... Changes 1in plasma concentrations of cortisol Changes in plasma concentrations of cortisol Changes in plasma concentrations of cortisol (LSmean ± S.E.M.) in Boar-group (ᮀ), AI-group (x) and IUI-group ... Scand 1993, 34:109-16 Pettersson A, Einarsson S, Kindahl H: A study on the effects of inhibition of prostaglandin biosynthesis with flunixin meglumine and later administration of prostaglandin-F2-alpha ... prostaglandin F2α in the pig oviductal fluid Prostaglandins 1983, 25:413-424 Madej A, Mwanza AM, Kindahl H, Einarsson S: Effect of ACTH and CRH on plasma levels of cortisol and prostaglandin F2α...
Ngày tải lên: 12/08/2014, 18:22
... capable of overcoming a deficit in GLT1 function It is interesting in this regard that palmitoylation, a process by which proteins are inserted into cellular membranes [20], is reduced in HD mice, including ... WTs and R6/2s indicate saline treatment, and WTc and R6/2c indicate ceftriaxone treatment N refers to number of animals per group Genotype and CAG repeat length We used PCR for genotyping and ... blocking buffer Protein loading was normalized using b-tubulin immunoblotting as a loading control Chemiluminescent detection of HRP (SuperSignal West Pico; Pierce) was followed by exposure of...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo khoa học: "Effect of ACTH and CRH on Plasma Levels of Cortisol and Prostaglandin F2α Metabolite in Cycling Gilts and Castrated Boars" pdf
... al cate that prostaglandins in the brain interact in their stimulatory regulation of ACTH secretion Such an interaction may also be involved in prostaglandins mediation of the ACTH response to ... stimulation of porcine pituitary cells by relatively low concentrations of prostaglandin E2 support increased secretion of ACTH but exposure to greater concentrations of this prostaglandin in fact ... concomitant increase of cortisol and PGF2α metabolite levels in both cycling gilt as well as castrated boars The administration of CRH to pigs resulted in an elevation of cortisol levels in Effect of...
Ngày tải lên: 12/08/2014, 15:21
Regulation of navigation and vessel-source pollution in the Northern Sea Route - Article 234 and state practice
... 15 of the Economic Zone Edict; Arts and 15 of the Environmental Edict; and Art 11 of the Decree of the Council of Ministers of the USSR, June 1990, ‘On Measures of Securing the Implementation of ... within the inland waters, territorial sea or EEZ adjoining the USSR northern coast and that it includes seaways suitable for guiding vessels in ice Due to the vagueness concerning leading in Article ... the mandatory prescription of leading in ‘other regions’, as well as from Article 7(1) which states that the NSRA will determine the beginning and end of the navigational period taking into account,...
Ngày tải lên: 01/11/2013, 09:20
Tài liệu Báo cáo khoa học: Roles of AP-2 transcription factors in the regulation of cartilage and skeletal development doc
... role of AP-2a and AP-2e in chondrogenesis Overview of the differentiation stages during chondrogenesis and the involvement of transcription factors (henatoxylin and eosin-stained section of an ... tumorigenesis and genetic diseases [47] Most analyses of the regulation of AP-2 and the interactions of the transcription factor with binding partners, as well as of the regulation of target gene ... proline-rich and glutamine-rich N-terminus, which is important for transactivation, is shown in yellow, and contains the PY-motif (green) The helix–span–helix domain at the C-terminus shown in...
Ngày tải lên: 16/02/2014, 09:20
Báo cáo khoa học: Nuclear actin and actin-binding proteins in the regulation of transcription and gene expression docx
... contains an N-terminal domain harboring activation function 1, a central DNA-binding domain (DBD) and a C-terminal ligandbinding domain (LBD) containing activation function [67–70] Upon binding androgens, ... Actin and ABPs in transcription regulation B Zheng et al Table Role of nuclear actin-binding proteins interacting with the androgen receptor AR, androgen receptor; LBD, ligand-binding domain ... Direct a-actinin-2 ()) Bundling proteins Coactivator Supervillin NLS F-actin- and membraneassociated scaffolding protein Filamin NLS? Cross-linking proteins Filamin A NLS? Cross-linking proteins Transgelin...
Ngày tải lên: 07/03/2014, 01:20
Báo cáo khoa học: Huntington’s disease: roles of huntingtin-interacting protein 1 (HIP-1) and its molecular partner HIPPI in the regulation of apoptosis and transcription pptx
... containing inositol lipids and stabilizes the growth factor receptor tyrosine kinases by increasing their half-life following ligand induced endocytosis Such interaction affects cell growth and ... caspase-8-mediated pathway Rybp also interacts with ubiquitin-binding protein, procaspase-8, procaspase-10, and the HIPPI interactor apotin Interaction of HIPPI with Rybp is involved in murine neural development, ... resulting in aggregates ⁄ neuronal intranuclear inclusions Aggregates ⁄ neuronal intranuclear inclusions are observed in cell models, brains of transgenic animals, and post-mortem brains of HD...
Ngày tải lên: 23/03/2014, 07:20
Báo cáo Y học: Molecular characterization of MRG19 of Saccharomyces cerevisiae Implication in the regulation of galactose and nonfermentable carbon source utilization pdf
... monitored in MIG1 disruption (Fig 10, lane and 2) and wild-type (Fig 10, lane and 4) strains bearing multiple copies of MRG19 and grown in the presence of glucose (Fig 10, lane and 3) and glycerol ... digesting with SalI and filling in with dNTPs and the resulting plasmid was named p19C-S This construct was expected to induce a protein of 49 kDa To determine subcellular localizations of Mrg19p, ... gal80mrg19 strains Cells were grown to D600 of 0.5 in synthetic complete medium containing glycerol plus lactate and galactokinase activity was determined as described in Materials and methods MRG19...
Ngày tải lên: 31/03/2014, 08:20
báo cáo hóa học: " Proinflammatory and proapoptotic markers in relation to mono and di-cations in plasma of autistic patients from Saudi Arabia" docx
... resulting in increased permeability of the blood-brain barrier [46]; thus the administration of LPS to fetal sheep results in the extravasation of plasma proteins and macrophages into the brain ... treated standard solution of K + chloride in Bovine albumin equivalent to mol/L Page of Table Caspase3, IL6, TNFa, Ca2+, Mg2+, Na+ and K+ concentrations and Ca2+/Mg2+ and Na+/K+ ratios in plasma of ... impaired Ca 2+ and K + concentrations in plasma of autistic patients could be easily related to the postulated increase of brain cytokines (TNFa and IL6) after infiltration from plasma to brain Experimental...
Ngày tải lên: 19/06/2014, 22:20
Báo cáo khoa học: "Glutamate and GABA concentrations in the cerebellum of novel ataxic mutant Pogo mice" pdf
... endings [12] The present study examined that the concentrations of glutamate and GABA in the cerebellum of Pogo mouse Materials and Methods Animals Mice were generated from a breeding colony of ... (Dakopatts Inc., Mississauga, Canada) for hours at room temperature After three additional rinses in TPBS, antibody-binding sites were revealed by a 15 incubation in 0.2% diaminobenzidine in TPBS ... cells and their parallel fibers and, in consequence, to the formation of ‘heterologous’ mossy fiber contacts on Purkinje cells and a persistent multiinnervation of Purkinje cells by olivary climbing...
Ngày tải lên: 07/08/2014, 17:22
Báo cáo y học: "T-cell contact-dependent regulation of CC and CXC chemokine production in monocytes through differential involvement of NFκB: implications for rheumatoid arthritis" docx
... transcription factor NFκB, in order to gain insight into the regulation of chemokines at sites of inflammation Materials and methods Isolation of peripheral blood monocytes and lymphocytes Human monocytes ... RANTES and MCP-1 was unaffected (Figure 2c) This inverted pattern of utilization of NFκB for the T-cell contact-dependent induction of CC and CXC chemokines in monocytes is surprising and indicates ... factor binding elements in activating the interleukin-8 gene by pro-inflammatory cytokines J Biol Chem 1990, 265:21128-21133 42 Wood LD, Richmond A: Constitutive and cytokine-induced expression of...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo y học: "Regulation of pathogenic IL-17 responses in collagen-induced arthritis: roles of endogenous interferon-gamma and IL-4" pot
... attenuation of autoimmunity Herein we present data on the regulation of IL17 responses by the Th1 cytokine IFN-γ and the Th2 cytokine IL-4 in CIA treatments Hematoxylin and eosin staining of paws ... study demonstrating that Th17 cells were predominant in the draining inguinal lymph nodes whereas IL-17-producing γδ T cells were predominant in the inflamed joint [27] Although increased systemic ... Goldman M, Berg WB van den: Role of interleukin-4 and interleukin-10 in murine collagen-induced arthritis Protective effect of interleukin-4 and interleukin-10 treatment on cartilage destruction...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo khoa hoc:" Unexpected depletion in plasma choline and phosphatidylcholine concentrations in a pregnant woman with bipolar affective disorder being treated with lithuim, haloperidol and benztropine: a case report" pptx
... and are actively transported to the foetus [1,11] The decreases in plasma concentrations of these nutrients in our patient were unexpected, as plasma concentrations of both are increased during ... diminished concentrations of choline and its metabolites in rat liver J Nutr 1995, 125:3049-3054 Ozarda Ilcol Y, Uncu G, Ulus IH: Free and phospholipid-bound choline concentrations in serum during ... factor in this case, as the patient maintained normal plasma concentrations of haemoglobin throughout the pregnancy Low weight gain during pregnancy is another risk factor that contributes to low infant...
Ngày tải lên: 11/08/2014, 10:23
báo cáo khoa học: " Genetic and transformation studies reveal negative regulation of ERS1 ethylene receptor signaling in Arabidopsis" pot
... measurement of mutants respectively carrying and lacking ERS2 (C) phenotype and (D) hypocotyl measurement of etiolated seedlings of ers1-2 etr2 ein4, ERS1p:ERS1 ers1-2 etr2 ein4, and etr2 ein4 Error ... alterations in the expression of the remaining receptor genes (Figures 2C, 2D, and 2E) Notably, ETR1 expression in etr2 ein4 ers2 was identical to that in ers1-2 etr2 ein4 ers2 and ers1-3 etr2 ein4 ers2 ... a numerically larger value of t air: seedlings germinated in air; AVG: seedlings germinated in the presence of AVG ein4 ers2 ers1 etr2 ers2 exhibited early flowering and rosette growth ceased...
Ngày tải lên: 12/08/2014, 03:21
Báo cáo y học: "Oxygen-sensing mechanisms and the regulation of redox-responsive transcription factors in development and pathophysiology" ppsx
... (blocked arrows) of different stages in the proposed pathway are indicated Genistein is an inhibitor of tyrosine protein kinase and competitive inhibitor of ATP in other protein kinase reactions; ... signaling and proinflammatory cytokines [13,14,16–18] This review is primarily concerned with discussing the recent understanding of redox signaling and gene regulation, the role of oxygenation in ... nucleus, pull NF-κB off DNA, and export NF-κB back to its resting state in the cytoplasm Thick lines indicate the activating pathway; thin lines indicate the inactivating pathway IκB-independent pathways,...
Ngày tải lên: 12/08/2014, 18:20
Báo cáo y học: "The effects of dopamine and epinephrine on hemodynamics and oxygen metabolism in hypoxic anesthetized piglets" potx
... dopamine or epinephrine and was administered all three doses, which were selected in random order as determined by a LatinSquare method Dopamine and epinephrine were infused at doses of 2, 10, and ... significantly increased at the final 30 of 3.2 µg kg–1 min–1 epinephrine infusion (Fig 4) There was no significant increase in SAP at this epinephrine dose The SAP/PAP ratio was not changed with epinephrine ... dopamine and epinephrine are commonly used medications in the treatment of shock and hypotension in sick newborns Our study is the first that compares the effects of dopamine and epinephrine infusions...
Ngày tải lên: 12/08/2014, 18:21
Báo cáo khoa học: "Luminal concentrations of L- and D-lactate in the rectum may relate to severity of disease and outcome in septic patients" ppt
... shown in Table 1, and selected clinical variables during study are shown in Table Luminal and plasma concentrations of L-lactate Rectal luminal concentrations of L-lactate were increased in non-survivors ... admission, and sequential organ failure assessment (SOFA) score was calculated from values of the preceding 24 hours Concentrations of L- and D-lactate in rectal lumen and plasma The concentrations of ... al Figure Figure Luminal concentrations of L-lactate (a) and D-lactate (b) in non-surviving and surviving septic patients and healthy subjects and surviving septic patients and healthy subjects...
Ngày tải lên: 13/08/2014, 03:20
Báo cáo y học: " Signaling and regulation of G protein-coupled receptors in airway smooth muscle" ppsx
... relaxation of methacholine-induced bronchoconstriction, but an increase in GRK activity, and GRK2 and GRK5 expression in the lung [112] This is an intriguing finding and suggests that inflammation ... for examining agonist-induced changes in stiffness of cultured ASM cells that has provided useful information linking regulation of GPCR signaling with ASM contractile state [23] Interestingly, ... Chiu CT, Lin CC, Luo SF and Hsiao LD Interleukin-1beta enhances bradykinin-induced phosphoinositide hydrolysis and Ca2+ mobilization in canine tracheal smooth-muscle cells: involvement of the Ras/Raf/...
Ngày tải lên: 13/08/2014, 13:20
Báo cáo y học: "Advances in understanding the regulation of apoptosis and mitosis by peroxisome-proliferator activated receptors in pre-clinical models: relevance for human health and disease" potx
... hepatocytes In support of the role of TNFα as a key mediator in the stimulation of hepatocellular proliferation, recent findings suggest that down -regulation of the iron-binding protein lactoferrin (LF) ... the AF2 ligand-dependent activation domain The amino-terminal A/B domain contains the AF1 ligand-independent activation domain The D domain consists of a highly flexible hinge region and non-rodent ... MAP-kinase mediated phosphorylation of Ser112 of mouse PPARγ2 lowers transcriptional activity [14,15] The ligand binding domain (LBD), or E/F domain of PPARs, is responsible for ligand-binding and...
Ngày tải lên: 13/08/2014, 13:20
Báo cáo y học: "Global analysis of alternative splicing regulation by insulin and wingless signaling in Drosophila cells" ppt
... Activation of insulin and wingless signaling pathways in Drosophila S2 cells Figure Activation of insulin and wingless signaling pathways in Drosophila S2 cells (a) Schematic representation of the insulin ... changes in alternatively spliced mRNA isoforms induced by insulin and wingless Figure Numerous changes in alternatively spliced mRNA isoforms induced by insulin and wingless (a) Features of microarray ... Insulin regulates alternative splicing of protein kinase C beta II through a phosphatidylinositol 3-kinasedependent pathway involving the nuclear serine/argininerich splicing factor, SRp40, in...
Ngày tải lên: 14/08/2014, 21:20