Ngày tải lên: 31/03/2014, 00:20
Ngày tải lên: 02/11/2014, 00:47
Báo cáo y học: "Functional genomics analysis of low concentration of ethanol in human hepatocellular carcinoma (HepG2) cells. Role of genes involved in transcriptional and translational processes"
... 46]. In conclusion, the functional genomics analysis presented in this investigation confirms the effect of ethanol at low concentration (1 mM) on the expression of genes involved in transcriptional ... subunit of the regulatory component of the proteasome. Based on the conserved gene expression profile in confluent HepG2 cells in vitro [21], the regulation of genes involved in transcriptional ... expression and activation of cytokines and chemokines in monocytes and macrophages (including Kupffer cells) [41, 42], and ethanol-induced mucosal injury in the upper gastrointestinal tract leading...
Ngày tải lên: 31/10/2012, 15:28
The role of leadership theory in raising the profile of women in management
Ngày tải lên: 08/10/2013, 15:56
Globalization: the Role of Institution Building in the Financial Sector _ The Case Study of China
... application of information technology, in exploring on- line banking business as well as in promoting non-bank financial institutions. Efforts should be made in upgrading financial operations and financial ... process of financial deepening in the developing countries. He suggests that as financial 7 F. Role of the government, central bank and international financial institution in institution building 1. ... bond trading system of the inter-bank lending centre. The trading system of the national inter-bank lending centre provides pricing information, settle the bond transaction and handle the bond...
Ngày tải lên: 18/10/2013, 07:15
Tài liệu Báo cáo khoa học: Role of Kupffer cells in pathogenesis of sepsis-induced drug metabolizing dysfunction pptx
... employed GdCl 3 to inactivate KCs based on the findings of other investigators showing the destruction of KCs after the intravenous administra- tion of GdCl 3 [15]. Hardonk et al. [15] demonstrated that ... of KCs. Our findings suggest that ablation of KCs protects against hepatic drug-metabolizing dysfunction by modulation of the in ammatory response. Abbreviations ALT, alanine aminotrasferase; ... shown that interactions between KCs and endotoxin comprise the initiating event lead- ing to hepatotoxicity in liver injury, including endotox- emia and ischemia ⁄ reperfusion injury [14]. In our studies,...
Ngày tải lên: 14/02/2014, 18:20
Tài liệu The Role of BCG Vaccine in the Prevention and Control of Tuberculosis in the United States: A Joint Statement by the Advisory Council for the Elimination of Tuberculosis and the Advisory Committee on Immunization Practices docx
... renewed interest in examining the indications for BCG vaccination in the United States included consideration of the wide range of vaccine efficacies deter- mined by clinical trials and estimated in ... should continue to be included in ongoing testing programs if their skin-test results are <5 mm induration. Those vaccinees who have positive tuberculin skin-test reactions (≥5 mm of induration) ... 5 Vaccine Efficacy 5 Vaccine Safety 7 Tuberculin Skin Testing and Interpretation of Results After BCG Vaccination 8 Recommendations 10 BCG Vaccination for Prevention and Control of TB Among Children...
Ngày tải lên: 15/02/2014, 13:20
Tài liệu Rethinking the Role of the State in Finance doc
... expanding credit information sharing, and increasing payment system interconnection. In this context, consumer protection laws have been at the forefront of competition policies in many ... would involve the following determinations: in terms of producing information about possible invest- ments and allocating capital, the financial (a) developing and analyzing measures of the ... functions Producing information about investments and allocate capital; monitoring investments and exerting corporate governance; managing risks; pooling savings; and easing the exchange of goods...
Ngày tải lên: 16/02/2014, 10:20
Tài liệu The Role of Community Banks in the U.S. Economy pdf
... used this information to predict how the size distribution of banks would respond to a recent episode of deregulation—the elimination of virtually all restrictions on interstate banking in the Reigle-Neal ... spread of online banking. The last several years have witnessed a sharp increase in the number of banks that allow cus- tomers to conduct business online—for example, verify account information, ... CITY basing decisions on personal knowledge of customers’ creditworthiness and a keen understanding of business conditions in the communities they serve. In this way, the bifurcated banking system...
Ngày tải lên: 16/02/2014, 11:20
Tài liệu SICK WATER? THE CENTRAL ROLE OF WASTEWATER MANAGEMENT IN SUSTAINABLE DEVELOPMENT pdf
... (WWAP, 2009). Industrial dis- charge can contain a wide range of contaminants and originate from a myriad of sources. Some of the biggest generators of toxic industrial waste include mining, pulp ... from mining operations can contain silt and rock particles and sur- factants. Depending on the type of ore deposit being mined, tailings can also contain heavy metals like copper, lead, zinc, ... examples of persistent environmental damage caused by the discharge of toxic mine waste. In Papua New Guinea for ex- ample, companies discharge millions of tons of contaminated mine waste into...
Ngày tải lên: 17/02/2014, 10:20
Tài liệu Báo cáo khoa học: A role of miR-27 in the regulation of adipogenesis ppt
... days in the differenti- ation medium: DMEM containing 10% fetal bovine serum and IDM (10 lgặmL )1 insulin, 1 lm dexamethasone, and 0.5 mm IDM). Cells were then maintained in DMEM con- taining ... differentiation was initiated at 48 h post-transfection by maintaining the cells in culture medium containing 2% horse serum. Cells were fixed on day 4 of differentiation and stained with hematoxylin and ... USA) and maintained in the culture condi- tions recommended by the ATCC. Briefly, 3T3-L1 cells were cultured in DMEM containing 10% fetal bovine serum. OP9 cells were grown in aMEM containing 20% fetal...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khoa học: Emerging pathways in genetic Parkinson’s disease: Potential role of ceramide metabolism in Lewy body disease pptx
... destinations. Cells from NPC subjects show a decrease in acid sphingomyelinase activity, leading to the accumulation of sphingomyelin [27]. Because one of the pathways for ceramide recycling ... mutation in the gene encoding alpha-synuclein in Parkinson’s disease. Nat Genet 18 , 106–108. 42 Singleton AB, Farrer M, Johnson J, Singleton A, Hague S, Kachergus J, Hulihan M, Peuralinna T, ... cel- lular response to this altered ceramide metabolism. Also connecting the ceramide pathway to a-synuclein deposition is the recent description of an increase in a-synuclein inclusions in Caenorhabditis...
Ngày tải lên: 18/02/2014, 14:20
Tài liệu Báo cáo khoa học: Role of ceramide kinase in peroxisome proliferatoractivated receptor beta-induced cell survival of mouse keratinocytes ppt
... and its role in regulating keratino- cyte survival. We report that in a mouse keratinocyte cell line upregulation of CERK expression by activa- tion of PPARb results in a decrease in intracellular Cer ... tran- scription of the CERK gene. The conversion of Cer to C1P by the produced CerK results in decreased levels of intracellular Cer, and the inhibition of stress-induced cell death. The interaction between ... [13]. Interestingly, expression of ABCA12 mRNA has been shown to be induced by activation of PPARb or PPARc in cultured human keratinocytes [14]. In this study, we examined the interaction between CerK...
Ngày tải lên: 18/02/2014, 18:20
Tài liệu Báo cáo khoa học: The role of electrostatic interactions in the antitumor activity of dimeric RNases docx
... strong, neutralizing action of the cytosolic RNase inhibitor (cRI), a 50-kDa protein containing 16 leu- cine-rich repeat motifs [7,8]. In fact, onconase from Rana pipiens eggs [9], and seminal ... catalytic, RNA degrading action [2]. These actions could be linked to physiologi- cal functions, as in the case of the angiogenic action of angiogenins [3], or due to the mere reflection in the laboratory ... model of exchanging RNase AA dimer based on the exchanging structure of BS-RNase. The hinge loop, i.e., the loop which adopts different confor- mations in the exchanging and nonexchanging BS-RNase dimers,...
Ngày tải lên: 19/02/2014, 06:20
Tài liệu Báo cáo khoa học: The role of N-glycosylation in the stability, trafficking and GABA-uptake of GABA-transporter 1 Terminal N-glycans facilitate efficient GABA-uptake activity of the GABA transporter pptx
... substrate binding process. This provides strong evidence that N-glycans, in particular their terminal structures, are involved in regulating the GABA translocation of GAT1, but not in binding of GAT1 ... expression of transporters. In this event the oligosaccharides of GAT1 play a role in the regulation of GABA-uptake by affecting the affinity for sodium ions. In conclusion, cotranslational N-glycosylation ... the terminal structures of the N-glycans of GAT1, N-gly- cosylation processing of NNN was inhibited by 1-de- oxymannojirimycin (dMM). Inhibition by dMM leads to the formation of NNN molecules containing...
Ngày tải lên: 19/02/2014, 17:20
Tài liệu Báo cáo khoa học: "Kinds of Features for Chinese Opinionated Information Retrieval" pdf
... capable of pro- viding access to opinionated information in other languages (especially in Chinese) might be of great use for individuals as well as for institutions in- volved in international ... which is the context for the experiments described in the paper will consist of four main modules: 1. Query translation 2. Opinionated Information Retrieval 3. Opinionated Information Extraction 4. Results ... or international rela- tions. The sentiment classification experiments pre- sented in this paper were done in the context of Opinionated Information Retrieval which is planned to be a module in...
Ngày tải lên: 20/02/2014, 12:20
Tài liệu Báo cáo khoa học: "From HOPE en I''''ESPERANCE On the Role of Computational Neurolinguistics in Cross-Language Studies " pptx
... activation of all meanings of each recognized word in HOPE, the determination of the phonetic representation of a recognized word determines the breadth of active competition amon 9 meanings ... MEANING-PROPAGATION: Fixed-time spreading activation to the distributed parts of recognized words ' meanings. 6. FIRING -INFORMATION- PROPAGATION: Asynchronous activation propagation that ... marked by intonation or pauses. However, for French this is not the case. Depending on the context, the ending of one word may be phone- tically affixed to the following one called liason. In addition,...
Ngày tải lên: 21/02/2014, 20:20
The Role of the Media in Promoting and Reducing Tobacco Use doc
... and adults, often only one part of multicomponent interventions; and (2) population-level studies, including both longitudinal and cross-sectional evaluation studies of national- and state-level ... 8 Preparation of this Monograph 10 Monograph Organization 10 Major Conclusions 11 Chapter Summaries and Conclusions 12 References 23 Chapter 2—Theoretical Underpinnings of Media Research in Tobacco Control ... stakeholders on either side of the tobacco Figure 1.1 The Nested Relationships among Advertising, Marketing Communications, Consumer Marketing, and Stakeholder Marketing in Tobacco Promotion Television Billboards...
Ngày tải lên: 06/03/2014, 01:20
Enterprise Adjustment and the Role of Bank Credit in Russia: Evidence from a 420 Firm''''s Qualitative Survey pdf
Ngày tải lên: 06/03/2014, 08:20
BEYOND MICROCREDIT: THE ROLE OF SAVINGS BANKS IN MICROFINANCE potx
Ngày tải lên: 06/03/2014, 10:20