... Properties of the iron-binding site of the N-terminal lobe of human and bovine lactotransferrins. Importance of the glycan moiety and of the non-covalent interactions between the N- and C-terminal ... Location of nucleolin-binding sites in both lobes, but not in the basic N-terminus of lactoferrin. (A) Schematic linear representation of the human lactoferrin (hLf) derivatives used in binding competition ... nucleolin that constitutes the binding site for ligands of nucleolin, such as HB-19 [26], midkine [19] and Lf (the results herein). In view of their efficient binding to surface nucleo- lin and to their...
Ngày tải lên: 07/03/2014, 15:20
Ngày tải lên: 23/03/2014, 10:20
INVESTIGATING DIVERSITY IN THE BANKING SECTOR IN EUROPE: THE PERFORMANCE AND ROLE OF SAVINGS BANKS pdf
Ngày tải lên: 29/03/2014, 07:20
creating emotion in games the craft and art of emotioneering
Ngày tải lên: 04/06/2014, 12:01
báo cáo sinh học:" Human resources for health at the district level in Indonesia: the smoke and mirrors of decentralization" ppt
Ngày tải lên: 18/06/2014, 17:20
do you believe in magic the sense and nonsense of alternative medicine
Ngày tải lên: 04/07/2014, 15:28
Báo cáo y học: "Management of chest pain: exploring the views and experiences of chiropractors and medical practitioners in a focus group interview"
... a role in managing chest pain from the point of entry, they must acquire and demonstrate competence in diagnosing the complaint. Chest pain can have a multitude of etiologies, involves an inherently ... set of themes as reached via consensus. This process involved examining themes for commonal- ity, classifying them for uniformity, and then reaching agreement on the final list of six key themes. ... for chest pain will depend on the nature of the condition and the urgency of the situation, that the point of referral may depend on the familiarity or relationship between the providers, and that the...
Ngày tải lên: 25/10/2012, 10:06
A study on cultural obstacles to the teaching and learning of speaking skills in the classroom of grade 10 at nguyen tat thanh high school
Ngày tải lên: 07/09/2013, 13:00
The Retinoblastoma Gene Family in Cell Cycle Regulation and Suppression of Tumorigenesis
... phosphorylation of these sites are involved in the regulation of p130 specific functions and interactions. The difference in phosphorylation sites and kinases involved in the phosophorylation of these sites ... expression of an E2F variant containing the DNA binding motif but not the pRb-binding or transactivation domain or introduction of a competitor plasmid containing multiple E2F binding sites, preventing ... modifications of pRb, p107 and p130. Within the Rb protein family p107 and p130 share the highest degree of homology (indicated by shaded areas). Within the pocket domain (pocket subdomains A and B and the...
Ngày tải lên: 25/10/2013, 21:20
Development of a Regional Risk Management Framework for APEC Economies for use in the Control and Prevention of Introduced Marine Pests
... Framework Conclusions, including the results of the November 2001 Workshop Management Framework - Introd uced Marine Pests Management capabilities and approaches APEC and the MRCWG have a role in liaising ... Pests Background Within APEC little is known on the introduction of marine pests Little practical information on measures to prevent introductions Lack of knowledge in what individual countries are doing Need ... NACA to enhance the effectiveness of existing instruments within APEC Institutional arrangements for managing the marine environment is fragmented in most economies Baseline surveys to...
Ngày tải lên: 28/10/2013, 11:15
Đo kiểm đánh giá can nhiễu mạng truyền hình cáp The Measurement and Analysis of the effect of interference in Television Cable network
Ngày tải lên: 26/11/2013, 20:44
Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx
... v-KIND KIND2 binding resides within residues 702–744 of MAP2. Residues 456–487 in the KIND2 domain of v-KIND contain the core MAP2 binding module To identify the core MAP2-binding site within the KIND2 ... specific MAP2 binding resides within the 32 residues (amino acids 456–487) of the v-KIND KIND2 domain. To examine whether the MAP2 binding core site of v-KIND binds to intact MAP2 protein, we coex- pressed ... under- stood, the data obtained in the present study indicate that the 43 residues (amino acids 702–744 in mice) that reside in the middle region of the CD act as the v-KIND binding core. The v-KIND-binding...
Ngày tải lên: 14/02/2014, 19:20
Tài liệu The Role of BCG Vaccine in the Prevention and Control of Tuberculosis in the United States: A Joint Statement by the Advisory Council for the Elimination of Tuberculosis and the Advisory Committee on Immunization Practices docx
... ). The renewed interest in examining the indications for BCG vaccination in the United States included consideration of the wide range of vaccine efficacies deter- mined by clinical trials and ... to explore the sources of the heterogeneity in the efficacy of the BCG vaccine reported in the individual studies. Using a model that included the geographic latitude of the study site and the data ... resurgence in the incidence of TB occurred in the United States and included increases in the number of TB cases among adults and children and outbreaks of multidrug-resistant TB (MDR-TB) involving...
Ngày tải lên: 15/02/2014, 13:20
Tài liệu Cleaner Water in China? The Implications of the Amendments to China’s Law on the Prevention and Control of Water Pollution pptx
Ngày tải lên: 18/02/2014, 04:20
Tài liệu Global action plan to control the spread and impact of antimicrobial resistance in Neisseria gonorrho pdf
... retraining of health-care providers and laboratory technicians • producing and disseminating standards for performing N.gonorrhoeae culture and AMR testing • working with WHO collaborating ... facility needs clear information for preventing reinfection, and counselling on the risks of infection, ways of 1. Test -of- cure is the reculturing or isolation and identification of the pathogen, ... strengthen their channels of communication with each other, as well as engaging with international and national media to highlight the issue of STIs in general and AMR in particular. Some of the...
Ngày tải lên: 18/02/2014, 15:20
Tài liệu Báo cáo khóa học: Mutations in the hydrophobic core and in the protein–RNA interface affect the packing and stability of icosahedral viruses doc
... hydrophobic core (M88V) and the other in the protein–RNA interaction (T45S), decrease the stability of the capsid. Our findings illuminate the role of packing in the icosahedral lattice of the virus capsid. Experimental ... different from those of other simple icosahedral viruses [13]. The main chain of the protein subunit folds into a five stranded antiparallel b-sheet (strands bC–bG) facing the interior of the phage particle, ... assembly of an icosahedral virus is encoded in the native conformation of the capsid protein and in its interaction with the nucleic acid. Here we investigated how the packing and stability of virus capsids...
Ngày tải lên: 19/02/2014, 12:20