respective roles of the component and its environment
Báo cáo khoa học: Respective roles of the catalytic domains and C-terminal tail peptides in the oligomerization and secretory trafficking of human acetylcholinesterase and butyrylcholinesterase potx
Ngày tải lên :
07/03/2014, 03:20
... major function of the t peptides is that they allow the assembly of tetramers of AChET [7] and of BChET [8] and their association with the structural proteins ColQ and PRiMA [9,10] These heteromeric ... three residues of peptide b (GNI) as a group; W8 and E9 together and separately; G13, N18, M22 and D23 together and separately; and N29 and D30 together, replacing these residues by the corresponding ... higher proportion of tetramers (not shown) For the chimeras Ab and Ba, the rates of secretion were approximately 5% and 15% of the cellular content per hour, respectively, and therefore appeared...
- 15
- 446
- 0
Evolution of the Earth and its Atmosphere and its Atmosphere
Ngày tải lên :
04/04/2013, 10:51
... much warmer, thereby preventing freezing and accelerating surface “weathering” Except for Oxygen, almost all of the Earth’s atmosphere today Evolution of the Earth Process and Equation” its Atmosphere ... 200 years ago, the industrial age, with its demand for fossil fuels, was getting underway ♦ The impact of people on the atmosphere was about to become noticeable! The Earth and its Atmosphere ... led to the appearance☻ of primitive one-celled aquatic organisms which could survive in the oceans Life on Earth had begun, despite its inhospitable atmosphere! Evolution of the Earth and its Atmosphere...
- 18
- 517
- 0
A comparison on cohesive devices between the gift of the magi and its two vietnamese translation versions
Ngày tải lên :
14/12/2013, 00:40
... Review of the theories related to cohesion and translation - Analysis and synthesis of the collected data Design of the Study The thesis consists of three parts: Part I: Introduction states the ... for success of this translation and the failure of the other There have been some works that analysed and contrasted cohesion between English and Vietnamese so far The purpose of these works ... choosing the topic, the aim, its scope, the research question and method of the study Part II: Development consists of chapters: Chapter 1: Theoretical background states the theoretical background of...
- 61
- 1K
- 2
Tài liệu MECHANICAL PROPERTIES OF THE HEART AND ITS INTERACTION WITH THE VASCULAR SYSTEM ppt
Ngày tải lên :
22/02/2014, 09:20
... understanding and will be the focus and repeating theme throughout the text A sound understanding of cardiac physiology begins with basic understanding of cardiac anatomy and of the physiology of ... contraction and instantaneous atrial volume) The pressure of the point at the bottom right corner of the loop is the pressure in the ventricle at the end of the cardiac cycle and is called the end-diastolic ... contraction process of the cardiac muscles and the properties of the arterial system and is beyond the scope of this lecture As the contraction process of the cardiac muscle reaches its maximal effort,...
- 23
- 578
- 0
Báo cáo khoa học: Roles of the SH2 and SH3 domains in the regulation of neuronal Src kinase functions pptx
Ngày tải lên :
06/03/2014, 01:20
... R175K mutations therefore inhibit interactions with ligands of the SH3 and SH2 domains, respectively, both intra- and intermolecularly, and thereby disrupt the overall functions of Src kinase [3,18–21] ... upstream of the conserved PXXP motif of the SH3 ligand The D99N mutation prevents formation of this salt bridge and disrupts the SH3 binding specificity R175 (corresponding to R183 in n-Src) in the ... dysfunction SH3 and SH2 domain dysfunction Deletion of N-terminal, SH3 and SH2 domain of active n-Src Deletion of N-terminal, SH3 and SH2 domain of kinase-dead n-Src of PP3, the inactive form of PP2,...
- 11
- 597
- 0
Stress and Performance - A Review of the Literature and Its Applicability to the Military pdf
Ngày tải lên :
29/03/2014, 18:20
... (NSRD) of the RAND Corporation NSRD conducts research and analysis for the Office of the Secretary of Defense, the Joint Staff, the Unified Commands, the defense agencies, the Department of the ... which conducts research and analysis for the Office of the Secretary of Defense, the Joint Staff, the Unified Commands, the defense agencies, the Department of the Navy, the U.S Intelligence Community, ... and through the demands of their daily jobs These types of stressors can take a significant toll on the performance, functioning, and effectiveness of military personnel For example, Mareth and...
- 86
- 607
- 0
Báo cáo y học: "κ The roles of the classical and alternative nuclear factor-κB pathways: potential implications for autoimmunity and rheumatoid arthritis" ppsx
Ngày tải lên :
09/08/2014, 10:23
... producers of IL-17 We then discuss the biologic effects of Th17 and IL-17 in the context of RA, and the direct Page of 14 (page number not for citation purposes) Arthritis Research & Therapy Vol ... sclerosis and RA (see below), evidence for its roles in the other human diseases is more circumstantial and often rests on the detection of high expression levels of IL-17 at sites of inflammation ... subunit of NF-κB or the pathway(s) that leads to its activation in a particular disease To discover such targets and inhibitors, we need to advance our understanding of the roles of NF-κB and its...
- 14
- 317
- 0
Dismembering appearances the cultural meaning of the body and its parts in eighteenth century understanding
Ngày tải lên :
18/11/2015, 09:55
... air, food and drink, sleep and wake, exercise and rest, evacuations and obstructions, and the passions of the mind.102 Around the middle of the century the 96 P Slack, ‘Mirrors of Health and Treasures ... for the Year 1770’, from D Ritchie, Treatise on the Hair (London, 1770) Illustration showing the names of the lines of the hand, from E Pater, The Book of Knowledge Shewing the Wisdom of the ... the analysis will investigate the class based associations attached to the appearance and uses of the hands, and how the elites and the lower classes were characterised by the actions which their...
- 314
- 573
- 0
30 5 The End of the War and its Legacy
Ngày tải lên :
23/06/2016, 00:18
... administration is found corrupt and that the president lied about the war during the Watergate Scandal 12 Many Americans lose faith in their government The publication of the Pentagon Papers On ... invasion of South Vietnam and the capture of Saigon leads to the South’s surrender No U.S troops were there to prevent the North’s victory Vietnam veterans receive a cold homecoming At the time, ... administration is found corrupt and that the president lied about the war during the Watergate Scandal Henry Kissinger Nixon advisor who helped negotiate and end to the war ...
- 15
- 433
- 0
Báo cáo y học: "Bench-to-bedside review: Functional relationships between coagulation and the innate immune response and their respective roles in the pathogenesis of sepsis" ppsx
Ngày tải lên :
12/08/2014, 19:21
... exoskeleton of the crab immediately jeopardizes the integrity of the internal milieu of the organism Not only is there a real threat of loss of internal contents of the crab to the external environment, ... integument of the animal, and it seals off the injured area from the remainder of the crab’s open circulatory system The animal will often clot off and sacrifice an entire extremity (they have ... internal ligand that is tethered to the amino-terminus of its extracellular domain Thrombin cleaves the amino-terminus of the PAR, allowing the internal ligand to autoactivate the receptor There are...
- 16
- 347
- 0
United Nations Convention on the Law of the Sea and the polar marine environment
Ngày tải lên :
01/11/2013, 09:20
... that not impinge on the unresolved problem of the status of Antarctica (e.g., the regime of the high seas, the main principles on the protection of the marine environment, and the dispute settlement ... differences, both the Arctic and the Antarctic could be considered as ‘regions’ in the context of the contemporary law of the sea and the actual cooperation of states as to the demanding tasks of exploring, ... established and maintained; the list of experts in the field of the protection and preservation of the marine environment shall be drawn up and maintained by the United Nations Environment Programme, and...
- 23
- 658
- 0
Tài liệu An Account of the Foxglove and some of its Medical Uses pptx
Ngày tải lên :
17/02/2014, 23:20
... cases lost to An Account of the Foxglove and some of its by William Withering the common run of practice, and only snatched from destruction, by the efficacy of the Digitalis; and this in so remarkable ... afforded me, in perfecting some of the cases, and in communicating the events of others The ages of the patients are not always exact, nor would the labour of making them so have been repaid by any ... remarkable swelling of the upper lip, and painful tumours of the joints of the fingers, much relieved; but the medicine was left off, on account of its violent effects on the constitution Ib...
- 86
- 565
- 0
Tài liệu Báo cáo khoa học: Verprolin function in endocytosis and actin organization Roles of the Las17p (yeast WASP)-binding domain and a novel C-terminal actin-binding domain doc
Ngày tải lên :
18/02/2014, 16:20
... is further evidence that the functions of Vrp1p in endocytosis, cytokinesis, and growth at elevated temperature, on the one hand, and in cortical actin-patch polarization, on the other hand, are ... proteins, but we expect that the relative expression level of the tagged proteins is indicative of that of the equivalent untagged proteins To assess the function of these proteins in endocytosis ... expect that the relative expression level of the GFP-tagged proteins is indicative of that of the equivalent untagged proteins Lipid anchoring of C-Vrp1p bypasses the requirement for the LBD for...
- 23
- 679
- 0
Tài liệu Báo cáo khoa học: Roles of the human Rad51 L1 and L2 loops in DNA binding doc
Ngày tải lên :
19/02/2014, 06:20
... in these eukaryotic and archaeal proteins (Fig 1A) Like the case of bacterial RecA, the L1 and L2 loops of the eukaryotic Rad51 proteins face A Roles of the HsRad51 L1 and L2 loops inside of their ... Roles of the HsRad51 L1 and L2 loops D231W (L1 loop) Table Changes in the fluorescence of tryptophan probes inserted in the L1 and L2 loop upon binding of nucleotides and DNA The fluorescence of ... Results Strategy of mutational analysis In order to study the functions of the L1 and L2 loops of HsRad51, we examined the effect of replacing the aromatic residues in the L1 and L2 loops with...
- 12
- 662
- 0
Tài liệu An Account of the Foxglove and some of its Medical Uses With Practical Remarks on Dropsy and Other Diseases doc
Ngày tải lên :
19/02/2014, 11:20
... cases lost to An Account of the Foxglove and some of its by William Withering the common run of practice, and only snatched from destruction, by the efficacy of the Digitalis; and this in so remarkable ... afforded me, in perfecting some of the cases, and in communicating the events of others The ages of the patients are not always exact, nor would the labour of making them so have been repaid by any ... remarkable swelling of the upper lip, and painful tumours of the joints of the fingers, much relieved; but the medicine was left off, on account of its violent effects on the constitution Ib...
- 86
- 598
- 0
Báo cáo khoa học:The principle of flux minimization and its application to estimate stationary fluxes in metabolic networks docx
Ngày tải lên :
07/03/2014, 15:20
... Thus, given the values of the four target fluxes v9, v16, v21 and v26, the values of all other stationary fluxes are fully determined by the value of the glucose uptake flux Calculation of the stationary ... this report briefly outlines the mathematical basis of the method The second part presents two applications of the method to the metabolism of erythrocytes and of the microorganism, Metylobacterium ... the uptake component of the flux to zero, as follows: ðuptakeÞ vi ¼0 ð4Þ Thermodynamic evaluation of fluxes: irreversibility of reactions The direction of any flux vj is dictated by the change of...
- 18
- 799
- 0
Báo cáo khoa học: Delineation of the roles of FadD22, FadD26 and FadD29 in the biosynthesis of phthiocerol dimycocerosates and related compounds in Mycobacterium tuberculosis pptx
Ngày tải lên :
15/03/2014, 11:20
... Schematic representation of the roles of the FadD proteins encoded by the DIM + PGL locus in the biosynthesis of DIMs and related compounds in Mycobacterium tuberculosis The role of the activation enzymes ... promote the transfer of the p-HB moiety onto PKS15 ⁄ [16,18] To examine the involvement of FadD29 in the biosynthesis of DIMs and PGLs, we took advantage of the existence in the laboratory of an ... the activation of the various intermediates in DIM and PGL biosynthesis has not been analyzed This study was undertaken to dissect the roles of FadD22, FadD26 and FadD29 in the biosynthesis of...
- 11
- 550
- 0
The Economics of Small Business Finance: The Roles of Private Equity and Debt Markets in the Financial Growth Cycle potx
Ngày tải lên :
15/03/2014, 21:20
... businesses and academics in the nature and behavior of the financial At the core of this issue are questions about the type of financing need and receive at various stages of their growth, the nature of ... implications among these alternative of small business finance is a growing of small business finance For example, the impact of the U.S of the early 1990s and the effect of the consolidation of the banking ... credit, and other sources of funds These data allow for tests of research regarding the cost and availability of different types of external finance and how the cost and availability vary with the...
- 69
- 1.3K
- 1
Báo cáo khoa học: Dual mitochondrial localization and different roles of the reversible reaction of mammalian ferrochelatase ppt
Ngày tải lên :
16/03/2014, 00:20
... in the expression of ferrochelatase, which plays a role in the iron-removal reaction of exogenous heme and the change in position of the heme-moiety of hemoproteins The protoporphyrin ring of the ... membranes of mitochondria and the possible regulation of its reversible enzyme activity by phosphorylation Phosphorylation of the enzyme may relate to the activities and differential localization of ... phosphorylated in E coli, (Fig 4F, lower), the intensity of phosphoferrochelatase of S130A and S303A was decreased, and the band was not detected in the double mutant S130A and S303A, indicating that ferrochelatase...
- 12
- 548
- 0
STATE OF THE ART IN BIOSENSORS - ENVIRONMENTAL AND MEDICAL APPLICATIONS potx
Ngày tải lên :
16/03/2014, 12:20
... system, the use of discretized side chains, and the lack of precise modeling of backbone flexibility, affect the reliability of the method Therefore, instead of relying on the accuracy of the single ... recognition of different compounds and the immobilization of bio-se‐ lective materials; the second on the transduction methods of the signals of bio-recognition reactions and the third on the signal ... Organization of Results” The division of the chapters into sections is based on the major focus of these studies and is not limiting the topics handled – valuable results and new ideas of different...
- 360
- 5K
- 0