremities; it is secondary to a parvovirus B19 infection, and an associated arthritis is seen in adults Table 54-13 Causes of Exanthems...

Ngày tải lên: 06/07/2014, 20:20

... (Chap 129), and three of these involve mucocutaneous sites (diffuse erythema of the skin, desquamation of the palms and soles 1–2 weeks after onset of illness, and involvement of the mucous membranes) ... petechiae of the palate; a facial flush with circumoral pallor; linear petechiae in the antecubital fossae; and desquamation of the involved skin, palms, and soles 5–20 days after onset of the eruption ... the majority of cases were reported in menstruating women who were using tampons However, other sites of infection, including wounds and vaginitis, can lead to TSS The diagnosis of TSS is based...

Ngày tải lên: 06/07/2014, 20:20

... pressure or scratching of the skin It is a common disorder, affecting ~5% of the population Solar urticaria characteristically occurs within minutes of sun exposure and is a skin sign of one systemic ... associated with wheezing Whereas urticarias are the result of dermal edema, subcutaneous edema leads to the clinical picture of angioedema Sites of involvement include the eyelids, lips, tongue, larynx, ... resolved The patient may also complain of burning rather than pruritus On biopsy, there is a leukocytoclastic vasculitis of the small blood vessels Although many cases of urticarial vasculitis are idiopathic...

Ngày tải lên: 06/07/2014, 20:20

... II Skin- colored A Rheumatoid nodules B Neurofibromas (von Recklinghausen's disease) C Angiofibromas (tuberous sclerosis, MEN syndrome, type 1) ... leukocytoclastic vasculitis) E Lupus vulgaris VII Bluea A Venous malformations (blue rubber bleb syndrome) B Primary cutaneous disorders Venous lake Blue nevus VIII Violaceous A Lupus pernio (sarcoidosis) ... disease) F Osteomas (Gardner syndrome) G Primary cutaneous disorders Epidermal inclusion cysts Lipomas III Pink/translucenta A Amyloidosis B Papular mucinosis IV Yellow A Xanthomas B Tophi C Necrobiosis...

Ngày tải lên: 06/07/2014, 20:20