role of oxidative stress

... rate and differentiation of F9 cells were not affected by the over-expression of Hsp105a, the sensitivity of cells to oxidative stress was enhanced by the over-expression of Hsp105a,andthese findings ... over-expression of Hsp105a seemed to enhance the release of cytochrome c from mitochondria in F9 cells by hydrogen peroxide. Fig. 3. Enhancement of oxidative stress- induced apoptosis by over-expression of ... apoptosis at or upstream of cytochrome c release from mitochondria. Furthermore, the transmission of signals from external stresses is accompanied by the activation of a family of stress- activated protein...

Ngày tải lên: 21/02/2014, 03:20

... Agarwal A, Krajcir N, Alvarez JG: Role of oxidative stress in endometriosis. Reprod Biomed Online 2006, 13:126–134. 22. Agarwal A, Gupta S, Sharma RK: Role of oxidative stress in female reproduction. ... toxins: pervasive theme of oxidative stress and electron transfer. Curr Med Chem 2001, 8:863–892. 323. Kovacic P, Sacman A, Wu-Weis M: Nephrotoxins: widespread role of oxidative stress and electron ... CM, Gupta S, Agarwal A: Could oxidative stress influence the in-vitro maturation of oocytes? Reprod Biomed Online 2009, 18:864–880. 383. Sikka SC: Role of oxidative stress response elements and...

Ngày tải lên: 05/03/2014, 16:20

... 1997:190). 27 The pattern of stress in this sentence is stressed – unstressed – stressed – unstressed – stressed – unstressed, with equal number of alternating stressed and unstressed syllables. ... frequency usage of English sentence stress The chart below shows 13 of them (32.5%) indicate that they never use sentence stress while speaking. Some of them about 12.5% often use sentence stress in ... Misunderstanding of meaning caused by wrong placement of stress 49 2.2. Misunderstanding of meaning caused by changes in sentence stress. 50 2.3. Communication breakdown caused by wrong use of stress...

Ngày tải lên: 17/03/2014, 16:12

Ngày tải lên: 23/03/2014, 07:20

Ngày tải lên: 19/06/2014, 22:20

Ngày tải lên: 20/06/2014, 00:20

... boxes. Ó FEBS 2003 Role of 3,4-dihydrocoumarin hydrolase of Acinetobacter (Eur. J. Biochem. 270) 491 Role of Acinetobacter calcoaceticus 3,4-dihydrocoumarin hydrolase in oxidative stress defence ... probe. Ó FEBS 2003 Role of 3,4-dihydrocoumarin hydrolase of Acinetobacter (Eur. J. Biochem. 270) 489 deduced amino acid sequence of DCH exhibited high similarity to those of the esterases of Pseudomonas ... ability of dch to catalyse the peroxidation of organic acids, which could be an intermediary reaction of halogenation, and it is assumed that the role of DCH in vivo is the degradation of peroxoacids. Peroxoacids...

Ngày tải lên: 17/03/2014, 09:20

... and fragmentation of their nuclei. The percentage of apoptotic cells was calculated as the number of apoptotic cells divided by the total number of cells counted. A minimum of 500 cells were ... been suggested to play an important role in precondition- ing, a phenomenon of protection of a heart from strong ischaemic insult by prior exposure to mild ischaemia or other mild stresses. In the present study, ... additional protection against oxidant stress (Fig. 4D). Therefore, Hsp70-transfected cells with a higher level of nucleolin ⁄ C23 protein become more resistant to oxidative stress and less susceptible...

Ngày tải lên: 16/02/2014, 09:20

... [2]. Concentrations of aldehydes also increase with age and in diseases that are accompan- ied by oxidative stress. Oxidative stress causes lipid peroxidation and formation of aldehydes such as malon(di)aldehyde, ... acidic pH (b-hydroxyacrolein). The following investigations focus on the effects of acetaldehyde and acrolein because of the relevance of these aldehydes for the biological effects of ingested ethanol ... and Keywords acetaldehyde; acrolein; metallothionein; oxidative stress; zinc Correspondence W. Maret, Division of Human Nutrition, Preventive Medicine and Community Health, The University of Texas Medical Branch,...

Ngày tải lên: 19/02/2014, 06:20

... presence of catalase, whereas superoxide anion was likely to be of m inor importance i n formation of the radical cations [166]. Collectively, the drastic disruption of the C- and N -oxidative ... and N -oxidative biotransformation of aniline and its 4-chloro derivative [149,163] by the presence of catalase furnishes unequivocal e vidence f or a vital role of autoxidatively liberated H 2 O 2 in ... ring opening of an epoxide inter- mediate at either of its two C-O bonds [219,220]. The sum of these findings strongly invokes the notion of oxygen activation during redox cycling of the diverse dioxygenases...

Ngày tải lên: 19/02/2014, 16:20

... to oxidative stress affects c-Fos stability and BimEL expression by chang- ing the duration of the ERK signal. Therefore, the duration of oxidative stress might be a fundamental determinant of ... AP-1-dependent gene expression occurred under the conditions of sustained oxidative stress. This idea is supported by data show- ing that transient oxidative stress for 3 or 6 h did not induce apoptosis [38]. In ... expression of BimEL, a major isoform among the bim gene products, leading to apoptosis in rat primary hepato- cytes [15]. Bim is a member of the Bcl-2 family of proteins, which play a fundamental role...

Ngày tải lên: 06/03/2014, 00:21

... insights into the roles and mechan- isms of PM 2.5 -associated physiology and pathology. In summary, our data demonstrate the important effects of PM 2.5 exposure on oxidative stress and mito- chondrial ... number and area of mitochondria in the eWAT and iBAT. A-B. Representative TEM images of eWAT. C-D. Representative TEM images of iBAT (Arrows point to mitochondria). E: The analysis of mitochondrial ... 8:20 http://www.particleandfibretoxicology.com/content/8/1/20 Page 14 of 14 RESEARC H Open Access Ambient particulate air pollution induces oxidative stress and alterations of mitochondria and gene expression in brown...

Ngày tải lên: 06/03/2014, 19:20

... increase in the amount of ROS [21]; (b) loss of cytochrome c impairs the flow of electrons in the respiratory chain inducing over- reduction of the complexes, favouring the generation of ROS [16,17,22]; ... the ’Ca 2+ paradox’ In spite of the widely accepted role of [Ca 2+ ] c deregula- tion in the manifestation of neurodegeneration, exactly how Ca 2+ ions mediate neural cell death is less clear [185]. One of the most ... to oxidative stress is dependent on activa- tion of poly (ADP-ribose) polymerase. Br J Pharma- col 143, 186–192. 235 Balzer M, Lintschinger B & Groschner K (1999) Evidence for a role of Trp...

Ngày tải lên: 07/03/2014, 12:20

... data- base of the aerobic hyperthermophilic archaeon Sulfolobus solfataricus. Its role in oxidative stress was investigated by transcriptional analysis of RNA isolated from cultures that had been stressed ... hydroperoxide Fig. 4. Northern hybridization analysis of S. solfataricus P2 bcp2 transcripts: effect of oxidative stress agents. Cultures of S. solfataricus P2 were grown until the mid-exponential ... base of P. horikoshii nei- ther a homologue of A. pernix thioredoxin-like nor other types of thioredoxins were found. In this study we examined the involvement of the peroxiredoxin Bcp2 in oxidative...

Ngày tải lên: 07/03/2014, 12:20

... thought to elicit oxidative stress, and it is recog- nized that this may have a role in the progression of the disease (for review, see [18]). Usually, the occur- rence of oxidative stress is evaluated ... influence of oxidative stress on these processes. Our data clarify some of these aspects, and suggest that thiol-directed oxidative stress consider- ably influences the inter-organ exchange of cysteine ... long- lasting effects of thiol-directed oxidative stress, and, in particular, its influence on the inter-organ exchange of LMM-SH. Results In a first set of experiments, the kinetics of plasma thiols...

Ngày tải lên: 16/03/2014, 02:20

... Finkel T & Holbrook NJ (2000) Oxidants, oxidative stress and the biology of ageing. Nature 408, 239–247. 3 Jamieson DJ (1998) Oxidative stress responses of the yeast Saccharomyces cerevisiae. ... response of cells with dysfunctional mitochondria to oxidative stress, we evaluated H 2 O 2 sensitivity of deletion mutants for the regulators most frequently associated with oxidative stress response: ... oxi- dation of glutathione to the disulfide. Biochem Biophys Res Commun 37, 593–596. 41 Garrido EO & Grant CM (2002) Role of thioredoxins in the response of Saccharomyces cerevisiae to oxidative stress...

Ngày tải lên: 16/03/2014, 14:20

... resulted in a decrease of 0.29 ± 0.19 nmolÆmg )1 of mitochondrial protein. The combination of 3.5 lm Ca 2+ and H ⁄ R led to the substantial decrease in GSH of 1.27 ± 0.15 nmolÆmg )1 of mitochondrial ... conse- quences of stroke [3,4]. Moreover, the increase in lipid peroxidation after ischemia also points towards the involvement of oxidative stress [5,6]. Further investigations using animal models of stroke made ... radicals is com- plex I [14]. The degree of production of ROS by the respiratory chain depends on the type of tissue, the kind of substrates driving oxidative phosphorylation (either complex...

Ngày tải lên: 16/03/2014, 22:20

... residues and some of them have been implicated in oxidative stress response. Thus, it is very likely that this redox system forms the basis of annexin response to oxidative stress in that it reduces ... molecular basis for annexin function in oxidative stress response. Keywords: calcium; cellulose synthase; cotton; oxidative stress response; plant annexin. Oxidative stress is a health-threatening phenomenon ... structure of Anx(Gh1) from cotton emphasizes the high conservation of the unique annexin fold even among the members of the plant subfamily of annexin proteins. The fold is comprised of the arrangement...

Ngày tải lên: 17/03/2014, 03:20

Ngày tải lên: 22/03/2014, 16:20

Ngày tải lên: 23/03/2014, 15:21