... tissue and gastrointestinal tract, as well as other sites, are known to reach the CNS to effect changes in feeding behavior and energy expenditure Thus, insulin, leptin and ghrelin, as well as other ... maintaining a lower food intake This is accompanied by a suppression in energy expenditure These data suggest that CPT1c can integrate carbohydrate and lipid nutrient sensing in the brain and ... increase in malonyl-CoA promotes a decrease in neuropeptide Y and agouti related peptide in hypothalamic malonyl-CoA while promoting an increase in proopiomelanocortin and cocaine and amphetamine...
Ngày tải lên: 14/02/2014, 22:20
... molecules, including cyclins, cyclin-dependent kinases, their inhibitors and the retinoblastoma protein (RB), as well as E2Fs E2F and RB family members appear to participate in the regulation of ... cyclin ⁄ cyclin-dependent kinase holoenzymes, releasing the E2F complex and thereby resulting in activation of the E2F target genes [9] Fajas et al [10] demonstrated that the E2F protein 566 family ... inhibitors include two families of proteins, the Cip (Kip) family and Ink4 family, and are central players in the exit of cells from the cell cycle [11] Loss of p27Kip1 or p21Cip1 in mice leads...
Ngày tải lên: 06/03/2014, 01:20
Báo cáo y học: "The opposite effects of fluvoxamine and sertraline in the treatment of psychotic major depression: a case report" potx
... fluvoxamine binds to sigma-1 receptors in the intact human brain at therapeutic doses [25], suggesting that sigma-1 receptors are involved in the active mechanisms of fluvoxamine [19] Interestingly, ... and TK contributed to the clinical and rating evaluations during the follow-up periods KH conceived of the study and participated in its study and coordination All authors read and approved the ... stopped Treatment with fluvoxamine (150 mg) monotherapy was maintained, and her condition remained good At years after the disappearance of the delusions, the patient began overeating and oversleeping,...
Ngày tải lên: 08/08/2014, 23:21
Báo cáo y học: " Comparison of the efficacy of lamivudine and telbivudine in the treatment of chronic hepatitis B: a systematic review" pdf
... approved the final manuscript Competing interests The funding source had no influence on study design, in the collection, analysis, and interpretation of the data, in the writing of the manuscript, ... telbivudine are more widely used in treatment of CHB In this systematic review, we focus on the comparison of the efficay of lamivudine and telbivudine in the Figure Effect of telbivudine vs lamivudine ... of the healthcare system is not satisfactory There are limitations in the reimbursement of anti-HBV therapy, either in the selection of agent or the duration of dosing Therefore, lamivudine and...
Ngày tải lên: 12/08/2014, 01:21
Báo cáo y học: "Formulas Vasopressin and epinephrine in the treatment of cardiac arrest: an experimental study" docx
... effect of the combination of the two drugs in comparison to epinephrine alone in the first minute of CPR with an increase of CPP This increase was further attenuated in the second minute when ... that the combination of epinephrine and vasopressin in the treatment of VF cardiac arrest improved perfusion pressures and short-term survival, in comparison to the single use of epinephrine This ... evidence to the existing literature of the epinephrine-vasopressin combination benefits and further evaluation of these results should be undertaken in the future Key messages • The combination of...
Ngày tải lên: 13/08/2014, 08:21
Báo cáo y học: "Special considerations in the treatment of patients with bipolar disorder and medical co-morbidities"
... (Tegretal and others), clozapine (Clozaril), droperidol (Inapsine and others), gabapentin (Neurontin), haloperidol (Haldol and others), lamotrigine (Lamictal), lithium (Eskalith and others), metformin ... pre-dialysis and 2–3 hrs following the post-dialysis dose There is a case report in which lithium levels were maintained in the therapeutic range by intraperitoneal administration of lithium during continuous ... portacaval shunting, thereby decreasing first pass metabolism; decrease in quantities and affinity of plasma proteins, thereby increasing free-drug levels; increase in volume of distribution in patients...
Ngày tải lên: 25/10/2012, 10:51
Báo cáo y học: " Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial"
... glucosamine and chondroitin, one month prior to study and during the study, other than multivitamin and mineral supplements containing vitamins and minerals as the sole medicinal ingredients Use of ... Subjects in the UC-II group were instructed to take two “sugar pills” in the morning to protect blinding and two UC-II capsules in the evening accounting for a daily dose of 40 mg UC-II containing ... arthritis or other types of pain) or is unwilling to stop taking other medications for the treatment of OA Any other condition that, in the opinion of the investigator, would adversely affect the subject's...
Ngày tải lên: 26/10/2012, 09:48
Organizing pairwork and groupwork in the context of high school classrooms at pham van nghi upper secondary school, nam dinh province: A case study
... use their mother tongue in the first few lessons and then try to stop them overusing it One method is to explain briefly in English, then if necessary supply written instructions in their mother ... work and group work in language classes 50% of them saw the benefits of these activities in making class more interesting and 50% consider pairwork and groupwork helping in motivating students and ... the same view as in option 3, the teachers in this school thought that pair work and group work is the most useful for teaching grammar and speaking (100%), and then reading, writing, listening…...
Ngày tải lên: 07/11/2012, 14:54
The Use of Mushroom Glucans and Proteoglycans in Cancer Treatment potx
... main chains and 1-4 branchings, and the more common 1-3 main chains and 1-6 branchings.18 This fraction also is highly active in vitro and in animal models of cancer, although activity in these ... hospitals in Shanghai, Beijing, and other areas in China, with a total 189 patients The double-blind study used the same doses and test materials as the previous study, and examined PSP against the ... nonetheless, the findings are marked and support the use of PSK in breast cancer In 1992, a large randomized trial evaluated tamoxifen as an addition to the then-conventional chemotherapy, and...
Ngày tải lên: 06/03/2014, 02:21
Leaders and Leadership in the School, College and University
... what the schools need On the other side of the coin there are certain aspects of personnel and law and things of that nature where the LEA ought to be guiding the schools We try to involve the ... planning and recording books - in those there's the whole termly planning, the weekly planning and then the assessment as well (Assessment of what they've done?) Yes, there's all sorts of things in ... discussed in the final chapters In producing these Janet Ouston in 'Pathways to headship and principalship', Viv Garrett in 'Principals and headteachers as leading professionals' and Hugh Busher in...
Ngày tải lên: 18/03/2014, 11:58
WORMS: IDENTIFYING IMPACTS ON EDUCATION AND HEALTH IN THE PRESENCE OF TREATMENT EXTERNALITIES ppt
... receiving treatment in 2001 Thus in 1998, Group schools were treatment schools, while Group and Group schools were comparison schools, and in 1999, Group and Group schools were treatment schools and ... attending primary school within a certain distance from the school, the number of these attending schools assigned to treatment is exogenous and random Since any independent effect of local school ... old and all boys (the T pupils eligible for deworming in the treatment schools) as the school population (Ndit and Ndit ) for all schools in the remainder of the paper Measurement error in GPS...
Ngày tải lên: 22/03/2014, 15:20
Báo cáo khoa học: Genomic structure and expression analysis of the RNase j family ortholog gene in the insect Ceratitis capitata pptx
... isoforms The rectangles represent the exons and the horizontal bold lines the introns The black parts of the rectangles show the protein-coding region, the white parts represent the non-coding regions ... (SpuUn_WGA56223_2:75333–76952) and Nematostella vectensis (NW_001834409:c1450413–1449631) The numbers above the boxes indicate the size of the exons, and those below the lines indicate the size of the introns (B) ... into the pCR 2.1 cloning vector Three clones were selected, and their authenticity was verified initially by restriction endonuclease mapping and then by DNA sequencing in both directions Northern...
Ngày tải lên: 23/03/2014, 06:20
STRENGTHENING HEALTH AND FAMILY LIFE EDUCATION IN THE REGION doc
... STRENGTHENING HEALTH AND FAMILY LIFE EDUCATION IN THE REGION Teaching Methods The Common Curriculum emphasized the use of interactive teaching methods, and these were reinforced in training held by the ... implemented during the 2007/2008 school year Thus, the Common Curriculum was introduced in stages Each year, teachers in the intervention schools were offered training on the new Self and Interpersonal ... implemented during the 2007–2008 school year Thus, the Common Curriculum was introduced in stages Each year, teachers in the intervention schools were offered training on the new Self and Interpersonal...
Ngày tải lên: 28/03/2014, 20:20
Báo cáo hóa học: " Validation of the Korean version of the pediatric quality of life inventory™ 4.0 (PedsQL™) generic core scales in school children and adolescents using the rasch model" ppt
... properties of the Korean translation of the PedsQL™ 4.0 Generic Core Scales in school children and adolescents ages 8–18 Like in the school study with the original U.S English instrument [3] and other ... plans and school health clinics, identifying health disparities, promoting policies and legislation related to school health, and aiding in the allocation of health care resources [46] On the other ... the instructions ask how much of a problem each item has been during the past month In other words, the interaction between sample characteristics and the focus on "problems" in the items and instructions...
Ngày tải lên: 18/06/2014, 22:20
báo cáo hóa học:" Granuloma debridement and the use of an injectable calcium phosphate bone cement in the treatment of osteolysis in an uncemented total knee replacement" doc
... years later In January 2005 the patient began to develop similar medial pain and swelling in the left knee A bone scan showed increased activity in the medial femoral condyle indicating possible ... screening including erythrocyte sedimenta- Page of tion rate and C-reactive protein was normal Plain radiographs revealed areas of periprosthetic osteolysis in the femur and the tibia, and a ... with a resolution of the knee swelling and pain by months He remained symptom-free until 2008, when he began developing medial pain in the left knee and difficulty weight-bearing His Knee Society...
Ngày tải lên: 20/06/2014, 04:20
báo cáo hóa học:" Effects of GnRH agonist treatment on steroidogenesis and folliculogenesis in the ovary of cyclic mice" pot
... data interpretation and writing of the manuscript, AK helped in planning and supervised the work, participated in data analysis and interpretation Both the authors have read and approved the final ... caspase-3 and cleaved PARP proteins noticed in the mice treated in vivo with GnRH-Ag also showed increase in the number of atretic follicles in the ovary In an earlier study in rat, GnRH treatment, in ... receptors, and steroidogenic and apoptotic factors in the ovary was investigated following in vivo and in vitro administration of GnRH agonist in the intact cyclic mice Methods Animals All the experiments...
Ngày tải lên: 20/06/2014, 07:20