reproducibility of oct retinal thickness measurement in patients with dme

... setting of more routine decompensated heart failure, and the effect milrinone in ischemic subset of patients deserves further investigation Conclusion Initiation of milrinone therapy in patients ... studies examining natriuretic peptide levels and/or inflammatory markers during inotrope administration with inconsistent results [8-11] Adding complexity to this picture is data indicating that ... regarding the effect of milrinone on apoptosis markers, or whether high-sensitivity troponin may reveal sub-clinical cardiac injury due to inotrope initiation We sought to determine the effect of initiating...

Ngày tải lên: 18/06/2014, 15:20

... quality of life even before the fracture occur [29-32] The wrist patients have a modest decrease in health-focused quality of life within physical domain and scores in accordance with controls within ... or both of the total hip or lumbar spine L2–L4 was found in 33% of the wrist fracture patients, 59% of the hip fracture patients, and 16% of the controls The difference in frequency of osteoporosis ... P: Risk of new clinical fractures within years following a fracture Osteoporos Int 2006, 17:348-354 Fayers PM, Machin D: Quality of life: the assessment, analysis and interpretation of patient-reported...

Ngày tải lên: 18/06/2014, 19:20

... number of CD4+CD28– T cells in each of these disease categories is shown in Table The frequency of CD4+CD28– T cells was 4.82% in patients with limited joint manifestations, 7.05% in those with ... joint involvement The lowest frequency of CD4+CD28– T cells was in RA patients with limited joint manifestations Significantly higher numbers of CD28– lymphocytes were present in patients with ... thrombosis Clonal expansion of CD4+CD28– T cells has been found in the inflamed plaque of such patients [12] Table Frequency of CD4+CD28– T cells in control group and in patients with RA Subjects CD4+CD28–...

Ngày tải lên: 09/08/2014, 01:22

... targets of anti-TNF-α activity in RA, and may provide an insight into a new and interesting mechanism of action of anti-TNF-α mAbs in the control of inflammatory arthritis Competing interests ... N-formyl-1methionyl-l-leucyl-1-phenylalanine: analysis of single cell movement J Leukocyte Biol 1992, 52:630-636 Binder R, Kress A, Kan G, Herrmann K, Kirschfink M: Neutrophil priming by cytokines and vitamin D binding protein (Gc-globulin): ... initiation of treatment with leflunomide or methotrexate in patients with rheumatoid arthritis: findings in a prospective, randomized, double-blind clinical trial in fifteen patients Arthritis Rheum...

Ngày tải lên: 09/08/2014, 06:22

... both endpoints were comparable in patients with active MGMT or with MGMT silencing The only subgroup of patients showing a significant impact of MGMTpromoter methylation on survival were patients ... mg in only 22%) as well as in the maintenance phase (no adjuvant treatment in 79 % and a mean of cycles in 21% of patients) However, inspite of this difference, outcome between the two dosing ... entity in upcoming studies The low number of primary GBM exhibiting IDH1 mutations in our series indicates that our sample set consists indeed predominately of these tumors IDH1mutations in GBM...

Ngày tải lên: 09/08/2014, 09:21

... other laboratory findings listed in Table None of the patients with pSS had an increased level of CRP There was a tendency for increased numbers of IL-10-secreting PBMC in patients with pSS (p < ... al We examined serum levels of MIF in patients with pSS and the relation of these levels to clinical and laboratory findings In addition, we analysed associations of MIF concentrations with various ... elevated in our cohort, the increased MIF levels in patients with pSS cannot be explained by differences in the extent of acutephase response Hence, specific mechanisms of MIF induction in pSS remain...

Ngày tải lên: 09/08/2014, 10:20

... combined with parotid salivary output of patients with head-and-neck malignancies treated with RT We found a deterioration of most of the QOL items after completion of radiotherapy compared with ... RT with curative intent were included in the study Other inclusion criteria were no previous RT or surgery of the parotid glands, no history of suffering from malignancies or other diseases of ... http://www.ro-journal.com/content/2/1/3 Table 2: Mean scores of the scales and single items of questionnaire for patients with cancer of the head- and-neck treated with radiotherapy with or without surgery A significant outcome...

Ngày tải lên: 09/08/2014, 10:21

... compounds (4 patients) , Page of (page number not for citation purposes) cyclosporine A (5 patients: in combination with MTX, in combination with leflunomide, in combination with azathioprine, and with ... Vitamin D binding protein (Gc-globulin) Endocr Rev 1989, 10:294-307 18 Lind SE, Smith DB, Janmey PA, Stossel TP: Role of plasma gelsolin and the vitamin D-binding protein in clearing actin from ... model of plasma gelsolin (pGSN) function in clearing actin from synovial joints of rheumatoid arthritis patients with acute joint effusion (1) (pGSN) function in clearing actin from synovial joints...

Ngày tải lên: 09/08/2014, 13:22

... scleroderma and in 40% of patients with diffuse SSc [5] High-resolution computed tomography detects ILD changes in 90% to 100% of SSc patients [2,5] ILD is associated with increased mortality in patients ... data, CYC treatment in patients with SScrelated ILD does not appear to result in clinically significant improvement of pulmonary function Since none of the patients included in these studies were ... the drug in patients with SSc [28,29] The adverse events counted in our nine studies included two cases of hemorrhagic cystitis [17] and several cases of hematuria – one case in Valentini and...

Ngày tải lên: 09/08/2014, 13:22

... of the clinical centers specializing in the care of SSc patients participating in the network, but also of patients who are seen only once a year in a clinical center participating in the network ... College of Rheumatology criteria or the main symptoms of SSc, combined with another nonorgan-specific autoimmune disease or with the main symptoms of such a disease and, as a rule, with proof of characteristic ... College of Rheumatology, with the exception of higher rates of D-penicillamine use in SSc in North America (that is, 20% for skin involvement) Conclusion The present study is the first investigating...

Ngày tải lên: 09/08/2014, 13:22

... improvement of antiretroviral drug tolerability only in coinfected patients In conclusion, in HIV-1 infected patients presenting with an acute onset of abnormal LFTs, after the exclusion of the most ... performed for the onset of disseminated Kaposi’s sarcoma (KS) lesions with visceral involvement (CDC C3) HAART with indinavir, lamivudine and stavudine was started, shortly allowing an immune-virological ... he continued HAART, switching from indinavir to nevirapine for simplification, and from stavudine to tenofovir for the onset of peripheral neuropathy During this period plasma HIV RNA remained...

Ngày tải lên: 10/08/2014, 05:22

... who demonstrated an increase in serum levels of these cytokines in patients with intermittent claudication The authors suggested that a high level of cytokines is indicative of some complications ... alanine aminotransferase (ALT), aspartate aminotransferase (AST), urea and creatinine of patients and control subjects are shown in Table Patients and control subjects presented levels within ... higher levels of these two proteins in patients than in the control group Table Concentrations of plasma glucose, alanine aminotransferase, aspartate aminotransferase, urea, creatinine, total cholesterol,...

Ngày tải lên: 11/08/2014, 03:20

... reported in patients with bipolar I or II depression receiving quetiapine or in patients with bipolar I depression receiving olanzapine/ fluoxetine [21-23] They are also within the range of values ... olanzapine alone (versus 1.4-3.6 points for olanzapine alone in the studies included in this analysis) and 5.9-7.8 points when combined with fluoxetine [21] In the current analysis, olanzapine also ... were in line with those reported from the observed case analysis The efficacy of asenapine in treating depressive symptoms is supported by in vitro and in vivo preclinical findings Asenapine has...

Ngày tải lên: 11/08/2014, 15:22

... measures investigated included incidence of unsolicited treatment-emergent adverse events occurring in ≥5% of patients or with between-groups p

Ngày tải lên: 11/08/2014, 16:23

... utilization of coping strategies in patients with chronic pain when their pain is at a moderate level of intensity or greater The VPMI has two validated subscales: active coping and passive coping [24] ... explained 49% of variance in BASFI scores More specifically, each numerical increase (range of scores to 27, with higher numbers equaling more depression) in depression resulted in an increase of ... functional limitation in the final model, mirroring findings in other chronic arthritic conditions [19,24,29,31-34] Our findings are also consistent with a previous report linking helplessness to...

Ngày tải lên: 12/08/2014, 11:22

... honeycombing involving up to 25% of the lobe, 3honeycombing involving 25–49% of the lobe, 4- honeycombing involving 50–75% of the lobe, 5- honeycombing involving > 75% of the lobe for interstitial ... only in 16% of our cohort but in 50% of patients with diffuse skin involvement, while moderate-severe restrictive lung disease occurred in 12% of the whole cohort and in 41.7% of the patients with ... HRCT performed in 93 SSc patients ** BAL performed in 42 SSc patients giving their informed consent of the patients without (p = ns) IL-6 plasma levels were higher in patients with positive BAL...

Ngày tải lên: 12/08/2014, 18:22

... pointed out earlier, in order to demonstrate the clinical effectiveness of immunotherapy in severe sepsis and septic shock, a number of 120 patients is necessary to be included in each arm of ... Analyzing the data by means of definitions of sepsis and septic shock, and assuming the patients to be a uniform group, we cannot demonstrate the special subgroups of patients in whom the administration ... effect of immunoglobulins could be shown Using such an approach, a beneficial effect of IgG immunotherapy in a special subgroup of septic patients has already been shown in the study by Dominioni...

Ngày tải lên: 12/08/2014, 19:21

Ngày tải lên: 12/08/2014, 19:21

... Endothelial injury, as indicated by increased sTM, was apparent in 72% of patients, and virtually all patients had evidence of systemic inflammation (elevated IL-6; 98.5% of patients) Baseline D-dimer, ... generation observed in patients who survived Prolongation of PT reflects the depletion of hemostatic factors in patients with severe sepsis and may be an initial indicator of disseminated intravascular ... prothrombin fragment 1.2; PAI, plasminogen activator inhibitor; TAFI, thrombin-activatable fibinolysis inhibitor; TAT, thrombin–antithrombin complex Figure Time courses of biomarkers of inflammation...

Ngày tải lên: 12/08/2014, 20:20

... hypotension MAP 5a or epinephrine ≤0.1a or norepinephrine ≤0.1a Dopamine >15a or epinephrine >0.1a or norepinephrine >0.1a Hematologic: platelet ... having SOFA-defined and MOD-defined cardiovascular failure, SOFA-defined but not MOD-defined cardiovascular failure, MOD-defined but not SOFA-defined cardiovascular failure, and patients without ... end-point Conclusion In patients with brain injury, the SOFA scoring system has superior discriminative ability and stronger association with outcome compared with the MOD scoring system with respect...

Ngày tải lên: 13/08/2014, 02:24