role of search engines in intelligent information retrieval on web
Báo cáo y học: "Functional genomics analysis of low concentration of ethanol in human hepatocellular carcinoma (HepG2) cells. Role of genes involved in transcriptional and translational processes"
... 46]. In conclusion, the functional genomics analysis presented in this investigation confirms the effect of ethanol at low concentration (1 mM) on the expression of genes involved in transcriptional ... subunit of the regulatory component of the proteasome. Based on the conserved gene expression profile in confluent HepG2 cells in vitro [21], the regulation of genes involved in transcriptional ... expression and activation of cytokines and chemokines in monocytes and macrophages (including Kupffer cells) [41, 42], and ethanol-induced mucosal injury in the upper gastrointestinal tract leading...
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Globalization: the Role of Institution Building in the Financial Sector _ The Case Study of China
... application of information technology, in exploring on- line banking business as well as in promotingnon-bank financial institutions. Efforts should be made in upgrading financialoperations and financial ... process of financial deepening in the developing countries. He suggests that as financial 7F. Role of the government, central bank and international financialinstitution in institution building1. ... bond trading system of the inter-bank lending centre. The tradingsystem of the national inter-bank lending centre provides pricing information, settlethe bond transaction and handle the bond...
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Tài liệu Báo cáo khoa học: Role of Kupffer cells in pathogenesis of sepsis-induced drug metabolizing dysfunction pptx
... employed GdCl3to inactivate KCs based on the findings of other investigators showing thedestruction of KCs after the intravenous administra-tion of GdCl3[15]. Hardonk et al. [15] demonstratedthat ... of KCs. Our findings suggest that ablation of KCsprotects against hepatic drug-metabolizing dysfunction by modulation of the in ammatory response.AbbreviationsALT, alanine aminotrasferase; ... shown that interactions betweenKCs and endotoxin comprise the initiating event lead-ing to hepatotoxicity in liver injury, including endotox-emia and ischemia ⁄ reperfusion injury [14]. In ourstudies,...
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Tài liệu The Role of BCG Vaccine in the Prevention and Control of Tuberculosis in the United States: A Joint Statement by the Advisory Council for the Elimination of Tuberculosis and the Advisory Committee on Immunization Practices docx
... renewed interest in examining the indications for BCG vaccination in theUnited States included consideration of the wide range of vaccine efficacies deter-mined by clinical trials and estimated in ... should continue to be included in ongoing testing programs if their skin-testresults are <5 mm induration. Those vaccinees who have positive tuberculin skin-testreactions (≥5 mm of induration) ... 5Vaccine Efficacy 5Vaccine Safety 7Tuberculin Skin Testing and Interpretation of Results After BCG Vaccination 8Recommendations 10BCG Vaccination for Prevention and Control of TBAmong Children...
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Tài liệu Rethinking the Role of the State in Finance doc
... expanding credit information sharing, and increasing payment system interconnection. In this context, consumer protection laws have been at the forefront of competition policies in many ... would involve the following determinations: in terms of producing information about possible invest-ments and allocating capital, the financial (a) developing and analyzing measures of the ... functionsProducing information about investments and allocate capital; monitoring investments and exerting corporate governance; managing risks; pooling savings; and easing the exchange of goods...
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Tài liệu The Role of Community Banks in the U.S. Economy pdf
... used this information topredict how the size distribution of banks would respond to a recentepisode of deregulation—the elimination of virtually all restrictions on interstate banking in the Reigle-Neal ... spread of online banking. The last several yearshave witnessed a sharp increase in the number of banks that allow cus-tomers to conduct business online—for example, verify account information, ... CITYbasing decisions on personal knowledge of customers’ creditworthinessand a keen understanding of business conditions in the communitiesthey serve. In this way, the bifurcated banking system...
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Tài liệu SICK WATER? THE CENTRAL ROLE OF WASTEWATER MANAGEMENT IN SUSTAINABLE DEVELOPMENT pdf
... (WWAP, 2009). Industrial dis-charge can contain a wide range of contaminants and originate from a myriad of sources. Some of the biggest generators of toxic industrial waste include mining, pulp ... from mining operations can contain silt and rock particles and sur-factants. Depending on the type of ore deposit being mined, tailings can also contain heavy metals like copper, lead, zinc, ... examples of persistent environmental damage caused by the discharge of toxic mine waste. In Papua New Guinea for ex-ample, companies discharge millions of tons of contaminated mine waste into...
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Tài liệu Báo cáo khoa học: A role of miR-27 in the regulation of adipogenesis ppt
... days in the differenti-ation medium: DMEM containing 10% fetal bovine serumand IDM (10 lgặmL)1insulin, 1 lm dexamethasone, and0.5 mm IDM). Cells were then maintained in DMEM con-taining ... differentiationwas initiated at 48 h post-transfection by maintaining the cells in culture medium containing 2% horse serum. Cells were fixed on day 4 of differentiation and stained with hematoxylin and ... USA) and maintained in the culture condi-tions recommended by the ATCC. Briefly, 3T3-L1 cellswere cultured in DMEM containing 10% fetal bovineserum. OP9 cells were grown in aMEM containing 20%fetal...
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Tài liệu Báo cáo khoa học: Emerging pathways in genetic Parkinson’s disease: Potential role of ceramide metabolism in Lewy body disease pptx
... destinations.Cells from NPC subjects show a decrease in acidsphingomyelinase activity, leading to the accumulation of sphingomyelin [27]. Because one of the pathwaysfor ceramide recycling ... mutation in the gene encodingalpha-synuclein in Parkinson’s disease. Nat Genet 18,106–108.42 Singleton AB, Farrer M, Johnson J, Singleton A,Hague S, Kachergus J, Hulihan M, Peuralinna T, ... cel-lular response to this altered ceramide metabolism.Also connecting the ceramide pathway to a-synucleindeposition is the recent description of an increase in a-synuclein inclusions in Caenorhabditis...
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Tài liệu Báo cáo khoa học: Role of ceramide kinase in peroxisome proliferatoractivated receptor beta-induced cell survival of mouse keratinocytes ppt
... and its role in regulating keratino-cyte survival. We report that in a mouse keratinocytecell line upregulation of CERK expression by activa-tion of PPARb results in a decrease in intracellularCer ... tran-scription of the CERK gene. The conversion of Cer to C1P by the produced CerK results in decreased levels of intracellular Cer, andthe inhibition of stress-induced cell death.The interaction between ... [13]. Interestingly,expression of ABCA12 mRNA has been shown to beinduced by activation of PPARb or PPARc in culturedhuman keratinocytes [14]. In this study, we examined the interaction betweenCerK...
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Tài liệu Báo cáo khoa học: The role of electrostatic interactions in the antitumor activity of dimeric RNases docx
... strong, neutralizing action of the cytosolic RNaseinhibitor (cRI), a 50-kDa protein containing 16 leu-cine-rich repeat motifs [7,8]. In fact, onconase fromRana pipiens eggs [9], and seminal ... catalytic, RNA degradingaction [2]. These actions could be linked to physiologi-cal functions, as in the case of the angiogenic action of angiogenins [3], or due to the mere reflection in thelaboratory ... model of exchanging RNaseAA dimer based on the exchanging structure of BS-RNase.The hinge loop, i.e., the loop which adopts different confor-mations in the exchanging and nonexchanging BS-RNasedimers,...
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Tài liệu Báo cáo khoa học: The role of N-glycosylation in the stability, trafficking and GABA-uptake of GABA-transporter 1 Terminal N-glycans facilitate efficient GABA-uptake activity of the GABA transporter pptx
... substratebinding process. This provides strong evidence thatN-glycans, in particular their terminal structures, areinvolved in regulating the GABA translocation of GAT1, but not in binding of GAT1 ... expression of transporters. In thisevent the oligosaccharides of GAT1 play a role in theregulation of GABA-uptake by affecting the affinityfor sodium ions. In conclusion, cotranslational N-glycosylation ... theterminal structures of the N-glycans of GAT1, N-gly-cosylation processing of NNN was inhibited by 1-de-oxymannojirimycin (dMM). Inhibition by dMM leadsto the formation of NNN molecules containing...
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Tài liệu Báo cáo khoa học: "Kinds of Features for Chinese Opinionated Information Retrieval" pdf
... capable of pro-viding access to opinionated information in otherlanguages (especially in Chinese) might be of greatuse for individuals as well as for institutions in- volved in international ... whichis the context for the experiments described in thepaper will consist of four main modules:1. Query translation2. Opinionated Information Retrieval 3. Opinionated Information Extraction4. Results ... or international rela-tions.The sentiment classification experiments pre-sented in this paper were done in the context of Opinionated Information Retrieval which is plannedto be a module in...
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Tài liệu Báo cáo khoa học: "From HOPE en I''''ESPERANCE On the Role of Computational Neurolinguistics in Cross-Language Studies " pptx
... activation of all meanings of each recognized word in HOPE, the determination of the phonetic representation of a recognized word determines the breadth of active competition amon 9 meanings ... MEANING-PROPAGATION: Fixed-time spreading activation to the distributed parts of recognized words ' meanings. 6. FIRING -INFORMATION- PROPAGATION: Asynchronous activation propagation that ... marked by intonation or pauses. However, for French this is not the case. Depending on the context, the ending of one word may be phone- tically affixed to the following one called liason. In addition,...
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The Role of the Media in Promoting and Reducing Tobacco Use doc
... and adults, often only one part of multicomponent interventions; and (2) population-level studies, including both longitudinal and cross-sectional evaluation studies of national- and state-level ... 8Preparation of this Monograph 10Monograph Organization 10Major Conclusions 11Chapter Summaries and Conclusions 12References 23Chapter 2—Theoretical Underpinnings of Media Research in Tobacco Control ... stakeholders on either side of the tobacco Figure 1.1 The Nested Relationships among Advertising, Marketing Communications, Consumer Marketing, and Stakeholder Marketing in Tobacco PromotionTelevisionBillboards...
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