replication repair and stress response

... Homeostasis and Stress Response Kawai, N., Maeda Y., Kudomi N., Miyake K., Okada M., Yamamoto Y., Nishiyama Y & Tamiya T 2011 Correlation of biological aggressiveness assessed by 11Cmethionine PET and ... Molecular Imaging and Contrast Agent Database (MICAD): Evolution and Progress [Internet] Mol Imaging Biol Oct 12 Comar, D., Cartron J.C., Maziere M & Marazano, C 1976 Labelling and metabolism of ... or 11C-acetate, and 18F- or 11Ccholine J Nucl Med 52: 81-9 Janicki, S.M., Tsukamoto T., Salghetti S.E., Tansey W.P., Sachidanandam R., Prasanth K.V., Ried T., Shav-Tal Y., Bertrand E., Singer...

Ngày tải lên: 22/06/2014, 02:20

... understand common molecular responses to a given stressor The chapters in this book address stress response in yeast, plants and humans The topics discussed include acetic acid-induced stress response ... out by oligosaccharides, and particularly, by oligoglucans 2 Cell Metabolism – Cell Homeostasis and Stress Response Oxidative stress and reactive oxygen species Oxidative stress is defined as the ... Oxidative Stress Abel Ceron-Garcia, Irasema Vargas-Arispuro, Emmanuel Aispuro-Hernandez and Miguel Angel Martinez-Tellez Chapter Regulation of Gene Expression in Response to Abiotic Stress in...

Ngày tải lên: 22/06/2014, 03:20

... peroxidases and catalases 16 Cell Metabolism – Cell Homeostasis and Stress Response The analysis of differential gene expression and analysis of global patterns of gene expression using macro and microarray ... Homeostasis and Stress Response both by plant roots (ethanol and acetaldehyde) and the metabolism of anaerobic microorganisms (methane, ethane, unsaturated acids, aldehydes, ketones), and ethylene ... pattern, whatever the nature of the stressor 14 Cell Metabolism – Cell Homeostasis and Stress Response Examples of non-specific indications of the state of stress are: increased respiration,...

Ngày tải lên: 22/06/2014, 03:20

... anaerobic stress Annals of Botany, Vol 79, pp 3-20, ISSN 0305-7364 Vinit-Dunand, F.; Epron, D.; Alaoui-Sosse, B & Badot, P.M (2002) Effects of copper on growth and on photosynthesis of mature and expanding ... Vol.23, pp.893-902 38 Cell Metabolism – Cell Homeostasis and Stress Response Zhu, J-K (2001a) Cell signaling under salt, water and cold stresses Current Opinion in Plant Biology, Vol.4, pp 401-406, ... Homeostasis and Stress Response This reaction can also be catalyzed by univalent cuprous ion, which is oxidized to divalent ion Both the oxidized iron and cuprum can be re-reduced by O2•−, and the...

Ngày tải lên: 22/06/2014, 03:20

... ≈600 are repressed and ≈ 300 are induced The last set incorporates approximately 50 genes previously described as part of general stress response and which bear the stress response element (STRE) ... cellular processes and their modes of regulation Despite the differences in signalling pathways between yeast and higher eukaryotes current knowledge on cellular stress responses and programmed cell ... Bcl-w, Bcl-xL and Mcl-1), Bcl-2 effector proteins, (Bak and Bax), direct activator BH3-only proteins (Bid, Bim and Puma) and sensitizer/derepressor proteins (Bad, Bik, Bmf, Hrk and Noxa) Complex...

Ngày tải lên: 22/06/2014, 03:20

... accumulation of compatible solutes observed during the stress response Compatible solutes protect membranes and proteins against stress However, when stress is over, compatible solutes inhibit growth, ... Acta, Vol 1783, 12861302 98 Cell Metabolism Cell Homeostasis and Stress Response Pereira, C., Chaves, S., Alves, S., Salin, B., Camougrand, N., Manon, S., Sousa, M.J & CụrteReal, M (2010) Mitochondrial ... fungus Candida albicans Proc Natl Acad Sci USA, Vol 103, pp 726731 Phillips, A.J., Sudbery, I & Ramsdale, M (2003) Apoptosis induced by environmental stresses and amphotericin B in Candida albicans...

Ngày tải lên: 22/06/2014, 03:20

... Metabolism – Cell Homeostasis and Stress Response Kühlbrandt W Biology, structure and mechanism of p-type ATPases Nature 2004; 5:282295 Kustermans G, Piette J & Legrand-Poels S Actin-targeting ... Cell Metabolism – Cell Homeostasis and Stress Response Uranium in the environment, routes of entrance to the body and impact on health Uranium is a natural and commonly occurring radioactive ... (morphology and size) and route of intake 2.1 Chemical form Uranium is a heavy metal that forms compounds and complexes of different varieties and solubilities The chemical action of all isotopes and...

Ngày tải lên: 22/06/2014, 03:20

... destructive effects and there is no interaction between current chemo- and radiotherapy protocols and PDT The most common 152 Cell Metabolism Cell Homeostasis and Stress Response disadvantages ... fetal serum (Gibco, Grand Island, NY, USA), with 100 IU/mL penicillin, 100g/mL streptomycin and 2mmol/L glutamine (Gibco, Grand Island) in an humidified incubator with 5% CO2 and 95% air at 37oC ... species and conclude that endothelial cell photosensitivity may play a role in the vascular damage observed following PDT The inflammatory and immune response: The PDT oxidative stress and associated...

Ngày tải lên: 22/06/2014, 03:20

... Peng, Wang and Shan, 2009 sFRP(s) colon cancer, mesothelioma, bladder cancer Tan and Kelsey, 2009; Paul and Dey, 2008; Gehrke, Gandhirajan and Kreuzer, 2009 GSK-3β colorectal cancer Ge and Wang, ... 2009; Yanaga and Sasaguri, 2007) 184 Cell Metabolism – Cell Homeostasis and Stress Response Moreover, the betweenness centrality and bridging centrality (nodes between modules and connecting ... SMAD3 178 Cell Metabolism – Cell Homeostasis and Stress Response LRSAM1 (leucine rich repeat and sterile alpha motif containing1), also called RIFLE and TAL (TSG101-associated ligase), is an E3...

Ngày tải lên: 22/06/2014, 03:20

... Paul S and Dey, A., 2008, “Wnt Signaling and Cancer Development: Therapeutic Implication”, Neoplasma, Vol 55, pp 165-176 188 Cell Metabolism – Cell Homeostasis and Stress Response Peifer,M and ... and Tandem Mass Spectrometry”, Molecular and Cellular Proteomics, Vol 7, pp 1162-1173 Saneyoshi, T., Kume, S., Amasaki, Y., and Mikoshiba, K., 2002, “The Wnt/calcium pathway activates NF-AT and ... synthesized 196 Cell Metabolism – Cell Homeostasis and Stress Response predominantly by RNA polymerases II and III (Sharma et al., 2010; Sacco-Bubulya and Spector, 2002) or specifically in nucleoli...

Ngày tải lên: 22/06/2014, 03:20

... (Copeland, K.C., et al, 1993) and an increased appetite, promoting the mismatch between caloric intake and caloric requirements and thus exacerbating the syndrome (Unger, R.H., 2002) So far, the candidate ... phospholipids and ergesterol ester in DKO and wild type cells……………………………………………………127 4.3.4 DAG level under high salt stress …………………………………………128 4.4 Summary …………………………………………………………………………128 Role of DAG and ... profiles under TAG absence upon stationary phase and salt stress …………………………………………………………….203 Figure 7.2 The crosstalk of stress activated MAP kinase pathway and cAMP dependent kinase pathway in S pombe………………………………………………...

Ngày tải lên: 16/09/2015, 15:55

... A549, BHK, TC7, SW2, HL60 and HUVEC with respect to their response to hypoxia and reoxygenation The alkaline sedimentation profiles of HeLa and CCRF cells after hypoxia and reoxygenation already ... 4-(2-aminoethyl)bezenesulfonylfluoride/HCl (1 mM) and NaF (10 mM) and centrifuged for and 600 g at °C Nuclei were resuspended in extraction buffer three more times to fully lyse the nuclear envelope and complete extraction ... combined and yielded nucleosolic proteins The remaining pellet contains all DNA and structure bound proteins and is further referred to as chromatin-fraction Electrophoresis of proteins and Western...

Ngày tải lên: 21/02/2014, 00:20

... physiological stress responses and acquired thermotolerance J Appl Physiol 92, 2177–2186 Samali A, Holmberg CI, Sistonen L & Orrenius S (1999) Thermotolerance and cell death are distinct cellular responses ... 25 lm and n ¼ at ALI after weeks] Epidermal thicknesses measured in ALI cultures under sham and GSM-900 exposure were, respectively: 41.5 ± 8.7 and 37.9 ± 6.8 lm after weeks, 56.6 ± 9.9 and 45.0 ... base line This type of adaptation has been described as a normal response to thermal and chemical stress (i.e thermotolerance and chemotolerance), but has never been considered to be damaging...

Ngày tải lên: 07/03/2014, 11:20

... Oxidative stress responses of the yeast Saccharomyces cerevisiae Yeast 14, 1511–1527 Grant CM (2001) Role of the glutathione ⁄ glutaredoxin and thioredoxin systems in yeast growth and response to stress ... levels Data from [7] and [13] In H2O2- induced expression in tsa1 mutant cells (compare lanes and 8) Fig Expression of genes in wild-type and tsa1D cells exposed to several stressful conditions ... glutathione and NADPH [7] Msn2 and Msn4 activate genes whose promoters contain the stress responsive element (STRE: CCCCT) after several environmental challenges, including oxidative stress Despite...

Ngày tải lên: 16/03/2014, 14:20

... DNA repair, similar issues as in replication and transcription come to mind How does the repair machinery gain access to chromatin? How is chromatin restored after repair? As for replication and ... Sir2) and stabilizing the nucleosomes at the break point and in restricting access of replication and transcription factors to the site until repair is completed Chromatin remodeling during repair ... helicase and is required for the repair of damaged DNA Thus, in agreement with a role of Tip60 in DNA repair, the expression of a mutant version of Tip60 causes defects in DNA repair and reduces...

Ngày tải lên: 16/03/2014, 16:20

... reduced forms and a methionine residue The cluster is likely to be involved in redox reactions and might constitute the molecular basis of oxidative stress response by annexins Materials and methods ... forms the molecular basis of oxidative stress response by these proteins Similarly, an annexin from M sativa was reported to act as stress- response protein [7] and several mammalian annexins are ... annexins in the oxidative stress response Oxy5, an annexin-like protein from Arabidopsis, was shown to rescue E coli DoxyR mutants and protect mammalian cells from oxidative stress [8,9] In particular,...

Ngày tải lên: 17/03/2014, 03:20

... in the PVN and SON [12,17,21] The structure and function of the relaxin family peptide receptors, including RXFP3 and RXFP4, were recently reviewed by Kong et al [22] Cont Stress B Stress CRF ... pars compacta and pars dissipata, and relaxin-3positive neurons are found in both regions (Fig 1A) With reference to the distribution of relaxin-3-positive nerve fibers and RXFP3 and RXFP1 expression, ... in this minireview series [36,37] Stress response The NI is a region showing abundant expression of CRFR1, and strong c-Fos induction was observed in the NI in response to an intracerebroventricular...

Ngày tải lên: 29/03/2014, 21:20

... to abiotic and biotic stress responses In plants, Ca2+ and ROS constitute important and common signaling molecules in the early response to abiotic and biotic stress Levels of Ca2+ and ROS rapidly ... of stress Phytohormones also play central roles in abiotic and biotic stress signaling SA, JA and ET have central roles in biotic stress signaling ABA is involved in the response to abiotic stress ... pathways for biotic and abiotic stress responses are DEAR1, BOS1 and SlERF5 DEAR1 is a transcriptional repressor of DREB protein that mediates plant defense and freezing stress responses in Arabidopsis;...

Ngày tải lên: 28/06/2014, 08:20

... solutions were determined The SOD and catalase were assayed using the modified method of Elstner and Heupel (1976) and Ganschow and Schike (1969), respectively, and these results were then normalized ... Ball and Pidsley (1995) Kawamitsu et al (1995) also reported a depression of photosynthesis (Pmax ) in the Okinawa mangrove species Kandelia candel, B gymnorrhiza and Rhizophora stylosa in response ... differences in salt concentration between xylem sap and medium as those reported by Scholander and co-workers (Scholander et al., 1962; Scholander, 1968) As seen in Fig 3, salt concentrations...

Ngày tải lên: 06/07/2014, 02:20