... Crystal structure of botulinum neurotoxin type A and implications for toxicity. Nat Struct Biol 5, 898–902. Engineering toxins for 21st century therapies J. A. Chaddock and K. R. Acharya 904 FEBS Journal ... translocation, whereas BoNT ⁄ A required apHof 5 for efficient LC translocation. Montal J. A. Chaddock and K. R. Acharya Engineering toxins for 21st century therapies FEBS Journal 278 (2011) 899904 ... that lead to cell death. The most prevalent target for such novel molecules has been for the treatment of cancer and proliferative diseases. For example, the literature is rich with exam- ples...
Ngày tải lên: 28/03/2014, 23:20
Ngày tải lên: 10/08/2014, 09:20
Farm Business Management for the 21st Century: Checking Your Farm Business Management Skills pot
... Lafayette, IN 47907 Farm Business Management for the 21 st Century Checking Your Farm Business Management Skills 2 Checking Your Farm Business Management Skills ã ID-237 Purdue Extension ã ... attitudes and skills as well. The assessment checklists included identify those attitudes and skills in four fundamental areas: Production and operations management skills, Financial management skills, General ... publications providing information and strategies for coping and managing in times of financial stress <http://www.agriculture.purdue.edu/agtransition/family.html>. For additional information and...
Ngày tải lên: 29/03/2014, 18:20
Cambridge.University.Press.Neuroethics.Challenges.for.the.21st.Century.Aug.2007.pdf
... even earlier ancestors? If souls are necessary for intelligent behavior – for tool use, for communica- tion, for complex social systems, or even for morality (or perhaps, better, proto-morality) ... or in depression, for instance – then we can hope to treat it with means much less dramatic than surgery. BIID is therefore at once a question for the sciences of the mind and for ethics; it is ... cognitively expensive: we use it to form an internal representation only when it seems necessary. For most purposes, most of the time, we save our cognitive resources by forming only the sketchiest of...
Ngày tải lên: 21/09/2012, 10:58
Media Education for the 21st Century
... students Today’s Challenges for Media Education Technorati (“the google of blogs”) 4. The Ability to Manage Media : The ability to collaborate, to be flexible in adapting to new forms and to effectively ... sources of communication (mobile phones, internet) are a factor Hanoi University (formerly Hanoi University of Foreign Studies) The first university in Vietnam (2002) to offer courses in English ... Ability to Make Media: The ability to create media work across written, video, audio, and internet formats Thực hiện: Có thể làm một công việc về truyền thông bằng các hình thức nghe, nhìn, viết...
Ngày tải lên: 19/01/2013, 09:55
Introduction of Neuroethics Challenges for the 21st Century
... even earlier ancestors? If souls are necessary for intelligent behavior – for tool use, for communica- tion, for complex social systems, or even for morality (or perhaps, better, proto-morality) ... or in depression, for instance – then we can hope to treat it with means much less dramatic than surgery. BIID is therefore at once a question for the sciences of the mind and for ethics; it is ... but by forging coalitions between the disparate elements of ourselves. These coalitions remain forever vulnerable to disruption, short and long term. One way to understand drug addiction, for instance,...
Ngày tải lên: 01/11/2013, 09:20
Tài liệu Engineering Challenges For the 21st Century ppt
... ã BrainDrain Developedcountriescanalwaysrecruit professionalengineersandtechnologists fromdevelopingcountries Developingcountriessufferonthreecounts: First,theydonotproduceenoughengineersfortheir ownrequirement Secondly,theyexpendscarcehardforeigncurrencyin sendingtheirstudentsforexpensiveengineeringcourses indevelopedcountries. Thirdly,theconstantdrainofengineers,usuallythebest andthebrightest,tothedevelopedcountries. ... ã theFutureofEngineeringandtheFortune ofEngineerslieinsmallandmediumscale enterprises(SME)thatareengagedin engineeringinnovations ThisParadigmShiftwillmostlyoccurinSME withtheYounginchargeastheyarewithoutthe traditionalbaggageofcautionandconservatism oftheengineeringprofession. ã InDevelopingCountries MoreInfrastructureDevelopmentneeded forhousing,educationalandhealthcare facilities. Moreroads,portsandairportswillbe requiredtoenablefood,produceand productsaccesstodomesticandoverseas markets. Energyandwatersupplyneedtobemade availabletoremoteareas. ICTnetworksshouldcoverallpartsofthe country. ... ã Therequisiteintellectualcapitalisnot universallyavailable,butitisfarmore widespreadinthedevelopingworldthan financecapital. UtilizingICTorbridgingtheDigitalDivide isaprerequisitefortransitionto sustainability. ã ExtendingMobilityWorldwidewould requireInter-Government-Professional PrivateSectorPartnership: UNESCO/WFEOforAccreditationof EngineeringCourses WTO/WFEOforMobilityofEngineers ...
Ngày tải lên: 26/01/2014, 02:20
Tài liệu Preparing the Western Cape for the Knowledge Economy of the 21st Century ppt
... Preparing the Western Cape for the Knowledge Economy of the 21st Century Preparing the Western Cape for the Knowledge Economy of the 21st Century White Paper ... safer environment for all our people; ã To create an enabling environment for economic growth; ã To prepare the people of the province for the knowledge economy of the 21st century; ã To contain ... Cape for the Knowledge Economy of the 21st Century White Paper Department of Economic Affairs, Agriculture & Tourism 10 World Bank Development Report, Entering the 21st Century...
Ngày tải lên: 27/01/2014, 12:20
The Public Health Workforce: An Agenda for the 21st Century ppt
... communities in the 21st century. The Public Health Workforce: An Agenda For The 21st Century 16 DISTANCE LEARNING All partners in the effort to strengthen the public health workforce should make ... Public Health Workforce: An Agenda For The 21st Century 28 Descriptions of Selected Public Health Workforce Assessment Studies Investigator(s) Study Objectives Methods Type of Information The George ... the References. The Public Health Workforce: An Agenda For The 21st Century 30 ã Design and operate a surveillance system ã Understand analytic skills for survey development and administration ã...
Ngày tải lên: 05/03/2014, 21:20
21st Century Welfare: Presented to Parliament by the Secretary of State for Work and Pensions by Command of Her Majesty pptx
... can be accessed online at: www.dwp.gov.uk /21st- century- welfare For more information about this publication, contact: Benefit Reform Division Department for Work and Pensions 1st Floor Caxton ... 5 Delivery of a reformed system 5 Delivery of a reformed system. Summary A 21 st century welfare system requires a 21 st century delivery solution. More work would be needed to decide the ... Fiscal Studies. 18 Chapter 3 Principles and options for reform Principles for reform 1. We would propose to use a set of principles to guide reform. They could be to: ã ensurethatpeoplecanseethattheclearrewardsfromtakingalltypes...
Ngày tải lên: 06/03/2014, 08:20
Community Mental Health Challenges for the 21st Century pdf
... Life skills groups focus on educational training and the development of volunteer and social roles. Skills training can enhance the “I can” attitude, which is essential for individual trans - formation. ... are used only for identification and explanation without intent to infringe. Library of Congress Cataloging-in-Publication Data Community mental health : challenges for the 21st century / [edited ... consciousness, which precedes individ- ual transformation or social change (Freire, 2000). The goal is therefore not that the client be a repository for the worker’s plans, but rather an essential...
Ngày tải lên: 15/03/2014, 01:20
10 Quick Tips for Small Businesses in the 21st Century pdf
... time to ask them for their thoughts - people tend to be receptive when asked for their opinion! Business is just common sense I’m not for a moment saying that business is easy. For most of us ... searches for keywords and phrases. This can help give you an idea of 1) how many people are actively searching for your product or service and 2) what the most popular keyword phrases are for your ... business strategy in the digital age. In the middle of 2012 I setup the 21st Century SME blog to share these ideas. Both before and during this period I also created and ran my own SMEs, which...
Ngày tải lên: 17/03/2014, 16:20
Essays on Aesthetic Education for the 21st Century - Tracie Costantino and Boyd White (Eds.) pdf
... three ways”: We perform an action on something; it performs one on us; or thirdly, the two actions “blend”, thus forming a reciprocal action. It is the reciprocity of this third form that Siegesmund ... discussion of poetic form, which White uses as a springboard for his applied discussion of the relationship between form and content in the realm of beauty and value in visual images. For his examples, ... terms “positive forms of otherness.” In her conclusion, Illeris further outlines this promising framework for facilitating transformative relationships with contemporary art for young people....
Ngày tải lên: 23/03/2014, 11:20
DESIGNING GRAPHIC DESIGN HISTORY: TEACHING FOR THE 21ST CENTURY CLASSROOM potx
... collections and archives to digital formats, spreading an unlimited wealth of data and information not previously accessible to the general public. As more information is placed in the public ... only the twentieth century. Print vs. Web Design While brainstorming how the interface for GDHit would look and function, it became clear to this designer how designing for the screen is ... The home page displays links to “Find Out More,” “Enter the Timeline” and “Sign up for Email Updates.” “Sign up for Email Updates,” allows the user to follow the development of the timeline, similar...
Ngày tải lên: 23/03/2014, 22:20
Programming in Go: Creating Applications for the 21st Century, Rough Cuts docx
... Floating-point numbers in Go are held in the widely used IEEE-754 format ( http://en.wiki- pedia.org/wiki/IEEE_754-2008 ). This format is also the native format used by many microprocessorsand floating-point ... need to perform arithmetic or comparisons on typed numbers of different types we must perform conversions—usually to the biggest type to avoid loss of accuracy. Conversions take the form type(value) and ... of byte as a synonym for the unsigned uint8 type, and encourages the use of rune as a synonym for the int32 type when working with individual characters (i.e., Unicode code points) .For most process- ing...
Ngày tải lên: 29/03/2014, 22:20
scientific american - 1995 09 - 150th anniversary issue - key technologies for the 21st century
Ngày tải lên: 12/05/2014, 15:02