Particle development for drug delivery
... and Starting Materials 126 A3.3 Influence of Airflow Rate and Starting Materials 129 A3.4 Influence of the Length of Grinding Zone and Starting Materials 131 A3.5 Relative Importance of the Process ... versa The intensity of the light rings indicates the number of particles in the sample having a particular size range The positions and the state of motion of the individual particles not affect the ... shell of light and the shape of this shell is dependent on the size and the shape of the particle (Xu and Guida, 2003) The diffracted light is focused by a lens on a detector placed at the focal...
Ngày tải lên: 17/09/2015, 17:19
... advantage and which strikes not at the margins of the pro…ts and the outputs of the existing …rms but at their very foundations and their very lives.” Recently, Schumpeter’s vision of capitalism ... N There are no counterparts of Corollary and Corollary of Proposition Theorem in the following is the counterpart of Theorem Theorem (Restricted Short Sale) Assume ¹A ¡ ¹B > ½»§A and ¡1 l 0; the ... between ¡1 and +1, between payo¤s aM +N and bM ¡N, is determined by the coe¢cients a and b: The magnitude of ´ measures the degree of erosion of old knowledge Remark This assumption and the assumption...
Ngày tải lên: 07/03/2014, 02:20
... by the attachment of an activating form of S1, such as S1ADP The inset shows values of p2 as a function of the square root of the ionic strength The difference between the EGTA and Ca2+ rates are ... followed the predicted changes in the fraction of actin in the active state The agreement between the theoretical curves and the measurements was particularly good at higher ionic strengths where the ... as a function of the square root of the ionic strength Discussion Transitions between the inactive and active states of regulated actin are important determinants of the regulation of striated...
Ngày tải lên: 07/03/2014, 09:20
An Equilibrium Model of Rare-Event Premia and Its Implication for Option Smirks potx
... indeed of the form in Equation (E.27) Let J be the indirect utility function, which is a function of the state variables including the wealth process W and other state variables X affecting the endowment ... solution of jà 18 For the rest of our analysis, we will set the risk-free rate at r ¼ 5% and the dividend yield at q ¼ 3% In other words, we are not using the equilibrium interest rate and the dividend ... dynamic process than in the standard CRRA model, effectively does not price the diffusive and jump components of the endowment process differently.22 We therefore conjecture that, as formulated and...
Ngày tải lên: 07/03/2014, 10:20
Báo cáo khoa học: Monomeric molten globule intermediate involved in the equilibrium unfolding of tetrameric duck d2-crystallin pdf
... describes the dissociation/unfolding process of d2-crystallin Another possible origin of the discrepancy between the results of Sampaleanu et al [30] may be the denaturation time used in these protocols ... constant [5] The fit quality of the models was examined by the residuals and by minimization of the fit variance Results Dissociation of tetrameric d2-crystallin in GdnHCl A complex unfolding process ... ðVe À V0 Þ=ðVt À V0 Þ where, Ve is the elution volume of the protein elution peak and Vt and V0 are the total volume and the void volume of the column, respectively Analytical ultracentrifugation...
Ngày tải lên: 08/03/2014, 08:20
Báo cáo khoa học: Using directed evolution to improve the solubility of the C-terminal domain of Escherichia coli aminopeptidase P Implications for metal binding and protein stability pptx
... close to the N-terminus of the fragment ) it lies between the start of the fragment and the predicted start of the domain (Fig 1) From the round mutants, three were selected for further characterization: ... improving the solubility of the domain In the case of the AMPP protein, the boundary of the domain would have been better determined from an inspection of the structure rather than by the experimental ... and solubility assay The intact AMPP as well as the C-terminal fragments of AMPP were expressed in the same manner The genes were PCR amplified and cloned between the NdeI and EcoRI sites of the...
Ngày tải lên: 23/03/2014, 07:20
Báo cáo Y học: Extra terminal residues have a profound effect on the folding and solubility of a Plasmodium falciparum sexual stage-specific protein over-expressed in Escherichia coli pptx
... role of the D to N mutation; and (c) the role of the sequence and length of the C-terminal extension To address whether presence of extra residues at the N-terminal of Pfg27A were responsible for ... the central issue that solubility of fusion proteins is not necessarily indicative of either proper folding or of increased solubility of the protein of interest We propose that the success of ... further the structural elements responsible for the enhanced solubility phenomenon observed in Pfg27A, we identified three key issues: (a) the role of the N-terminal extension; (b) the role of the...
Ngày tải lên: 23/03/2014, 21:20
báo cáo hóa học:" Research Article Strong Convergence for Mixed Equilibrium Problems of Infinitely Nonexpansive Mappings Jintana Joomwong" pot
... for the minimization problem The results of this paper extend and improve the results of Zhao and He 14 and many others For some related works, we refer the readers to 15–22 and the references therein ... point of nonexpansive mappings, the set of solutions of an equilibrium problems, and the set of solutions of the variational of inequality Fixed Point Theory and Applications problem for an α-inverse ... element of the set of solutions of an equilibrium problem and the set of common fixed point of infinitely many nonexpansive mappings in H Let {Tn }∞ be a sequence of n nonexpansive mappings of C into...
Ngày tải lên: 21/06/2014, 10:20
Báo cáo hóa học: "Research Article Stability of Equilibrium Points of Fractional Difference Equations with Stochastic Perturbations" pdf
... is clear that the stability of the trivial solution of 2.2 is equivalent to the stability of the equilibrium point of 2.1 Together with nonlinear equation 2.2 we will consider and its linear ... region , the region where the point of equilibrium x2 is stable only green region and the region where the both points of equilibrium x1 and x2 are stable cyan region are shown in the space of p,q ... region where the points of equilibrium are absent white region , the region where both points of equilibrium x1 and x2 are there but unstable yellow region , the region where the point of equilibrium...
Ngày tải lên: 22/06/2014, 11:20
Báo cáo y học: "Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patients" potx
... designed the study, oversaw all aspects of the laboratory work, analyzed the data and prepared the manuscript SK, SA, MW and CB participated in the collection of clinical data and the recruitment of ... previously, the presence of the HLA-DRB1 SE was found to have no effect on the association of the PTPN22 1858T allele with the disease, since the frequencies of the PTPN22 1858T allele in RA patients and ... in both the patient and the control cohort and all analyzed subgroups The distribution of genotypes and the resulting allele frequencies of the variant PTPN22 1858T allele in RA patients and healthy...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Explicit equilibrium modeling of transcription-factor binding and gene regulation" pdf
... 150 bp 3' to the start of the ORF; the thin line plots a ROC curve for a regulatory region defined as the sequence between 1,000 bp and 500 bp 5' to the ORF The latter definition of the regulatory ... effect on the ROC curve This is because only the ranks of the genes are relevant to the curve, not the absolute occupancy of the gene by the transcription factor (There can be a modest effect of concentration ... occur, then a simple weight function can be used that assigns a weight of for adjacent sites and a weight of to all other sites The concentration of the dimer, [XY], is the product of [X], [Y], and...
Ngày tải lên: 14/08/2014, 14:22
Thermochemical equilibrium modeling of biomass downdraft gasifier: Stoichiometric models
... considered and then the values of a and b would be tested and modified if necessary Regarding the composition and LHV of the resulting synthesis gas, the influence of three gasification process parameters ... of the CO and produce H2 and CO2 The increase of the equivalence ratio, from 0.3 to 0.5, decreases the H2 and CO contents, and increases the CO2 content, being the global effect the decrease of ... Determination of the enthalpy of formation of feedstock is the second step, and knowledge of the HHV or LHV (low heating value) of the feedstock is necessary Applying the HHV definition the enthalpy of formation...
Ngày tải lên: 01/08/2016, 09:31
Study on the Photolytic Mechanisms of Red 141 Dye Wastewaters with an 185nm Vacuum-UV lamp
... disadvantage of the majority of the degradation processes introduced above is the need to add external agents into the aqueous medium In such situation, the effectiveness of the processes relies ... requirements of the VUV photolysis of water according to Eq (1) are related to the formation of high local concentration of hydroxyl radicals (OH.) and a series of other species (Gonzalez and Braun, ... NaOH and H2SO4 solutions The Red 141 and H2O2 and other chemicals used were reagent grade and all experimental solutions were prepared with deionized water The solution of Red 141 was added to the...
Ngày tải lên: 05/09/2013, 09:08
Tài liệu THE PRINCIPLES OF CHEMICAL EQUILIBRIUM doc
... determined by the relative speeds of these two reactions on the surface of the catalyst It is therefore a problem of rates and not of equilibria The theory of equilibria, based on thermodynamics, ... of states of liquid water, one member of each pair being on one side of the point of maximum density and the other member on the other side, each of which have the same density and the same pressure ... seen as follows: The possibility or impossibility of the processes A -+B and B-+ A depe'TU18 entirely on the nature of the Btates A and B and iB thus determined by the values of the variables, Buck...
Ngày tải lên: 12/02/2014, 16:20
Tài liệu Correspondence & Conversations of Alexis de Tocqueville with Nassau William Senior from 1834 to 1859, Vol. 2 docx
... resolution, and the bourgeoisie likewise; but what the nobles were instructed to demand was the boldest of all We talked of the letters of the writers of the eighteenth century, and of the correspondence ... unheard of in our history the honours and recompenses of a campaign for the butchery on the Boulevards Will not the other armies demand their share of work and reward? As long as the civil war in the ... of armed hands and its thousands of watching eyes The only opposition that is ventured is the abstaining from voting Whatever be the office, and whatever be the man, the candidate of the Prộfet...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khoa học: Mechanism of dihydroneopterin aldolase NMR, equilibrium and transient kinetic studies of the Staphylococcus aureus and Escherichia coli enzymes docx
... by the cleavage of the bond between 1¢ and 2¢ carbons of the substrate The epimerization product is generated by the re-formation of the C–C bond after the reorientation of GA, which exposes the ... addition of the enzyme, and the middle three spectra were obtained 18, 35, and 70 after the addition of the enzyme The top spectrum is that of DHMP for comparison Only the NMR signals of the 2¢ and 3¢ ... to the sizes of the Fig Stopped-flow analysis of the binding of HPO to SaDHNA The concentration of SaDHNA was lM, and the concentrations of HPO were 10, 20, 30, and 40 lM for traces 1, 2, 3, and...
Ngày tải lên: 19/02/2014, 00:20
On the Segregation of Genetically Modified, Conventional, and Organic Products in European Agriculture: A Multi-market Equilibrium Analysis doc
... to the returns to land (the fixed factor) At the demand level, the price of GM food of course decreases relative to the preinnovation choke price level The price of organic food decreases at the ... e i the demand level the only price that increases (relative to the baseline) is that of conventional food (the largest industry here) The production of organic food and of GM food both expand, ... demand and supply) in the three food markets Equation (28) accounts for equilibrium in the land market (demand for land from the three industries equals the exogenously given land endowment) and...
Ngày tải lên: 05/03/2014, 20:20
24,185 OUTLETS - The number of JApAN pOST BANk outlets in Japan docx
... Massive amount of Deposits the Largest Balance of Deposits in the World The Bank has the largest amount of deposits in the world, even in comparison with overseas banks, and is one of the world’s largest financial institutions ... We also have a distinctive product, TEIGAkU deposits. With these deposits, funds can be withdrawn at any time after six months from the inception of the deposit. The interest rate on TEIGAkU deposits is higher than the rate on ordinary deposits, and the interest rate at the point the deposit is made ... tionship, with the Bank acting primarily as the planning division and JApAN pOST NETWORk as the sales division The following pages illustrate the role the Bank is playing as it leverages and builds on this relationship with JApAN pOST NETWORk...
Ngày tải lên: 06/03/2014, 10:20
AN ECONOMIC HISTORY OF THE ENGLISH POOR LAW 1750-1850 pptx
... for the widespread adoption of outdoor relief policies in the 1770s and 1780s and for the significant differences in the administration of relief between the southeast of England and the west and ... hours at the Black Buoy, the Rose and Crown, the Horse and Groom, and the Flag passing on to me the famous oral tradition of the economics department (see O E Covick, "The Quantity Theory of Drink: ... who rented an acre or two of land had to feel the effects of engrossing Their land was taken away from them and added to the acreage of some large farm; and the farmer's land-hunger was so great...
Ngày tải lên: 07/03/2014, 03:20
Báo cáo Y học: The folding of dimeric cytoplasmic malate dehydrogenase Equilibrium and kinetic studies doc
... glutaraldehyde The enzyme concentration used was lgÆmL)1 (A) The photograph of the SDS/PAGE (10%) showing the different folding populations during the time course of refolding of s-MDH M is the band of the ... reflects the kinetics of reassociation of s-MDH as estimated from the relative peak areas of the scanned profile of the individual time points It shows two parallel pathways Most (70 ± 5%) of the monomers ... observation in the case of the equilibrium denaturation/renaturation of s-MDH, which indicated the molten globule nature of the intermediate One of the characteristic features of the molten globule...
Ngày tải lên: 08/03/2014, 23:20