sickle cell anaemia disseminated intravascular coagulation

... used to replenish the consumed factors Packed red cells may also be required if the haemolytic anaemia is severe enough ᭿ DISSEMINATED INTRAVASCULAR COAGULATION What will haematologic investigations ... SURGICAL CRITICAL CARE VIVAS What type of anaemia may be seen in DIC and why? Microangiopathic haemolytic anaemia may be seen due to red cell fragmentation caused by fibrin deposition in ... necessary for mucosal integrity What is the result of mucosal atrophy? ᭹ Loss of cellular adhesion and development of cellular channels ᭹ Translocation of bacteria across the bowel wall into the...

Ngày tải lên: 01/11/2013, 09:20

... máu không "đông", mà không "loãng" Trong mạch, luôn có quân giưã hai lực lượng chống báng nhau: "coagulation" "fibrinolysis" Bs Nguyễn Tài Mai, ...

Ngày tải lên: 13/07/2014, 22:20

... Successful surgical resection of infected left atrial myxoma in a case complicated with disseminated intravascular coagulation and multiple cerebral infarctions: case report Journal of Cardiothoracic ... of the low platelet count after the operation and to prevent hemorrhagic complications, no anticoagulation therapy was performed in during the postoperative course But he suffered a brain haemorrhage...

Ngày tải lên: 10/08/2014, 09:21

... patient because baseline localized intravascular coagulation progressed to DIC, thus depleting the coagulation factors LMWH could not prevent the consumption of the coagulation factors, which is a ... whether there is a platelet pooling like in KMS as opposed to continuous local intravascular coagulation that consumes coagulation factors, leading to the formation of thrombin and fibrin within ... by the Editor-in-Chief of this journal Abbreviations CT: computed tomography; DIC: disseminated intravascular coagulation; KMS: Kasabach-Merritt syndrome; KTWS: Klippel-Trenaunay-Weber syndrome;...

Ngày tải lên: 11/08/2014, 12:20

... scoring system for disseminated intravascular coagulation Thromb Haemost 2001, 86:1327-1330 22 Osterud B, Bjorklid E: The tissue factor pathway in disseminated intravascular coagulation Semin ... receiver operating characteristics curve; CM: classical monocyte; DIC: disseminated intravascular coagulation; DM: dendritic cell- like monocyte; IL: interleukin; IM: inflammatory monocyte; ISTH: ... H: Disseminated intravascular coagulation N Engl J Med 1999, 341:586-592 Conway EM, Rosenberg RD: Tumor necrosis factor suppresses transcription of the thrombomodulin gene in endothelial cells...

Ngày tải lên: 14/08/2014, 08:21

... Issues 58 Help and Support 60 A What is Sickle Cell Disease? B What Causes Sickle Cell Disease? C Comprehensive Sickle Cell Disease Care Plan: Years to Adult D Common Medical ... blood cells from the blood and to help fight infections Enlargement and Scarring The type of sickle cell disease a person has affects the spleen differently With sickle cell anemia (SS) and sickle ... child with sickle cell disease It can be helpful to teach all of your children about sickle cell disease If they have questions that you can’t answer, let them ask the staff at the sickle cell center...

Ngày tải lên: 12/02/2014, 12:20

... as 1-2% of children have sickle cell anemia or HbSC disease, sickle cell anemia is a public health and individual dilemma Apart from the attendant high morbidity, sickle cell disease also inflicts ... knowledge about the cause(s) of sickle cell disease of the participants and their attitude towards their children with sickle cell disease Knowledge of the impact of sickle cell disease will not make ... knowledge about the cause(s) of sickle cell disease and the attitude of parents towards their children with sickle cell disease Hypothesis 4: Knowledge of the impact of sickle cell disease will not make...

Ngày tải lên: 12/02/2014, 19:20

... children with sickle cell disease Journal of Pediatrics, 145, 622-627 Center for Disease Control (2010) Sickle Cell Disease: Data and Statistics Retrieved from http://www.cdc.gov/ncbddd/sicklecell/data.html ... Hoppe, C., Telen, M J.; Investigators, Comprehensive Sickle Cell Centers (2010) Definitions of the phenotypic manifestations of sickle cell disease American Journal of Hematology, 85, 6-13 Buison, ... outcomes in young children with sickle cell disease Journal of Pediatrics, 145, 99-106 Silva, C M., & Viana, M B (2002) Growth deficits in children with sickle cell disease Archives of Medical...

Ngày tải lên: 12/02/2014, 19:20

... of children with sickle- cell disease Hum Biol 1976; 48:429–37 25 Booker CR, Scott RB, Ferguson AD Studies in sickle cell anaemia Xxii Clinical manifestations of sickle cell anaemia during the ... within the definition of SCD: homozygous sickle cell (SS) disease, sickle haemoglobin C (SC) disease, sickle cell bz thalassaemia (S bz thalassaemia) and sickle cell b0 thalassaemia (S b0 thalassaemia).7 ... CI Nutritional megaloblastic anaemia associated with sickle cell states Blood 1959; 14:535–47 MacIver JE, Went LN Sickle- cell anaemia complicated by megaloblastic anaemia of infancy Br Med J 1960;...

Ngày tải lên: 12/02/2014, 19:20

... S Allele and Sickle Cell Disease http://www.cdc.gov/genomics/hugenet/reviews /sickle. htm An excellent article about sickle cell genetics and epidemiology The Comprehensive Sickle Cell Centers ... thal Sickle cell disease-S βo DIAGNOSIS AND COUNSELING W ORLD W IDE W EB R ESOURCES SICKLE CELL AND GENETIC WEB SITES Sickle Cell Disease Association of America (SCDAA) http://www.sicklecelldisease.org ... βs Sickle cell disease-SS SCD-SS βs / βc Sickle cell disease-SC SCD-SC βs / / βo thalassemia βs / β+ thalassemia thalassemia SCD-S βo thal Sickle cell disease-S β+ thalassemia SCD-S β+ thal Sickle...

Ngày tải lên: 21/02/2014, 12:20

... Introduction Sickle Cell Disease Sickle cell disease is a genetic disorder that decreases life expectancy by 25 to 30 years and affects approximately 80,000 Americans.1,2 Sickle cell disease ... causing the red blood cell to assume a sickle shape and making the cell both rigid and fragile These distorted cells obstruct the blood vessels and may disrupt endothelial cell function, leading ... Observational Studies on Children with Sickle Cell Disease .36 viii Table Efficacy of Hydroxyurea in Observational Studies on Adults with Sickle Cell Disease .39 Table...

Ngày tải lên: 05/03/2014, 10:20

... Children with Sickle Cell Disease Pediatrics 2002 Mar;109 (3): 526-35 Steinberg MH, Management of Sickle Cell Disease NEJM 1999 Apr; 340 (13): 1021-30 Fixler J, Styles L Sickle Cell Disease Pediatr ... of febrile illness in infants and young children with sickle cell anaemia J Pediatr 1990; 117 (5): 736-739 [a retrospective review of sickle cell patients with fever managed with IV ceftriaxone ... Uncertain diagnosis i.e sickle cell crisis vs osteomyelitis Follow up • The patient should be assessed for long-term management by a paediatrician and/or followed in a Sickle Cell Clinic Guidelines...

Ngày tải lên: 05/03/2014, 12:20

... with sickle cell disease: a report from the Cooperative Study of Sickle Cell Disease Journal of Pediatrics, 139, 391–397 Whitten, C.F & Fischoff, J (1974) Psychosocial effects of sickle cell ... family and their child with sickle cell anaemia Journal of Family Practice, 15, 23–32 Hasan, S P., Hashmi, S., Alhassen, M., Lawson, W & Castro, O (2003) Depression in sickle cell disease Journal of ... with sickle cell anaemia British Journal of Haematology, 108, 666– 678 Prohovnik, I., Sano, M., DeVivo, D., Hurlet, A., Keilp, J & Piomelli, S (1995) Frontal lobe dysfunction in sickle- cell anemia...

Ngày tải lên: 14/03/2014, 11:20

... 1) sickle cell disease without co-morbidities (n = 47), 2) sickle cell disease with neurobehavioral co-morbidities (n = 23), 3) sickle cell disease with medical co-morbidities (n = 12), 4) sickle ... of children with and without sickle cell disease In addition, we also compared parents of children with sickle cell disease to parents of children without sickle cell disease and without other ... with severe sickle cell disease reported significantly worse scores in the communication and worry scales than children with mild sickle cell disease and children without sickle cell disease...

Ngày tải lên: 18/06/2014, 18:20

... pulmonary hypertension, and death in patients with sickle cell disease Blood 2006, 107(6):2279-2285 Steinberg MH: Predicting clinical severity in sickle cell anaemia Br J Haematol 2005, 129(4):465-481 ... Depression, disease severity, and sickle cell disease J Behav Med 1999, 22(2):115-126 Ohaeri JU, Shokunbi WA, Akinlade KS, Dare LO: The psychosocial problems of sickle cell disease sufferers and their ... 40(7):955-960 Jacob E: The pain experience of patients with sickle cell anemia Pain Manag Nurs 2001, 2(3):74-83 Anie KA, Steptoe A, Bevan DH: Sickle cell disease: Pain, coping and quality of life in a...

Ngày tải lên: 18/06/2014, 19:20

... peers, but not find an association with disease severity measured as sickle cell type.[13] Although pain and other sickle cell complications show an association with decrements in engagement ... with sickle cell disease (SCD) Detailed descriptions of the participant recruitment and procedures are given in previous publications.[17] All patients at an urban Comprehensive Sickle Cell Center ... part through a Comprehensive Sickle Cell Center Grant P60-HL-62148 The authors wish to thank the patients and their families of the Marian Anderson Comprehensive Sickle Cell Center for their participation...

Ngày tải lên: 18/06/2014, 19:20

... Perculiar elongated and sickle- shaped red blood corpuscles in a case of severe anaemia Trans Assoc Am Physicians 1910, 25:553-561 Pauling L, Itano HA, Singer SJ: Sickle cell anaemia, a molecular ... outcomes in patients with sickle cell disease and frequent vaso-occlusive crises Am J Med Sci 2003, 325:107-109 27 Yetunde A, Anyaegbu CC: Profile of the Nigerian sickle cell anaemia patients above ... Homozygote sickle cell disease in patients above 20 years of age: follow-up of patients in Dakar Rev Med Interne 2003, 24:711-715 25 Platt OS, Brambilla DJ, Rosse WF: Mortality in sickle cell disease,...

Ngày tải lên: 20/06/2014, 04:20

... of sickle cell disease: the road to understanding the sickle cell disease clinical phenotype Blood Rev 2005, 19:99-110 Thomas VJ, Taylor LM: The psychosocial experience of people with sickle cell ... report about the previous 24 hours: the worst sickle cell pain intensity, on a scale from (none) to (unbearable), whether or not they were in a sickle cell crisis, and whether they had gone for ... Pain in sickle cell disease: Rates and risk factors N Engl J Med 1991, 325:11-16 Platt OS, Brambilla DJ, Milner PF, Rosse WF, Milner PF, Castro O, Steinberg MH, Klug PP: Mortality in sickle cell...

Ngày tải lên: 20/06/2014, 15:20

... is a challenge Acute episodes of pain are the principal symptom of sickle cell disease (SCD) In the Cooperative Study of Sickle Cell Disease (CSSCD), an analysis of painful crises in 3,578 patients ... patientyear in sickle β0-thalassemia and 0.4 episodes per patientyear in SC and sickle β+-thalassemia The rates varied widely within each of these groups: 39% of patients with sickle cell anemia ... reduced painful sickle cell episodes, hospitalizations for painful episodes, acute chest syndrome and total number of units of blood transfused Although patients with sickle cell anemia (SS)...

Ngày tải lên: 20/06/2014, 15:20

... Published: 26 October 2010 References Stuart MJ, Nagel RL: Sickle- cell disease Lancet 2004, 364:1343-1360 Roberts I, de Montalembert M: Sickle cell disease as a paradigm of immigration hematology: ... complications in sickle cell disease Br J Haematol 2005, 129:723-729 Barakat L, Lash LA, Lutz MJ, Nicolaou DC: Psychosocial Adaptation of Children and Adolescents with Sickle Cell Disease In Comprehensive ... youngsters with sickle cell disease Child Dev 1996, 67:423-436 Noll RB, Reiter-Purtill J, Vannatta K, Gerhardt CA, Short A: Peer relationships and emotional well-being of children with sickle cell disease:...

Ngày tải lên: 20/06/2014, 15:20