Ngày tải lên: 23/03/2014, 01:20
... expressing CCR1, CCR2 or CCR5 mRNA within and around inflammatory foci in the spinal cord of rats with EAE, thus identifying potential determinants for trafficking of these cells to the CNS These findings ... immunization) of EAE show extensive inflammation involving the white and grey matter (D), with marked demyelination in the inflammatory areas (F) The majority of the infiltrating inflammatory cells are macrophages, ... rats in the acute phase (day 13) revealed marked inflammatory lesions in the white and grey matter of the spinal cord (Fig 3D) Within the inflammatory infiltrates, numerous actively phagocytosing...
Ngày tải lên: 19/06/2014, 22:20
Báo cáo sinh học: "Systemic 5-fluorouracil treatment causes a syndrome of delayed myelin destruction in the central nervous system" doc
... treatment, there was a 2.5-fold increase in apoptosis in the subventricular zone (SVZ) and a 4-fold increase in the dentate gyrus of the hippocampus (DG) The increased cell death persisted in the SVZ ... F4/80 staining was markedly increased at day in one of the ten mice treated with 5-FU (Figure 11a,b) In this animal, there was diffuse microglial activation throughout the brain, including the primary ... 5c,d) As >90% of the BrdU+ cells in the CC were Olig2+, these results indicate that the reduction in DNA synthesis observed in this tissue predominantly affected O-2A/OPCs [97,98,101] In contrast...
Ngày tải lên: 06/08/2014, 18:21
Báo cáo khoa học: "Immunohistochemical study of constitutive neuronal and inducible nitric oxide synthase in the central nervous system of goat with natural listeriosis" potx
... single positive-staining bacteria were found in the neuronal processes Both nNOS and iNOS immunoreactivity were found in a proportion of the neurons in the brainstem and the staining pattern was ... and iNOS in neurons increased when bacterial encephalitis occurred This is the first study of NOS expression in the goat brain with listeriosis The involvement of iNOS in bovine and caprine listeriosis ... observed in inflammatory microabscesses Counterstained with hematoxylin Magnification: ×132 C: Immunohistochemical staining of inducible NOS in the caprine brain with natural listeriosis shows that iNOS...
Ngày tải lên: 07/08/2014, 14:23
báo cáo khoa học: "In vivo observation of gold nanoparticles in the central nervous system of Blaberus discoidalis" potx
... nanoparticles will interact with the proteins present in the biological system, i.e the material surrounding the nanoparticles are proteins present in the nervous system of the cockroach Discussion The results ... by the nAuNPs The XPS was used to verify the presence of nAuNPs embedded in the brain tissue The confocal microscope and TEM were used to gain insights into the interaction of nAuNPs and the insect’s ... vibration in the building Although proteins not break into ions, introducing charged particles into the nervous system causes an imbalance in the signal transmission that links to the insect’s locomotion...
Ngày tải lên: 11/08/2014, 00:22
The role of hydrogen sulfide in the central nervous system implications in the treatment of alzheimers disease
... like tau is involved in microtubule assembly It serves as a binding for the tubulin Mutations in α-synuclein lead to loss of this binding ability, resulting in tubulin and α-synuclein aggregation ... enhancing the activity of gamma-glutamylcysteine synthetase and up-regulating cystine transport The upregulation in gammaglutamylcysteine synthetase activity facilitates the redistribution of GSH into ... pioneering study done by Zhang et al suggests that H2S could protect the brain against VD injury induced by cerebral ischemia reperfusion through inhibiting the apoptosis in the hippocampus They...
Ngày tải lên: 09/09/2015, 08:17
Chemical drug assisted gene transfer a sensible approach to improve transgene expression in the central nervous system
... μl of the complexes containing μg DNA was used in each injection The rate of injection was μl/min and the needle was allowed to remain in situ for mins before being slowly retracted at the end ... gene therapy by increasing the expression of the transgene In addition, with their intrinsic anti-tumor activities, HDAC inhibitors also have the advantage to kill tumor cells more effectively in ... remain at large in terms of choosing appropriate MW PEIs and biodegradable linkages as well as designing the degree of cross-linking, the particle size and the surface charge of the resulting...
Ngày tải lên: 12/09/2015, 10:15
A study of the recombination activating gene 1 in the zebrafish nervous system
... brief overview of the nervous system The nervous system is the most complex organ system in animals, and makes them distinguishable from other living organisms Because of the nervous system, animals ... substrate, X-gal The results from these studies were exciting Besides staining in the immune system, which was expected, X-gal staining was specifically detected in the brain and spinal cord among ... 5.1 Hypothesis about DNA recombination in the nervous system 138 5.1.1 Evidence for the presence of DNA rearrangement in the nervous system 138 v 5.1.2 Mutations in NHEJ pathway cause the increase...
Ngày tải lên: 15/09/2015, 17:09
Specificity and diversity in the vertebrate nervous system an analysis of two genes
... guidance at the midline, Eph-Ephrins are also involved in creating patterned neuronal connections in the CNS and the peripheral nervous system Similar to the topographic mapping in the visual system, ... target neurons in the tectum The Recombination activating gene-1 (RAG1) is expressed in the vertebrate immune system and in the nervous system, including the zebrafish visual system (Chun et ... Wilkinson, 16 1999) The role of Eph-Ephrin signaling is well studied in the visual system (discussed in first section), but they are also known to be involved in axon guidance elsewhere in the nervous...
Ngày tải lên: 16/09/2015, 08:31
INVESTIGATION OF MEMBRANE PROPERTIES IN THE CENTRAL NERVOUS SYSTEM OF DROSOPHILA MELANOGASTER STUDIED BY FLUORESCENCE CORRELATION SPECTROSCOPY
... constituent instead of sphingomyelin (PE-cer has phosphoethanolamine as the head group, instead of the phosphocholine head group in SM) [32] Despite having shorter fatty acyl chains (the longest being ... be studied using FCS These intensity fluctuations contain information which can be extracted by analysing the rates and the amplitudes of the intensity fluctuations and subjecting them to an autocorrelation ... tube The eppendorf tube was kept cold at °C in ice After collecting 10 larval brains, they were washed times with 200 µl of sterile-filtered HL3 containing 10 µg/ml of insulin The brains were then...
Ngày tải lên: 12/10/2015, 17:36
Báo cáo khoa hoc:" Peripheral nervous system manifestations in a Sandhoff disease mouse model: nerve conduction, myelin structure, lipid analysis" pot
... central nervous system (CNS) and elucidation of the peripheral nervous system (PNS) in patients and animal models remains incomplete To illuminate our understanding of SD as pertaining to the integrity ... plotted against the fourth power of the Bragg order (h4), the y-intercept of the trend-line is inversely proportional to the number of the repeating units (i.e., myelin membrane pairs) and the slope ... Unlike the CNS findings, no reduction of compact myelin was detected in the PNS In accordance with this finding, no change in the amount of cerebrosides or sulfatides was detected in the PNS...
Ngày tải lên: 11/08/2014, 08:21
Report Development Tools Building Custom Reports in the R/3 System
... Self-Defined OIW Information Catalog C–8 Activating the OIW Browser in Excel C–10 Downloading/Refreshing the OIW Information Catalog in Excel C–11 Defining and Fine-tuning ... to the SD DemoCube Channel 11–6 Viewing Data in the SAP DemoCube 11–7 Using the InfoCatalog .11–10 Accessing the InfoCatalog 11–10 From the BW Main Screen ... From the BW Administrator Workbench 11–11 Arranging Workbooks in the Enterprise InfoCatalog 11–12 Creating Directories in the Enterprise InfoCatalog 11–12 Getting the Most...
Ngày tải lên: 27/10/2013, 07:15
Tài liệu Addressing the Mental Health Needs of Young Children in the Child Welfare System pdf
... appropriate interactions, and guide the child and the mother in creating a joint narrative of the traumatic events while working toward their resolution The treatment manual includes clinical strategies ... social interaction The initial assessment sessions include individual sessions with the mother to communicate emerging assessment findings, agree on the course of treatment, and plan how to explain ... based on the “Strengthening Early Childhood Mental Health Supports in Child Welfare Systems” emerging issues roundtable convened by NCCP in New York City in June 2009 The meeting brought together...
Ngày tải lên: 12/02/2014, 19:20
Tài liệu Báo cáo khoa học: "Multimodal Generation in the COMIC Dialogue System" docx
... Because the fission module needs the timing information from the speech synthesiser to finalise the schedules for the other modalities, the synthesiser first prepares and stores the waveform for its input ... example, the input in Figure could equally well have been the user simply pointing to a design on the screen, with no speech at all This would have resulted in the same abstract DAM input, and thus in ... off of the stack as the dialogue proceeds When processing a user input, the control structure decides whether the DAM can stay within the current topic (and thus the current DAF), or whether a...
Ngày tải lên: 20/02/2014, 15:20
Tài liệu Báo cáo khoa học: "Subgrammars, Rule Classes and Control in the Rosetta Translation System" ppt
... of the basic expressions (basic meanings) the meaning of the rules (rule m e a n i n g s ) In Montague Grammar these meanings are expressed in intensional logic In the Rosetta system the meanings ... In many cases the grammar writer has a certain ordering of the rules in mind, e.g he may want to express that the rules for inserting determiners during NP-formation should be applied after the ... and C L A U S E ) The fact that in X-theory the phrase markers of the resulting constituents are In the example of the smart girl / the girl that is 8mart the subgrammars for the projection of...
Ngày tải lên: 22/02/2014, 10:20
Interest-Rate Risk in the Indian Banking System docx
... about the banking system In India, large reserve requirements imply that a policy of stretching out the yield curve innately involves forcing banks to increase the maturity of their assets Internationally, ... rise in interest rates upon banks in India In this paper, we measure the interest rate risk of a sample of major banks in India, using two methodologies The first consists of estimating the impact ... could happen in the banking system in the event of an increase in interest rates This paper offers some timely research inputs on these questions It seeks to obtain measures of the vulnerability...
Ngày tải lên: 06/03/2014, 14:20
Research "An empirical study of scale economies in the Chinese Railway System" pptx
Ngày tải lên: 16/03/2014, 03:20
Báo cáo Y học: The expression of glutathione reductase in the male reproductive system of rats supports the enzymatic basis of glutathione function in spermatogenesis doc
... protein metabolism in these cells Histone is rich in the basic amino acids, lysine and arginine, but contains no cysteine Protamine, which is replaced for hitstone via transit proteins during ... rich in both arginine and cysteine The cysteine sulfhydryls in protamine must form disulfide bond to package DNA into small sperm head during the maturation process Thus, while cysteine, a building ... protein and the mRNA were faint Effects of inhibitors of cGCS and GR on primary cultured testicular cells To investigate the contribution of de novo synthesis and the recycling of GSH to the intracellular...
Ngày tải lên: 17/03/2014, 17:20
SPENDING TO SURVIVE: Cancer Patients Confront Holes in the Health Insurance System potx
... facility 30 Spending to Survive: Cancer Patients Confront Holes in the Health Insurance System Catherine Guinn Florida Had to continue working during cancer treatments in order to maintain insurance ... maintain their health coverage after leaving a job COBRA allows people to temporarily continue the health insurance they had through their employer by paying the full cost of the insurance themselves ... struggle to maintain their coverage Others may have trouble buying coverage in the individual market even after they are in remission For those struggling to pay their premiums or facing mounting debt,...
Ngày tải lên: 22/03/2014, 16:21