... types and it is the characteristics of this situation type that influence the forms of language that realize the genre So the context of situation (register) is the second aspect of social context ... Aims of the study This study aims to investigate the characteristics of metaphor in poetry from a systemic functional perspective The objective of the study is: - To examine the characteristics of ... 12) in terms of the variables of Field, Tenor and Mode + The FIELD OF DISCOURSE concerns what is happening, to the nature of the social action that is taking place: what is it that the participants...
Ngày tải lên: 07/11/2012, 14:44
... that the number of student drop-outs will minimising.Besides, the ministry also encouraged teacher to change the method of teaching - SUPPORTING STUDENTS IN DISADVANTAGED AREAS The Ministry of ... Ngoc, head of the Department of Information 11 and Technology under the Ministry of Education and Training The development and application of ICT was an essential part of reforming the national ... first five years of operation, universities will not have to pay tax, while they will pay 5% in tax in the 6-9 th years, while the full tax of 10% will be imposed as of the 10th year of operation...
Ngày tải lên: 19/07/2013, 16:34
Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf
... (Fig 5B) The ER is the site of synthesis of all secretory proteins and resident proteins of the membrane system, and any perturbation that compromises the proteinfolding capacity of the organelle ... TAG synthesis It is suggested that the creation of a pool of oversaturated lipid intermediates makes these molecules inaccessible to the enzymes of TAG synthesis, whereas a certain degree of unsaturation ... point), is the main cause of toxicity This proposal, however, is not consistent with the disappearance of lipid droplets from stearate-treated cells, as observed in this investigation (Fig 5B) The...
Ngày tải lên: 14/02/2014, 22:20
Tài liệu SWIMMING IN SEWAGE: The Growing Problem of Sewage Pollution and How the Bush Administration Is Putting Our Health and Environment at Risk ppt
... sewage is discharged, dissolved oxygen is depleted faster than it can be replenished by photosynthesis, wave action, or other natural means The microorganisms instead deplete the oxygen of the receiving ... some of the major cities of the Midwest Yet the distance between wastewater discharges and water supply intakes is often very short In Michigan, for example, the distance between wastewater discharge ... communities, as is the case for most of the interior portions of the United States, sewage overflows can put downstream users at risk The Missouri River, for instance, is the source of drinking water...
Ngày tải lên: 17/02/2014, 10:20
Tài liệu Báo cáo khoa học: The thioredoxin-independent isoform of chloroplastic glyceraldehyde-3-phosphate dehydrogenase is selectively regulated by glutathionylation docx
... [20] On the other hand, the activity of the purified recombinant C153S mutant was similar to that of the wild-type protein (data not shown), and the kinetics of inactivation in the presence of mm ... +dithiothreitol C Discussion The aims of the present study were to establish whether chloroplastic GAPDH isoforms undergo glutathionylation and thiol oxidation, and to examine the effect of these modifications ... oxidation By contrast, the results of the present study show that AnBn GAPDH isoforms, representing the major isoforms of photosynthetic GAPDH in chloroplasts of higher plants, though being sensitive...
Ngày tải lên: 19/02/2014, 05:20
“Marketing is the whole business, taken from the customer’s point of view.” - Peter Drucker docx
... Beginning with the farmer’s connection with the land; if care is not exercised, the land may lose productivity The vendor is in partnership with the market; and again, if care is not exercised, productivity ... market The trend in this type of communication is the e-newsletter delivered via email Many companies offer e-newsletter services with affordable rates based on the number of subscribers on your list ... personnel-find out if the food section editor is interested in a recipe of the week, see if the garden writer needs leads on the new and hot perennials •When someone from the media contacts you offer, “How...
Ngày tải lên: 06/03/2014, 21:20
Báo cáo khoa học: N-Glycosylation is important for the correct intracellular localization of HFE and its ability to decrease cell surface transferrin binding pptx
... The effect of HFE binding to TfR1 is to lower the affinity of the receptor for transferrin [15] This most likely reflects the existence of overlapping HFE and transferrin-binding sites on the receptor ... this way, and despite the overall importance of glycosylation, our results nevertheless argue against the existence of a single glycosylation site that is of such absolute importance that it is ... We propose that glycosylation is important for the folding of HFE and is essential for transport and exit of the protein from the ER The importance of glycosylation is cumulative, however, with...
Ngày tải lên: 06/03/2014, 22:21
Báo cáo khoa học: The F13 residue is critical for interaction among the coat protein subunits of papaya mosaic virus doc
... among the CP subunits monomeric form of the protein [10] This protein failed to assemble, form disks or interact with RNA in vitro [10] On the basis of this result, we hypothesized that the N-terminus ... CP F13 Therefore, on the basis of our results, it is likely that a deletion of 32 amino acids will be tolerated by PVX without disturbing the assembly process Alignment of this F residue is also ... in the PapMV CP Therefore, on the basis of the alignment, we propose that a hydrophobic residue at the position that corresponds to PapMV CP F13 is preferred in half of the potexvirus CP It is...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: Structure of Streptococcus agalactiae serine⁄threonine phosphatase The subdomain conformation is coupled to the binding of a third metal ion pptx
... to the mechanism of the enzyme (see Discussion) 3132 Discussion Overall structure The structure of SaSTP is very similar to that of ˚ MtSTP, with an rmsd ⁄ Ca of 1.8 A overall (Table 1) All the ... in the active site of a PPM ⁄ PP2C STP and a flap domain conformation very different to that in HsSTP [9] This raises the question of whether the difference in conformation of the flap domain is ... so the fact that mutations at the M3 site not change kcat is unsurprising There is probably no change in active site contents The WH in prokaryotic enzymes is located on the opposite side of the...
Ngày tải lên: 07/03/2014, 09:20
Báo cáo khoa học: Epl1, the major secreted protein of Hypocrea atroviridis on glucose, is a member of a strongly conserved protein family comprising plant defense response elicitors potx
... knowledge about the ability of Hypocrea ⁄ Trichoderma spp to induce defense responses in a variety of plants, the molecular basis of this mechanism is still unclear and the number of identified elicitors ... agent of the human respiratory disease San Joaquin Valley fever, was proposed as a Coccidioidesspecific antigen for the diagnosis of this fungus [30,31] The restricted description of members of the ... 32]+) Although the information content of the PMF based on the number of detected peptides was high with respect to the size of the protein (five detected peptides out of seven theoretical peptides),...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: Cellular refractoriness to the heat-stable enterotoxin peptide is associated with alterations in levels of the differentially glycosylated forms of guanylyl cyclase C pdf
... internalization of the 145 kDa form through endocytosis and subsequent degradation The mechanisms involved in this process are not yet identified It is possible that the activation of the cyclase domain of the ... modification of the a-1,6 arm of the mannose residues was essential to allow formation of the 145 kDa form of GC-C and ligand responsiveness Western blot analysis of cells cultured in the presence of swainsonine ... amount of 130 kDa protein was localized on the surface of The studies described in this report suggest that regulation of the glycosylation of GC-C can act as a means of controlling the ability of...
Ngày tải lên: 08/03/2014, 08:20
Báo cáo Y học: Mammalian HSP60 is quickly sorted into the mitochondria under conditions of dehydration docx
... conditions In the present study, we observed the import of the protein into the mitochondria of the water-restricted rat kidneys The osmotic pressure increased in the rat kidney In the kidney, there ... together, these results indicate that the mammalian HSP60 is localized in both the cytoplasm and the mitochondria in almost the same amounts There are few reports concerning the import system of ... localization of HSP60 is not changed These sections are either less- or are unaffected by the osmotic stress, and the quantity and localization of HSP60 in the cytoplasm and mitochondria of these sections...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo khoa học: N-Methylation in polylegionaminic acid is associated with the phase-variable epitope of Legionella pneumophila serogroup 1 lipopolysaccharide pptx
... was the highest compared to other pools from the same strain Therefore, further structural investigation was performed with this preparation The 1H NMR chemical shifts and the grouping of the ... calculate the average chain-length of the PSNH4OH/HF and the distribution of N-methylated legionaminic acid derivatives The signal of a-L-RhaII H1 (dH 4.99) in the ® 3)-a-L-RhaII-(1 ® 3)-LRhaI disaccharide ... Therefore, there is a strong indication for the location of the N-methylated legionaminic acid residue proximal to the LPS core oligosaccharide, though its location at any other position of the...
Ngày tải lên: 08/03/2014, 10:20
The Female Brain is one of the most-talked-about books of the year. ppt
... conflict, or displays of status They often express agreement with a partner’s suggestions And when they have ideas of their own, they’ll put them in the form of questions, such as “I’ll be the teacher, ... destroyed whatever Leila and the other girls were making Boys will this to one another—they are not concerned about the risk of conflict Competition is part of their makeup And they routinely ignore ... response The girls will think that if they it just right, they’ll get the reaction they expect It’s the same kind of instinct that keeps a grown woman going after a narcissistic or otherwise emotionally...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo khoa học: A region within the C-terminal domain of Ure2p is shown to interact with the molecular chaperone Ssa1p by the use of cross-linkers and mass spectrometry doc
... peptides This model was built from the X-ray structure of the C-terminal domain of Ure2p and integrates the finding that the N-terminal domain of Ure2p is flexible An enlargement of the region of Ure2p ... within the same area in the 3D structure of Ure2p Thus, the binding of Ssa1p to the region centered on lysine 339 could abolish the acquisition by Ure2p of an assembly competent state The results ... species, were observed in the presence of ATP No change in the mobility of the Ure2p–Ssa1p complexes was detected in the presence of ATP The stoichiometry of Ure2p and Ssa1p within the 120 and 160 kDa...
Ngày tải lên: 15/03/2014, 00:20
Báo cáo khoa học: b-Secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins pot
... levels altered the ratio of APPsa to APPsb, but did not substantially modify the total levels of APPs or of APP CTFs This suggests that there is a discrete pool of FLAPP that is directed towards ... in human APP (Table 1), whereas the absence of this band in the APP KO extract confirms the specificity of this band as a true APPs species (Fig 1C) The levels of this APPsa band were dramatically ... which recognizes the N-terminus of APP, the polyclonal antiserum C8, which recognizes the C-terminus of APP, and the polyclonal antiserum D2-II, which recognizes the ectodomain of APLP2 (Calbiochem,...
Ngày tải lên: 15/03/2014, 10:20
Statute Prevents State Agencies From Considering Community Benefits When Granting Tax‑Exempt Status, While the Effects of Purchases and Consolidations on Prices of Care Are Uncertain ppt
... understand what they consider as costs of uncompensated care and how they calculate the costs To the extent possible, examine whether the purchases of nonprofit hospitals and the consolidations of community ... Members of the Legislature Office of the Lieutenant Governor Little Hoover Commission Department of Finance Attorney General State Controller State Treasurer Legislative Analyst Senate Office of Research ... Hospitals (Schedule H) The purpose of this schedule is to provide information on the activities and policies of, as well as the community benefits provided by, the nonprofit hospitals The schedule specifically...
Ngày tải lên: 15/03/2014, 23:20