role of the royal signals
Tài liệu Báo cáo khoa học: Role of the cag-pathogenicity island encoded type IV secretion system in Helicobacter pylori pathogenesis pptx
Ngày tải lên :
14/02/2014, 19:20
... infection [30]. These data were also
supported by several other research groups [15].
However, the role of CagA with respect to inducing
the loss of cell polarity is much clearer. The kinase
Par1b ... result of the length
restrictions of this minireview. The work of S.W. was
supported by the Deutsche Forschungsgemeinschaft
(We2843 ⁄ 2-1) and BGAG-Stiftung Walter Hesselbach.
The work of S.B. ... that
there is a controversy in the literature about the impor-
tance of the CagL RGD-motif in T4SS functions and
host cell signalling. Another unsolved question is the
proposed structure of CagY...
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Tài liệu Rethinking the Role of the State in Finance doc
Ngày tải lên :
16/02/2014, 10:20
... agency.
The roles of the The roles of the state in the financial sector include those of a pro-
state moter, owner, regulator, and overseer. The report focuses on areas
that were highlighted by the ... and Professor of Economics at the
Wharton School of the University of Pennsylvania
Thorsten Beck Professor of Economics and Chairman of the European Banking
Center, Tilburg University, Netherlands
Charles ... from around the world.
Two building blocks underlie the report’s
view of the role of the state in finance. First,
there are sound economic reasons for the
state to play an active role in financial...
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Tài liệu Báo cáo khoa học: A tyrosinase with an abnormally high tyrosine hydroxylase/dopa oxidase ratio Role of the seventh histidine and accessibility to the active site docx
Ngày tải lên :
19/02/2014, 07:20
... at pH 7. These preferred activities of
the two PPOs of R. solanacearum are opposite to the
names assigned to them when the genome of this bac-
terium was sequenced and the function of these con-
ceptual ... 1.10.3.1), but
the differentiation between these two types of enzyme
is not clear [4]. Looking at the sequences of the two
enzymes, both show absolute conservation of the histi-
dine residues of the CuA ... its
physiological role is uncertain. In fact, the role and
physiological advantages of the coexistence of several
PPOs in the same micro-organism remain unknown.
The synthesis of melanin in micro-organisms...
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Tài liệu Báo cáo khoa học: The role of the ESSS protein in the assembly of a functional and stable mammalian mitochondrial complex I (NADH-ubiquinone oxidoreductase) pptx
Ngày tải lên :
19/02/2014, 16:20
... must still be determined whether
its absence in the V79-G18 mutant is the result of the missing
ESSS subunit alone, or whether the absence of ESSS causes
the f ailure of other integral membrane subunits ... and the effect of
the absence of intact complex I, but the results are too
preliminary in this regard.
Heterologous expression of the ESSS-HA subunit
The localization of the ESSS subunit in the ... as a nother identification of
the complex at the position o f the histochemical stain in the
left panel. Antisera against the SDHC subunit of complex II
and against the Rieske protein of complex...
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Tài liệu Báo cáo khoa học: The role of the SEA (sea urchin sperm protein, enterokinase and agrin) module in cleavage of membrane-tethered mucins pdf
Ngày tải lên :
19/02/2014, 18:20
... required for efficient
cleavage [11].
The solution structure of the SEA domain of the
mouse homologue of MUC16 (which in the human
encodes the core protein of the ovarian cancer antigen
CA125) was ... further
investigate the role of the SEA domain in cleavage of
membrane-tethered mucins we carried out site-directed
mutagenesis of the FRPG ⁄ SVVV site and evaluated
hybrid mucins in which the ... ducts is of
considerable significance in the pathology of a number
of diseases including cystic fibrosis and cancer.
Equally important is the fate of the cytoplasmic tail
of the mucins once the extracellular...
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Tài liệu Báo cáo khoa học: Key role of the loop connecting the two beta strands of mussel defensin in its antimicrobial activity docx
Ngày tải lên :
20/02/2014, 11:20
... However, the 9-mer peptide B, CGGWHRLRC, corres-
ponding to the sequence of the MGD1 loop 3 occurring
between the two b-strands, had an MIC of 28 l
M
(i.e.
about 2.5% of the activity of the synthetic ... is not possible to infer whether
the key role of the b-hairpin loop of MGD1 (loop 3) in
antimicrobial activity of MGD1 is of general value in the
mechanism of action of defensins. However, our ... results obtained by other groups
who also point to the role of the connecting loop of the
b-hairpin of defensins. A combination of mutational
analysis [35] and structural analysis of the plant defensin
Rs-AFP1...
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Tài liệu Báo cáo Y học: Steady-state kinetics of the glutaminase reaction of CTP synthase from Lactococcus lactis The role of the allosteric activator GTP in coupling between glutamine hydrolysis and CTP synthesis potx
Ngày tải lên :
21/02/2014, 15:20
... locks the enzyme in the active form for CTP synthesis and
thereby stimulates the k
cat
of the reaction. Since GTP actually will
activate the uncoupled glutaminase reaction the structure of the
monomer ... was
similar to that of the overall CTP synthesis reaction. It
was concluded that the effect of GTP was mainly to
enhance the rate of chemical steps of the glutaminase
reaction. The finding that the k
cat
value ... as the displacement of the baseline. The peaks
observed at each injection time are derived from the heat of dilution
of glutamine into the reaction cell. (B) The heat generated by hydrolysis
of...
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Tài liệu UNIT 5. ONLINE FACILITATION LESSON 1. THE ROLE OF THE FACILITATOR pptx
Ngày tải lên :
22/02/2014, 01:20
... sense of group identity, in the eyes of its
members and those outside the group.
What is the role of the facilitator?
The role of the facilitator is to make it easier for
groups to work together ... 1. The Role of the Facilitator – page 6
What is the role of the facilitator?
How do facilitators help groups achieve their goals?
They do it by
ã Clarifying and reinforcing the purpose of the ... Facilitation - 1. The Role of the Facilitator – page 11
Group dynamics
Facilitators need to be aware both of the
communication styles of the individuals who
make up the group, and of the way the group...
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The Role of the Media in Promoting and Reducing Tobacco Use doc
Ngày tải lên :
06/03/2014, 01:20
... examine
the dynamics of tobacco-related media
interventions at each of these levels, within
a systemic framework.
The relationships among these levels and
stakeholders on either side of the tobacco ... product of the mass media era; the art and science of
mass communications and mass marketing were critical to the growth of tobacco use in the
past century. At the same time, however, the media ... underestimate
the effectiveness of the campaign.
n
Last, the all-pervasive nature of the media
environment includes both messages of
interest as well as background “noise.”
Given these challenges,...
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Báo cáo khoa học: Role of the C-terminal extension in a bacterial tyrosinase Michael Fairhead and Linda Thony-Meyer doc
Ngày tải lên :
06/03/2014, 11:20
... hypothe-
sized to be a result of the presence of an amino acid
that occludes the active site. This idea has been
proposed because of similarities in the structures of the
C-terminals of the related ... thus, the apparent shapes of the
unfolding curves should not be over interpreted. The
use of the concentration of GdnCl at 50% unfolded as
a simple measure of the change in stability between the
various ... further asses the functional importance of the
C-terminal extension, we created a shortened form of
the V. spinosum tyrosinase, using the presence of the
conserved YX(Y ⁄ F) motif as a guide. The...
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JUDGMENTS OF THE COURT OF APPEAL OF NEW ZEALAND ON PROCEEDINGS TO REVIEW ASPECTS OF THE REPORT OF THE ROYAL COMMISSION OF INQUIRY INTO THE MOUNT EREBUS AIRCRAFT DISASTER potx
Ngày tải lên :
06/03/2014, 12:21
... cannot be used to attack the
Royal Commission findings as to the cause of the crash. On behalf of the applicants it
was made clear nonetheless that their acceptance of the jurisdictional bar ... from the general body of the report. But the quashing of the costs order
because of its association with that paragraph is enough to do justice there.
The position is less clear as regards the ... Court Judge, the Erebus Commission was a Royal
Commission in that the warrant was expressed to be issued under the authority of the
Letters Patent of 1917 constituting the office of Governor-General....
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Role of The Controller - Mike Allred Associate Vice Chancellor for Finance & Controller UC-Davis doc
Ngày tải lên :
06/03/2014, 15:20
... Communications to the Regents
Committee on Audit
ã Letter of Comments & Recommendations to the
Regents
ã Letter of Comments & Recommendations to the
Chancellor
– Reports to the Board of Regents ... respect the rights and dignity of others
UC Standards of Ethical Conduct
1. Fair Dealing
ã No unlawful practice or a practice at odds with
these standards can be justified on the basis of
customary ...
confidence in the financial markets in the wake of
Enron, Tyco, Global Crossing, WorldCom,
HealthSouth…
– Created a new accounting oversight board to police the
practices of the accounting profession
–...
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Managing diffuse water pollution in South East Queensland: An analysis of the role of the Healthy Waterways Partnership docx
Ngày tải lên :
06/03/2014, 15:21
... analysis of the role of the Healthy Waterways Partnership – Cottingham, Franz Delfau, Garde
25
as well as the risk to the assets under the current flow management strategies (Department of the ... increased by 71%, amounting to 23% of the State’s direct output from the industrial sector. Mining
employed 3.2% of the local labour force during the period. The offices of the major mining companies ... what the
key issues are in the region and how they have arisen.
The second part of the report puts forward a critique of a program that targets one of the priority issues that
emerged from the...
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Báo cáo khoa học: Studies on the role of the receptor protein motifs possibly involved in electrostatic interactions on the dopamine D1 and D2 receptor oligomerization pdf
Ngày tải lên :
07/03/2014, 03:20
... possible
interpretation of the data suggests that the indicated
basic region of ic3 of the D
2
receptor and acidic region
of the C-tail of the D
1
receptor might be involved in
the interactions between the two ... on the number of Arg residues that
were replaced by Ala in the Arg-rich region of ic3 (resi-
dues 217–222) of the dopamine D
2
receptor. The effi-
ciency of energy transfer in the wild-type of the ... localization of these proteins in the cell rather than
from the possible role of the D
2
R basic domain in the mechanism of
D
1
–D
2
receptor heterodimerization. However, we find that the acidic
epitope...
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Báo cáo khoa học: Investigating the role of the invariant carboxylate residues E552 and E1197 in the catalytic activity of Abcb1a (mouse Mdr3) docx
Ngày tải lên :
07/03/2014, 06:20
... cleavage of the c-phosphate does occur in the
NBD with the mutation at the IC [36,38,39]. More-
over, these and other studies suggest that the IC
residues are involved in the formation of the NBD
dimer, ... sequence contacts the
c-phosphate of the bound nucleotide across the
dimer [15] and the aromatic residue of the A-loop
stacks against the adenine moiety of bound
nucleotide and provides further stabilization ... activates the attacking
water molecule that cleaves the terminal phosphate of
bound ATP. In the latter model, the IC is part of a
catalytic dyad, along with the histidine residue of the
H-loop,...
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