selected characteristics of the physical and human setting

... Research at the Intersection of the Physical and Life Sciences Research at the Intersection of the Physical and Life Sciences Committee on Research at the Intersection of the Physical and Life Sciences ... dedicated to the furtherance of science and technology and to their use for the general welfare Upon the authority of the charter granted to it by the Congress in 1863, the Academy has a mandate that ... constructed of a wide range of nonbiological materials However, the specific control of the shape and the osmotic properties when the number of components in the surface and interior of the membrane...

Ngày tải lên: 14/03/2014, 10:20

... (16.7%) .The difference was statistically significant with p < 0.01 3.1.2.4 .The structure of the lesions on US and CT Table 3.8 The structure of the lesion on US The structure of the lesions Number of ... fascioliasis on CT and MRI In 2006, Pham Thi Kim Ngan studied the imaging characteristics of fascioliasis lesions on US and CT 1.2 ADVANTAGES AND DISADVANTAGES OF THE RESEARCH 1.2.1 Advantages of the research: ... clustered and scattered in the liver parenchyma 3.1.2.5 The effects of lesions to the portal veins (PV) on US and CT Table 3.9 The effects of lesions to the PV US (n = 126) CT (n = 126) P Number of...

Ngày tải lên: 01/07/2016, 11:15

... interspersed by a stimulus which deviated from the standard in the intensity of the first component and the glide direction of the second constituent The number of distinct MMN components elicited by ... et al The relationship of age, gender, handedness, and sidedness to the size of the corpus callosum Academic Radiology 1994; 1:243-248 69 Driesen NR, Raz N The influence of sex, age, and handedness ... P300 and the N2b Data indicate that the P300 is involved not only in processes of working memory, but may interact with the N2b in the control of motor response to external cues Through the use of...

Ngày tải lên: 02/11/2012, 11:08

... Given that the roles of these residues definitely confirm each other, the difference in their significance might be attributable to the importance and ⁄ or necessity of the receipt of the phenol-hydroxyl ... environments of BPA in the ligand-binding pocket of the ERRc The proximity of each amino acid residue (within a ˚ distance of A) to BPA is shown in the boxes depicting the a-helices The portrait ... activity of BPA (1 and 10 lM) against the inverse agonist activity of 4-OHT (1 and 10 lM) The assay set marked with an asterisk shows the the inverse antagonist activity of BPA for lM 4-OHT, and the...

Ngày tải lên: 18/02/2014, 16:20

... affinity of Fpg for the THF:C ligand was 1.6-fold higher than for the THF:A ligand The presence of Mg2+ had little effect on the binding of Fpg to the THF:C ligand and slightly improved binding to the ... evaluate the effects of ionic strength and Mg2+ on the activity and specificity of OGG1, we measured the apparent values of k2 and k3 under conditions of low salt (KPi only) and no Mg2+, low salt and ... strength, the concentration of divalent cations such as Mg2+, the nature of the buffering agents, the presence of competing polyamines and other small molecules, and crowding by other macromolecules Their...

Ngày tải lên: 18/02/2014, 18:20

... Fragments of HSQC and HMBC spectra of compound Labels illustrate assignment of the amide linkage between the amino group of Asp and the carboxyl group of GalA residue E Scheme The structures of oligosaccharides ... monosaccharides present in the products and were identified, and the ratio of structures and was close to : All chemical shifts remained mostly unchanged with the exception of H/C-2 and H/C-3 of the glycerol ... because of the existence of branches in the molecule Similarly, the tandem MS was conducted for the doubly charged ion at m/z 1180.25 (data not shown) and the mass spectral data fully agree with the...

Ngày tải lên: 19/02/2014, 16:20

... compared to a human gold-standard Yet, the assessments of the two aspects were often the same—readability/fluency of the sentence is important for understanding the sentence Only after the assessor ... better understand which factors are predictive of good fluency The distribution of fluency scores in the dataset is rather skewed, with the majority of the sentences rated as being of average fluency ... with the idea that these are qualities of the translations that are independent of each other Fluency was judged directly by the assessors, while adequacy was meant to assess the content of the...

Ngày tải lên: 22/02/2014, 02:20

Ngày tải lên: 14/03/2014, 13:20

... introduced alanine at these two positions, with the aim of determining whether any of the observed effects were a result of changes in the size and charge of the amino acid at these positions Results ... the conformation of this loop Changes in the conformation of the backbone at this point and changes in the orientation of other side chains, as a result of the introduction of the large charged ... In view of the structural similarities between yeast and mammalian enolases and the high degree of sequence conservation, we believe that the effects of these mutations on the structure and function...

Ngày tải lên: 16/03/2014, 06:20

... around the ligand-binding site of liganded hemoglobin The conformation of Val(E11) in the a and b subunits relative to the heme plane is quite dependent on the nature of the anions and the pD of the ... yield of BR (the efficiency of the ligand escape) for the a and b subunits within the oxygenated tetramer and dimer of human hemoglobin were revealed As a consequence, the regulation of the affinity ... The time course and the yield of the geminate phase are both sensitive to the immediate environment of the heme, and to the dynamics of structural changes in the protein Hence, the analysis of...

Ngày tải lên: 16/03/2014, 14:20

... to lower volume fracturing of some tight gas and conventional reservoirs in the southern part of the North Sea and in onshore Germany, the Netherlands, Denmark and the UK Preliminary indications ... to the risk to the environment and human health of such operations in the EU An analysis of all EU 27 Member States’ legislation and standards was outside the scope of this study, as was the ... wells and other equipment throughout the development, operational and post-abandonment lifetime of the plant (well pad) so as to avoid the risk of surface and/ or groundwater contamination The challenge...

Ngày tải lên: 23/03/2014, 00:20

... mixing the human CPR FMN domain with its FAD/NADPH domain (% 16-fold) (29) However, the domain mixture still reconstituted only % 2% of the activity of the full length CPR In the case of NR1, the ... spectroelectrochemical titrations of the isolated FAD/NADPH and FMN domains of NR1 enabled the determination of the midpoint reduction potentials for the oxidized/semiquinone (E1) and semiquinone/hydroquinone ... FAD/NADPH domain and the oxidized FMN domain The lack of a second order dependence of the observed rate for interdomain electron transfer as the Ó FEBS 2003 Redox properties of human NR1 (Eur J...

Ngày tải lên: 23/03/2014, 21:20

... protein The docking of the QZ59 stereoisomers into the human P-gp model, and the subsequent analysis of the ligand interactions, confirms the possibility for multispecific interactions of the ligands ... and the surface of the binding site in the lower binding site (C) Closer view (from the bottom) of the protein–ligand interactions and the surface of the binding site in the upper binding site The ... size and intensity (the darker the color, the more exposed the residue) of the disks drawn behind some of the residues to denote the difference in their solvent exposure as a result of the presence...

Ngày tải lên: 29/03/2014, 22:21

... 0.0064 a Of the genes analyzed, the GO biological process is known for 739 up-regulated genes and 215 down-regulated genes Others are unknown b Of the genes in the mother population, the GO biological ... for 12 441 Others are unknown c The significance of the appearance of the GO term (biological process) in the up-regulated and down-regulated genes was calculated as a P value by the software GO ... that the majority of liver functions are detected in AT-MSC-Hepa, as well as in human hepatocytes and human liver Table Comparison of the number of genes up-regulateda in ATMSC-Hepa and human...

Ngày tải lên: 30/03/2014, 04:20

... [26] The ligand-binding affinity profile of the final purified preparation is similar to that of the original H1)10xHis receptor expressed in Sf9 cell membranes, and matches the affinity profile of the ... of their widespread physiological relevance, relatively little is known about structure and receptor–ligand interactions of the histamine receptors Elucidation of the structure and dynamics of ... On the one hand it is essential for purification, while on the other hand it destabilizes the receptor, resulting in a timedependent loss of functional properties The kinetics of this loss of...

Ngày tải lên: 30/03/2014, 14:20

... are hampered by the dearth of objective empirical data on health worker flows and behaviours, the determinants of their choices and the implications of these dynamics in terms of policy [20] Various ... in their birth region or the area where they studied However, the validity of these findings may be limited by the relatively small size of the subsamples used for each estimation and because the ... of areas where other research methods, such as qualitative tools, could be helpful in understanding the results of the DCEs better, and take the debate on the limitations and interpretation of...

Ngày tải lên: 18/06/2014, 17:20

Ngày tải lên: 18/06/2014, 18:20

... effect of depression on the mental aspect of QoL went through the mediator of pain, and over 72% of the effect was direct When depression was the mediator, depressive symptoms accentuated the negative ... effects of pain on physical QoL The indirect effect of depression on the pain-QoL link pathway was 0.08, indicating that about 75% of the effect of pain on QoL impacted through the mediator of depression, ... and 25% of the effect was direct Statistically, the mediation of depression (Model 4: 75%) exerted the strongest effect (cf Model 1: 28%) These findings offer insights to the current understanding...

Ngày tải lên: 18/06/2014, 19:20

Ngày tải lên: 18/06/2014, 19:20

... during pyrolysis • The extent of vapor dilution in the reactor • The time and temperature history of the vapors in the reactor • The time and temperature history of the vapors in the heated transfer ... volume” of the solute, solubility is predicted This is satisfied if the distance from the center of the solvent sphere to the center of the solute sphere (Rij) is smaller than the radius of the solute ... fines • The water content of the bio-oil • The extent of contamination of the bio-oil during storage by corrosion or leaching of the containers • Exposure to air during storage • The length of storage...

Ngày tải lên: 19/06/2014, 14:02