role of the b o coulomb repulsions for ferroelectricity and piezoelectricity

Báo cáo y học: " Ageing, autoimmunity and arthritis: Senescence of the B cell compartment — implications for humoral immunity" pptx

... & Therapy Vol No Johnson and Cambier present review we consider B lymphopoiesis in terms both of the complex process of mature B cell development from committed bone marrow (BM) progenitors, and ... development, and increased apoptosis of both pro -B and pre -B cells, have been purported to limit the pre -B cell pool in aged mice It has been shown in these animals that a proportion of pro- B cells ... Recently, however, investigators from the laboratory of Witte [17] contested this notion, concluding that despite reduced numbers of pre -B cells the rate of BrdU incorporation, and hence the rate of...

Ngày tải lên: 09/08/2014, 01:23

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Tài liệu Báo cáo khoa học: The role of the SEA (sea urchin sperm protein, enterokinase and agrin) module in cleavage of membrane-tethered mucins pdf

... from MUC12 largely abolishes cleavage Fig Model of SEA domain of MUC1 Ribbon representation of the modelled SEA domain of human MUC1 The model consists of three a-helices and six b- strands forming ... in the cleavage and sub–unit association of membrane-tethered glycoproteins is well documented but poorly understood Our aim was to evaluate the role of this domain in the processing of membrane-tethered ... due to poor sequence homology, we were not able to generate a reliable model of the SEA domain of MUC3 or MUC12 based on the solution structure of the MUC16 SEA domain derived by NMR spectroscopy...

Ngày tải lên: 19/02/2014, 18:20

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Báo cáo khoa học: MR solution structure of the precursor for carnobacteriocin B2, an antimicrobial peptide fromCarnobacterium piscicola Implications of the a-helical leader section for export and inhibition of type IIa bacteriocin activity pdf

... side of the membrane during export of the bioactive peptide [18] The leader peptide is undoubtedly recognized by the ABC protein responsible for export and processing In the case of carnobacteriocin ... of preCbnB2 structures (A) Superimposition of the backbone of the leader peptide a-helix for 20 structures (B) Superimposition of the backbone of helix Both helix domains are highly conserved ... this work describes the chemical synthesis and properties of the 66-amino acid bacteriocin precursor preCbnB2, and the biochemical production and isotopic labeling of preCbnB2(1–64), along with...

Ngày tải lên: 07/03/2014, 15:20

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Role of The Controller - Mike Allred Associate Vice Chancellor for Finance & Controller UC-Davis doc

... board to police the practices of the accounting profession – Strengthened auditor independence rules – Increased the accountability of corporate officers and directors – Improved disclosure and ... expected to demonstrate accountability for sponsors’ funds and to comply with specific terms and conditions of contracts and grants Research Noncompliance in Higher Education Cost of Not Doing the ... UCD for 2004-05 Influence of Sarbanes-Oxley Act on UC FYE Certification Letter Representations made by signatory to Controller: Responsible for the applications of University P&P Responsible for...

Ngày tải lên: 06/03/2014, 15:20

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Báo cáo khoa học: Critical role of the plasma membrane for expression of mammalian mitochondrial side chain cleavage activity in yeast pptx

... ergosta-5-eneol availability and electron carrier expression level on the production of pregnenolone and progesterone, and we also determined the localization of the components of the SCC reaction We found ... ergosta-5-eneol remains the main sterol (Fig 2B) Thus, the production of both pregnenolone and progesterone correlates with the depletion of ergosta-5-eneol and the accumulation of ergosta-5-eneol precursors ... concentrations of the steroid (Fig 5) Therefore, these results reveal two levels of complexity of the CYP11A1 reaction in yeast On one hand, the content of free ergosta-5-eneol poorly correlates with the...

Ngày tải lên: 08/03/2014, 08:20

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Center for Audit Quality Observations on the Evolving Role of the Auditor: A Summary of Stakeholder Discussions doc

... Director CENTER FOR AUDIT QUALITY OBSERVATIONS ON THE EVOLVING ROLE OF THE AUDITOR—A SUMMARY OF STAKEHOLDER DISCUSSIONS Introduction Over the years, the role of the public company auditor has been ... to examine the role of the auditor and the value of the audit On June 21 the PCAOB issued a concept release on potential revisions to the auditor’s reporting model Topics raised for public comment ... academics, board members and audit committee members) ROLE OF THE AUDITOR – AREAS FOR FURTHER CONSIDERATION INFORMATION ABOUT THE AUDIT • • A uditors could identify for investors the areas of highest...

Ngày tải lên: 15/03/2014, 20:20

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Báo cáo khoa học: Carbohydrate binding sites in Candida albicans exo-b-1,3-glucanase and the role of the Phe-Phe ‘clamp’ at the active site entrance ppt

... than for the F144A mutation Examination of the crystal structure of the F258I mutant showed it to be isomorphous with native Exg other than a small adjustment in the backbone conformation of loop ... mechanismbased inhibitors, thereby revealing the close network of interactions that hold the terminal glucose of the bglucan substrate in the )1 subsite at the bottom of the active site pocket [20] The ... only small protein conformational changes occur upon binding, whereas water molecules are positioned to mimic the sugar hydroxyl groups in the unbound form of the protein [32] Both of these characteristics...

Ngày tải lên: 15/03/2014, 23:20

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Báo cáo khoa học: Essential role of the C-terminus in Melanocarpus albomyces laccase for enzyme production, catalytic properties and structure pdf

... loses its chloride ion and probably also the T2 copper, as the B- value of the T2 copper was rather high On the basis of the anomalous signal, the estimated occupancy of the T2 copper was about ... inhibitor of MaL According to spectroscopic measurements, the binding of azide has been suggested to bridge the T2 copper and one of the T3 coppers [13,14], or bind to one T3 copper, as observed ... on the basis of antibody detection on dot blots Puriﬁcation of the laccases was followed by SDS ⁄ PAGE analysis Determination of protein concentration, SDS ⁄ PAGE, and western blot The protein...

Ngày tải lên: 16/03/2014, 00:20

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WORKING PAPER NO. 218 THE ZERO-INTEREST-RATE BOUND AND THE ROLE OF THE EXCHANGE RATE FOR MONETARY POLICY IN JAPAN potx

... conference, the Bank of Canada, the London School of Economics and the European Central Bank The opinions expressed are those of the authors and not necessarily reflect views of the European Central Bank.Volker ... function of the level of the equilibrium rate i∗ With an equilibrium nominal rate of 3%, the zero bound represents a constraint for monetary policy for about 10% of the time It becomes substantially ... scenario such as the one discussed above, we now compute the distributions of output and inﬂation in the presence of the zero bound by means of stochastic simulations 18 ECB • Working Paper No 218...

Ngày tải lên: 22/03/2014, 23:20

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Báo cáo khoa học: The yeast stress response Role of the Yap family of b-ZIP transcription factors The PABMB Lecture delivered on 30 June 2004 at the 29th FEBS Congress in Warsaw potx

... only with activation of FRM2 transcription, but also with growth in increasing concentrations of cadmium but not of H 2O2 Because of the high degree of homology to Yap1, the role of the Yap2 cysteine ... the formation of an intermolecular bond occurs between the Orp1 Cys36 and the Cys598 of Yap1 leading to its activation The subsequent formation of the Yap1 Cys303-Cys598 disulﬁde bond masks the ... suggested that Ybp1 could act as chaperoning the formation of disulﬁde bonds through the guiding of Orp1 Cys36SOH to Yap1 Cys598, and ⁄ or preventing the formation of the competing Orp1 Cys36-Cys82...

Ngày tải lên: 30/03/2014, 16:20

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Báo cáo y học: "κ The roles of the classical and alternative nuclear factor-κB pathways: potential implications for autoimmunity and rheumatoid arthritis" ppsx

... inflammation RA is a chronic inflammatory disease of the joints in which infiltration of immunocompetent cells and the proliferation of synovial fibroblasts of the joint lining leads to formation of ... to downregulation of osteoprotegerin, the natural antagonist of RANKL [111,112] The increased ratio of RANKL over osteoprotegerin assures generation of osteoclasts from monocyte precursors and ... account for up to 40% of the synovial cellular infiltrate [85] Self-antigen specific T cells play a role in the production of autoantibodies by providing help to B cells, probably both locally and...

Ngày tải lên: 09/08/2014, 10:23

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báo cáo khoa học: " Recent insights into the role of NF-κB in ovarian carcinogenesis" pot

... regulation This is the canonical pathway; there is also a non-canonical pathway involving other NF- B family members Most of the studies on EOC have looked at the members of the canonical pathway the ... binding to receptors (such as TNFα and TLR4) leads to the activation of the IKK complex, which then phosphorylates I B Phosphorylated I B is then ubiquitinated and degraded by the proteasome system, ... anchorage-independent growth and the capacity of the cells to invade through a basement membrane More importantly, the authors [16] identified the network of genes controlled by the IKKβ-NF- B pathway in CAOV3 cells...

Ngày tải lên: 11/08/2014, 12:20

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Báo cáo y học: " Angiotensin-converting enzyme 2 autoantibodies: further evidence for a role of the renin– angiotensin system in inflammation" potx

... undermine this compensatory response Indeed, identification of endogenous ACE2 inhibitors is important in lieu of optimizing the therapeutic benefits following administration of recombinant soluble ACE2, ... demonstrated in models of diabetic nephropathy [8] and liver fibrosis [9] or in the genetic expression of ACE2 in pulmonary hypertension [10] Page of Although the ongoing study of the renin–angiotensin ... markedly lower in comparison with the control group Indeed, the authors report the presence of circulating levels of ACE2 antibodies that exhibit inhibitory activity in vitro Previous studies showed...

Ngày tải lên: 12/08/2014, 14:22

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Báo cáo y học: " The sequence of the CA-SP1 junction accounts for the differential sensitivity of HIV-1 and SIV to the small molecule maturation inhibitor 3-O-{3'''',3''''-"</h1> Chia sẻ: <a href="http://tailie

... SIVm3 virions was only moderately affected by DSB as compared to the more pronounced effects of the compound on cleavage of HIV-1 Page of 10 (page number not for citation purposes) Retrovirology 2004, ... observations are consistent with the small but detectable accumulation of CA-SP1 observed in immunoblots of the SIVm3 virions, and support the conclusion that the DSB sensitivity of SIVm3 results from ... selection of HIV-1 for replication in moderate concentrations of DSB resulted in mutations at the P1 and P1' positions of this cleavage site, either of which conferred modest resistance to the compound...

Ngày tải lên: 13/08/2014, 13:20

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An evaluation of the material “basic english iii” for the second year non- english major students at bac giang teachers’ training college

... to be very useful and appropriate for evaluating a course book However, such frameworks are more suitable for the selection of course books available in the market than for the examination of ... evaluation often takes place before the course starts with the aim to select the appropriate materials most appropriate for the particular group of learners and for the aims of the course Formative or ... to the Aims of the Course To determine the appropriateness of the material to the aims of the course, the author has based upon the analysis of the syllabus objectives and that of the material...

Ngày tải lên: 07/11/2012, 14:50

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Preparation and characterization of the PVDF-based composite membrane for direct methanol fuel cells

... can be seen that the polymerization of styrene and the blending of PS and SPS polymers have affected the surface structure of the PVDF membrane obviously The cross-section morphologies of the ... at about 520 K corresponds to the decomposition of the PS polymer component The second major weight loss commences at about 710 K, corresponding to the decomposition of the PVDF main chains [28] ... time for PVDF-SPS membranes and Nafion-117 membrane 3.8 Oxidative stability of the PVDF-SPS composite membrane Oxidative stability of proton exchange membranes is one of the most important factors...

Ngày tải lên: 05/09/2013, 16:11

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136 Best Models Essays - Discuss the role of the police force in society

Ngày tải lên: 25/10/2013, 05:20

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Tài liệu Blonde and Blue eyed? The Globalization of the Beauty Industry - Geoff Jones for Von Gremp doc

... international distribution and production facilities The profitability of the cosmetics, and the potential for globalization, provided major attractions Yet the outcomes turned out to be unsuccessful ... countries the regular use by women of color cosmetics, hair dyes and other transformational products beauty products no longer carried connotations of immorality, and consumption spread far beyond ... lack of hygienic habits by indigenous Africans formed an important component of colonial racist rhetoric.29 The profound impact of the diffusion of Western beauty ideals can be seen in the case of...

Ngày tải lên: 10/12/2013, 04:15

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Tài liệu TREES OF THE NORTHERN UNITED STATES THEIR STUDY, DESCRIPTION AND DETERMINATION FOR THE USE OF SCHOOLS AND PRIVATE STUDENTS doc

... important The great office of the roots of all plants is the taking in of food from the soil Thick or fleshy roots, such as the radish, are stocks of food prepared for the future growth of the ... disagreeable odors when in bloom, but the other is nearly odorless By using the roots or the suckers of the third kind, only those which would be pleasant to have in a neighborhood would be obtained One ... appearance of the bark of the trunk, due to the many varieties of surface caused by the allowance for growth None of the characteristics of trees afford a better opportunity for careful observation and...

Ngày tải lên: 13/02/2014, 12:20

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