... demands arising from taking care for a patient as well" Burden on relatives of patients with schizophrenia has been found associated with an important reduction in their QOL, causing damage in caregiver's ... regarding what instrument is the most appropriate to employ in the case of caregivers of patients with schizophrenia in order to measure their QOL In addition, future research is needed going beyond ... and Paulina Toledo Carrasco for their assistance in primary data cleaning and analyzing, and translation of the manuscript References b) The criteria adopted for including associations in the...
Ngày tải lên: 18/06/2014, 19:20
... Importantly, the inclusion of patients who were continuously treated with the index drug during the year following initiation was aimed at avoiding the potential pitfalls associated with an intent-to-treat ... hospitalization during the treatment of adherent patients with schizophrenia in usual care settings Patients who were newly initiated on olanzapine or risperidone and continued treatment with the index antipsychotic ... hospitalization for patients with schizophrenia who were treated in usual care settings Current findings complement prior findings from clinical trial research, thus providing clinicians and mental...
Ngày tải lên: 08/08/2014, 20:23
Báo cáo y học: "Binge eating symptomatology in overweight and obese patients with schizophrenia: a case control study" ppt
... (12,2%) in psychotic patients treated by clozapine or olanzapine, especially in the high body mass index (BMI) subgroup [3] The purpose of this study is to assess binge eating symptomatology in a ... case-control study Subjects' BMI was calculated as weight in kilograms divided by the square of height in meters Binge eating status was assessed through a clinical interview, using DSM-IV criteria (SCID-IV) ... other compensatory behaviours were also investigated With regard to this assessment, patients and controls were classified as having (1)no bingeing, (2) binge episodes less than days per week (BS),...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo khoa học: "Relationship of cognitive function in patients with schizophrenia in remission to disability: a cross-sectional study in an Indian sample" pps
... [6] In patients with schizophrenia, delusions and hallucinations could arise as a result of deficits in cognitive functions involving perceptual and attributional biases [7,8] People with schizophrenia ... not correlate with occupational functioning [32] Addington et al found no association between cognitive measures and social functioning in 30 patients with schizophrenia [35] The reason for these ... in schizophrenia Indian J Psychol Med 2001, 24:19-26 Indian Psychiatric Society: IDEAS (Indian Disability Evaluation and Assessment Scale) – A Scale for Measuring and Quantifying Disability in...
Ngày tải lên: 08/08/2014, 23:20
Báo cáo y học: "Costs and effects of paliperidone extended release compared with alternative oral antipsychotic agents in patients with schizophrenia in Greece: A cost effectiveness study" pdf
... in the therapeutic area of schizophrenia is vast and growing rapidly, and was helpful in developing a solid and definitive model Information that was not available in the literature was obtained ... the dominant strategy in all tests except in the case of a 10% increase in the resource utilisation of patients in stable days and 10% decrease in resource utilisation of relapses In both cases ... 30% decrease in PANSS from baseline to study endpoint or CGI-I ≤ 23.3 40.0 [35] 10 ≥ 30% decrease in PANSS from baseline to study endpoint 27.4 50.1 [21] [22] [23] 750 ≥ 30% decrease in BPRS at...
Ngày tải lên: 08/08/2014, 23:21
Báo cáo y học: "Costs and effects of paliperidone extended release compared with alternative oral antipsychotic agents in patients with schizophrenia in Greece: a cost effectiveness study" ppsx
... M, Athanasakis K, Papanicolaou S, Kyriopoulos I: Costs and effects of paliperidone extended release compared with alternative oral antipsychotic agents in patients with schizophrenia in Greece: ... come to our attention that there was an error with the values listed for Ziprasidone and Aripiprazole in Table Ten Table Ten should therefore appear as shown in this correction (Table 1) References ... cost per patient by pharmaceutical treatment Paliperidone ER Base case: Cost (€) Effectiveness Olanzapine Risperidone Quetiapine Ziprasidone Aripiprazole 7.030 272.5 7.034 272.2 7.082 265.5 8.321...
Ngày tải lên: 08/08/2014, 23:21
Báo cáo y học: "Fluvoxamine for aripiprazole-associated akathisia in patients with schizophrenia: a potential role of sigma-1 receptors" ppt
... (olanzapine, quetiapine, or risperidone)[14] Here, we report two cases in which fluvoxamine was effective in treating aripiprazole-induced akathisia in patients with schizophrenia Written informed consents ... akathisia of patients with schizophrenia Furthermore, we have experienced that fluvoxamine is Page of also effective in the treatment of other antipsychoticinduced akathisia in patients with schizophrenia ... two cases suggest that fluvoxamine may serve as an alternative option in the treatment of antipsychoticinduced akathisia in patients with schizophrenia More detailed randomised, double-blind studies...
Ngày tải lên: 08/08/2014, 23:21
Báo cáo y học: "Fluvoxamine for blonanserin-associated akathisia in patients with schizophrenia: report of five cases." pps
... where fluvoxamine was effective in treating blonanserin-associated akathisia in patients with schizophrenia Case reports Table shows the characteristics of five patients with blonanserin-associated ... medical center with a right calcaneal fracture His right leg joint was fixed in a plastic cast, and he was admitted Treatment with blonanserin (8 mg) and flunitrazepam (2 mg, at night) was initiated ... demonstrating that fluvoxamine is rapidly effective in the treatment of blonanserin-induced akathisia in patients with schizophrenia Very recently, we reported that fluvoxamine is also effective in...
Ngày tải lên: 08/08/2014, 23:21
Báo cáo y học: "Predicting hospital admission and discharge with symptom or function scores in patients with schizophrenia: pooled analysis of a clinical trial extension" doc
... analysis set was defined as open-label patients who had at least one post-baseline PSP and PANSS measurement Of the 1,077 patients who continued to the open-label phase, 1,028 were used in this analysis ... open-label patients who had at least one post-baseline PSP and PANSS measurement Definitions PANSS The development of the PANSS was published in 1987 [1] Schizophrenia symptoms such as delusions, ... abuse within months before screening (not including nicotine and caffeine addiction) Additional inclusion and exclusion criteria are presented in the previous reports from the randomized blinded...
Ngày tải lên: 08/08/2014, 23:21
Báo cáo y học: "A randomised, double-blind, placebo-controlled trial of tropisetron in patients with schizophrenia" pps
... altered in the intact brain of patients with schizophrenia A positron emission tomography (PET) study using the selective α7 nAChR ligand [11C]CHIBA-1001 [52,53] in the intact brains of patients with ... gating P50 deficits in patients with schizophrenia, and that tropisetron had a significant impact on the sustained visual attention measured with the RVP subtest of CANTAB in non-smoking patients ... nAChRs as well as a full agonist at α7 nAChR agonists, was not effective in the auditory P50 deficits in patients with schizophrenia [46] The precise reasons underlying the lack of varenicline on...
Ngày tải lên: 08/08/2014, 23:21
Báo cáo y học: "A 64-week, multicenter, open-label study of aripiprazole effectiveness in the management of patients with schizophrenia or schizoaffective disorder in a general psychiatric outpatient setting" pptx
... medication during the 12-week switching period is shown in Figure Both patient and caregiver POM ratings for aripiprazole increased during the 12-week switching phase At the end of the switching phase ... from baseline to week 64 -0.7 ± 1.1*** Change from baseline to endpoint (LOCF) -0.3 ± 1.1*** BPRS: Baseline 49.8 ± 17.5 Change from baseline to week 12 -6.5 ± 10.5*** Change from baseline to ... 11.6*** Change from baseline to endpoint (LOCF) -5.8 ± 15.9*** *P < 0.05 vs baseline; **P < 0.01 vs baseline; ***P < 0.001 vs baseline BPRS = Brief Psychiatric Rating Scale; CGI-S = Clinical Global...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: "Validation of a specific measure to assess healthrelated quality of life in patients with schizophrenia and bipolar disorder: the ‘Tolerability and quality of life’ (TOOL) questionnaire" doc
... the Structured Clinical Interview for DSM-IV, being clinically stable (defined as having had no changes in severity or new treatments initiated in the last month), and taking a single oral antipsychotic ... two groups: patients with no to mild involvement versus patients with moderate to severe involvement It was hypothesised that patients with lesser involvement would obtain lower scores in the TOOL ... and improve alliances between patients and clinicians [8] The importance of involving patients in their own healthcare, and of patient-reported assessments, is increasingly recognised [9] Many efforts...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: "Onset of efficacy with acute long-acting injectable paliperidone palmitate treatment in markedly to severely ill patients with schizophrenia: post hoc analysis of a randomized, double-blind clinical trial" doc
... Consistent with the known pharmacology of paliperidone, mean prolactin levels increased from baseline to end point in the markedly to severely ill population, with a greater increase observed in women ... differences in continuous variables were evaluated using an analysis of covariance (ANCOVA) model, with treatment and country as factors and baseline score as a covariate Changes from baseline are ... were observed in the mean change from baseline to end point score for these movement disorder rating scales The LS mean (SE) weight change (kg) from baseline to end point was 0.4 (0.7) in the placebo...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: "Comparison of prevalence of metabolic syndrome in hospital and community-based Japanese patients with schizophrenia" potx
... among patients receiving different types of care In this study, we reported the prevalence of MetS in inpatients and outpatients diagnosed with schizophrenia Compared to inpatients, outpatients ... male inpatients using the IDF definition, while male inpatients showed a higher prevalence of MetS than female inpatients using the JASSO definition The prevalence rates of MetS reported in previous ... were measured, and body mass index (BMI) was calculated Waist circumference to the nearest 0.1 cm was measured at the umbilical level with the subject in a standing position by a technician in the...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: " Previous hospital admissions and disease severity predict the use of antipsychotic combination treatment in patients with schizophrenia" pps
... were investigators in the study, with a background either as medical doctor or clinical psychologist The raters were trained in clinical interviews and assessments including video and case report ... antipsychotic combination treatment increased with number of hospital admissions, severity of the disease as measured with PANSS, and level of dysfunction, as measured with GAF The current finding that ... decline in global- or daily functioning, measured with GAF [9,21] This could be due to a type II error, at least in one of the studies, since this only included inpatients [9] The current finding...
Ngày tải lên: 11/08/2014, 15:22
Báo cáo y học: " Assessment of effectiveness measures in patients with schizophrenia initiated on risperidone longacting therapy: the SOURCE study results" ppt
... ongoing multinational, observational registry study, has been evaluating outcomes in patients with schizophrenia After 24 months of follow-up in eSTAR in Spain, RLAT use was associated with increased ... Improvement from baseline in Global Assessment of Functioning (GAF) score Scores are presented as least-squares (LS) means except for the baseline value, which is unadjusted Patients included in this analysis ... patients who had a non-missing baseline and at least one postbaseline assessment for a given effectiveness measurement and used mixed-model methodology with baseline value as a covariate, a fixed...
Ngày tải lên: 11/08/2014, 16:20
Báo cáo y học: " Resource utilization in patients with schizophrenia who initiated risperidone longacting therapy: results from the Schizophrenia Outcomes Utilization Relapse and Clinical Evaluation (SOURCE)" pdf
... between the prebaseline and postbaseline periods for hospitalization and ER visits A subgroup analysis was performed on patients with >2 RLAT injections who had valid dates in the prebaseline period ... RLAT initiation from 250 patients with schizophrenia The mean number of days spent in the hospital per patient increased from 31 in year -3 to 44 in year -2, to 90 in year -1, and to 141 in year ... percentage of patients with >1 hospitalization was evaluated for the prebaseline and postbaseline periods Percentages were tested with a McNemar test Categorical measures were summarized using frequencies...
Ngày tải lên: 11/08/2014, 16:20
Báo cáo y học: " Prevalence of metabolic syndrome in patients with schizophrenia, and metabolic changes after 3 months of treatment with antipsychotics results from a German observational study" doc
... the patients individual risk factors The prevalence of MetS in the FAS of 42.8% (AHA/ NHLB definition) at baseline was comparable to the findings from the CATIE study, which reported a baseline ... 36.0% in men and 51.6% in women (fasting cohort, N = 689); the higher risk for MetS in women was a universal finding in all age groups, races and ethnicities However, CATIE was a controlled clinical ... German sample of schizophrenia patients confirm the notion that MetS-prevalence is higher in patients with schizophrenia compared to the general population, with rates increasing with the duration...
Ngày tải lên: 11/08/2014, 16:20
Báo cáo y học: " Reduced peak oxygen uptake and implications for cardiovascular health and quality of life in patients with schizophrenia" ppsx
... changes in VO2peak after eight weeks of high aerobic intensity training in patients with schizophrenia [14] Recently, Strassnig et al [3] published measures of oxygen uptake in 117 patients with schizophrenia ... in clinical practice Finally, these finding represent an urging need for developing effective physical training interventions for patients with schizophrenia 16 Competing interests The authors ... Electro, Finland), respectively The protocol has previously been described in patients with schizophrenia as well as in healthy individuals [14, 16] The patients were carefully familiarized with the...
Ngày tải lên: 11/08/2014, 16:21
Báo cáo y học: " Post-injection delirium/sedation syndrome in patients with schizophrenia treated with olanzapine long-acting injection, I: analysis of cases" pdf
... seizure in either case The EEG findings for Cases and 14 were reported as normal In Case 9, which involved a patient with diabetes, the EEG showed a generalized slowing of waves corresponding with ... reported by patients at any time after the PDSS event was zero Post-recovery dosing In 13 cases, there was no change in dose following the PDSS event In cases, the olanzapine LAI dose was decreased ... around 1.0, indicating a small incremental increase in risk for each unit decrease in BMI (odds ratio = 0.92 [95% CI 0.86- Incidence During clinical trials of olanzapine LAI, 30 post-injection...
Ngày tải lên: 11/08/2014, 16:22