risk factors that contribute to the development of prostate cancer
Báo cáo y học: "Hedgehog overexpression leads to the formation of prostate cancer stem cells with metastatic property irrespective of androgen receptor expression in the mouse model" pps
... Urology 2003, 62:11-20.6. Bonkhoff H: Role of the basal cells in premalignant changes of the human prostate: a stem cell concept for the development of prostate cancer. Eur Urol 1996, 30:201-205.7. ... cascade of intracellular signalling activations that lead to the binding of downstream transcription factors, e.g., Gli1, Gli2 and Gli3 to their target sequencesand then expression of target ... (Figure 2F to 2J) and CaP (Figure 2K to 2O) of the pCX-shh-IG-injected prostates, in contrast to the almost absence of expression in the vehicle controls(Figure 2A to 2E), except that few basal...
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Báo cáo khoa học: Assessment of telomere length and factors that contribute to its stability potx
... to tumor regression. Therefore, factors that contribute to telomere stability may influence the efficiency of the drugs that have potential in cancer therapy. These factors in rela-tion to telomere length ... are calculated as the ratio of the telomere fluorescence signal (TFS) of the sample to that of the internal control, normalized to the DNA valuesat the G0/G1phase. The use of an internal control ... useful indica-tor of telomerase activity in normal and malignant tissues.Telomere length stability is one of the important factors that contribute to the proliferative capacity of many cancer celltypes;...
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Tài liệu Báo cáo Y học: Bivalent cations and amino-acid composition contribute to the thermostability of Bacillus licheniformis xylose isomerase doc
... Qcontent relates to the enzyme’s functional temperature rangeand that BLXI thermostability is also directly related to the binding of specific metals as cofactors. At the same time, the simple relationship ... temperatures. The lower stability and lower Ea of inactivation of BLXIin the presence of Mg2þreflect the fact that the enzymebinds Mg2þwith lower specificity (the Kact of Mg2þis 10times higher that ... unfolding to the extent that Co2þdoes [39,40]. The Eavalues of BLXI inactivation were calculated for the apoenzyme in the presence and absence of metals(Table 3). The nature of the metal...
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financial risk taking-an intro to the psychology of tr and behav fin - elvin 2004
... for the other side to be convinced they are losers. How long are you willing to give them to stampede out of their positions?10. If they do not stampede out of their positions, what will that ... Financial Risk Taking The purpose of this book is to present a synthesis of contributions to the psychology of financial risk taking (I will use the term “trading” as synonymouswith “financial risk ... disappoint the predominant force?13. What is the likelihood of that happening?14. What is the risk of finding out in a trade?15. Is there enough potential for movement to make the trade worth the risk? These...
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Báo cáo y học: "Interactions between IL-32 and tumor necrosis factor alpha contribute to the exacerbation of immune-inflammatory diseases" ppt
... cells to be one of the important sources of IL-32 in the pathogenesis of inflammatory arthritis. To exam-ine the proinflammatory effects of IL-32 produced by CD4+ Tcells, we transduced the ... inflammatory arthritis and isthought to be an autoimmune disease. Inflammation of the joints results in the destruction of cartilage and bone early in the course of the disease. Although the pathogenesis ... IL-32β. Therefore IL-32β had effects onmacrophages rather on than T cells in vivo, and the in vivoroles of IL-32β were mainly to induce other inflammatorycytokines rather than to activate the...
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Báo cáo y học: " Many LINE1 elements contribute to the transcriptome of human somatic cells" pptx
... compared the expression of the L1 ele-ment to that of the surrounding CD38 gene. We found that, while the abundance of the CD38 transcript is several orders of magnitude higher, the pattern of expression ... action of the RB1 promoter itself contributesdirectly to regulation of the L1. Instead, we hypothesize that transcription of RB1 results in the creation of a region of openchromatin that facilitates ... RACE adaptor. (c) Histogram depicting the distribution of polyadenylation positions of 3' expression tags, relative to the end of the L1. (d) Histogram depicting distribution of 5'...
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Báo cáo y học: "Intraoperative PaO2 is not related to the development of surgical site infections after major cardiac surgery" ppt
... ET had full access to all of the study data and takes responsibility for the integrity of the data and the accuracy of the data analysis. Both authorscontributed equally to the study. Study concept ... hours postoperatively.Their findings suggested that perioperative hyperoxiawas not effective in reducing SSIs. These report s add to the evidence base surrounding the potential role of highFIO2in ... used to define SSIs. The SPSS softwarepackage (version 15) was used for statistical analysis.A p ≤ 0.05 was considered significant. To assess risk factors for SSI, we used one-way analysisof...
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báo cáo khoa học: "Factors that contribute to long-term survival in patients with leukemia not in remission at allogeneic hematopoietic cell transplantation" pot
... selection bias due to the nat-ure of retrospective data. Also, our study was limi ted by the small number of patients, the heterogeneity of the disease, the transplant procedure and the stem cellsource. ... prior history of cGVHD(p = .039). The 5-year survival rates of patients with intermediate &prior history of cGVHD +, poor & prior history of cGVHD +, and poor& prior history of cGVHD ... classified patients accordi ng to signifi-cant pre-transplant factors including poor -risk cytoge-netics, number of BM blasts, or secondary leukemia andtheir prior history of cGVHD at 6 months post-trans-plant....
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INTENSIVE LIFESTYLE CHANGES MAY AFFECT THE PROGRESSION OF PROSTATE CANCER docx
... and LNCaP cell growth adds to the strength of evidence.While the evidence linking the effects of diet and lifestyle on the development and progression of prostate cancer is not conclusive, itis ... Cardiovascular disease is the leading cause of death of men and women in the United States andeither the primary or secondary cause of death of most men with prostate cancer, and obesity is of widespread ... lifestyle may reduce the risk of prostate cancer and may affect its rate of progression. Since there isa significant rate of recurrence following any conventional treatmentfor prostate cancer, our findings...
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scientific american - 1994 04 - the dilemmas of prostate cancer
... looting of the Sic‡n tombs, no other assemblage of this type is known to have survived the melting-pot fate of most of the stolen arti-facts. The Sic‡ns ßourished before the Incas,from A.D. 700 to ... crest of a CDW being stuck at a de-fect. If we move the CDW, the marbleclimbs over the edge of the eggcup andfalls into the next one, which means that the next crest of the CDW getsstuck at the ... the AnthropologicalSociety of Washington, showed that the work of Ramon y Cajal and others indi-cated that protoplasm is not merely the physical basis of life, but is the physi-cal basis of...
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Báo cáo y học: "A 12 Week, Open Label, Phase I/IIa Study Using Apatone® for the Treatment of Prostate Cancer Patients Who Have Failed Standard Therapy" pps
... Apatone, Cancer Introduction The PSA era has led to a stage migration in the clinical course of prostate cancer. While this success has dramatically lowered the death rate from prostate cancer, ... marrow toxicity, changes in organ weight or pathologic changes of these organs.9 The purpose of this study was to evaluate the safety and efficacy of oral Apatone administered throughout the ... 6.58 Increased Following the 12 week trial, 15 of 17 patients opted to continue Apatone therapy. Any decision to remain on Apatone therapy was left entirely to the patient. Anecdotally,...
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Risk Factors Affecting the Development of Tuberculosis Infection and Disease in Household Contacts of Patients with Pulmonary Tuberculosis pptx
... [16]. They divided the contact per-sons into 3 groups. The first group consisted of close familyand friends, the second of classmates and teachers and the third of more distant contacts. They ... All of the contacts were comprised of household contacts. Household contacts included spou-se, child, mother-father, brother/sister and other parentsORIGINAL ARTICLETuberculosis Risk Factors ... between TST positivity of contacts and gender, age, closeness to the index case, BCGscar presence and radiological degree of the disease of in-dex case. The rate of TST positivity of household contactsunder...
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Báo cáo sinh học: " Risk factors in the development of stem cell therapy" pdf
... ability to replicate for extended periods of Table 2 Overview of risk factors and risks associated with stem cell-based therapy Risk factors or hazards Identified risksIntrinsic factors - Origin of ... multiple factors may contribute to tumour formation the risk of tumour formation will bedisc ussed along the lines of these individual factors that are discussed in separate paragraphs. Second are the risks ... potential risks and risk factors obtained with other/existing stem cell basedmedicinal products may contribute to the risk evaluation of new stem cell based therapies. The potential risk of tumour...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25