... decrease in the availability of 5-HT, thus contributing to the serotonin-depletion hypothesis of depression Further, 3HK and QUIN are NMDA-receptor agonists High concentrations of these compounds ... throughout the central nervous system In the periphery, they are highly expressed in platelets and many cell types of the cardiovascular system, in fibroblasts, and in neurons of the peripheral ... effect size comparable to that of antidepressants Analyses of the individual items of the BDI showed that significant improvements at week 12 were seen in feelings of guilt, irritability, anhedonia,...
Ngày tải lên: 11/08/2014, 00:23
... The lid to the vessel was sealed to prevent evaporation At the end of the period, the vessel was cooled to room temperature to remove the specimens and the specimens were rinsed in DI water The ... a plot of (ahy)2 as a function of the photon energy of the ZnO thin films grown on the ZnO seeded glass substrates in the four different solutions The band gap energy was derived by Fig The cross-sectional ... inhibit the growth of ZnO crystals in the c-axis direction, which results in the formation of hexagonal prism-shaped ZnO rods with a low aspect ratio It seems that Al3þ ions suppress the role of C6H5O3À...
Ngày tải lên: 06/05/2014, 13:23
Báo cáo hóa học: "Reference values and physiological characterization of a specific isolated pig kidney perfusion model" doc
... examine the creatinine clearance used as approximation of the glomerular filtration rate (GFR) The creatinine clearance represents the mathematical product of the U/Pcrea quotient and the urine-flow ... qualify the outcome of the isolated kidney In this respect, considering the nephron's handling of substrates, the tubular reabsorption of sodium is a further prominent mechanism and the fractional ... conditions via the cannulated external jugular vein Organ collecting The pigs of the slaughterhouse groups were electrically stunned and then exsanguinated Then the organs were Page of 13 (page...
Ngày tải lên: 20/06/2014, 00:20
Báo cáo khoa học: "Commissioning and early experience with a new-generation low-energy linear accelerator with advanced delivery and imaging functionalities" doc
... shift in the directions of the center of the phantom: the 2D-2D match was performed to re-align the phantom, checking the proposed shift respect the expected values (step of the test) The remote ... the clinical arena (at the moment with the exclusion of USA, Canada and Japan) by Varian Medical Systems The results of the commissioning tests and of the first period of clinical operation of ... Zhu TC: TG-106 of the Therapy Physics Committee of the AAPM Accelerator beam data commissioning equipment and procedures: report of the TG-106 of the Therapy Physics Committee of the AAPM Med Phys...
Ngày tải lên: 09/08/2014, 09:21
Báo cáo y học: "gA retroperitoneal abscess caused by Haemophilus parainfluenza after endoscopic retrograde cholangiopancreatography and open cholecystectomy with a common bile duct exploration: a case report" ppt
... inhabitant of the mucosal surfaces of the human upper respiratory tract [4] There is a possibility that the patient may have subsequently coughed up and swallowed the H parainfluenza, moving it into the ... subsequently to the retroperitoneal space via a perforation in the performance of the sphincterotomy [1] Our case also involved ERCP with papillotomy, a possible port of entry for the bacterium The common ... the abscess grow any other organism other than H parainfluenza Conclusions Abscesses after open cholecystectomies have been reported to occur in less than 1% of patients [5] The majority of these...
Ngày tải lên: 11/08/2014, 12:20
Báo cáo y học: " A gastrointestinal stromal tumour presenting incidentally with haemorrhage and perforation associated with a Meckel’s diverticulum: a case report" pps
... at the site of the vitelline duct, which in the embryo Figure Resected specimen in cross-section demonstrating the perforated wall of the Meckel’s diverticulum at the superior margin and the ... was a 45 mm nodule at the apex of the diverticulum with the following features: Full thickness tumour of the bowel wall, extending to serosal surfaces (Figure 4) No areas of tumour necrosis Less ... diverticulum The diverticulum is a true diverticulum containing all layers of the intestinal wall and most commonly arises from the antimesenteric aspect of the ileum, proximal to the ileocaecal...
Ngày tải lên: 11/08/2014, 17:21
Báo cáo y học: "Dialectical Behavioral Therapy for Adolescents (DBT-A): a clinical Trial for Patients with suicidal and self-injurious Behavior and Borderline Symptoms with a one-year Follow-up" pot
... weeks t1 Beginning of therapy t2 Four weeks after the end of therapy t3 One year after the end of therapy Figure Review of the investigation process of the Dialectical Behavioral Therapy for Adolescents ... This hypothesis is also based on the improvement of both the Global Level of Functioning and the reduction of the need for treatment as assessed by the therapist Patients dropping out of therapy ... from the start of therapy to one year after therapy Assessment by the parents showed an improvement of the quality of life, both during therapy, and in the year following therapy Symptoms of psychopathology...
Ngày tải lên: 13/08/2014, 18:21
Báo cáo y học: "Blunt traumatic pericardial rupture and cardiac herniation with a penetrating twist: two case reports" ppt
... herniation of abdominal contents into the pericardial sac Clarke et al, one of the largest reviews to date, included a review of 132 cases plus 10 further cases of their own [3] They found the superior/left/right ... The patient underwent a clamshell thoracotomy where a 10 cm tear in the right of the pericardium (along the path of the phrenic nerve) was noted with a cardiac herniation through the defect The ... demonstrating most of the axial findings including the prominent pneumopericardium and displacement of the heart into the right hemithorax Figure is also distinctly the radiograph showing the diaphragm;...
Ngày tải lên: 13/08/2014, 23:21
money and trade considered, with a proposal for supplying the nation with money
... encreases, the Credit of the Bank encreases, and the Sum of Notes out is greater; And so far from making the People less sensible of the condition of the Country, a surer Judgment of the state of Trade ... with the same kind of goods from other places, or might supply the use of them with goods of another kind; or might consume less of them; yet, that ought not to hinder such a Regulation of the ... Consumption of other Goods; or to supply themselves, they would turn the Land to the product of the several Goods they had occasion for; tho only proper to produce of one kind So, much of the Land...
Ngày tải lên: 05/11/2014, 09:13
The herpetofauna of the peruvian dry forest along the andean valley of the marañón river and its tributaries, with a focus on endemic iguanians, geckos and tegus
... junction with the Rio Chinchipe Located near the Rio Marañon, to the West of the river Located near the Rio Marañon, to the West of the river Located near the Rio Marañon, to the West of the river ... near the Rio Marañon on both sides of the river Located near the Rio Marañon, to the East of the river Located to the East of the Rio Marañon close to the junction with Rio Parcoy BIODIVERSITY OF ... al 2004) The first zoological survey of some parts of the inter-Andean dry forest was the Harvard Peruvian Expedition of 1916, conducted by the Museum of Comparative Zoology (MCZ) of the Havard...
Ngày tải lên: 19/11/2015, 15:51
Báo cáo khoa học: Structural and biological effects of a b2- or b3-amino acid insertion in a peptide Application to molecular recognition of substance P by the neurokinin-1 receptor ppt
... structures of the b-amino acids that best fit are shown in Fig They all correspond to gauche(+) values of the h angle The methyl group of b2-HAla occupies a position close to that of CH2b of Pro or the ... w) values of the selected Pro conformer are ()72°, 153°) The low-energy conformers of b-HAla generated in the grid calculation have been selected on the basis of the best fit with Pro They correspond ... of a-amino acids) has recently been applied to the syntheses of linear tetrapeptides of somatostatin [20] and of cyclic tetrapeptide and pentapeptide analogues of the RGD sequence [19] With the...
Ngày tải lên: 08/03/2014, 08:20
Báo cáo Y học: Selection of effective antisense oligodeoxynucleotides with a green fluorescent protein-based assay Discovery of selective and potent inhibitors of glutathione S-transferase Mu expression doc
... c The number of mismatches in the corresponding region of the nontargeted isoform are given Mismatches are underlined in the sequence Determination of the concentration/activity profile of the ... EGFP-based selection of antisense sequences (Eur J Biochem 269) 2577 activity of the GSTM2-2 protein towards CDNB compared with the activity of the GSTM1-1 protein [22] The size of the fusion proteins ... GSTM1, was another nonspecific inhibitor of EGFP expression as the IC50 values for inhibition of EGFP expression and of EGFP–M1 were both in the same range Analysis of the effect of AS-ODNs on...
Ngày tải lên: 31/03/2014, 15:20
Báo cáo hóa học: " Comparison of three rapamycin dosing schedules in A/J Tsc2+/- mice and improved survival with angiogenesis inhibitor or asparaginase treatment in mice with subcutaneous tuberous sclerosis related tumors" docx
... in the rapamycin treated cohorts and there was no difference in the average weights of the untreated month and 12 month cohorts (see Additional File 3) Although the average weight of one of the ... months of age Additionally, these data show a significant increase with age in both the score per kidney and the number of cystadenomas per kidney for the A/J Tsc2+/strain Furthermore, the tumor ... catalyzes the hydrolysis of L-asparagine to L-aspartic acid and is used as part of the curative combination chemotherapy regimen for the treatment of acute lymphoblastic leukemia (ALL) [36] The anti-tumor...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo sinh học: "Gene therapy with tumor-specific promoter mediated suicide gene plus IL-12 gene enhanced tumor inhibition and prolonged host survival in a murine model of Lewis lung carcinoma" pptx
... HRP/IAA gene therapy Another major focus of the present study was to evaluate whether suicide gene therapy plus immuno-gene therapy had any Page of 10 toxicity on the treated animals The results showed ... up-regulated in the majority of human tumors from all tissues, which prompted the investigations on the use of hTERT promoter to restrict the expression of delivered genes to cancer cells and the results ... effect of gene therapy The LLC mouse model was used to assess the in vivo antitumor activity of AdhTERTHRP and AdCMVmIL-12 as single agent or in combination First of all, the expression of HRP...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học: " The possible link between the elevated serum levels of neurokinin A and anti-ribosomal P protein antibodies in children with autism" pot
... [11-17] There is also an increase in the frequency of autoimmune disorders among autistic families [18-23] Inspite of the fact that the origins of autoimmunity in autism are unknown, the major ... to the degree of the severity of autism However, it is not easy to determine whether the increase in serum neurokinin A levels is a mere consequence of autism or has a pathogenic role in the ... crossreacting antigens in the environment resulting in the release of some self antigens These antigens may result in the induction of autoimmune reactions through the activation of inflammatory cells...
Ngày tải lên: 19/06/2014, 22:20
Báo cáo hóa học: " Nucleotide mismatches between the VP7 gene and the primer are associated with genotyping failure of a specific lineage from G1 rotavirus strains" potx
... was reported that the accumulation of point mutations in VP4 and VP7 genes was the main cause of the failure of the G or P-typing of rotavirus strains [7,8,12,16-21] At least, there are four multiplex ... out of 121 G1 strains from lineage I showed the four specific mismatches at the 5' end of the 9T1-1 primer This was associated with the failure of genotyping of G1 strains from Bangladesh Two of ... ❍; three out of the four mutations by ■, and three mutations plus others at the primer binding site by ᮀ The open branches indicate one or two mutations at the primer binding site The lineages...
Ngày tải lên: 20/06/2014, 01:20
báo cáo hóa học:" Gene therapy with tumor-specific promoter mediated suicide gene plus IL-12 gene enhanced tumor inhibition and prolonged host survival in a murine model of Lewis lung carcinoma" doc
... HRP/IAA gene therapy Another major focus of the present study was to evaluate whether suicide gene therapy plus immuno-gene therapy had any Page of 10 toxicity on the treated animals The results showed ... up-regulated in the majority of human tumors from all tissues, which prompted the investigations on the use of hTERT promoter to restrict the expression of delivered genes to cancer cells and the results ... effect of gene therapy The LLC mouse model was used to assess the in vivo antitumor activity of AdhTERTHRP and AdCMVmIL-12 as single agent or in combination First of all, the expression of HRP...
Ngày tải lên: 20/06/2014, 03:20
Báo cáo toán học: "Positive cones and $L^p$-spaces associated with a von Neumann algebra " pptx
Ngày tải lên: 05/08/2014, 10:20
Báo cáo y học: "Validation of a specific measure to assess healthrelated quality of life in patients with schizophrenia and bipolar disorder: the ‘Tolerability and quality of life’ (TOOL) questionnaire" doc
... in these multidimensional scales we used the unweighted scores In both cases, the higher the scores, the better the HRQoL, and vice versa (2) The Spanish version of the TOOL questionnaire The ... used in these comparisons considering the skewed distribution of data Reliability The internal consistency of the questionnaire was analysed using Cronbach’s a Test-retest reliability of the scores ... structure of the TOOL questionnaire (eigenvalue = 3.331) (Table 3) This dimension explained 39.1% of the variance The component matrix is shown in Table Furthermore, the reliability of this structure...
Ngày tải lên: 09/08/2014, 01:21