reporting of systematic reviews and meta analysis of randomized controlled trials

... (1/1945 to 12/ 2006), BIOSIS (1/1969 to 12/2006), and the Cochrane Database of Systematic Reviews and Central Register of Controlled Trials and manually searched retrieved bibliographies to identify ... tuberculosis skin testing and LTBI treatment, the prevalence and outcome of MTB infections, and the effects of patient factors and treatment on mortality from MTB infection PATIENTS AND METHODS plant ... rate of MTB reactivation,12 some transplant centers neither test for nor treat LTBI because of the perceived lack of efficacy and potential toxicity of drug therapy in liver transplant candidates.13-18...

Ngày tải lên: 29/03/2014, 03:20

... this is the first systematic review and meta- analysis of the relationship between OHRQoL and tooth loss Data from our systematic review and meta- analyses of observational studies provide fairly ... Moreover, the severity of impairment might be associated with location and distribution of missing teeth, as suggested by the outcome of the meta- analysis of data of a Greek and a British population ... Summary of primary and additional outcomes of all included studies Additional file 2: Summary of data of all included studies and feasibility for meta- analysis 14 15 Author details Department of Oral...

Ngày tải lên: 20/06/2014, 15:20

... [14] Methods Search procedure and data extraction This review follows the Preferred Reporting Items for Systematic reviews and Meta- Analyses (PRISMA) statement for meta- analysis [15] The following ... USA) using the user-contributed commands for meta- analyses: ‘metan’ [19], ‘metainf’ [20], ‘metabias’ [21] and ‘metatrim’ [22] In order to estimate whether the IQ of those suffering from AN differs ... total sample size of 365 AN patients The sample size of the trials ranged between 10 and 46 The mean IQ of the 14 studies ranged from 96.1 to 116.8 A meta- analysis using a random effects model...

Ngày tải lên: 09/08/2014, 01:21

... weeks' duration, 46% of doses were 200 mg and 46% were of 400 mg daily In trials of 24 weeks or longer, 92% of doses were of 800 mg daily Longerlasting trials used higher doses of celecoxib In comparisons ... efficacy and safety of rofecoxib [27], and only five trials with 5,400 patients taking celecoxib [28] Two previous systematic reviews of coxibs used company clinical trial reports Deeks and co-workers ... of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 1996, 17:1-12 Smith LA, Oldman AD, McQuay HJ, Moore RA: Teasing apart quality and validity in systematic reviews: ...

Ngày tải lên: 09/08/2014, 06:22

Ngày tải lên: 09/08/2014, 07:20

... MMF in lupus nephritis from randomised trials and observational studies Materials and methods QUOROM (quality of reporting of meta- analyses) and MOOSE (meta- analysis of observational studies in ... Rennie D, Stroup DF: Improving the quality of reports of meta- analyses of randomised controlled trials: the QUOROM statement Quality of Reporting of Meta- analyses Lancet 1999, 354:1896-1900 20 ... numbers of patients and events increase the risk of chance findings [64] The ideal is meta- analysis of high-quality, large, randomised trials [63], but without them we have to make the best of the...

Ngày tải lên: 09/08/2014, 08:23

... shortage of randomized controlled trials on this topic is a limitation, and larger randomized controlled trials are needed to better understand the role of CYC in the care of these patients In our meta- analysis, ... age and height The methodological features of all randomized clinical trials most relevant to the prevention of bias (including the Jadad criteria of randomization, blinding and completeness of ... pooled analysis of the treatment arms of the randomized clinical trials and of the observational studies suggested that both the FVC and DLCO predicted values improved after 12 months of therapy,...

Ngày tải lên: 09/08/2014, 13:22

... meta- analysis and systematic review of randomized controlled trials (RCTs) Methods: Eight RCTs published from 1999 to 2010 were identified and synthesized to compare the efficacy and safety of ... surgery for severe emphysema: meta- analysis and systematic review of randomized controlled trials Wei Huang, 1Wen R Wang, 1Bo Deng, 1You Q Tan, 1Guang Y Jiang, Hai Jing Zhou and 1Yong He 1 Thoracic ... efficacy and long-term sequel of LVRS And we conduct the systematic review of two approaches (MS vs VATS) and the materials (bovine pericardium for buttressing, autologous fibrin sealant and BioGlue)...

Ngày tải lên: 10/08/2014, 09:22

... mortality: systematic review and meta- analysis of randomized trials Mayo Clinic Proc 2008, 83(4):418-430 20 Pittas AG, Siegel RD, Lau J: Insulin therapy for critically ill hospitalized patients: a meta- analysis ... because of different approaches to collecting and reporting information, for example, the method of measuring time spent in ICU Conclusion The results of this systematic review of the literature and ... Haga et al.: The effect of tight glycaemic control, during and after cardiac surgery, on patient mortality and morbidity: A systematic review and meta- analysis Journal of Cardiothoracic Surgery...

Ngày tải lên: 10/08/2014, 09:23

... 11 of 13 shoes [8,23] Unfortunately, meta- analysis of kinematic variables was restricted by inconsistencies in biomechanical models and under -reporting of standard deviations/ error Meta- analysis ... children’s shoes on gait: a systematic review and meta- analysis Journal of Foot and Ankle Research 2011 4:3 Submit your next manuscript to BioMed Central and take full advantage of: • Convenient online ... relative to ipsilateral line of progression and angle of gait relative to the direction of gait The variable length comprised the average of stride and step length Wilkinson and coinvestigators [20]...

Ngày tải lên: 10/08/2014, 21:24

... co-segregation (higher prevalence of the endophenotype in ill relatives of ill probands than in well relatives of ill probands); and (v) heritability (the extent of variation of the endophenotype that ... al.: A systematic review and meta- analysis of neurological soft signs in relatives of people with schizophrenia BMC Psychiatry 2011 11:139 Submit your next manuscript to BioMed Central and take ... using Comprehensive MetaAnalysis version 2, a dedicated meta- analysis programme (BioStat, Inc, Englewood, NJ) The analysis was based on all included studies and consisted of three comparisons:...

Ngày tải lên: 11/08/2014, 15:22

... http://www.harmreductionjournal.com/content/6/1/25 Figure Random2effects meta- analysis of all NRT trials combined versus all inert controls at weeks Random effects meta- analysis of all NRT trials combined versus all inert ... patients are at increased risk of complications or repeat Figure effects meta- analysis of varenicline versus placebo at weeks post-TQD Random6 Random effects meta- analysis of varenicline versus placebo ... Bucher HC, Guyatt GH, Griffith LE, Walter SD: The results of direct and indirect treatment comparisons in meta- analysis of randomized controlled trials J Clin Epidemiol 1997, 50:683-691 Mills EJ, Wu...

Ngày tải lên: 11/08/2014, 18:20

... Page of 14 Table 1: Risk of bias (internal and external validity) of the randomised controlled trials' analysis Author, year Adequate randomisation Adequate allocation concealment Blinding of assessor ... antidepressants - a meta- analysis JAMA 2009, 301:198-209 Häuser W, Bernardy K, Üceyler N, Sommer C: Treatment of fibromyalgia syndrome with gabapentin and pregabalin - a meta- analysis of randomized controlled ... effects of AE Materials and methods The present review was performed according to the Preferred Reporting Items for Systematic Reviews and MetaAnalyses statement [14] and the recommendations of the...

Ngày tải lên: 12/08/2014, 12:20

... Prevention and Health Promotion, Office on Smoking and Health 2006 Department of Health Department of Health and Social Services Northern Ireland, The Scottish Office Department of Health and Welsh Office: ... methods, definition of LRI outcome, characteristics of reference group, ascertainment of passive smoke exposure, passive smoke source, and timing of exposure, location of study, and age of study population, ... of a total of eight points and case-control and cohort studies out of a total of nine points A score of seven or more was chosen a priori to indicate high methodological quality Statistical analysis...

Ngày tải lên: 12/08/2014, 13:22

... currently the 4th-leading cause of mortality and the 12th-leading cause of disability, by the year 2020 it will be the 3rd-leading cause of death and the 5thleading cause of disability worldwide [3,4] ... to analysis of the relationship between age and gender-related differences in the annual decline in FEV1% pred Unweighted smoking status Unweighted analysis of the relationship between age and ... Figure analysis of the relationship between age and gender-related differences in the annual decline in FEV1% pred for current smokers Weighted Weighted analysis of the relationship between age and...

Ngày tải lên: 12/08/2014, 16:20

... critical analysis of the safety of NPPV and CPAP in the treatment of ACPE A very recent meta- analysis unfortunately addressed only some of the questions to which clinicians need answers Masip and ... pressure support ventilation Materials and methods Study design A systematic review and meta- analysis of RCTs focusing on the effect of CPAP and NPPV in the treatment of ACPE was undertaken The methodological ... mortality and risk of newly developed AMI after delivery of study interventions To improve the internal validity of this meta- analysis, we decided to consider separately trials of NPPV and CPAP,...

Ngày tải lên: 12/08/2014, 23:23

... defined in each study), and the remaining 3% had indeterminate biochemical findings Methodological quality There were no randomized or non -randomized controlled trials of effusion drainage Fifteen ... difficult), and risk Goligher et al Critical Care 2011, 15:R46 http://ccforum.com/content/15/1/R46 Page 11 of 14 Figure Forest plot of meta- analysis of studies reporting the rate of hemothorax ... TA: Meta- Analyst: software for meta- analysis of binary, continuous and diagnostic data BMC Med Res Methodol 2009, 9:80 21 The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised...

Ngày tải lên: 14/08/2014, 07:21

... Summary of the completed checklist of quality measures for reporting of systematic reviews and meta- analyses Additional File 2: Summary of search strategy Detailed summary of search terms and strategy ... search of MEDLINE (1985 to July 2010), PubMed, EMBASE (1985 to July 2010), the Cochrane Central Registry of Controlled Trials, Web of Science, and Scopus to identify randomised trials and cohort ... other did not describe Page of 10 Table Summary of quality indicators and validity assessment of randomised trials fulfilling inclusion criteria Randomised control trials Bouman [10] Sugahara...

Ngày tải lên: 14/08/2014, 07:21

... log-transformed upper and lower limits of 95% CI by 3.92 These data of each study were entered into the Review Manager and Comprehensive Meta- Analysis to perform meta- analysis and meta- regression analysis ... inspection of funnel plots and therefore pooled estimates may be overestimated One of this study’s strengths is that it is the first systematic review and meta- analysis on associations between frailty and ... ORs and difference in gender proportion of each study was considered to be a possible moderator causing the heterogeneity based on the findings of the subgroup analysis and meta- regression analysis...

Ngày tải lên: 25/08/2016, 21:28

... Equivalence of single and dual task gait speed in the prediction of falls M This systematic review and meta- analysis of 31 studies revealed that slower gait speeds under both single and dual task ... when standing and walking, which are required in many real-life situations 4.3 Strengths and limitations of the analysis This is the first meta- analysis focusing on the predictive ability of walking ... CONTRIBUTORS JM and SL contributed to the conception and design of the review JM and DS contributed to the literature searching, data extraction and analysis JM and SL drafted the article and DS revised...

Ngày tải lên: 25/08/2016, 23:09