serglycin the master of the mast cell
Báo cáo khoa học: "Role of mucosal mast cells in visceral hypersensitivity in a rat model of irritable bowel syndrome" ppt
... distension (Fig 4) However, the same dose of mast cell stabilizer effectively alleviated the visceral hypersensitivity in IBS rats By the pretreatment of doxantrazole, the AUC of the stimulusresponse ... that mast cells can synthesize a variety of substances, and these substances can sensitize sensory neuron [4] Although it is beyond the scope of the present study to identify the most important mast ... an evidence of MMC degranulation [5] The number of MMC was expressed as mean number of cells per mm2, and the degranulation rate of MMC was expressed as a percentile proportion of the degranulated...
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Báo cáo khoa học: Arg143 and Lys192 of the human mast cell chymase mediate the preference for acidic amino acids in position P2¢ of substrates pdf
... indicated at the bottom of (A) (B, D) The cleavage of a number of substrates by HC The names and sequences of the different substrates are indicated above the pictures of the gels The times of cleavage ... acid of Fig Analysis of cleavage specificity by the use of new types of recombinant protein substrate (A) The overall structure of the recombinant protein substrates used for analysis of the efficiency ... charge of their side chains Verifying the consensus sequence by the use of a new type of recombinant protein substrate In order to verify the results from the phage display analysis, a new type of...
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Báo cáo khoa học: The heterogeneity of mast cell tryptase from human lung and skin Differences in size, charge and substrate affinity ppt
... resolve the relative proportions of the two enzymes.) pH prole Fig Mathematical modeling of the behavior of a mixture of isoforms of an enzyme (A) Hanes plot of a theoretical mixture of isoforms of ... values of Kmi, the terms of the denominator of Eqn will always be less than the corresponding terms in Eqn As the number of terms is the same for both equations, the value of the y-intercept for the ... (Dynal) Kimura staining indicated that the purity of mast cells thus obtained ranged from 65% to 95% of all nucleated cells Isolation of skin mast cells Mast cells were isolated as described previously...
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Báo cáo sinh học: " No relationship between the distribution of mast cells and the survival of stage IIIB colon cancer patients" pdf
... that, although the counts of mast cells varied with location, none of the mast cell counts was correlated with the 5-year survival rate These data argue against the hypothesis that mast cells are ... MCCstroma, the count of tryptase-positive mast cells in the cancer stroma of the primary colon tumor; MCCadjacent, the count of tryptase-positive mast cells in the normal mucosa adjacent to the colon ... MCCstroma, the count of tryptase-positive mast cells in the cancer stroma of the primary colon tumor; MCCadjacent, the count of tryptase-positive mast cells in the normal mucosa adjacent to the colon...
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báo cáo hóa học:" No relationship between the distribution of mast cells and the survival of stage IIIB colon cancer patients" potx
... that, although the counts of mast cells varied with location, none of the mast cell counts was correlated with the 5-year survival rate These data argue against the hypothesis that mast cells are ... MCCstroma, the count of tryptase-positive mast cells in the cancer stroma of the primary colon tumor; MCCadjacent, the count of tryptase-positive mast cells in the normal mucosa adjacent to the colon ... MCCstroma, the count of tryptase-positive mast cells in the cancer stroma of the primary colon tumor; MCCadjacent, the count of tryptase-positive mast cells in the normal mucosa adjacent to the colon...
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Báo cáo y học: "The role of mast cells and fibre type in ischaemia reperfusion injury of murine skeletal muscles" pot
... muscles (p < 0.05) There were no mast cells in the C57/DBA Wf/Wf skeletal muscles as expected However, there was twice the density of mast cells in their normal compared to their heterozygous ... fewer mast cells ranging from 0.3 to 2.3 mast cell profiles/ mm2 In Wf/Wf mice, the mast cell density was markedly reduced in both tongue (1.95 ± 0.42) (Figure 2) and skin (6.73 ± 3.27) No mast cells ... [5] Mast Cell Staining Mast cells were selectively stained by routine toluidine blue [8] and chloroacetate esterase (CAE) methods [9] Mast Cell Density An overview of mast cell content in the...
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Báo cáo y học: "Baicalein inhibits IL-1β- and TNF-α-induced inflammatory cytokine production from human mast cells via regulation of the NF-κB pathway" pot
... http://www.clinicalmolecularallergy.com/content/5/1/5 of patients with asthma [5], the skin of patients with urticaria [6], and the joints of patients with arthritis [7], illustrates the association of mast cells in these inflammatory ... microscope [18] The ratio of live to dead cells (cell viability) was determined The cell viabilities of the drug groups in this study were ranging from 93 to 95%, while that of medium control ... 4analysis of effects of BAI on the gene expression of IL-6, IL-8, and MCP-1 in IL-1β- and TNF-α-activated HMC-1 cells RT-PCR RT-PCR analysis of effects of BAI on the gene expression of IL-6, IL-8,...
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Báo cáo y học: "Probing the mystery of Chinese medicine meridian channels with special emphasis on the connective tissue interstitial fluid system, mechanotransduction, cells durotaxis and mast cell degranulation" ppsx
... and other specific receptors that are near mast cell migration tracks would have much better chances of interaction with the mast cells, leading to the degranulation of these "storage cells" The ... What is the physiological function of mast cells? Exp Dermatol 2003, 12(6):886-910 Deng Y, Zeng T, Zhou Y, Guan X: The influence of electroacupuncture on the mast cells in the acupoints of the stomach ... the visceral hili and tunicae Dang et al [4]'s work indicated that out of 11 of the acupoints of the lung meridian were on the periosteum, one on the perineurium of the (radial) nerve, Page of...
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ERK1 AND ERK2 IN HEMATOPOIESIS, MAST CELL FUNCTION, AND THE MANAGEMENT OF NF1-ASSOCIATED LEUKEMIA AND TUMORS
... pharmacological inhibition of the tumorous mass Therefore, therapeutic strategies targeting components of the tumor microenvironment, including vascular cells and infiltrating mast cells, may prove viable ... efficient visualization of low cell numbers The ability of the FACSAria to accurately perform single -cell plating is regularly evaluated by 25 members of the Indiana University School of Medicine Flow ... (9-13) By the 1980s, mast cells were widely-recognized inflammatory effectors and hallmark histological features (albeit of unknown significance) of the neurofibroma Vincent Riccardi first hypothesized...
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A research proposal submitted in partial fulfillment of the requirements for the degree of Master of Business Administration
... that the price was all-important, and every penny counted The supermarket was generally accepted as the food retailer until the years 1970s By the end of the decade, the changing lifestyle of the ... Demographic profile of supermarkets’ non-users and heavy-users The demographic profile of heavy users in the sample is similar to the profile described for the whole sample (table 4.16 The figures ... 32% the same as the position in Hong Kong in 1980 The figure is expected to rise to 75% by the end of the nineties, less than half the time it took in Hong Kong In the Philippines, despite the...
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Tài liệu The Master of the World doc
... undertake the ascent of the mountain, with the aid of two experienced guides These men had ascended Mt Mitchell and others of the highest peaks of the Blueridge They had never, however, attempted the ... On the morrow, the twenty-ninth of April, we started again at dawn By the end of this second day, we expected to reach the farm of Wildon at the foot of the mountain The country was much the ... And the engineers had not yet spoken their last word Neither were the navies of the world behind The cruisers, the torpedo boats, the torpedo-destroyers, could match the swiftest steamers of the...
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Tài liệu Báo cáo khoa học: MicroRNA-23a promotes the growth of gastric adenocarcinoma cell line MGC803 and downregulates interleukin-6 receptor pdf
... confirmed the active role of miR-23a in the growth promotion of malignant cells The fundamental function of miRNAs is to regulate their targets by direct cleavage of mRNA or by inhibition of protein ... in further studies Collectively, our studies demonstrate that miR-23a potently promotes the growth of the gastric adenocarcinoma cell line MGC803, providing the first proofof-concept that there ... complementary to the miR-23a seed region Three binding sites of miR-23a were found in the 3¢ UTR of IL6R mRNA (Fig 3A) To confirm that miR-23a can bind to these regions and suppress the expression of the target...
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Tài liệu Báo cáo Y học: Targeting of malate synthase 1 to the peroxisomes of Saccharomyces cerevisiae cells depends on growth on oleic acid medium pptx
... absent from the lane corresponding to the mls1D mutant (arrow; Fig 1A), thereby con®rming the speci®city of the antibody Application of the antibody to thin sections of wild-type cells grown ... acid medium [33], the issue of the partitioning of the glyoxylate cycle in cells grown under fatty acid-medium conditions has hitherto remained open We showed here that one of the key glyoxylate-cycle ... position [21] The signi®cance of this similarity is currently being addressed Demonstration of the cytosolic location of Mls1p in wild-type cells grown on ethanol completes the picture of the extra-peroxisomal...
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Master of the Moondog pot
... Don't let them get away I'll wring the ears off the lot of you if they get to the spaceport He was there; he was the one who spotted us He can identify my ship Now get out and find them I'll ... night They fled back, some of them, to the black ship which had brought them And there, they ran straight into the waiting arms of a detail from Space Patrol headquarters T od Denver's friend, the ... Bride of the Dark One The outcasts; the hunted of all the brighter worlds, crowded onto Yaroto But even here was there salvation for Ransome, the jinxscarred acolyte, when tonight was the night of...
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Báo cáo khoa học: A role for serglycin proteoglycan in granular retention and processing of mast cell secretory granule components ppt
... storage of these compounds, the strategy in the next set of experiments was to follow the fates of the SG-dependent proteases when SG was absent To address these issues, we examined the expression, ... that the amount of actual sulfated PGs is not directly correlated with the level of SG mRNA, and it was therefore of interest to also follow the levels of sulfated PGs during the course of MC ... to determine whether the lack of SG affected the actual assembly of granules and whether secretory granules were also functional in the absence of SG To this end, bone marrow cells were recovered...
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FIGURATIVE SCULPTURE IN PAPER CLAY - IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE DEGREE OF MASTER OF FINE ARTS ppt
... Jung’s conception of a “shadow side” to the psyche De Staebler feels that we have gained comfort and technology at great expense to the health of the environment and the health of the human psyche ... for firing onto the 20° F concrete and hosed them off, while they were red hot, with freezing water They survived The velvety smoke that permanently penetrating the surfaces of my figures seemed ... is the subject of this piece Female/male, anima/animus, yin/yang, positive/negative, black/ white the number two Each of these examples illustrates that there are two sides, and the two sides of...
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Báo cáo khoa học: Cloning, expression and interaction of human T-cell receptors with the bacterial superantigen SSA ppt
... Consequently, the molecular studies of the interaction of SAgs with their specifics ligands will not only advance understanding of the physiological mechanisms of these molecules, but may lead to the development ... treatment of several pathologies and because of the potential use of the toxins as biological weapons Alteration of their MHC and TCR binding capacity by site directed mutagenesis could be useful in the ... and alkylation, and mutation of the Cys implicated in the intermolecular disulfide bridge Analysis of the three-dimensional structure of SSA [31] to determine which of the remaining three Cys residues...
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Báo cáo khoa học: Investigation of the kinetics and order of tyrosine phosphorylation in the T-cell receptor f chain by the protein tyrosine kinase Lck potx
... over 30 The excess of ATP ensured that none of the reactions were rate-limited by ATP concentration The levels of incorporation of 32P into the peptide were used to calculate the kinetics of phosphorylation ... structure The two groups of peaks at 6.85 and 7.15 p.p.m correspond to the aromatic resonances of the seven tyrosines in the protein, and the inset 2D expansion of the 1H-1H COSY shows that the seven ... Phosphorylation of the T -cell receptor f chain (Eur J Biochem 270) 2373 Fig 1H-NMR spectroscopy of His-cTCRf (A) Expansion of the 1D 1H spectrum of His-cTCRf The aromatic resonances of the tyrosines...
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Student Handbook for the Master of Science Programs in: Business & Management pdf
... multiplying the value by the ECTS credits for each course and then calculating the sum of the products This sum is then divided by the sum of the ECTS credits to give the GPA as shown in the formula ... even if they have not completed every format of examination for the course 3.4 RULES AND REGULATIONS FOR THE MASTER THESIS 3.4.1 Prerequisites In order to commence writing the Master thesis the student ... Guidelines for the Master Thesis During semester or students write their Master thesis in Management Please see Section 3.4/Chapter for general rules and regulations for the Master thesis 1.1.4...
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