rehabilitation of skeletal muscles in chronic obstructive pulmonary disease
báo cáo khoa học:"Comparison of health-related quality of life measures in chronic obstructive pulmonary disease" potx
... assessment and monitoring of COPD patient outcomes Abbreviations COPD: Chronic obstructive pulmonary disease; GOLD: Global burden of obstructive lung disease; HRQL: Health-related quality of life; FEV1: ... Organization: Chronic obstructive pulmonary disease. [http:// www.who.int/mediacentre/factsheets/fs315/en/index.html], Accessed February 10, 2011 Global Initiative for Chronic Obstructive Lung Disease: ... properties of the Spanish version of the SF-36 Health Survey among male patients with chronic obstructive pulmonary disease Quality of Life in COPD Study Group J Clin Epidemiol 1998, 51:1087-1094 Tsukino...
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Báo cáo y học: " A prospective study of decline in fat free mass and skeletal muscle strength in chronic obstructive pulmonary disease" pot
... marked in those with reduced fat free mass and declined further over the course of a year The only parameter predicting decline in QMVC during follow up was QMVC at baseline Of note the mean decline ... difference in the results obtained In addition it was possible in most patients to correlate their reports of exacerbations with the medical notes relating to clinic attendances in the intervening year ... decline is steady or if it is stepwise, perhaps in the context of exacerbations The pattern of decline may well differ in different disease phenotypes Our model explained only 46% of the decline...
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Báo cáo hóa học: "Analysis of airway secretions in a model of sulfur dioxide induced chronic obstructive pulmonary disease (COPD)" potx
... nitrate in a proportion of 1:2 to obtain the final working solution for staining of AgNORs The silver reaction carried out for 22–24 in the dark The sections were mounted in DPX without conterstain ... previously [52] One hour prior to termination of exposure, a single injection of 325 μl of 0.17 mM PBS-buffered BrdU (Boehringer, Mannheim, Germany) was administered intraperitoneally Sections were ... of allergic obstructive airway diseases such as allergic bronchial asthma [20], not exist In this respect, in striking contrast to numerous existing experimental approaches to determine the inflammation...
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báo cáo khoa học:" Predictors of health status do not change over three-year periods and exacerbation makes difference in Chronic Obstructive Pulmonary Disease" ppsx
... worsening of one unit of the BODE index has a 50% increased risk of worsening in the SGRQ total score and activity domain Our findings are in accord with Lin et al [11], who found by multiple linear ... baseline (Baseline Dyspnea Index) in order to answer questions regarding the TDI [28] Therefore, we used the MMRC scale which is a traditional instrument included in the BODE index [20] In multiple ... exacerbation in the changes of health status Our results showed that exacerbation rate was associated with impairment of HS during follow-up This finding reinforces the impact of exacerbation in clinical...
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Báo cáo y học: " Colour of sputum is a marker for bacterial colonisation in chronic obstructive pulmonary disease" pps
... Microbiologic determinants of exacerbation in chronic obstructive pulmonary disease Arch Intern Med 2005, 165:891-897 Miravitlles M: Exacerbations of chronic obstructive pulmonary disease: when are ... did not find increased sputum concentrations of pro-inflammatory cytokines in patients with bacterial colonisation Different reasons may explain this finding, including a small number of patients ... independent of a new strain acquisition In a prospective longitudinal cohort of COPD patients assessed during exacerbations and stable disease, sputum concentrations of pre-existing strains of...
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Báo cáo y học: " Oxidative modification of albumin in the parenchymal lung tissue of current smokers with chronic obstructive pulmonary disease" docx
... albumin Human serum albumin (HSA) is a single nonglycosylated polypeptide containing 35 cysteine residues all involved in the formation of stabilising disulphide bonds except 34cysteine In plasma, ... as a marker of protein degradation and turnover (8, 9) In fact the oxidative modification of proteins and lipids has been implicated in the etiology of a number of diseases including atherogenesis ... significant interaction of COPD with smoking (P < 0.001) Relationship between smoking status and levels of carbonylated HSA Since smoking status influenced baseline levels of HSA we next investigated...
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Báo cáo y học: " Efficacy and safety of once-daily aclidinium in chronic obstructive pulmonary disease" potx
... clinically meaningful [22]; assuming a baseline FEV1 of 1.29 L (the mean across treatment arms in this study), this corresponds to an increase of 64-129 mL Additional clinical studies of aclidinium ... Garcia GE, Ferrer P: Safety and pharmacokinetics of single doses of aclidinium bromide, a novel long-acting, inhaled antimuscarinic, in healthy subjects Int J Clin Pharmacol Ther 2009, 47:460-468 Chanez ... University of Modena and Reggio Emilia, Modena, Italy 7Division of Pulmonary Disease and Critical Care Medicine, School of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA...
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Báo cáo y học: "Two-year home-based nocturnal noninvasive ventilation added to rehabilitation in chronic obstructive pulmonary disease patients: A randomized controlled trial" pot
... consisted of 30-minute periods of cycling exercises, walking, and inspiratory muscle training each The cycling protocol consisted of intervals of one minute loaded cycling (aimed at 140% of a patient’s ... Prevention of COPD: Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2010 [http://www.goldcopd.org] Lacasse Y, Goldstein R, Lasserson TJ, Martin S: Pulmonary rehabilitation for chronic obstructive ... Groningen Leiden Universities Corticosteroids in Obstructive Lung Disease Study Group: Effect of fluticasone with and without salmeterol on pulmonary outcomes in chronic obstructive pulmonary disease: ...
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Báo cáo y học: "Dynamics of pro-inflammatory and anti-inflammatory cytokine release during acute inflammation in chronic obstructive pulmonary disease: an ex vivo study" pps
... 2C) Since neutralising the activity of IL-10 resulted in augmented release of TNFα, we next examined if there was a similar increase in the release of any other cytokines involved in the inflammatory ... determine the kinetic profile of release of the cytokines most reportedly elevated in COPD patients during exacerbations Figure of Severity COPD influences cytokine release Severity of COPD influences ... function decline in chronic obstructive pulmonary disease Thorax 2002, 57(10):847-852 Hurst JR, Perera WR, Wilkinson TM, Donaldson GC, Wedzicha JA: Exacerbation of chronic obstructive pulmonary disease: ...
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Báo cáo y học: " Skeletal muscle dysfunction in chronic obstructive pulmonary disease" pps
... changes include an increase in mitochondrial number, increased muscle capillarization, and an increase in muscle oxidative enzyme activity After intense training the proportion of type I fibers increases, ... Effect of pulmonary rehabilitation on physiologic and psychological outcomes in patients with chronic obstructive pulmonary disease Ann Intern Med 1995, 122:823–832 60 Goldstein RS, Gort ED, Stubbing ... independently of lung function [18] In one study [16], phosphofructokinase (a glycolytic enzyme that is involved in anaerobic metabolism) was significantly increased in patients with COPD, but this finding...
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Báo cáo y học: "Association of current smoking with airway inflammation in chronic obstructive pulmonary disease and asymptomatic smokers" pps
... insufficient to obtain a full view Fourth, remodelling in COPD may itself generate and maintain an inflammatory process, independent of cigarette smoking [25] In order to elucidate the role of ... inflammatory effects of current smoking may mask findings of chronic inflammation in COPD, since numbers of inflammatory cells in bronchial biopsies and sputum are comparable in smokers with mild COPD ... level of airway obstruction in COPD, suggesting that cumulative smoking induces chronic inflammation with subsequent sequelae of airway obstruction Our results indicate that inflammatory effects of...
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Báo cáo y học: "Pilot study of losartan for pulmonary hypertension in chronic obstructive pulmonary disease" ppt
... evaluation of pulmonary artery pressure in chronic obstructive pulmonary disease A European multicentre study Working Group on Noninvasive Evaluation of Pulmonary Artery Pressure European Office of the ... pathogenesis of pulmonary hypertension in COPD [3,8] although a number of other factors may be involved, including hyperinflation and loss of alveolar capillaries in emphysema [9] In addition, a degree of ... Atochina EN, Morris KG, Danilov SM, Stenmark KR: Angiotensin converting enzyme expression is increased in small pulmonary arteries of rats with hypoxia-induced pulmonary hypertension J Clin Invest...
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Báo cáo y học: "Abdominal muscle fatigue following exercise in chronic obstructive pulmonary disease" docx
... in healthy individuals [18,19] In COPD, the abdominal muscles are frequently recruited even during resting breathing [20] When walking to exhaustion, inspiratory work of breathing in COPD rises ... whom the distinction into inspiratory and expiratory is not absolute During exercise, at least in normal subjects, the expiratory muscles act as accessory muscles of inspiration by reducing end expiratory ... loading that the expiratory muscles are subject to during exercise in COPD, would lead to the development of abdominal muscle fatigue, assessed using the technique of magnetic stimulation of the...
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Báo cáo y học: " Systemic inflammation in chronic obstructive pulmonary disease: a population-based study" ppt
... any of the COPD stages [10] In contrast, an inverse association between higher levels of circulating inflammation-sensitive proteins, including CRP, interleukin (IL)-6 and alpha-1 antitrypsin ... Ben-Zaken Cohen S, Paré PD, Man SFP, Sin DD: The growing burden of chronic obstructive pulmonary disease and lung cancer in women Examining sex differences in cigarette smoke metabolism Am J Respir ... on systemic biomarkers of inflammation in chronic obstructive pulmonary disease Am J Respir Crit Care Med 2008, 177:1207-1214 Barnes PJ: Chronic obstructive pulmonary disease N Engl J Med 2000,...
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Báo cáo y học: " One-year treatment with mometasone furoate in chronic obstructive pulmonary disease" docx
... Care Med 2007, 176(6):532– 555 Chronic obstructive pulmonary disease National clinical guideline on management of chronic obstructive pulmonary disease in adults in primary and secondary care ... treatment with inhaled budesonide in persons with mild chronic obstructive pulmonary disease who continue smoking European Respiratory Society Study on Chronic Obstructive Pulmonary Disease N Engl ... Martin RJ: Inhaled corticosteroids reduce the progression of airflow limitation in chronic obstructive pulmonary disease: a meta-analysis Thorax 2003, 58(11):937–941 Effect of inhaled triamcinolone...
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Báo cáo y học: "Open Access Changes in elastin, elastin binding protein and versican in alveoli in chronic obstructive pulmonary disease" ppt
... staining in the both alveolar wall and alveolar Figure Lung sections stained for elastin, versican and elastin binding protein Lung sections stained for elastin, versican and elastin binding ... Figure Relationship between elastin binding protein and elastin Relationship between elastin binding protein and elastin Relationship between EBP immuno-staining intensities for alveolar wall (a) ... elastin receptor: a galactosidase-binding protein Science 1988, 239:1539-1541 Mecham RP, Whitehouse L, Hay M, Hinek A, Sheetz MP: Ligand affinity of the 67-kDa elastin/laminin binding protein is...
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Báo cáo khoa học: " Clinical review: Patient-ventilator interaction in chronic obstructive pulmonary disease" pps
... to maintain a constant Pappl, a change in any one of its determinants (Pmus or Paw) must be met by an opposite change in the other In clinical terms, this means that, for instance, increasing ... expiratory cycling [14], and, during NIV, a higher risk of gastric air intake and leaks [10] In the following paragraphs, we will examine the main aspects of these key determinants, following the time-course ... to decrease the triggering effort in a small group of patients without COPD, at the price of some degree of instability in the form of autotriggering [23] Another interesting technique is neurally...
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Báo cáo y học: "Recently published papers: Novel therapies in chronic obstructive pulmonary disease, cardiac chemicals and intensive care outcomes" ppt
... average of 1,034 kcal/day and 47 g protein/day An increase of Page of (page number not for citation purposes) Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease ... Rabe KF, Goehring U-M, Kristiansen S, Fabbri LM, Martinez FJ; for the M2-124 and M2-125 Study Groups: Roflumilast in symptomatic chronic obstructive pulmonary disease: two randomised clinical trials ... Groups: Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: two randomised clinical trials Lancet 2009, 374: 695-703 Reichlin T, Hochholzer...
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Báo cáo y học: "Another step for noninvasive ventilation in chronic obstructive pulmonary disease patients" pot
... the best conditions [8] In conclusion, extending the indication of NPPV use is always challenging and exciting It is unfortunate that the Page of preliminary successes of the Scala and colleagues ... risk–benefit ratio of such a strategy (NPPV combined with FBO in COPD with hypercapnic encephalopathy) in the most challenging patients Abbreviations COPD, chronic obstructive pulmonary disease; FBO, ... http://ccforum.com/content/14/3/163 mortality, duration of hospitalisation and duration of ventilation were similar in the two groups Despite the great interest of these findings for all practicing clinicians, the present study...
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Báo cáo y học: " Nitroglycerin can facilitate weaning of difficult-to-wean chronic obstructive pulmonary disease patients: a prospective interventional non-randomized study" pps
... day) nitroglycerin Nitroglycerin was administered by continuous intravenous infusion starting at the beginning of the spontaneous breathing trial, and its dose was titrated to maintain normal systolic ... in the setting of pre-existing coronary artery disease [10,13,20] A history of coronary artery disease was present in of our 12 patients (Table 1), and of the had findings of infarction on rest ... weaning, presumably by alleviating acute cardiac dysfunction Weaning-induced acute cardiac dysfunction resulting in acute pulmonary congestion is a known cause or cofactor of weaning failure in...
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