... 42], and ethanol-induced mucosal injury in the upper gastrointestinal tract leading to increase in the permeability of the gut mucosa to endotoxins [43, 44]. These factors are involved in ethanol-induced ... ingestion of ethanol induces a completely different pattern due to the reported ethanol-induced expression and activation of cytokines and chemokines in monocytes and macrophages (including Kupffer ... . Interestingly, HMGN3 has been found to be associated with resistance against anticancer drugs including vinblastine, topotecan, paclitaxel and doxorubincin in human hepatocellular carcinoma...
Ngày tải lên: 31/10/2012, 15:28
... to secondhand smoke, questioning the accuracy of tobacco industry communications, and the declining social acceptability of smoking. Other forms of smoking-relevant advertising include advertisements ... such as packaging, viral marketing, and the Internet; and recent trends in tobacco advertising and promotional expenditures, including the shift from traditional print advertising to promotional ... marketing in the United States, and tobacco marketing remains pervasive and effective in promoting tobacco use. Efforts to curb the depiction of tobacco use in movies have increased in recent...
Ngày tải lên: 06/03/2014, 01:20
báo cáo hóa học:" The role of tendon microcirculation in Achilles and patellar tendinopathy" doc
... ischemia following clamping of the left descending coronary artery and reper-fusion with decreased baseline myocardial oxygen saturation after 15 and 30 min of ischemia indicating an ischemia-induced ... saturation (SO2%) following 5 min (red), 15 min (yellow) and 30 min (green) of ischemia following clamping of the left descending coronary artery and reper- fusion with decreased baseline myocardial ... Kristoffersen-Wiberg M, Svensson L, Aspelin P, Movin T: Eccentric training of the gastrocnemius-soleus complex in chronic Achilles tendinopathy results in decreased tendon volume and intratendinous...
Ngày tải lên: 20/06/2014, 01:20
Chapter 091. Benign and Malignant Diseases of the Prostate (Part 1) pps
... 91. Benign and Malignant Diseases of the Prostate Benign and Malignant Diseases of the Prostate: Introduction Benign and malignant changes in the prostate increase with age. Autopsies of men ... circulating androgen, is converted by the enzyme 5α- reductase to dihydrotestosterone in the gland. The periurethral portion of the gland increases in size during puberty and after the age of 55 ... of men in the eighth decade of life show hyperplastic changes in >90% and malignant changes in >70% of individuals. The high prevalence of these diseases among the elderly, who often have...
Ngày tải lên: 07/07/2014, 02:20
Chapter 091. Benign and Malignant Diseases of the Prostate (Part 2) pot
... Chapter 091. Benign and Malignant Diseases of the Prostate (Part 2) Diagnosis and Treatment by Clinical State The disease continuum—from the appearance of a preneoplastic and invasive lesion ... DRE. PSA circulates in the blood as an inactive complex with the protease inhibitors α 1 -antichymotrypsin and β 2 -macroglobulin, and it has an estimated half-life in serum of 2–3 days. Levels ... metastases are detectable on imaging studies and the measured level of testosterone in the blood. With this approach, an individual resides in only one state and remains in that state until he has...
Ngày tải lên: 07/07/2014, 02:20
Chapter 091. Benign and Malignant Diseases of the Prostate (Part 3) docx
Ngày tải lên: 07/07/2014, 02:20
Chapter 091. Benign and Malignant Diseases of the Prostate (Part 4) potx
Ngày tải lên: 07/07/2014, 02:20
Chapter 091. Benign and Malignant Diseases of the Prostate (Part 5) pot
Ngày tải lên: 07/07/2014, 02:20
Chapter 091. Benign and Malignant Diseases of the Prostate (Part 6) docx
Ngày tải lên: 07/07/2014, 02:20
Chapter 091. Benign and Malignant Diseases of the Prostate (Part 7) potx
Ngày tải lên: 07/07/2014, 02:20
Chapter 091. Benign and Malignant Diseases of the Prostate (Part 8) docx
Ngày tải lên: 07/07/2014, 02:20
Chapter 091. Benign and Malignant Diseases of the Prostate (Part 9) pdf
Ngày tải lên: 07/07/2014, 02:20
Chapter 091. Benign and Malignant Diseases of the Prostate (Part 11) pdf
Ngày tải lên: 07/07/2014, 02:20
Báo cáo y học: "Role of interleukin-7 in degenerative and inflammatory joint diseases" potx
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "Role of IL-33 in inflammation and disease" docx
Ngày tải lên: 11/08/2014, 03:20
Tài liệu The Role of BCG Vaccine in the Prevention and Control of Tuberculosis in the United States: A Joint Statement by the Advisory Council for the Elimination of Tuberculosis and the Advisory Committee on Immunization Practices docx
... renewed interest in examining the indications for BCG vaccination in the United States included consideration of the wide range of vaccine efficacies deter- mined by clinical trials and estimated in ... preventing pulmonary TB in adoles- cents and adults. These studies also were not useful in determining a) the efficacy of BCG vaccine in HCWs or b) the effects on efficacy of the vaccine strain administered 6 ... and recommendations for the use of BCG vaccine in selected persons, and implementation and surveillance of BCG vaccination. BCG VACCINES BCG vaccines are live vaccines derived from a strain of...
Ngày tải lên: 15/02/2014, 13:20
Tài liệu Báo cáo khoa học: The role of N-glycosylation in the stability, trafficking and GABA-uptake of GABA-transporter 1 Terminal N-glycans facilitate efficient GABA-uptake activity of the GABA transporter pptx
... not the terminal trimming of N-glycans is involved in the regulation of the stability and trafficking of GAT1. It has been reported that a variety of molecular chaperones and folding enzymes assist ... substrate binding process. This provides strong evidence that N-glycans, in particular their terminal structures, are involved in regulating the GABA translocation of GAT1, but not in binding of GAT1 ... ⁄ P i and blocked with 5% bovine serum albumin and 0.1 m glycine in NaCl ⁄ P i for 30 min and washed with NaCl ⁄ P i again. Polyclonal antibod- ies against GAT1 were used for immunostaining at...
Ngày tải lên: 19/02/2014, 17:20
Enterprise Adjustment and the Role of Bank Credit in Russia: Evidence from a 420 Firm''''s Qualitative Survey pdf
... decreasing for 53% of the sample, it has been increasing for 36%, and has been stable for the remaining 11%. An increase in indebtedness (of 80% in average) is associated with a 14% decrease in production, ... to ô 1 » (increase in indebtedness) by 15 points (33 minus 18), and increases the probability of Expected-Debt to be equal to ô 4 » (not indebted and not going to be) by 13 points (34 minus 21). 6. ... striking feature is indeed that, the probability of declaring profit appears graphically as a function of both real growth and financial discipline - or limited financial and liquidity constraints,...
Ngày tải lên: 06/03/2014, 08:20
Báo cáo khoa học: Enzymes of creatine biosynthesis, arginine and methionine metabolism in normal and malignant cells Soumen Bera1, Theo Wallimann2, Subhankar Ray1 and Manju Ray1 potx
... of proline and ornithine. J Biol Chem 199, 91–95. 45 Van Pilsum JF, Martin RP, Kito E & Hess J (1956) Determination of creatine, creatinine, arginine, guanidi- noacetic acid, guanidine, and ... the low levels of creatine kinase in the same malignant cells do not appear to be sufficient for the building up of an effective creatine ⁄ phosphocreatine pool. Instead of supporting creatine biosynthesis, ... homo- cysteine to methionine. Tissue metabolism of arginine and methionine is of high importance for the effective regulation of cell death and survival in normal as well as in tumor cells. Polyamines...
Ngày tải lên: 07/03/2014, 04:20
Báo cáo khóa học: Mutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase docx
... mechanistic roles of several of these residues are not described well and there is no example of mutational analysis of all of these residues in the same enzyme. To obtain an insight into how the ... ChiB for allosamidin, which is an analogue of the proposed oxazolinium ion intermediate [32]. The minor (or even positive) effects of Y214F on substrate and intermediate binding and the large negative ... 30.1 a The kinetic parameters of Y10F could not be measured at pH 9.0 due to enzyme instability. At pH 8.0 Y10F showed a k cat of 0.55 and K m of 47.2 (compared to a k cat of 3.5 and a K m of 24.9 in...
Ngày tải lên: 07/03/2014, 14:20