sickle cell disease in children

... Management of Sickle Cell Disease in Children Page 14 of 15 Appendix Monitoring Guidelines for Patients Receiving Intravenous Opioid Analgesia: Analgesia Continuous Opioid Infusion Intermittent ... 15-20% of infants and young children with sickle cell anemia die before the age of 5, usually of septicemia or meningitis In children under years of age with sickle cell disease, the predominant ... in a Sickle Cell Clinic Guidelines for Specific Clinical Settings: A Acute Painful Episode (Vaso Occlusive Disease) A vaso-occlusive crisis (VOC) is the most frequent complication of Sickle Cell...

Ngày tải lên: 05/03/2014, 12:20

... overwhelming majority of parents having children with sickle cell disease in Africa live and die without tests needed to establish the correct diagnosis Most infants with sickle cell disease are ... prevention of sickle cell disease and attitude towards their children with sickle cell disease Table 4: Participants’ knowledge about causes of sickle cell disease and attitudes towards children Variable ... causes of sickle cell disease and their attitudes toward children with sickle cell disease Table 2: Relationship of sex and attitude of the participants toward children with sickle cell disease Variable...

Ngày tải lên: 12/02/2014, 19:20

... syndrome in sickle cell haemoglobinopathy J Bone and Joint Surg (Br) 1995, 77B:310-312 11 Acurio MT, Friedman RJ: Hip Arthroplasty in patients with sickle cell Haemoglobinopathy J Bone and Joint Surg ... Homozygote sickle cell disease in patients above 20 years of age: follow-up of patients in Dakar Rev Med Interne 2003, 24:711-715 25 Platt OS, Brambilla DJ, Rosse WF: Mortality in sickle cell disease, ... Surgery 1992, 2:145-148 19 Lindberg L, Lindgren L: Bone and Joint infections Int Orthop 1997, 1:191198 20 Nade S: Acute septic arthritis in infancy and children J Bone and Joint Surg 1983, 65B:234-241...

Ngày tải lên: 20/06/2014, 04:20

... vital signs and maintaining them within tight ranges Anaesthesia from the beginning up to the end of surgery lasted 80 minutes Postoperative care, including fluid management and weaning off the respirator ... USA for his assistance in editing this manuscript Authors’ contributions RJ was involved in conceiving, designing and writing this manuscript MT was involved in providing a description of the ... Anesthesiological management in patients with sickle cell disease Anesthesiol Intensivmed Notfallmed Schmerzther 2002, 37:104-108 14 Oginni LM, Rufai HB: How safe is tourniquet use in sickle cell disease? Afr...

Ngày tải lên: 11/08/2014, 12:20

... A., & Zemel, B S (2004) Low vitamin D status in children with sickle cell disease Journal of Pediatrics, 145, 622-627 Center for Disease Control (2010) Sickle Cell Disease: Data and Statistics Retrieved ... study examining vitamin A status in children with SCD-SS revealed that the mean serum retinol level was suboptimal in 66% of the children (Schall, Zemel, Kawchak, Ohene-Frempong, & Stallings, 2004) ... studies examining vitamin D, vitamin A, and zinc status suggest that increased nutritional demands are likely contributing factors to the micronutrient deficiencies seen in SCD-SS Affected children...

Ngày tải lên: 12/02/2014, 19:20

... in determining discriminant validity of the PedsQL™ Family Impact Module in our population of children with sickle cell disease, we collected data on the disease status of the children with sickle ... of children with severe sickle cell disease reported significantly worse scores in the communication and worry scales than children with mild sickle cell disease and children without sickle cell ... children with and without sickle cell disease In addition, we also compared parents of children with sickle cell disease to parents of children without sickle cell disease and without other co-morbidities...

Ngày tải lên: 18/06/2014, 18:20

... life in children with sickle cell disease J Behav Med 2002, 25:269-283 15 Palermo TM, Riley CA, Mitchell BA: Daily functioning and quality of life in children with sickle cell disease pain: relationship ... functioning of children with sickle cell disease and comparison peers Journal of Pediatric Hematology/Oncology 2004, 26:642-648 11 Panepinto JA: Health-related quality of life in sickle cell disease ... of HRQoL, encompassing all three components of children s well-being, is still in its infancy in children with SCD [11] For example, compared to over 400 studies on HRQoL in children with cancer,...

Ngày tải lên: 20/06/2014, 15:20

... of research investigating patients with concomitant asthma and sickle cell disease Table 2: Results in children with sickle cell disease with and without asthma Patients with Sickle Cell & Asthma ... pulmonary failure Medicine 1998, 67:66-76 Nickerson B, Browning I, Vichinsky E, Weiner S: Cooperative Study of Sickle Cell Disease Pulmonary function in children with sickle cell disease (abstract) ... compared to children with sickle cell disease alone The significance of these findings relates to the hypothesis that appropriately aggressive treatment of asthma in children with sickle cell disease...

Ngày tải lên: 13/08/2014, 13:22

... GVHD is initiated, T-cells produce additional proinflammatory cytokines, including tumor necrosis fac­ tor (TNF)-α, interferon (IFN)-γ, and interleukin (IL)-2, which in turn attract more T-cells ... (Th2) cells can initiate a response against autoantigens leading to B -cell hyperre­ activity and production of autoantibodies, causing targetorgan damage, including skin, mucosa, eyes, joints, ... rash and itching may occur; the skin may become scaly; the skin may heal by scarring; hair loss may accompany the skin injury Look for dry eyes: no tears, constant rubbing and blinking; sensitivity...

Ngày tải lên: 12/02/2014, 19:20

... major genotypes within the definition of SCD: homozygous sickle cell (SS) disease, sickle haemoglobin C (SC) disease, sickle cell bz thalassaemia (S bz thalassaemia) and sickle cell b0 thalassaemia ... endocrine cause.3 Determination of gonadotropin concentrations in 40 children with sickle cell anaemia (5–16 yrs) showed a significant increase in LH in children aged 5–10 years and normal levels in ... composition in children with sickle cell disease Am J Clin Nutr 2002; 76:218–25 63 Badaloo A, Jackson AA, Jahoor F Whole body protein turnover and resting metabolic rate in homozygous sickle cell disease...

Ngày tải lên: 12/02/2014, 19:20

... treatment seeking for pain from sickle cell disease: qualitative study British Medical Journal, 318, 1585–1590 McCrae, J.D & Lumley, M A (1998) Health status in sickle cell disease: examining the roles ... Keith, B.R., Tota-Faucette, M., Noll, S & Kinney, T.R (1993) Sickle cell disease pain in children and adolescents: change in pain frequency and coping strategies over time Journal of Pediatric ... stress in sickle cell disease: an analysis of daily pain records International Journal of Behavioural Medicine, 5, 185–203 Powars, D.R (2000) Management of cerebral vasculopathy in children with sickle...

Ngày tải lên: 14/03/2014, 11:20

... Guidelines for the management of the acute painful crisis in sickle cell disease Br J Haematol 2003, 120(5):744-752 Serjeant GR: The dilemma of defining clinical severity in homozygous sickle cell ... death in patients with sickle cell disease Blood 2006, 107(6):2279-2285 Steinberg MH: Predicting clinical severity in sickle cell anaemia Br J Haematol 2005, 129(4):465-481 Cumming V, King L, ... DH: Sickle cell disease: Pain, coping and quality of life in a study of adults in the UK Br J Health Psychol 2002, 7(Part 3):331-344 Anie KA, Steptoe A: Pain, mood and opioid medication use in sickle...

Ngày tải lên: 18/06/2014, 19:20

... Guidelines for the management of the acute painful crisis in sickle cell disease Br J Haematol 2003, 120(5):744-752 Serjeant GR: The dilemma of defining clinical severity in homozygous sickle cell ... death in patients with sickle cell disease Blood 2006, 107(6):2279-2285 Steinberg MH: Predicting clinical severity in sickle cell anaemia Br J Haematol 2005, 129(4):465-481 Cumming V, King L, ... DH: Sickle cell disease: Pain, coping and quality of life in a study of adults in the UK Br J Health Psychol 2002, 7(Part 3):331-344 Anie KA, Steptoe A: Pain, mood and opioid medication use in sickle...

Ngày tải lên: 20/06/2014, 16:20

... MCD: minimal change disease; PSGN: poststreptococcal glomerulonephritis; RF: rheumatoid factor; SCA: sickle cell anemia; SCD: sickle cell disease; SCN: sickle cell nephropathy; VDRL: Venereal Disease ... PC, Wilkinson AH, Lew SQ: Renal abnormalities in sickle cell disease Kidney Int 2000, 57:1-8 Ataga KI, Orringer EP: Renal abnormalities in sickle cell disease Am J Hematol 2000, 63(Suppl 4):205-211 ... Proteinuria, a common finding in adults with SCD, may progress to the nephrotic syndrome Proteinuria, hypertension and increasing anemia predict ESRD [7] The incidence of renal failure in patients with...

Ngày tải lên: 11/08/2014, 00:22

... depression and loneliness in this disease group Methods Sampling The Jamaica Sickle Cell Cohort Study (JSCCS) incorporates all patients with SCD detected during the screening of 100,000 consecutive ... comprehensive sickle cell clinic (SCU) located at the University of the West Indies in Kingston, Jamaica for routine health maintenance checks and for all significant sick events in an effort ... frequent painful crises and lower prevalence of leg ulceration (results not shown) This finding may point to lower coping mechanisms in those with the less severe form of disease; past findings have...

Ngày tải lên: 11/08/2014, 16:22

... index of clinical severity in individuals with sickle cell anemia Am J Hematol 1992, 41:227-231 58 Natta C, Machlin L, Brin M: A decrease in irreversibly sickle erythrocytes in sickle cell anemia ... capacity in paediatric patients with homozygous sickle cell disease Eur J Clin Nutr 1989, 43:609-614 63 Houston PE, Rana S, Sekhsaria S, Perlin E, Kim KS, Castro OL: Homocysteine in sickle cell disease: ... endothelial cells to RBCs sickled in vitro results in a fourfold to eightfold induction of endothelin-1 mRNA [51] Similarly, we demonstrated increased endothelin-1 mRNA and protein levels in endothelial...

Ngày tải lên: 12/08/2014, 18:20

... infarction in a thirty five year old patient with Sickle cell Hemoglobin C disease (Hb SC) That psychosis in this patient was complicating brain tissue silent infarcts cannot be ruled out in view ... children with sickle cell disease Dev Med Child Neurol 1991, 33(12):1087-94 Yang YM, Cepeda M, Price C, Shah A, Mankad V: Depression in children and adolescents with sickle cell disease Arch Pediatr ... Psychiatric morbidity in patients with sickle cell anemia West Afr J Med 1996, 15(4):196-200 Pegelow CH, Wang W, Granger S, Hsu LL, et al.: Silent infarcts in children with sickle cell anemia and abnormal...

Ngày tải lên: 13/08/2014, 18:21

... Occasional abdominal pain, difficulty gaining weight and height Prior history of anemia Difficulty gaining weight and height Prior history of anemia Frequent abdominal pain, difficulty gaining weight ... covering socioeconomic and demographic aspects as well as complaints related to celiac disease (abnormal intestinal rhythm, abdominal pains, flatulence, recurrent aphthous ulcers, difficulty gaining ... gastroenterology clinic to continue investigation of celiac disease Data were stored in Epi-Info version 6.0 Seropositivity was calculated as the proportion of individuals in the sample with...

Ngày tải lên: 12/02/2014, 19:20

... invasive examination method, we fundamental when dealing with chronic patients indicated lung biopsy, since it offers more objective informa- Epidemiological research into interstitial lung diseases ... Clinical presentation of interstitial lung disease in children Pediatr Respir Rev 2004;5:98-100 19 Barbato A, Panizzolo C, Cracco A, de Blic J, Dinwiddie R, Zach M Interstitial lung disease in ... patients Wheezing is less common but of ILD in children and, in our hospital, became available only it was observed in 11 patients in 1997 As a result, in five cases HRCT scans were not In the 13...

Ngày tải lên: 12/02/2014, 19:20

... Laboratories, Washington DC, 1999 Sickle Cell Disease Guideline Panel Sickle Cell Disease: Screening, Diagnosis, Management, and Counseling in Newborns and Infants Clinical Practice Guideline No AHCRP ... Gallagher D, Kinney TR, et al Mortality in children and adolescents with sickle cell disease Pediatrics 1989;84:500-8 Sickle Cell Disease Guideline Panel Sickle Cell Disease: Screening, Diagnosis, ... Genet 1991;48:452-9 Sickle Cell Disease Guideline Panel Sickle Cell Disease: Screening, Diagnosis, Management and Counseling in Newborns and Infants Clinical Practice Guideline No AHCPR Pub No...

Ngày tải lên: 21/02/2014, 12:20