self distribution and other alternatives to traditional distribution

... ethical responsibility to readers, and to the author/s from whom s/he is borrowing, to respect others’ ideas and words, to credit those from whom we borrow, and whenever possible, to use one’s own ... understanding of the ideas and terminology being used A responsible writer has an ethical responsibility to readers, and to the author/s from whom s/he is borrowing, to respect others’ ideas and ... without giving credit to its originator In the sciences, as in most other scholarly endeavors, ethical writing demands that ideas, data, and conclusions that are borrowed from others and used as the...

Ngày tải lên: 26/03/2014, 14:08

... me to alter it now." However, she took him by means of an omnibus to a hat shop and bought him another hat and put it on his head, and made a present of the old one to the shop assistant, and ... and make up their minds to take stock and count the till, and the disillusion lays them low, and they struggle into the living-room and murmur: "I shall never have that beautiful furniture, and ... only six or seven; and it needs only an impulse, an effort, a system, in order gradually to cure the mind of its slackness, to give "tone" to its muscles, and to enable it to grapple with the...

Ngày tải lên: 29/03/2014, 12:20

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Ngày tải lên: 07/07/2014, 01:20

... released into the circulation from the bone marrow and the liver and are transported to the skin, where they absorb incident energy both in the Soret band, around 400 nm (short visible), and to a lesser ... and/ or release of vasoactive mediator(s), or cytokines, that diffuse to the dermal vasculature to evoke vasodilatation The action spectrum for sunburn erythema includes the UV-B and UV-A Photons ... dendritic cells known as melanocytes and is packaged into melanosomes that are transferred via dendritic process into keratinocytes, thereby providing photoprotection and simultaneously darkening the...

Ngày tải lên: 07/07/2014, 01:20

... sunscreens and the induction of hardening by the cautious administration of artificial UV-B (broad-band or narrow-band) and/ or UV-A radiation for 2–3 weeks prior to initial sun exposure Phototoxicity and ... initial sun exposure Phototoxicity and Photoallergy These photosensitivity disorders are related to the topical or systemic administration of drugs and other chemicals Both reactions require the ... excited-state photosensitizer that can transfer its absorbed energy to a bystander molecule or to molecular oxygen, thereby generating tissue-destructive chemical species, including ROS Phototoxicity...

Ngày tải lên: 07/07/2014, 01:20

... sensitive to UV-B, UV-A, and visible wavelengths Diagnostic confirmation of phototoxicity and photoallergy can often be obtained using phototest procedures In patients with suspected phototoxicity, ... drug photosensitivity involves first and foremost the elimination of exposure to the chemical agents responsible for the reaction and minimization of sun exposure The acute symptoms of phototoxicity ... energy, become photoexcited, generate ROS, and evoke cutaneous photosensitivity The mechanism of porphyrin photosensitization is known to be photodynamic, or oxygen-dependent, and is mediated by...

Ngày tải lên: 07/07/2014, 01:20

... eliminates exposure to porphyrinogenic agents Erythropoietic protoporphyria originates in the bone marrow and is due to a decrease in the mitochondrial enzyme ferrochelatase secondary to numerous gene ... Treatment of PCT consists of repeated phlebotomies to diminish the excessive hepatic iron stores and/ or intermittent low doses of the antimalarial drugs chloroquine and hydroxychloroquine Long-term remission ... erythrocyte protoporphyrin Detection of increased plasma protoporphyrin helps to differentiate lead poisoning and iron-deficiency anemia, in both of which elevated erythrocyte protoporphyrin levels...

Ngày tải lên: 07/07/2014, 01:20

... effects of long-term UV-B phototherapy and PUVA photochemotherapy mimic those seen in individuals with chronic sun exposure and include skin dryness, actinic keratoses, and an increased risk of skin ... important to educate parents and young children about the hazards of sunlight Simply eliminating exposure at midday will substantially reduce lifetime UV-B exposure Phototherapy and Photochemotherapy ... bases and eventually form DNA cross-links These structural changes are thought to decrease DNA synthesis and relate to the improvement that occurs in psoriasis The reason that PUVA photochemotherapy...

Ngày tải lên: 07/07/2014, 01:20

... including the face, the neck, and the hands Major risk factors include male sex, childhood sun exposures, older age, fair skin, and residence at latitudes closer to the equator Whites of darker complexions ... due to failure to control for confounding factors such as sunscreen stability and frequency of application Since no prospective studies are available to address this issue, it seems reasonable to ... help to explain the leathery texture and the blotchy discoloration of sun-damaged skin UV-A is important in the pathogenesis of photoaging in human skin, and ROS are likely involved The dermis and...

Ngày tải lên: 07/07/2014, 01:20

... very informative marker, linked totally to the QTL was assumed to exist, and the residual variance was assumed to be known (20 sires and 50 progeny per sire) The T and Ttests were simplified accordingly ... 3.84, and the X!oddl 95 % quantile, 31.41 ddl The main and quite strange result was that the power of T!is always larger than or equal to the power of the other tests In order to compare the T! and ... thresholds of the situation, and for a given number of sires and two tests appear to be very close to each other for all cases (data not shown), which is in agreement with the asymptotic in linear models...

Ngày tải lên: 09/08/2014, 18:21

... able to handle it, and when it’s not here, you have to be able to get real small We’re very seasonal.” DREAM SCHEMES • 13 How Tom Got Started Tom Doyle came to Charleston from New Jersey to study ... covering Charleston’s history, architecture, gardens, people, and points of interest “As opposed to a motorized tour, our drivers can turn and talk to the people and make eye contact,” Tom says “It’s ... you’re waiting for the carriage to fill up, you chat with the passengers To have a really great tour you need to get to know your customers And tourists are great to deal with because 99.9 percent...

Ngày tải lên: 31/03/2017, 10:34

... MATERIALS AND METHODS Fifteen trees were sampled in a 28-year-old experimental poplar plantation The stand belongs to the ONF Different cultural treatments have been applied to the stand In 1968 ... the stem (suppression of forks) and is expected to have an effect on tension wood and growth strain distribution However, this effect will not be analyzed here due to the limited sample size leaning ... positions and (opposite) of characteristic logs near strain measurements (figure 5a) and stored until they reached a final average equilibrium moisture content of 12% (storage for months at 20°C and...

Ngày tải lên: 08/08/2014, 19:21

... were inclined to use more efficient transport mode, such as cycling, to access the clinic The distribution of Tai Po District's residents was reflected by the mean centre and standard distance ... study has enabled us to explore the social and public health contexts of heroin dependence from two interrelating angles: distribution of methadone clients on one hand, and the utilization of ... minutes Overall, about half (55.6%) went to the clinic by walking and 30.2% by cycling, so they did not need to pay for their daily trip A minority (14.3%) had to pay for the transportation Using...

Ngày tải lên: 11/08/2014, 18:20

... healthy lambs to restock formerly scrapie-afflicted farms S), protein and energy The samples were sent to the Department of Animal and Land Resources at the Agricultural University of Iceland There ... was significantly higher in Areas I and VII than in Areas II, III, V and VI, and the difference between Area II on the one hand and Areas V and VI on the other was also significant There are ... them to the model as a fixed effect and restricting the analyses to those Areas where both categories were found together Page of 10 Results The results are presented in Figure 2, Tables and and...

Ngày tải lên: 12/08/2014, 18:22

... which is too narrow, and to a lesser extent this also applies to Swedes and some Norwegians The fall-rise tone is dif®cult for Scandinavian learners Norwegians (and some Swedes) tend to use too many ... leading to mistakes like *a books shop and *a ten-miles trip Students need to be told the difference between, for example, They'll all go to another university and They'll all go to other universities, ... branch of Indo-European, and as such is closely related to Frisian, English, German and the Scandinavian languages It is the standard language in the Netherlands and in Flanders, the northern part...

Ngày tải lên: 17/08/2013, 08:35

... introduction of these phytochemicals with low toxicity, which comply with health and environmental standards, as alternatives to methyl bromide and phosphine for the preservation of grain and dry food C7 ... activity against Sitophilus oryzae, Stegobium paniceum, Tribolium castaneum, and Callosobruchus chinensis (Deshpande et al., 1974; Deshpande and Tipnis, 1977) In our laboratory, in order to isolate active ... highly selective to insects, since they are probably targeted to the insect-selective octopaminergic receptor, a 398 E Shaaya and M Kostyukovsky Table 16.8 Toxicity of CS2 against stored-product...

Ngày tải lên: 25/10/2013, 05:20

... side effects and suggest ways to help you manage them Many skin cancers can be removed quickly and easily But some people may need supportive care to control pain and other symptoms, to relieve ... medicines and suggest other ways to help with these problems They usually go away when treatment ends You may want to read the NCI booklet Chemotherapy and You 28 You may want to ask your doctor these ... Diagnosis and staging • Treatment • Follow-up care • How to prevent another skin cancer from forming • How to a skin self- exam This booklet has lists of questions that you may want to ask your doctor...

Ngày tải lên: 14/02/2014, 22:20

... even know why I bother to try. And this town ­ it’s full of jerks. They’re too  dumb to appreciate real music, and they’re cheap, too ­ I only sold two CDs. And the club manager must think I’m a jerk, too. I’m sure he’ll never let me perform  ... even know why I bother to try. And this town­it’s full of jerks. They’re too dumb  to appreciate real music, and they’re cheap, too – I only sold two CDs. And the  club manager must think I’m a jerk, too. I’m sure he’ll never let me perform there  ... when they were teenagers or even younger, or for things that other people did to them And in many cases that I see, people’s shame and regret are keeping them  “frozen” and unable to make progress on their goals.  Shame, guilt, regret and remorse are toxic, and useless, emotions. The only ...

Ngày tải lên: 21/02/2014, 22:20

... counties, towns and villages which authorize payment for five years or less are not subject to mandatory or permissive referendum Similarly, city bond ordinances should not be subject to mandatory ... to cover this emerging topic pension obligation bonds and other post-employment benefits 27 chapter nine GASB 45 A Accounting Change OPEB refers to other post-employment benefits,” meaning other ... 45 purposes, and higher OPEB UAAL and ARC amounts due to an ability to apply a higher investment return assumption to the calculation of these amounts; and may become a ratings factor (for example,...

Ngày tải lên: 06/03/2014, 08:20

... write a response to material they have heard and read, and to compose  an essay in support of an opinion.   How to Teach TOEFL TOEIC IELTS and More    27    F. Practice Testing and recalibrating goals  ... It is also important that you speak clearly and answer each question  according to directions.    33      Free Resources from TOEIC:  TOEIC Listening and Reading  Sample Test (PDF)   How to Teach TOEFL TOEIC IELTS and More    34    The TOEIC Writing Test Format  ... you will assign as homework, and which you will skip.  How to Teach TOEFL TOEIC IELTS and More    48    Assigning Time  When deciding which textbook drills to use and how much time to allot  to them, keep their relative value in mind. ...

Ngày tải lên: 08/03/2014, 20:20