... equivalent of 13 million IU of colistin base per day for 19 days whilst experiencing a doubling of plasma creatinine levels In a cohort of 115 patients, Cheng et al identified four cases of potential ... Nephrology Working Group of the European Society of Intensive Care Medicine: Prevention of acute kidney injury and protection of renal function in the intensive care unit Expert opinion of the Working ... article as: Spapen et al.: Renal and neurological sideeffectsof colistin in critically ill patients Annals of Intensive Care 2011 1:14 Page of Submit your manuscript to a journal and benefit...
... group, comparisons of ipsilateral-contralateral sides, e talc group, comparisons of ipsilateral-contralateral sides, f control group, comparisons of ipsilateral-contralateral sides, g when groups ... Department of Thoracic Surgery, GATA Military Medical Academy, Ankara, Turkey 2Department of Thoracic Surgery, Kırıkkale University, School of Medicine, Kırıkkale, Turkey 3Department of Pathology, ... directly to the contents of the pleural space by denudement of mesothelial cells after administration of sclerosing agents [22] After the discontinuation of production of the injectable tetracycline...
... Temporal variation in the appearance of different sideeffects [40] and differential responses to a change in dose of medication (in number, duration or severity ofside effects) [5] in different individuals, ... clinician-rated sideeffectsof drug treatment in schizophrenia - Clinical validation of a self-rating version of the UKU Side Effect Rating Scale (UKU-SERSPat) Nordic Journal of Psychiatry 2001, ... increased reporting of symptoms [31,32] It therefore follows that persons high in neuroticism are also likely to self-report greater sideeffectsof medication, and this is of considerable interest...
... alternative course of action with a better understanding of their likely consequences If managers have an enhanced awareness of the possible future effectsof alternative courses of action, for making ... take what measures to achieve the goals of the organization Provides opportunity to analyze alternative courses of action: Another source of importance of planning is that it permits managers ... Allocation: Planning is means of judicious allocation of strategic and scarce resources of the organization in the best possible manner for achieving strategic goals of the organization The strategic...
... of angiogenesis This is useful for testing anti-angiogenic drug effects, but presents difficulties in showing augmentation of angiogenic effects Although growth factor-depleted formulations of ... representative of the general orientation and assembly of HUVECs in the co-culture without significant loss of information, compared to higher magnifications of 10x or 20x As a confluent layer of fibroblasts ... Figure 13 Effectsof various concentrations of HDZ, CPX, PDCA and 10 ng/ml VEGF on optimized sequential co-cultures of fibroblasts and HUVECs; all images obtained at 4x magnification (A) Immunofluorescence...
... TABLE OF CONTENTS Page No Acknowledgements i Table of Contents ii Summary (Abstract) vi List of Figures ix List of Tables xi List of Abbreviations xii LITERATURE REVIEW ... required for formation of capillary like structures Figure 13 Effectsof various concentrations of HDZ, CPX, PDCA and 10ng/ml VEGF on optimized sequential co-cultures of fibroblasts and HUVEC ... applications by pre-vascularization of three dimensional scaffolds viii LIST OF FIGURES Figure Schematic representation of HIF-1α protein domain structures Figure Regulation of the HIF-1 transcription...
... 208 Glossary of the Pharmaceutical World 210 Addresses 217 Footnotes 218 Side Effects: Death Confessions of a Pharma-Insider May 2007 The peculiarity of my story is ... He is one of the most prominent and successful lawyers in lawsuits concerning the effectsof psychotropic medicines on humans, which we commonly label with the innocent words sideeffects In ... just as the x Side Effects: Death industry stipulates The influence of the pharmaceutical industry is often invisible A year ago, I had a telephone conversation with the editor of a famous German...
... give the opinion of one of the ablest physicians in Massachusetts, as to the use oftobacco "The chewingof tobacco, " says he, "is not necessary or useful in any case that I know of: and I have ... bonum, of the virtues oftobacco This sedative power will not be questioned, by those who have ever witnessed its peculiar effects The medicinal effectsof tobacco, as applied for the removal of ... its peculiar effects End of the Project Gutenberg EBook of A Dissertation on the Medical Properties and Injurious Effectsof the Habitual Use of Tobacco, by A McAllister *** END OF THIS PROJECT...
... incidence ofsideeffects was high; nearly out of 10 patients reported sideeffectsof treatment In the larger clinical trials on statins, no specific differences in the frequency ofsideeffects ... initiated lifestyle changes and therefore did not consider themselves to be in need of statin treatment Sideeffects The occurrence ofsideeffects was reported by 20 patients (29%) No significant ... degree of adherence to statin treatment despite a high incidence ofsideeffects Simvastatin is used in higher doses in hospital clinics compared with primary care, but the incidence ofside effects...
... real impact of skin toxicities on daily QoL, compared to generic tools as EORTC QLQ C-30 or SF-36 Conclusion This study documents the impact of skin sideeffects on quality of life of advanced ... oncological patients are considered [8,11,14,15] Respect to other conditions, the impact of skin sideeffects on colon cancer patients is relevant for all the three scales considered In particular ... scale, missing value was substituted by the mean of the total score of the scale [11] Higher scores indicate an increase impact of skin sideeffects on QoL, i.e a worse patient's QoL After informed...
... 17) mild side effects; 17% (n = 5) moderate side effects; none with severe sideeffects GT (n = 33): 15%(n = 5) no side effects; 55% (n = 18) mild side effects; 27% (n = 9) moderate side effects; ... effects; 3% (n = 1) severe sideeffects TT (n = 18): 5% (n = 1) no side effects; 56% (n = 10) mild side effects; 28% (n = 5) moderate sideeffects 11% (n = 2) severe sideeffects (Refer appendix ... concentrations of patients (R2 = 0.107, p = 0.23) 85% of patients experienced some form of EFV-related side effect The majority of patients, who had experienced sideeffects following initiation of Efavirenz...
... Table Percentage of subjects displaying each of the 17 sideeffectsof methylphenidate during each treatment condition (Parent Ratings)* Side Effect Total SideEffects Severe SideEffects Placebo ... frequencies of the 17 side effects, as well as the frequencies of severe side effects, between the placebo and active conditions Repeated measures analysis of variance (ANOVA) was used to detect the effects ... evaluation of the therapeutic response and sideeffects is often reported by the parents of the child with ADHD This may also lead to some correlation between therapeutic and sideeffects The aim of...
... Injection of type II bovine collagen in CFA 7x i.v treatment Collection of blood days after start of treatment Collection of blood days after end of treatment Collection of blood days after end of treatment ... glucocorticoid-related side- effects in both therapeutic modalities Eventually, the presence of liposomes and dexamethasone were monitored in plasma to correlate presence of the drug with the appearance of its side- effects ... significant inhibition of the collagen breakdown (Figure 2b) Side- effect profile of liposomal dexamethasone phosphate We next set out to directly compare glucocorticoid-mediated side- effects for both...
... points The uniqueness of GSE1276 is potentially due to the S9 treatment, which had unexpected broad effects on gene expression that may enhance or suppress the effectsof the tobacco smoke condensate ... y-axis is the ratio of the expression level of a particular sample versus that of a dummy reference sample (a) Plots of two rapidly reversible genes, CYP1B1 and ALDH3A1 (b) Plots of two irreversible ... expression consequences oftobacco smoke exposure in the small airway epithelium of never and current smokers (GSE3320) This suggests that the field of injury in response to tobacco smoke is similar...
... as a result of the increase of the redox potential and decrease of the sulphides (Saeki, 1993) The change in redox potential more strongly affected the speciation of Zn than that of Cu and Pb ... finding of Wong (1995) and Hofstede (1994) Although the leachable Cu increased with the composting process, the magnitude of leachable Cu in sludge compost without red mud amendment after 50 days of ... them that the quantities of metals extracted by CaCl2, expressed as a percentage of total metal content, were small pH of the sludge compost also affected the solubility of the metal hydroxides...
... composting of MSW although the increment was diminished by the addition of red mud (Hofstede, 1994) This was due to adsorption of soluble organic matter to red mud Plant availabilitv of heavy metals ... result of the redistribution of metal speciation during composting by humification of the organic matter Chromium speciation in municipal solid 0 day q 20th waste 21 of cornpasting Cr (w/kg) day of ... acidic conditions (Hofstede, 1994) Leachabilitv of heavv metals Over 80% of the total metal content in the artificial MSW was derived from the spiking and therefore the mobility of metals could be...
... study Strengths of the study are the use of randomized placebo-controlled double-blinded study design, the absence of thermogenic changes in the placebo group, the absence of adverse effects on blood ... consistency of the effectsof p-synephrine on metabolism in all treatment groups, and the increases in RMR in the treatment groups The weakness of this study is the small number (10) of subjects ... thermogenic effects is that noticeable changes in the mood states listed in Table often make subjects aware of whether or not they are receiving a placebo, thus undermining blinding of the study...
... discontinued the study because of severe sideeffects (Table 2) Figure Changes in serum concentration of CRP before and after thoracotomy in the study groups Table Sideeffects and complications in ... antiinflammatory effectsof flurbiprofen VAS scoring is a simple and often used method for evaluating variations in pain intensity Subjects are instructed to indicate the intensity of the pain by ... cyclooxygenase enzyme responsible for the release of mediators of inflammation (6) The aims of this study were to evaluate the serum levels of acute phase reactants, such as C-reactive protein...
... inner sideof the nuclear envelope http://www.medsci.org Int J Med Sci 2011, 102 Figure depicts the perinuclear localization of the fluorescence signals inside of the nuclear envelope of DU145 ... (right picture of the Figure 6) can be detected clearly The length of 200 bp matches with the DNA size of one nucleosome consisting of the peptide-based histone octamer and of a piece of DNA wound ... and the increase of fluorescence intensity inside of the nuclei of DU145 cells Figure visualizes the degree of the DNA damage in nuclei as a result of DNA strand breaks caused by ROS produced...