role of hematopoietic stem cell transplantation

... QC, Zhu P: Patterns of T -cell reconstitution by assessment of T -cell receptor excision circle and T -cell receptor clonal repertoire after allogeneic hematopoietic stem cell transplantation in ... TRBV subfamilies of T cells, expansion of particular TRBV subfamily T cells has been recently determined by quantitative analysis of a series of TRBV-BD1 sjTRECs [8-11] However, T -cell proliferation ... immunodeficiency and recovery of a selfrestricted, diverse T -cell repertoire is dependent on thymic production of T cells from hematopoietic progenitors The appearance of sjTRECs after transplantation was...

Ngày tải lên: 10/08/2014, 21:23

... diagnose systemic inflammation in various patient populations A recent review of the role of PCT in febrile neutropenic patients suggested the superior role of PCT over other markers of Page of (page ... evaluated a cohort of 26 adult patients indicated for an ATG conditioning regimen prior to hematopoietic stem cell transplantation The patients were treated at the Institute of Hematology and ... used as part of a conditioning regimen in patients scheduled for allogeneic hematopoietic stem cell transplantation In those patients, freedom from infection before engraftment is of the utmost...

Ngày tải lên: 13/08/2014, 16:20

... marrow stem cell transplantation for severe systemic lupus erythematosus of long duration Lupus 1997, 6:545-548 Burt RK, Traynor A, Ramsey-Goldman R: Hematopoietic stemcell transplantation for systemic ... The hematopoietic stem cells are infused in order to shorten the past transplant neutropenic interval by 4–6 days compared with the same dose of cyclophosphamide without hematopoietic stem cell ... hematopoietic stem cell transplantation: getting closer to a cure? Blood 2002, 99:870-887 Traynor AE, Barr WG, Rosa RM, Rodriquez J, Oyama Y, Baker S, Brush M, Burt RK: Hematopoietic stem cell transplantation...

Ngày tải lên: 09/08/2014, 01:23

... Medical University; Member of the Asian-Pacific Society of Hematology; Member of Blood Branch of the Chinese Medical Association; Member of the Chinese hematopoietic stem cell transplant group; Standing ... provision of clinical care of the patient and the collection of data and the review of the manuscript GPY: supplied the acquisition of data, analysis and interpretation of data, drafting of manuscript; ... et al Journal of Hematology & Oncology 2011, 4:9 http://www.jhoonline.org/content/4/1/9 Page of Figure Bilirubin level during chemotherapy and allogeneic hematopoietic stem cell transplantation...

Ngày tải lên: 10/08/2014, 21:23

... trials, administered "megadose" of donor hematopoietic stem cells by combining G-CSF mobilized peripheral blood with bone marrow stem cells, both depleted of T cells, following TBI-based conditioning ... C: Hematopoietic stem cell transplants from unrelated donors Immunol Rev 1997, 157:141-151 20 21 22 Howe CWS, Radde-Stepaniak T: Hematopoietic cell donor registries In Hematopoietic cell transplantation ... C: Transplantation of hematopoietic stem cells from alternate donors in acute myelogenous leukemia Leukemia 2000, 14:502-504 Aversa F, Velardi A, Tabilio A, et al.: Haploidentical stem cell transplantation...

Ngày tải lên: 10/08/2014, 22:20

... after allogeneic hematopoietic stem cell transplantation Biology of Blood and Marrow Transplantation, 8, 674-682 Richards, S J., Morgan, G J., & Hillmen, P (1999) Analysis of T cells in paroxysmal ... nonmyeloablative versus conventional hematopoietic stem cell transplantation Blood, 102, 756-762 Parkman, R., & Weinberg, K I (2004) Immune reconstitution following hematopoietic cell transplantation In K G ... common after peripheral blood stem cell transplantation than BMT because it is generally accepted that peripheral blood stem cells con­ tain greater numbers of infused T-cells (Bishop, 2009; Schmitz...

Ngày tải lên: 12/02/2014, 19:20

... Suvivorship_Stages _of_ Recovery.pdf], Accessed April 1, 2011 Appelbaum FR: The current status of hematopoietic cell transplantation Annu Rev Med 2003, 54:491-512 Horowitz MM: Uses and growth of hematopoietic cell ... illness, malignant disease status at the time of transplantation, intensity of the preparative regimen, source of stem cell graft, and the extent of histoincompatibility between donor and recipient ... Health-related quality of life, symptom distress and sense of coherence in adult survivors of allogeneic stem- cell transplantation Eur J Cancer Care (Engl) 2001, 10(2):124-130 46 Lesko LM, Ostroff JS, Mumma...

Ngày tải lên: 20/06/2014, 15:20

... study of intravenous autologous mesenchymal stem cell transplantation in patients with ischemic stroke Stem Cells 2010, 28:1099-1106 Chou SH, Kuo TK, Liu M, Lee OK: In utero transplantation of human ... Average of rotarod performance of mouse which received intravenous human mesenchymal stem cells transplantation at sequential periods Average of latency to fall from rotarod (in seconds) of mice ... Effects of Umbilical Cord Blood-Derived Mesenchymal Stem Cell Transplantation in Experimental Lupus Nephritis Cell Transplant 2011, 20:245-257 32 Parekkadan B, Milwid JM: Mesenchymal stem cells...

Ngày tải lên: 10/08/2014, 10:20

... by washing cells times, then G-CSF (R&D Systems, Minneapolis, MN) was added to cells at a final concentration of 200 ng/ml CFU assay of BM cells Tubes of MethoCult® GF M3434 (Stem Cell Technologies, ... IL: A role for Wnt signalling in self-renewal of haematopoietic stem cells Nature 2003, 423:409-14 Antonchuk J, Sauvageau G, Humphries RK: HOXB4-induced expansion of adult hematopoietic stem cells ... Ishiko J, Nakajima K, Kanakura Y: Roles for c-Myc in self-renewal of hematopoietic stem cells J Biol Chem 2004, 279:24986-93 27 Nakano T: Hematopoietic stem cells: generation and manipulation...

Ngày tải lên: 10/08/2014, 21:23

... mononuclear cells of the patient pre-transplant, of the AML blast cell sample obtained after transplantation, and of the donor bone marrow cells The 11 tested microsatellite markers are often used ... patient’s pre- and post -transplantation (AML) cells and donor’s cells Polymorphism DNA repair mechanism Patient cells (pretransplantation) AML cells (posttransplantation) Donor cells XPA A23G NER ... donor’s cells, supporting full engraftment of the stem cell transplant as well as the donor cell- origin of the AML blasts Figure Bone marrow smear after allo-SCT relapse A- Note the presence of basophils...

Ngày tải lên: 10/08/2014, 21:23

... Rodriguez V, Khan SP: Use of prophylactic anticoagulation and the risk of hepatic venoocclusive disease in patients undergoing hematopoietic stem cell transplantation: a systematic review and meta-analysis ... GB, Guinan EC: Multi-institutional use of defibrotide in 88 patients after stem cell transplantation Page of (page number not for citation purposes) Journal of Medical Case Reports 2009, 3:6164 ... general, management of SOS should be based on prophylaxis: identification of patients at risk, avoidance of SOSinducing therapies, preventative medical therapy [9] and, finally, therapy of the syndrome...

Ngày tải lên: 11/08/2014, 17:21

... allogeneic stem cell transplantation, severe disease is rare in patients after autologous stem cell transplantation Nevertheless, in patients with severe complications of infections after autologous stem ... in the department of hematology and oncology of the University of Ulm P.S is attending physician in the department of Diagnostic and Interventional Radiology of the University of Ulm Publish with ... Corey L, Kim HW, Huang ML, Nguy L, Boeckh M: Clinical outcomes of human herpesvirus reactivation after hematopoietic stem cell transplantation Clin Infect Dis 2005, 40:932-940 Bissinger AL, Einsele...

Ngày tải lên: 12/08/2014, 04:21

... allogeneic stem cell transplantation, severe disease is rare in patients after autologous stem cell transplantation Nevertheless, in patients with severe complications of infections after autologous stem ... in the department of hematology and oncology of the University of Ulm P.S is attending physician in the department of Diagnostic and Interventional Radiology of the University of Ulm Publish with ... Corey L, Kim HW, Huang ML, Nguy L, Boeckh M: Clinical outcomes of human herpesvirus reactivation after hematopoietic stem cell transplantation Clin Infect Dis 2005, 40:932-940 Bissinger AL, Einsele...

Ngày tải lên: 12/08/2014, 04:22

... lysis of these cells This is thought to be the main mode of action of NK cells [81-86] Natural killer cell alloreactivity in hematopoietic stem cell transplantation The clinical significance of ... editions of InTech Books and Journals can be found at www.intechopen.com Contents Preface VII Section Basic Aspects of Stem Cell Transplantation Chapter Immunogenetics of Hematopoietic Stem Cell Transplantation ... long-term antileukemic effect of unmodified allogeneic hematopoietic Immunogenetics of Hematopoietic Stem Cell Transplantation http://dx.doi.org/10.5772/54281 stem cell transplantation in patients...

Ngày tải lên: 18/02/2014, 04:20

... Chapter 11 Sources of Hematopoietic Stem Cells 199 Piotr Rzepecki, Sylwia Oborska and Krzysztof Gawroński Chapter 12 Cryopreservation of Hematopoietic and Non -Hematopoietic Stem Cells – A Review ... Relationships of Collagen Extracellular Matrices on Cardiac Differentiation of Human Mesenchymal Stem Cells 183 Pearly Yong, Ling Qian, YingYing Chung and Winston Shim Clinical Aspects of Stem Cell Transplantation ... Basic Aspects of Stem Cell Transplantation Chapter Generation of Patient Specific Stem Cells: A Human Model System Stina Simonsson, Cecilia Borestrom and Julia Asp Chapter Importance of Non-HLA...

Ngày tải lên: 20/02/2014, 08:20

... antigens define mature subpopulations of cells, such as erythrocytes, T cells, B cells, NK cells, monocytes, and granulocytes The degree of enrichment of stem cells offered by such “lineage depletion” ... The very low frequency (

Ngày tải lên: 11/04/2014, 09:45

... characteristics of stem cells: (A), Symmetric cell division leads to self-renewal of stem cells; (B), Asymmetric cell division leads to replacement of the stem cell and production of a sister cell, exemplified ... by transplants of blood stem cells for other diseases showed remission of their MS symptoms In a clinical trial of hematopoietic stem cell (HSC) transplantation for MS, twenty out of twenty-six ... that modified stem cells could be used in cell therapy for Parkinson’s disease 42 Therapeutic Uses of Stem Cells But, as with other proposed stem- cell therapies, an autologous source of cells that...

Ngày tải lên: 11/06/2014, 12:52

... Part Hematopoietic Stem Cell Therapy 345 Chapter 16 Hematopoietic Stem Cells Therapeutic Applications 347 Carla McCrave Chapter 17 Hematopoietic Stem Cell Potency for Cellular Therapeutic Transplantation ... small pool of hematopoietic stem cells (HSC) capable of undergoing self-renewal and generating mature progeny of all of the hematopoietic cell lineages To sustain the proper levels of blood cells, ... potential of hematopoietic stem cells J Cell Sci 108: 1–6 Lansdorp, P.M (1997) Self-renewal of stem cells Biol Blood Marrow Transplant 3: 171–178 Lansdorp, P.M (2005) Role of telomerase in Hematopoietic...

Ngày tải lên: 27/06/2014, 13:20