risks associated with the development of cervical cancer

... modernization associated with the development of the knowledge-based economy in the Province of Thua Thien Hue in the near future. 2.2. Research tasks With the above objectives, the thesis has the following ... material wealth and the spirit of service to society. With this approach of the thesis, the concept of human resources fully reflects the aspects: 1) The quantity criteria of human resources, ... growth of the capacity to endure the pressure of work and creative energy as well as the structure of the labor force must be consistent with the growth rate of technical infrastructure and the...

Ngày tải lên: 22/07/2014, 18:29

... such as the mesothelium, the coelomic epithelium of the ovary, the nonpigmented epithelium of ciliary processes, the d istal convoluted tubule of the kidney, and the choroid plexus of the brain. All ... Immunohistochemical expression of CA12 was highly associated with the histologic grade of cervical cancer. Lack of CA12 expression was associated with PD histology, with an odds ratio of 3.9 (P = 0.01). ... 4). Discussion Inourstudy,wediscoveredthatCA12expressionwas strongly associated with histologic grades of the cervical cancer. As CA12 and histologic grade were significantly associated with each other, we then examined whether an applica tion of combined...

Ngày tải lên: 09/08/2014, 09:20

... None of the patients, independently of the tumor site, age, the abuse of predisposing carcinogens, or the presence of other kinds of tumors, carried the CHK2 1100delC variant. Conclusions: The ... impact on the development of SCCHN. Background Hea d and neck cancer is the fifth most common cancer in the world [1]. The tumor suppressor p53 is strongly involved in the carcinogenesis of these ... analysis of exon 10 of the CHK2 gene was performed for all patients. However, none of the patients showed the presence of the 1100delC variant. Discussion None of the investigated 91 patients with...

Ngày tải lên: 11/08/2014, 07:21

... congruent with the definition of each of the subtypes. These results are consistent with the clinical profile definitions of burnout syndrome. In addition, they assist the recognition of distinct profiles ... and that the “worn-out” profile is asso- ciated with the cumulative effect over time of the characteristics of an organisation. The recognition of these variables will assist the process of clinical ... clinical profiles. We h ave seen that the “frenetic” profile is highly associated with the number of hours per week dedicated to work, that the “underchallenged” profile is related with the type of occupation...

Ngày tải lên: 11/08/2014, 15:22

Ngày tải lên: 12/08/2014, 13:22

Ngày tải lên: 14/08/2014, 07:21

Ngày tải lên: 14/08/2014, 07:21

... revealed that over-expression of the three proteins was signifi- cantly associated with the genesis and progression of CRC. The functional implications of the alterations in the levels of these proteins are ... role in the development and progression of CRC. Further functional and clinical analysis of the proteins is necessary to elucidate their precise role in the process of CRC and the formation of metastases. Experimental ... prognostic variables. The evaluation of carcino- embryonic antigen in serum has not fulfilled the prom- ise of a simple test that would offer early diagnosis of colon cancer. A number of other, less well-explored, potential...

Ngày tải lên: 23/03/2014, 03:20

... 4 genotype frequency and ORs of the Gab1 genotypes for gastric cancer among the seropositive subjects. The Gab1 gene was not associated with the risk of gastric cancer among the seropositive subjects. ... all gastric cancer cases had evidence of H. pylori infection because of the earlier presentation or diagnosis of cancer. In summary, the Gab1 A/A was associated with the low risk of H. pylori ... G/G of the PTPN11 gene encoding SHP-2 increased the risk of gastric atrophy among the seropositive subjects [18]. The present study examined the association of a polymorphism of Gab1 with...

Ngày tải lên: 31/10/2012, 15:37

... preconditions the power of the pre- sented results for the -173 G/C SNP and the -794 (CATT) n microsatellite was 98% and 87%, respectively. The linkage disequilibrium of the two loci was assessed with the ... Table 3 shows the genotype and allele distribution of both polymor- phisms in the three groups. The carriage of the allele - 173C was significantly associated with carriage of the -794 CATT 7 ... on the fraction of non-surviving patients and on the genotype relative risks the statistical power of the significant associations were 81%, 96% and 91%, respectively. The relative risks of -173...

Ngày tải lên: 18/06/2014, 15:20

... pills support the role of capsaicin in the development of coronary vasospasm through increased sympathetic stimulation. Conclusions This is the first report linking the use of cayenne pepper ... myocytes, an effect that is associated with the inhibition of potassium currents [8,9]. Coronary vasospasm and acute myocardial infarction (AMI) associated with the use of topical capsaicin patches ... one of the few cases associated with capsaicin. Capsaicin, a sympathomimetic agent, may be implicated in the initiation of coronary vasospasm and acute myocardial infarction in the absence of...

Ngày tải lên: 20/06/2014, 20:20

... transfer of phVEGF 165 [37]. The hypothesis that VEGF might have dual functions in the pathogenesis of SSc, with positive effects on the vascular system but with negative effects on the development of ... endothelial growth factor Page 1 of 10 (page number not for citation purposes) Disease duration and VEGF levels To examine whether the upregulation of VEGF is a feature of the early stages of the ... [41]. The inverse association of endostatin with giant capillaries and microhemorrhages and of the higher levels of endo- statin in patients with avascular areas argue for a role of endostatin in the...

Ngày tải lên: 09/08/2014, 06:22

... to the loss of disc collagen and GAGs. The lack of effect on GAG synthesis further validates the importance of the degradative component of the remodeling cycle in relaxin's modulation of ... determined the effects of relaxin with or without β-estradiol on the modulation of MMPs in joint fibrocartilaginous explants, and assessed the contribution of these proteinases to the loss of collagen ... tissue. In this study we determined the effects of relaxin with or without β-estradiol on the modulation of MMPs, and assessed the contribution of these proteinases to the changes in collagen and glycosaminoglycan...

Ngày tải lên: 09/08/2014, 06:22

... the topographical loss of cartilage in the different subregions of the knee and the associated risk factors. Moreover, the impact of the location and rate of cartilage loss on the evolution of ... time as the disease progressed. The relationship between the worsening in the WOMAC scores with the loss of cartilage on the central portion of the tibial plateau is intrigu- ing. The level of significance ... predictors of the loss of cartilage volume in the central area of the medial femo- ral condyles (Table 4) at baseline were (in order of signifi- cance) the loss of joint space (JSN), the presence of...

Ngày tải lên: 09/08/2014, 10:20

... expressed throughout the entire cardiac crescent early in the developing heart. With the development of the heart, Tbx5 is asymmetrically expressed in the heart. Expression of Tbx5 in the ventricu- Figure ... HDAC activities through the intervention of the transcription of HDAC genes. More likely, valproate inhibits HDAC activi- ties directly by binding with the active site of the enzyme as other HDAC inhibitors ... malformation during heart development. Further studies are on the way to explore the down-stream activities after the valproate- enhanced expression of these transcriptional factors in the developing heart. Conclusion Our...

Ngày tải lên: 10/08/2014, 05:21

... downregulation of E-cadherin in mammary epithelial cells induced an epithelial to mesenchymal transition and showed that this was associated with the acquisition of cancer stem-cell-like properties. They ... agents. Competing interests The author declares that he has no competing interests. References 1. Kaelin WG Jr: The concept of synthetic lethality in the context of anticancer therapy. Nat Rev Cancer 2005, ... capable of selectively killing cancer cells scored in the high-throughput cytotoxicity screens performed over the past 50 years, only to be discarded because they failed one or more of these other...

Ngày tải lên: 11/08/2014, 12:20

Ngày tải lên: 12/08/2014, 18:20

Ngày tải lên: 12/08/2014, 18:20