response of p53 hotspot mutants to doxorubicin
Assessment and quantification of foetal electrocardiography and heart rate variability of normal foetuses from early to late gestational periods 4
... advantage of the percent plot is that it gives an indication of the magnitude of the difference with reference to its mean Comparison of novel versus commercial HRV softwares 184 value, independent of ... Nevrokard system, the HF power was >50% of the total power In addition to this, the integration of proper and Comparison of novel versus commercial HRV softwares 201 systematic artifact-correction ... dragged by the cursor to an estimated value of 400 ms (b) on the Nevrokard program Comparison of novel versus commercial HRV softwares 179 This was done by integrating into F-EXTRACT an algorithm...
Ngày tải lên: 15/09/2015, 17:11
Assessment and quantification of foetal electrocardiography and heart rate variability of normal foetuses from early to late gestational periods 3
... Development of a novel HRV software 142 The objectives of F-EXTRACT were primarily to automate the extraction of RR-interval data from foetal ECG recorded from FEMO, and to display the power spectra of ... Development of a novel HRV software 140 CHAPTER DEVELOPMENT OF A NOVEL HRV SOFTWARE Development of a novel HRV software 141 Introduction In collaboration with the Computer Science Department of National ... quantification of the activity of the two branches of the autonomic nervous system, which is not possible by the usual foetal heart rate monitoring by cardiotocography The serial follow-up of foetal...
Ngày tải lên: 15/09/2015, 17:11
Assessment and quantification of foetal electrocardiography and heart rate variability of normal foetuses from early to late gestational periods 2
... wave duration (Po to Pt), PR interval (Po to Qo), QRS complex (Qo to St), QT interval (Qo to Tt), and T wave duration (To to Tt) were determined Each fECG recording yielded sets of the above time ... equal to total power of spectral analysis, SDNN reflects total HRV, i.e., all the cyclic components responsible for heart rate variation during the period of recording, such as respiratory, baroreceptor, ... recording divided by the total number of all NN intervals This index is a modified version of the more familiar pNN50, which is defined as the percentage of the number of pairs of adjacent NN intervals...
Ngày tải lên: 15/09/2015, 17:11
Assessment and quantification of foetal electrocardiography and heart rate variability of normal foetuses from early to late gestational periodsb 1
... properties of the feto-maternal interface contribute further to the problem of low signal -to- noise ratio These difficulties are compounded by the sensitivity of the fECG signal amplitude to foetal ... found to be of the same order of magnitude as the conductivity of the overall tissue (0.222 Ω-1 m-1) This, in addition to the small thickness of the membranes (
Ngày tải lên: 15/09/2015, 17:11
Báo cáo hóa học: " Mild hypoglycemia is strongly associated with increased intensive care unit length of stay" pdf
... studies have investigated the impact of hypoglycemia on the cost of care of critically ill patients The purpose of this study was to evaluate the impact of hypoglycemia, defined as BG < 70 mg/dL, ... diagnosis of diabetic ketoacidosis or hyperosmolar nonketotic coma were excluded from the study The glycemic target during the period of the investigation was 80-125 mg/dL Details of the protocol ... control) Per protocol, patients admitted during this period with a diagnosis of diabetic ketoacidosis or hyperosmolar nonketotic coma were not subjected to treatment according to the guideline...
Ngày tải lên: 20/06/2014, 22:20
Báo cáo hóa học: " Reversal of TMS-induced motor twitch by training is associated with a reduction in excitability of the antagonist muscle" ppt
... suprathreshold pulse of Transcranial Magnetic Stimulation (TMS) over the hand area of M1 results in a balance of inhibitory and excitatory processes that leads to an observed twitch of the thumb in ... program (CED Spike 2), then stored into the computer for further off-line analysis EMG activity of the training muscles was continuously monitored during practice to provide visual feedback during ... of Figure (a) Two degree -of- freedom optical goniometer fixed to the dorsum of the wrist to measure deflection produced by TMSinduced twitch in the sagittal and coronal plane; (b) An example of...
Ngày tải lên: 19/06/2014, 08:20
Báo cáo y học: "Tight perioperative glucose control is associated with a reduction in renal impairment and renal failure in non-diabetic cardiac surgical patients" ppsx
... inihibitors 1.4 (0.5 to 3.6) 0.52 12.6 (1.4 to 109.2) 0.02 Transfusion 1.6 (0.5 to 5.9) 0.4 0.7 (0.07 to 7.3) 0.77 Aprotinin 0.7 (0.4 to 1.1) 0.14 2.0 (0.5 to 9.7) 0.39 ACE inihibitors 0.4 (0.3 to ... 0.79 2.3 (0.5 to 11.2) 0.30 ACE inihibitors 1.0 (0.6 to 1.8) 0.94 0.7 (0.2 to 2.8) 0.60 Transfusion 0.9 (0.5 to 1.7) 0.79 0.8 (0.1 to 5.9) 0.69 Aprotinin 0.9 (0.3 to 2.8) 0.94 0.5 (0.2 to 1.4) 0.32 ... Severity Score: to representing a predicted incidence of ARF with dialysis of 0.4%, to representing a predicted incidence of ARF with dialysis of 1.8%, to representing a predicted incidence of ARF with...
Ngày tải lên: 13/08/2014, 11:23
Báo cáo y học: "Vastus medialis cross-sectional area is positively associated with patella cartilage and bone volumes in a pain-free community-based population" pdf
... prospective cohort study of community-based people 40 to 69 years old at recruitment (1990 to 1994) – with the aim of examining the role of lifestyle and genetic factors in the risk of cancer and chronic ... whether the lack of a relationship with cartilage was a true effect or was due to inadequate power of that study is unknown Thus, the aim of this study was to examine the determinants of vastus medialis ... lateralis, cross-sectional area A primary action of the distal portion of vastus medialis is to dynamically restrain the natural tendency of the patella to track laterally [1] Therefore, the relationship...
Ngày tải lên: 09/08/2014, 01:22
Báo cáo khoa học: "bcl-2 expression is not associated with survival in metastatic cutaneous melanoma: A historical cohort study" pptx
... factors in CM The relatively small number of cases analyzed in our study is due mainly to the absence of appropriate protocols for the management of CM in our setting, making it more difficult to ... phase of the cell cycle, although the exact mechanism through which bcl-2 inhibits apoptosis is not fully understood [19] In the presence of bcl-2 overexpression, the ability of the cell to remove ... the sixth and seventh decades of life, with only 22% of the cases diagnosed before the age of 40 [26] We were unable to evaluate the histological characteristics of primary tumors because this...
Ngày tải lên: 09/08/2014, 07:21
Báo cáo y học: "Vastus medialis cross-sectional area is positively associated with patella cartilage and bone volumes in a pain-free community-based population" ppt
... prospective cohort study of community-based people 40 to 69 years old at recruitment (1990 to 1994) – with the aim of examining the role of lifestyle and genetic factors in the risk of cancer and chronic ... whether the lack of a relationship with cartilage was a true effect or was due to inadequate power of that study is unknown Thus, the aim of this study was to examine the determinants of vastus medialis ... lateralis, cross-sectional area A primary action of the distal portion of vastus medialis is to dynamically restrain the natural tendency of the patella to track laterally [1] Therefore, the relationship...
Ngày tải lên: 09/08/2014, 13:22
Báo cáo y học: " The L76V mutation in HIV-1 protease is potentially associated with hypersusceptibility to protease inhibitors Atazanavir and Saquinavir: is there a clinical advantage" potx
... in favour of ATV [18-20] In addition, due to the approval of new drug classes over the past years one might err on the side of caution to supplement therapy regimens with new drugs Due to the low ... http://www.aidsrestherapy.com/content/8/1/7 Page of Table Compensatory changes in virus genotypes within 96 weeks of follow-up therapy Group Patient ID Protease mutations at start of therapy Time of therapy failure Time of 2nd genotype ... of patients was analysed at baseline and week 12, 24, 48 until end of investigation at week 96 to monitor efficiency of therapy Plasma RNA was measured by using the COBAS AMPLICOR HIV-1 Monitor...
Ngày tải lên: 10/08/2014, 05:22
Báo cáo y học: "Anxiety is associated with diminished exercise performance and quality of life in severe emphysema: a cross-sectional study" ppt
... used to be.” It is easy to see that these depression symptoms are also likely to be indicators of COPD severity Thus, it is difficult to conclude that the observed associations between BDI total ... tools However there are published cutoff scores for both instruments to indicate clinically significant symptom levels In general population samples, cutoff scores of 19 and 40 are used for the STAI ... A total of 1218 patients went on to randomization to receive either lung volume reduction surgery or continued regular medical treatment Patients failed to reach randomization for a number of...
Ngày tải lên: 12/08/2014, 11:20
Báo cáo sinh học: "Second chromosome polymorphism of Drosophila buzzatii in a natural population is not associated with gametic selection and does not affect mating pattern" potx
... methodological approaches have been applied to the study of natural selection in nature (see Endler, 1986 for a review) One of them consists of dividing total selection into partial components throughout ... maintenance of polymorphisms However, their conclusions are based on the validity of assumptions; i), random mating; ii), absence of gametic selection; iii), lack of differential attraction of flies to ... chromosomes analyzed, according to Fontdevila et al (1981) Observed karyotypic proportions in the offspring of each cross were compared to those expected by means of goodness of fit X tests The remaining...
Ngày tải lên: 14/08/2014, 20:20
Cumulative inflammatory burden is independently associated with increased arterial stiffness in patients with psoriatic arthritis a prospective study
... count, to 68 (0 to 6) (0 to 8) 0.551 (0 to 3) (0 to 5) 0.248 Swollen joint count, to 66 (0 to 2) (0 to 3) 0.827 (0 to 1) (0 to 1) 0.376 Damaged joint count, to 68 (0 to 3) (0 to 6) 0.118 (0 to 4) ... years 9.2 (2.4 to 14.10) 15.7 (8.5 to 21.2) Tender joint count, to 68 (0 to 8) (0 to 4) 0.033 Swollen joint count, to 66 (0 to 3) (0 to 1) 0.032 Damaged joint count, to 68 (0 to 5) (0 to 6) 0.031 ... to 8) 0.010 Visual analog scale pain, to 100 40 (20 to 60) 50 (30 to 70) 0.212 30 (20 to 50) 30 (20 to 60) 0.964 Patients’ global assessment, to 100 50 (20 to 60) 50 (40 to 60) 0.258 50 (20 to...
Ngày tải lên: 22/09/2015, 15:19
Báo cáo y học: "Elevated plasma homocysteine is positively associated with age independent of C677T mutation of the methylenetetrahydrofolate reductase gene in selected Egyptian subjects"
... consisted of a total of 50 unrelated male patients with past history of myocardial infarction (age ranged between 50-75 years) All patients and controls were living in the same geographic area of Northern ... result of derangement of certain cytokine production? Abbreviations tHcy: total homocysteine; MTHFR: methylenetetrahydrofolate reductase; Gp: Group; CIT: Carotid intimal thickness Conflict of interest ... about the frequency of the MTHFR mutation and its relation to tHcy in the Egyptian population Thus the aim of the present study was to determine tHcy level and its relationship to MTHFR C677T polymorphism...
Ngày tải lên: 03/11/2012, 09:49
Báo cáo y học: "A combination of autoantibodies to cyclic citrullinated peptide (CCP) and HLA-DRB1 locus antigens is strongly associated with future onset of rheumatoid arthritis" potx
... with autoimmune disease: a failure to protect? Rheumatology 2000, 39:1060-1066 Wernhoff P, Olofsson P, Holmdahl R: The genetic control of rheumatoid factor production in a rat model of rheumatoid ... medical centre for rheumatology in the county of Västerbotten), and with a known date of onset of symptoms or signs of joint disease, was coanalysed with the registers of the cohorts from the ... sampling time before onset of symptoms of joint disease was 2.0 years (IQR 0.9–3.9 years) The antedating time for the samples was calculated to the onset of any symptoms of RA in all prepatients...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "The MHC2TA -168AG gene polymorphism is not associated with rheumatoid arthritis in Austrian patients" pps
... the MHC2TA gene might help to elucidate the role of this gene for RA The lack of correlation between the presence of the specific RA autoantibodies aCCP or rheumatoid factor with MHC2TA alleles ... rheumatoid arthritis Results of an analysis from a nationwide twin study J Rheumatol 1994, 21:1420-1426 Deighton CM, Walker DJ, Griffiths ID, Roberts DF: The contribution of HLA to rheumatoid ... future onset of rheumatoid arthritis and has a specificity of 100% for the disease Arthritis Res Ther 2006, 8:R19 Barton A, Ollier W: Genetic approaches to the investigation of rheumatoid arthritis...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Deficiency of functional mannose-binding lectin is not associated with infections in patients with systemic lupus erythematosu" pptx
... generation of autoantibodies in systemic lupus erythematosus Rheumatology (Oxford) 2005, 44:111-119 Hochberg MC: Updating the American College of Rheumatology revised criteria for the classification of ... and response to antibiotic treatment Lower urinary tract infections were excluded because of potential under-reporting of this infection Viral infections were included if clinical symptoms of ... or HYB 131-1 (a kind gift of S Thiel, University of Aarhus, Aarhus, Denmark), which revealed comparable results A cutoff value of less than 0.05 μg/ml MBL corresponds to low-level-producing MBL...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo y học: "Aortic dissection associated with cogans’s syndrome: deleterious loss of vascular structural integrity is associated with GM-CSF overstimulation in macrophages and smooth muscle cells" docx
... Main author, histologic studies, contribution to arrangement of the manuscript; ÖS: MD, assembly of clinical data, contribution to arrangement of the manuscript; CV: MD, contribution to clinical ... exceeding elastolysis and collagenolysis and thus a dramatic loss of structural integrity Interestingly, in areas of exceeding matrix deterioration the level of GM-CSF, a proinflammatory mediator and ... regulator of the vascular collagen and elastin metabolism [5,6], was massively increased In summary, our data suggest that the persistently increased secretion of the inflammatory mediator GMCSF...
Ngày tải lên: 10/08/2014, 09:22
báo cáo khoa học: "Overexpression of LCMR1 is significantly associated with clinical stage in human NSCLC" ppt
... regulation of the transcription of genes is vital to the execution of complex gene functions in response to growth, apoptosis, developmental and homeostatic signals, etc [15,16] MED1 has been found to ... transcriptional activators, which lead to activation of transcription at the target gene It has been reported that normal function of activators, such as VP16 and p53, interact with different Mediator subunits ... also found to be a member of mammalian Mediator subunits, called MED19 [10,11] The mediator complex is a large collection of DNA binding transcriptional activators through the action of an intermediary...
Ngày tải lên: 10/08/2014, 10:21