safety assessment of veterinary vaccines

... food animals R.C Parker 15 Safety assessment of veterinary vaccines M.J Francis 25 Surveillance for veterinary residues K.N Woodward 16 Microbiological assessment of veterinary medicinal products ... the principles of epidemiology to drug safety, can be seen as the completion of the safety evaluation of a drug that was started before the product was authorised Elements of veterinary pharmacovigilance ... terms of a marketing authorisation conducted with the aim of identifying and investigating a safety hazard relating to an authorised veterinary medicinal product • Off-label use: off-label use of...

Ngày tải lên: 06/03/2014, 16:20

... fluids, (3) lack of homology of CP4 EPSPS proteins with known protein toxins and (4) lack of allergenic potential of CP4 EPSPS proteins These data support the assessment of safety of the CP4 EPSPS ... and environmental safety assessments confirm the safety of this product The analyses included: 1) detailed molecular characterization of the introduced DNA; 2) safety assessments of the expressed ... conclusions of human and animal health safety of corn event NK603 and the nutritional equivalence of corn event NK603 to conventional corn varieties Environmental Assessment Environmental assessment of...

Ngày tải lên: 01/07/2014, 18:01

... limit of detection of IL-6 is 0.70 pg/ml LTC-4 (leukotriene) levels were determined by a leukotriene C4 EIA kit (Cayman Chemical; Ann Arbor, MI) The limit of detection of LTC4 is 10 pg/ml LTC4 of ... shortness of breath of an acute inhalation of saline or terbutalline: variability and sensitivity of a visual analogue scale in patients with asthma or COPD Eur Respir J 1992, 5:1043-1053 Bijl-Hofland ... composition of airway inflammatory cells Safety in human volunteers Table shows the baseline characteristics of the ten subjects who underwent graded exposure to aerosolized xylitol as a part of the...

Ngày tải lên: 12/08/2014, 18:21

... Svoboda P, Selbert A, Olthoff D, Nogare AD, Postier R, Hempelmann G, Butler T, Martin E, Zwingelstein C, Percell S, Shu V, Leighton A, Creasey AA: Assessment of the safety of recombinant tissue factor ... procedures accounted for 39.2% (58/148) of the total number of events (Table 5) The incidence of serious bleeding events was highest during the first day of therapy and decreased thereafter for ... observation that the concentration of drotrecogin alfa (activated) in plasma is below the assay level of detection in a large majority of patients within hours of discontinuing the infusion [11]...

Ngày tải lên: 12/08/2014, 19:22

... PROBABILISTIC ASSESSMENT OF THE SAFETY OF NAMDINH SEA DIKES 106 6.1 INTRODUCTION 106 6.2 GENERAL BACKGROUND OF PROBABILISTIC CALCULATION .108 6.3 PROBABILISTIC ASSESSMENT OF THE SAFETY ... Deterministic assessment of safety of the sea dike system in Namdinh province by applying the sea dike Design Standards of Vietnam and the Netherlands The safety assessment will be done by investigation of ... safety of the dikes system In this study the level II of probabilistic calculation is applied for safety assessment of one representative cross section of the dikes 1.4 Aims of study The aim of this...

Ngày tải lên: 03/10/2014, 13:14

... UNCERTAINTY AND IMPRECISION IN SAFETY ASSESSMENT OF OFFSHORE STRUCTURES ZHANG MINGQIANG (B.Eng., Tongji Univ.) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF CIVIL & ENVIRONMENTAL ... point for a reliable safety assessment of existing offshore structures, which is essentially the motivation for this thesis Among the various views of the safety assessment of an aging offshore ... and an adequate processing of the available information regarding marine corrosion and marine growth effects through the safety assessment of offshore structures In view of an appropriate mathematical...

Ngày tải lên: 10/09/2015, 08:39

... VII TABLE OF CONTENTS ACKNOWLEDGEMENTS I LIST OF PUBLICATIONS II LIST OF POSTER PRESENTATIONS III LIST OF ABBREVIATIONS V TABLE OF CONTENTS VIII SUMMARY XII LIST OF TABLES XV LIST OF FIGURES ... deuterated chloroform Figure 5.9 DEPT spectrum of unknown compound in deuterated chloroform Figure 5.10 HMQC spectrum of unknown compound in deuterated chloroform Figure 5.11 HMBC spectrum of unknown ... deuterated chloroform Figure 5.12 H-1H COSY spectrum of unknown compound in deuterated chloroform Figure 5.13 FTIR spectrum of unknown compound XVII Chapter Introduction 1.1 Quality and safety of herbal...

Ngày tải lên: 13/10/2015, 15:55

... of patient safety activities related to the initiative Assessment of contributions by AHRQ-funded patient safety projects to patient safety knowledge and patient safety practices Assessment of ... to strengthen patient safety practices Assessment of dissemination of new knowledge to stakeholders in the field Assessment of progress in adoption of effective patient safety practices Product ... identification of potential outcome measures and data sources Development of data sources when feasible Documentation of baseline trends for selected measures Assessment of impacts of the patient safety...

Ngày tải lên: 18/02/2014, 01:20

... Assessment of contributions by AHRQ-funded patient safety projects to patient safety knowledge and patient safety practices Assessment of other mechanisms used by AHRQ to strengthen patient safety ... practices Assessment of dissemination of new knowledge to stakeholders in the field Assessment of progress in adoption of effective patient safety practices Product Evaluation Initial identification of ... promote the adoption of other kinds of health IT in a variety of health care settings AVAILABILITY OF PATIENT SAFETY MEASURES The absence of a comprehensive set of national patient safety outcome measures...

Ngày tải lên: 15/03/2014, 22:20

... with coverage of 87.5% for the distance of 21 was 15.4 Gy: 87.5% of the doses in the isocenters of the micrometastases with a dis- Figure Boxplot of the dose at the 3D isocenter of each micrometastasis ... lower rate of local tumor recurrences in patients resected with a safety Page of margin > cm margin [9,12] In a study of Wray et al in 112 patients undergoing liver resection with a safety margin ... coverage of 87.5% and 75% 87.5% means that 87.5% of the data (dose measured in the center of the micrometastasis) are below the upper limit of the tolerance interval (with a confidence of 97.5%)...

Ngày tải lên: 09/08/2014, 08:23

... authors thank Professors William Brett and Jim Hughes of the Department of Life sciences and Tista Page of 11 (page number not for citation purposes) Journal of Immune Based Therapies and Vaccines 2006, ... effects on the production of anti-DNA Abs No signs of glomerulonephritis in phytol-treated mice Further evaluation of safety and toxicity was assessed by histopathology of the kidneys from mice ... Page of 11 (page number not for citation purposes) Journal of Immune Based Therapies and Vaccines 2006, 4:6 O.D @ 490nm PBS CFA/IFA Phytol PHIS-01 IgG1 IgG3 IgG2a IgG2b IgG Isotype Assessment of...

Ngày tải lên: 11/08/2014, 10:23

Ngày tải lên: 11/08/2014, 10:23

Ngày tải lên: 23/09/2012, 16:00

... in three out of four ambulance records and in nine out of ten air ambulance records Similarly, the Office of the Auditor General of Norway reviewed 14 EMCCs and found documentation of patient encounter ... terms of its usefulness for trauma research, we assessed the documentation rate of exact values and of RTS categories (0 - 4) of GCS score, RR, and SBP We found that a considerable fraction of ambulance ... precise documentation of physiologic data and more frequent documentation of repeated assessments Mechanistic descriptions of the motor vehicle accident were documented in 80 - 92% of ambulance records,...

Ngày tải lên: 25/10/2012, 09:56

... consequences of infection can be very severe, while the risk of living with one’s beloved cat is practically nill References Angulo FJ, Glaser CA, Juranek DD et al Caring for pets of immunocompromised ... Dis.1994;18:14-24 Han K, Shin DW, Lee TY, et al Seroprevalence of Toxoplasma gondii infection and risk factors associated with seropositivity of pregnant women in Korea J Parasitol 2008; 94: 963-965 ... 963-965 Grant S and Olsen CW Preventing zoonotic diseases in immunocompromised persons: the role of physicians and veterinarians Emerg Infect Dis 1999; 5: 159-163 http://www.medsci.org ...

Ngày tải lên: 03/11/2012, 11:06

... different group from others iii Table of Contents Chapter Title Page i Acknowledgement Abstract Table of Contents List of Figures List of Tables List of Acronyms List of Appendix ii iii iv viii ix x ... aware of all are there Another type of decision is one in which people are unsure of the importance of their criteria In this case to sharpen their knowledge of the criteria a wide selection of ... dependence of the priority of elements on the priority and number of other elements The principle of comparative judgments is applied to construct pair-wise comparisons of the relative importance of...

Ngày tải lên: 23/04/2013, 10:29

... is the assessment of listening different from the assessment of reading?? How is it similar?? Micro-skills for Listening • • • • • • • • • • • discriminate among the distinctive sounds of English ... Speech types (dialogues, monologues) • Mode of listening: audio, video, reader • Varieties of English • Scripted or unscripted • Length of listening, number of exchanges in dialogues Paraphrase Recognition ... questions Don’t expect full comprehension Consider integrating skills in the types of questions: discrimination of phonemes, paraphrase recognition, short answers, cloze, dictation, information...

Ngày tải lên: 18/08/2013, 17:10

... contributes 19.4% to 29.1% of the annual revenue of Palangkaraya reported by Meguri, et al., 2006, however it is a major source of water pollution The primary pollution of the river associated with ... Kalimantan It has four tributaries, one of which is the Rungan (about 82 km of long) (Statistic of Gunung Mas Regency, 2005) The Kahayan drains through the city of Palangkaraya to the Java Sea It ... Health Minister of Indonesia, 2002) The highest of mercury concentrations at st 403 is related to the location of the sampling point, where is located close to high activity of gold mining Total...

Ngày tải lên: 05/09/2013, 09:38

... Consequently, human risk assessment for MPP must be done on the basis of the contributions of its oxides The stability of MPP oxon sulfone with CYP3A4 was examined next The concentration of MPP oxon sulfone ... 50 60 Incubation time (min) Fig - Formation of MPP metabolites by CYP3A4 up to an incubation time of 60 The molarity of MPP (10 M) at the beginning of the reaction was defined as 100% - 218 - ... for 10 Among the metabolites of MPP, we focused on the formation of oxon metabolites, which are known inhibitors of cholinesterase activity The conversion rates of MPP to MPP oxon, MPP oxon sulfoxide...

Ngày tải lên: 05/09/2013, 10:15