riskofderm predictions based on in vivo factors

Predicting in vivo anti hepatofibrotic drug efficacy based on in vitro high content analysis

Predicting in vivo anti hepatofibrotic drug efficacy based on in vitro high content analysis

... localization [96], study of protein-protein interactions, and drug screening [97, 98] In order to interpret information captured in images obtained from HCA, numerous efforts have been made using advanced ... combining all data into a single index for ranking We proposed an innovative method for determining the optimized weights for each of the 10 markers of fibrosis in Chapter 1.5.4 In vitro -in vivo ... corresponding in vivo index Ein vivo that were computed from histological scores The result infers that our in vitro cell -based system has some predictability of the in vivo response • In Chapter...

Ngày tải lên: 10/09/2015, 15:48

166 270 0
Báo cáo khoa học: " Correction of patient positioning errors based on in-line cone beam CTs: clinical implementation and first experiences" pptx

Báo cáo khoa học: " Correction of patient positioning errors based on in-line cone beam CTs: clinical implementation and first experiences" pptx

... correction of the transversal components is mainly given by the positioning precision of the table which is +-0.5 mm Additional intrafractional variations also contribute to the remaining error, ... identification and target definition in conformal radiation therapy A well established approach for in- room image acquisition is the use of a conventional CT scanner sharing the same couch with the linear ... 10–12 minutes (table 3) Dealing with rotational errors In this work, we implemented rigid matching (detecting translational and rotational errors) and correction of tranlational errors only into...

Ngày tải lên: 09/08/2014, 10:21

9 286 0
báo cáo khoa học: "Evolutionary relationships based on in the Sativa group of Oryza isozyme data" docx

báo cáo khoa học: "Evolutionary relationships based on in the Sativa group of Oryza isozyme data" docx

... electromorph found only in strains that originated in Surinam However, the electromorph Acp-1.4, that was frequent among American strains was only found in Asia among the strains that originated in Malaysia ... in relation with their differentiation in indica and , KA japonica types (O 1958) Interestingly, the pattern of variation in the wild strains was similar to the main pattern of differentiation ... two strains originating in New Guinea but with an Australian affinity 4) O rufipogon, Australia (AO) 5) O rufipogon, America (AM) 6) O breviligulata in Africa (BV) 7) O longistaminata in Africa...

Ngày tải lên: 09/08/2014, 22:23

26 325 0
Báo cáo khoa học: Diversity of human U2AF splicing factors Based on the EMBO Lecture delivered on 7 July 2005 at the 30th FEBS Congress in Budapest pptx

Báo cáo khoa học: Diversity of human U2AF splicing factors Based on the EMBO Lecture delivered on 7 July 2005 at the 30th FEBS Congress in Budapest pptx

... splicing factors, the U2AF65 protein further contains an arginine and serine rich (RS) domain that is required for spliceosome assembly in vitro [20,21] Importantly, binding of U2AF65 alone is ... U2AF35 in splicing regulation First, loss-of-function mutations in dU2AF38 affected splicing of the pre-mRNA encoding the female-specific RNA-binding protein Sex-lethal [58] Second, depletion of ... coding sequence termination if it contained an in- frame stop codon within an internal exon For the predicted patterns of splicing, there is redundance in the number of accessions shown because...

Ngày tải lên: 23/03/2014, 10:20

10 410 0
ENCAPSULATION OF PLATINUM BASED DERIVATIVES WITHIN CARBON NANOTUBES INVESTIGATIONS ON CONTROLLED RELEASE AND IN VIVO BIODISTRIBUTION

ENCAPSULATION OF PLATINUM BASED DERIVATIVES WITHIN CARBON NANOTUBES INVESTIGATIONS ON CONTROLLED RELEASE AND IN VIVO BIODISTRIBUTION

... humanised monoclonal antibody i.p intraperitoneal i.v intravenous IAP intra-abdominal pressure IC50 half maximal inhibitory concentration ICP-MS inductively coupled plasma mass spectrometry ICP-OES inductively ... loaded on the CNTs by the π-π stacking interaction between its quinine part and nanotubes’ graphitic surface DOX will detach from the carrier in an acidic environment upon internalization into ... images for locating cancer tumors in patients; in addition, surgeons can see the glowing tumor under UV light following the infusion of quantum dots into tumor sites, thus improving the accuracy...

Ngày tải lên: 08/09/2015, 18:10

258 259 0
Báo cáo y học: " Effect of Weight Reduction on Cardiovascular Risk Factors and CD34-positive Cells in Circulatio"

Báo cáo y học: " Effect of Weight Reduction on Cardiovascular Risk Factors and CD34-positive Cells in Circulatio"

... restriction The particular weight loss regimen we examined consisted of severe calorie restriction along with vitamin supplements and administration of human chorionic gonadotropin (hCG), a hormone ... cells in circulation during dieting program was 69% ± 50% In conclusion, the weight loss program analyzed in our study resulted in the improvement of the number of CD34+ cells in circulation and ... plasma concentrations of biochemical markers of inflammation and endothelial activation (C-reactive protein, interleukin -6, soluble adhesion molecules, von Willebrand factor, and endothelin -1)...

Ngày tải lên: 25/10/2012, 10:51

8 594 0
Báo cáo y học: "Gain of a 500-fold sensitivity on an intravital MR Contrast Agent based on an endohedral Gadolinium-Cluster-Fullerene-Conjugate: A new chance in cancer diagnostics"

Báo cáo y học: "Gain of a 500-fold sensitivity on an intravital MR Contrast Agent based on an endohedral Gadolinium-Cluster-Fullerene-Conjugate: A new chance in cancer diagnostics"

... (229 µg) was dissolved in PBS containing 2% DMSO resulting in a concentration of 0.22 mmol/L (0.22 nmol/µL) The stock solution was diluted with Hank’s solution to concentrations of (0.022 mmol/L) ... second intention within this manuscript was to consider the MRI-measurements, described below as a basis for determining MRI tomographical signals in comparison to the commonly used MRI contrast ... solutions as well as Hank’s solution containing 2% DMSO as a control After 25 minutes, the solutions were removed from the cells, then cells were washed twice with Hank’s solution and kept in Hank’s...

Ngày tải lên: 26/10/2012, 09:07

11 656 0
Domestic Wastewater Reclamation Coupled with Biofuel/Biomass Production Based on Microalgae: A Novel Wastewater Treatment Process in the Future

Domestic Wastewater Reclamation Coupled with Biofuel/Biomass Production Based on Microalgae: A Novel Wastewater Treatment Process in the Future

... the one contained in biodiesel produced by microalgal lipid (Lardon et al., 2009), so it is meaningful to recover the energy contained in oil cakes to get the maximum net energy production The ... production based on microalgae cultivation, Eco and Env Sci., 18(3), 1122-1127 (in Chinese) Illman A M., Scragg A H and Shales S W (2000) Increase in Chlorella strains calorific values when grown in ... reclamation Wastewater Artificial wetland Disinfection Primary settled sludge Microalgal cells Organics in high concentration Oil extraction Environmental and landscape reuse Municipal reuse Industrial...

Ngày tải lên: 05/09/2013, 10:17

9 762 0
Web-Based Organizing in Traditional Brick-and-Mortar Companies - The Impact on HR

Web-Based Organizing in Traditional Brick-and-Mortar Companies - The Impact on HR

... Supply chain integration: collaboration throughout the total value chain; and Fully integrated e-business: internal and external integration sharing real-time information (resulting in ‘bricks-and-clicks’ ... headings: • • • the introduction of flexible working practices to meet flexible production requirements; an agile production approach, focusing on minimizing buffers and concentrating on a just -in- time ... downturn both in the world economy in general and in Internet-related stocks in particular — seems inevitable One particular area of growth in B2B transactions is taking place in oldeconomy firms...

Ngày tải lên: 24/10/2013, 08:20

30 543 0
trends in world educational media based on entries to the japan prize since 2000

trends in world educational media based on entries to the japan prize since 2000

... others in a media environment where information spreads around the world in an instant and can have astonishing influence In addition, an increasing number of educational programs and other content ... to confront societal problems and find solutions Teen participation in program production spreading worldwide Participation of teenagers in program planning and reporting has been popular since ... PRIZE In addition to content for school curricula, in recent years, these productions have increasingly focused on nurturing scientific thinking, relaying the important message that science is interesting...

Ngày tải lên: 01/11/2013, 14:44

25 387 0
Financial distress prediction based on OR-CBR in the principleof k-nearest neighbors

Financial distress prediction based on OR-CBR in the principleof k-nearest neighbors

... Wu, D.-S (2005) An application of pattern recognition on scoring Chinese corporations financial conditions based on back propagation neural network Computers & Operations Research, 32(5), 1115–1129 ... H (2005) Case -based reasoning in steel bridge engineering Knowledge -Based Systems, 18(1), 37–46 Watson, I (1999) Case -based reasoning is methodology, not a technology Knowledge -Based Systems, ... While, machine learning models can achieve more accuracy by consuming more time • As shown in Tables 6–9, when carrying on the comparison between Basic CBR and the other models based on leave-one-out...

Ngày tải lên: 23/12/2013, 17:17

17 471 2
A study on culture based activities in developing cross cultural awareness for the first year students at hanoi national economics university

A study on culture based activities in developing cross cultural awareness for the first year students at hanoi national economics university

... teaching is indeed culture teaching and the teaching of culture should become an integral part of foreign language instruction Beyond outlining present English teaching guidelines, culture -based ... learning should be more than the manipulation of syntax and lexicon Regarding teaching culture in language training, it is important to mention the conclusion of Robert Politzer, who says in the ... being used in a situation and then go on to gain an understanding of the cultural factors at work, this is for them one of the most absorbing and exciting parts of any language lesson Studying...

Ngày tải lên: 29/01/2014, 10:33

40 897 3
Tài liệu University Oars Being a Critical Enquiry Into the After Health of the Men Who Rowed in the Oxford and Cambridge Boat-Race, from the Year 1829 to 1869, Based on the Personal Experience of the Rowers Themselves pdf

Tài liệu University Oars Being a Critical Enquiry Into the After Health of the Men Who Rowed in the Oxford and Cambridge Boat-Race, from the Year 1829 to 1869, Based on the Personal Experience of the Rowers Themselves pdf

... Colonies or in other parts of the world, and the only method I could discover of obtaining information regarding several of viil INTRODUCTION them, was to write to persons bearing the same name in this ... of his indisposition (but once when living in damp air) If the induration of the right lung which was observed in A.'s case really commenced at the time he experienced pain in rowing in the College ... devotion to the art of Rowing, acquaintance among old Oars, and success in training some of the most finished University Crews, render any expression of opinion coming from them peculiarly valuable...

Ngày tải lên: 14/02/2014, 21:20

419 542 0
Tài liệu Báo cáo khoa học: Shaped by the environment – adaptation in plants Meeting report based on the presentations at the FEBS Workshop ‘Adaptation Potential in Plants’ 2009 (Vienna, Austria) pdf

Tài liệu Báo cáo khoa học: Shaped by the environment – adaptation in plants Meeting report based on the presentations at the FEBS Workshop ‘Adaptation Potential in Plants’ 2009 (Vienna, Austria) pdf

... results, including novel concepts such as environmentally induced increases in mutation rates in bacteria and a heritable, epigenetic, environmentally-induced switch of pollination syndromes in Mimulus, ... presented research on gene regulons and regulatory pathways involved in freezing tolerance in Arabidopsis Freezing tolerance increases in many plants in response to low, non-freezing temperature, ... results) Fingerprinting -based methods indicate that recurrent allopolyploidy significantly increases gene expression range and methylation variation, resulting in higher levels of evolutionary flexibility...

Ngày tải lên: 18/02/2014, 11:20

10 666 0
The Breast Cancer Epidemic: Modeling and Forecasts Based on Abortion and Other Risk Factors potx

The Breast Cancer Epidemic: Modeling and Forecasts Based on Abortion and Other Risk Factors potx

... (higher fertility) increases protection Breastfeeding gives additional protection Hormonal contraceptives are conducive to breast cancer Hormone replacement therapy (HRT) is also conducive to breast ... fertility in Sweden are shown in Figures and The nonlinear trend in fertility makes modeling difficult The abortion rates in Sweden are higher than in England at the adult ages, but in Sweden ... malignancies in the Czech Republic in 2025 compared to the 5,449 reported for 2003, a 54% increase Finland In Finland cancer registration started in 1953 and data is available for years since 1977 The incidence...

Ngày tải lên: 06/03/2014, 02:21

7 406 0
Proceedings of the International Conference on Evidence Based Practice in Dentistry pptx

Proceedings of the International Conference on Evidence Based Practice in Dentistry pptx

... reassessment of the intervention process Attention is also given to steps in assessing non-randomized population-wide interventions and evidence on oral health promotion based on expert opinion The requirement ... smoking is associated with lower salivary cystatin activity and output of cystatin C during gingival inflammation [72] Cystatins are thought to contribute to maintaining oral health by inhibiting ... much linked to things like living conditions, economic factors, education levels, school routines, work routines, home and leisure routines, social habits, and personal whims and fancies Consider...

Ngày tải lên: 06/03/2014, 12:21

69 408 0
Báo cáo khoa học: " Word Sense Disambiguation in Untagged Text based on Term Weight Learning" ppt

Báo cáo khoa học: " Word Sense Disambiguation in Untagged Text based on Term Weight Learning" ppt

... supervised methods In Proc of the 33rd Annual Meeting of the ACL, pages 189-196 U Zernik 1991 Trainl vs train2: Tagging word senses in corpus In Lexical acquisi- tion: Exploiting on- line resources ... Bruce 1997 Distinguishing word senses in untagged text In Proc of the 2nd Conference on Empirical Methods in Natural Language Processing, pages 197-207 H Schutze 1992 Dimensions of meaning Proc of ... present work They 214 Conclusion In this study, we proposed a method for disambiguating verbal word senses using term weight learning based on similarity -based estimation The results showed that...

Ngày tải lên: 08/03/2014, 21:20

8 316 0
Improving penaeus monodon hatchery practices - manual based on experience in india

Improving penaeus monodon hatchery practices - manual based on experience in india

... 200 ppm povidone iodine solution or 50–100 ppm chlorine solution to disinfect the footwear of each person entering the facility Wash bottles containing 20 ppm povidone iodine solution (or 70 percent ... rounded to allow easy cleaning and efficient disinfecting during preparation Eliminating sources of contamination should be based on strict compliance with SOPs by hatchery personnel Tanks and apparatus ... Maintaining high aeration from the beginning releases the chlorine into the atmosphere, hence reducing its killing ability and may account for the ineffectiveness of current protocols used in India...

Ngày tải lên: 14/03/2014, 11:18

117 579 0
Báo cáo " Landscape ecological planning based on change analysis: A case study of mangrove restoration in Phu Long - Gia Luan area, Cat Ba Archipelago" pot

Báo cáo " Landscape ecological planning based on change analysis: A case study of mangrove restoration in Phu Long - Gia Luan area, Cat Ba Archipelago" pot

... presenting possible mangrove restoration pathways depending on site conditions With this understanding, a conceptual framework was proposed based on restoration principles in study area, including ... pre-existing condition (whether or not this was pristine), and includes “natural restoration” or “recovery” following basic principles of secondary ecological succession Secondary ecological succession ... restoration of mangroves [6], analysis of factors influencing community participation in mangroves restoration [8] In Phu Long - Gia Luan region in particular, some studies have been conducted,...

Ngày tải lên: 14/03/2014, 15:20

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