sclerosus lichen simplex chronicus and squamous cell hyperplasia

... information, see the section, “Can basal and squamous cell skin cancers be found early?” Can basal and squamous cell skin cancers be found early? Basal cell and squamous cell skin cancers can be found ... develop squamous cell skin cancer, especially on the lips Smoking is not a known risk factor for basal cell cancer Do we know what causes basal and squamous cell skin cancers? Most basal cell and squamous ... years Squamous cell carcinoma About out of 10 skin cancers are squamous cell carcinomas (also called squamous cell cancers) The cells in these cancers share features with the squamous cells seen...

Ngày tải lên: 22/03/2014, 16:21

... scheme of Schnitt and VincentSalomon [5], these lesions may be classified into four groups, that is, columnar cell change with and without atypia and columnar cell hyperplasia with and without atypia ... columnar cells (single arrow) and flat epithelial cells of the Within Within this single dilated duct is a portion lined by hyperplastic columnar cells (single arrow) and flat epithelial cells of ... between MLT and columnar cell hyperplasia given their coexistence and the morphologic transitions between these two lesions The proliferative indices of the columnar cell lesions and the MLT...

Ngày tải lên: 11/08/2014, 23:21

... epithelial cells into mucous cells and differentiation of proliferating cells to mucous cells [15,49] Therefore, the inflammatory mediators may cause epithelial cell proliferation and directly ... these cell types, may be contributing to epithelial cell hyperplasia and increased mucin synthesis and storage resulting in GCM It is established that IL-6, produced by both macrophages and neutrophils ... http://respiratory-research.com/content/8/1/24 Figure and goblet cell numbers reach maximum levels d post instillation of 1000 μg LPS Total cell Total cell and goblet cell numbers reach maximum levels d post...

Ngày tải lên: 12/08/2014, 15:20

... embryonic stem and germ cells [11,12] Recent data show that cells expressing high levels of Oct4 are present in breast cancer, bladder cancer and oral squamous cell carcinoma and are associated ... nucleus of tumor cells (A) High Oct4 expression in tumor cells, (B) low Oct4 expression in tumor cells, (C) high Sox2 expression in tumor cells, and (D) low Sox2 expression in tumor cells Ge et ... Oct-4 and Nanog in oral cancer stem-like cells and high-grade oral squamous cell carcinoma Clin Cancer Res 2008, 14:4085-4095 Ezeh UI, Turek PJ, Reijo RA, Clark AT: Human embryonic stem cell genes...

Ngày tải lên: 18/06/2014, 16:20

... development and cancer [16] EMT in cancer leads to the loss of cell- cell adhesion and cell polarity as well as altered cell- extracellular matrix interactions, resulting in invasion and metastasis ... and exert distinct biological actions in ESCC cells Methods Cell lines and cultures I) Five cell lines of human ESCC cells (OE21, TE5, TE8, TE10, and TE11), a non-malignant human esophageal squamous ... esophageal squamous cell carcinoma (ESCC) cell lines, OE21 (while bars) and TE10 (black bars), compared to the non-malignant esophageal squamous cell line, Het1A cells (A) On the other hand, miR-153,...

Ngày tải lên: 18/06/2014, 19:20

... contributions TJC and CHC conceived the study design, carried out and coordinated immunohistochemical examinations of tumor specimens and data analysis, and drafted the manuscript CYC and HTT participated ... intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer J Clin Oncol 2003, ... kinase and EGFR and then delayed the DNA repair [37-39] Oxaliplatin induced double-strand breaks [40] When cetuximab was combined with oxaliplatin, cetuximab reduced the expression of ERCC-1 and...

Ngày tải lên: 18/06/2014, 19:20

... tumour tissues and oesophageal squamous cell carcinoma cancer cell lines, and is related to clinical pathology and prognosis of the patients with oesophageal squamous cell carcinoma Cellular function ... grade Material and methods Cell lines and human oesophageal specimens This study used three human oesophageal squamous cell carcinoma cell lines and an oesophageal adenocarcinoma cell line Moderate-differentiated ... between MTSS1 expression and oesophageal squamous cell carcinoma patient clinical data in a cohort of human oesophageal squamous cell carcinoma specimens by using quantitative PCR and immunohistochemical...

Ngày tải lên: 18/06/2014, 19:20

... the three cell lines tested, MCF7 cells had high levels of Her3, BxPC3 cells had intermediate Her3, and A549 cells had low Her3 (Figure 1) We analyzed the expression pattern of Her2 and Her3 proteins ... contributions J-YC and SMH conceived of the study and devised the experimental design SMH and CM designed and build the tissuemicroarrays MT, J-YC, and YK performed experiments RX, HC, J-YC and SMH performed ... preferred partner, and requires Her3 to promote cell proliferation As Her3 and Her2 are mutually dependent proteins and function in complementary manner, but the combination of Her2 and Her3 expressions...

Ngày tải lên: 18/06/2014, 22:20

... and GL provided study materials or patients HSB, PS, JG, AB, CW and GL participated in collection and assembly of data CP and AS participated in data analysis and interpretation CB, HSB, AB and ... tumor cells binds to TLR4 on dendritic cells and is required for cross-presentation of tumor antigens and a subsequent effective anti-tumor immune response This effect was impaired in HeLa cells ... polymorphisms Asp299Gly and Thr399Ile in head and neck squamous cell carcinomas Journal of Translational Medicine 2011 9:139 Page of Submit your next manuscript to BioMed Central and take full advantage...

Ngày tải lên: 18/06/2014, 22:20

... contributions TJC and CHC conceived the study design, carried out and coordinated immunohistochemical examinations of tumor specimens and data analysis, and drafted the manuscript CYC and HTT participated ... intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer J Clin Oncol 2003, ... kinase and EGFR and then delayed the DNA repair [37-39] Oxaliplatin induced double-strand breaks [40] When cetuximab was combined with oxaliplatin, cetuximab reduced the expression of ERCC-1 and...

Ngày tải lên: 20/06/2014, 03:20

... tumour tissues and oesophageal squamous cell carcinoma cancer cell lines, and is related to clinical pathology and prognosis of the patients with oesophageal squamous cell carcinoma Cellular function ... grade Material and methods Cell lines and human oesophageal specimens This study used three human oesophageal squamous cell carcinoma cell lines and an oesophageal adenocarcinoma cell line Moderate-differentiated ... between MTSS1 expression and oesophageal squamous cell carcinoma patient clinical data in a cohort of human oesophageal squamous cell carcinoma specimens by using quantitative PCR and immunohistochemical...

Ngày tải lên: 20/06/2014, 04:20

... the three cell lines tested, MCF7 cells had high levels of Her3, BxPC3 cells had intermediate Her3, and A549 cells had low Her3 (Figure 1) We analyzed the expression pattern of Her2 and Her3 proteins ... contributions J-YC and SMH conceived of the study and devised the experimental design SMH and CM designed and build the tissuemicroarrays MT, J-YC, and YK performed experiments RX, HC, J-YC and SMH performed ... preferred partner, and requires Her3 to promote cell proliferation As Her3 and Her2 are mutually dependent proteins and function in complementary manner, but the combination of Her2 and Her3 expressions...

Ngày tải lên: 20/06/2014, 04:20

... and GL provided study materials or patients HSB, PS, JG, AB, CW and GL participated in collection and assembly of data CP and AS participated in data analysis and interpretation CB, HSB, AB and ... tumor cells binds to TLR4 on dendritic cells and is required for cross-presentation of tumor antigens and a subsequent effective anti-tumor immune response This effect was impaired in HeLa cells ... polymorphisms Asp299Gly and Thr399Ile in head and neck squamous cell carcinomas Journal of Translational Medicine 2011 9:139 Page of Submit your next manuscript to BioMed Central and take full advantage...

Ngày tải lên: 20/06/2014, 04:20

... Med Sci 2008, of squamous cell cervical carcinomas FIGO stage IB, respectively This is in line with our previous study identifying EphA2 and EphrinA-1 in 88% and 92% of squamous cell cervical carcinomas ... cells were positive for p21, cyclin E and cyclin D3 and ≥50% of tumor cells were positive for p27, p16 and cyclin A [28, 29] Table 5-years disease-free and disease-specific survival Variables ... EphA2 and EphrinA-1 was present in 40% and 60% of normal squamous epithelium, respectively The positive overall staining (weak/moderate/strong) of EphA2 and EphrinA-1 was observed in 90% and 85%...

Ngày tải lên: 08/08/2014, 17:20

... dystrophic epidermolysis bullosa and squamous cell carcinoma Arch Dermatol 2005, 141:110-111 36 Marks R: Squamous cell carcinoma Lancet 1996, 347:735-738 37 Cook MG, Green MA, Anderson B, Eggermont AM, ... collection and data analysis, reviewed the literature, and wrote the manuscript ZD provided the pathology figures and legends PW wrote the manuscript and supervised the work All authors read and approved ... E, Pagan M, Concolino F, Ruatti P: Lymphatic mapping and sentinel node identification in squamous cell carcinoma and melanoma of the head and neck Tumori 2002, 88:S39-41 29 Tartaglione G, Potenza...

Ngày tải lên: 09/08/2014, 02:20

... correlated with nodal involvement, stage and size of the tumor, and survival Sensitivity and specificity were calculated Data were processed by Microsoft Excel and SPSS for descriptive statistic values, ... metastasizing of lymphatic vessel invasion (L1) using the conventional and immunohistochemical method in squamous cell carcinomas (SCC) of larynx and hypopharynx The used antibody D2-40 (podoplanin) recognizes ... diameter was investigated For standard staining and immunohistochemistry serially prepared sections were examined In large tumors, especially areas of the lateral and deep tumor borders (front...

Ngày tải lên: 09/08/2014, 04:21

... head and neck skin squamous cell carcinomas that present a higher incidence of lymph node addressed by several studies [7-9], trunk and extremities tumors usually not present metastasis and the ... involving the parotid gland Head Neck 2001, 23:744-748 Joseph MG, Zulueta WP, Kennedy PJ: Squamous Cell Carcinoma of the skin of the trunk and limbs: The incidence of metastases and their outcome Aust ... extremity (shoulder, arm and forearm), 7; lower extremity (thigh and leg) 16; hand 12 and foot The T classification was T3 in 36 cases and T4 in 21 cases 11 patients initially presented with lymph...

Ngày tải lên: 09/08/2014, 07:21

... examination of squamous cell carcinoma Microscopic examination of squamous cell carcinoma A) Esophagus infiltrative squamous cell carcinoma (H and E 10×); B) Esophagus infiltrative squamous cell carcinoma ... B) The immunohistochemistry of the fused cells showed an intense and diffuse positivity for CD117, CD34 and CD99 and negative results for S100, desmin and actin (Figure 3A, B) The proliferate ... in its design and coordination and helped to draft the manuscript All authors read and approved the final manuscript References Esophageal GISTs are rarely described in literature, and no cases...

Ngày tải lên: 09/08/2014, 07:22

... patients had histologically confirmed squamous cell carcinoma Histological grading was recorded in 134 patients and 76 (50.3%) had poorly differentiated squamous cell carcinoma Stage distribution ... entire cohort of 151 patients the OS rates were 67.5% and 58.3%; the CSS rates were 75.1% and 66.8% and PFS rates were 72.5% and 67.2% at and 3-years respectively Survival rates Median follow ... parotid-sparing 3D-CRT or IMRT and of the 21 LRR, 17 were in-field and were marginal [18] Studer et al reported a 80% and 87% local and regional control rate, respectively and 95% of failures occurred...

Ngày tải lên: 09/08/2014, 09:20