regulation of acid base balance

... positively influence common markers of hydration status under free-living conditions Thus, the potential influence of AK water on Page of 12 markers of both acid- base balance and hydration status were ... P: Effect of a supplement rich in alkaline minerals on acid- base balance in humans Nut J 2009 11 Welch AA, Mulligan A, Bingham SA, Khaw K: Urine pH is an indicator of dietary acid- base load, ... concentrations of calcium and bicarbonate, can impact acid- base balance [6] and contribute to the prevention of bone loss [7] In fact, Burckhardt [7] has suggested that the purposeful consumption of mineral...

Ngày tải lên: 11/08/2014, 23:21

... sporting context Therefore, the aim of this preliminary study was to profile the acid- base response after ingestion of a manufacturer recommended, acute dose of fruit and vegetable extract and ... lack of an acute alkalotic shift in acid- base balance contrasts with other recently published work by König and colleagues [3] These researchers presented Figure Represented are the acid- base ... Effect of a supplement rich in alkaline minerals on acid- base balance in humans Nutr J 2009, 8:23-30 Adevia MM, Souto G: Diet-induced metabolic acidosis Clin Nutr 2011, 30:416-21 Minich DM: Acid- alkaline...

Ngày tải lên: 11/08/2014, 23:21

... Acid- Base abnormalities  Metabolic Acidosis  Metabolic Alkalosis  Respiratory Acidosis  Respiratory Alkalosis Mechanisms of acid- base balance Respiratory system ... of ↑AG metabolic acidosis: “Accumulation of acids” lactic acidosis Ketoacidosis - diabetic, alcoholic, starvation Toxins - ethylene glycol, methanol, salicylates RF - acute & chronic Causes of ... Titrable acids (HPO4) Excretion of organic acids Buffers Ca, Hb, PP bones Ammonium (NH4) Metabolic Acidosis  Definition:  Primary decrease in serum HCO3  Decreased pH  Accumulation of acids...

Ngày tải lên: 20/01/2014, 05:21

... Madias NE: Medical progress: management of life-threatening acid- base disorders: second of two parts N Engl J Med 1998, 338:107-111 Worthley LIG: Acid base balance and disorders In Oh’s Intensive ... the SID values of commercially available weak acid colloids are all significantly greater than zero (Table 6) On infusion, the raised SID will tend to offset the acid base effects of ATOT infusion ... tendency of standard albumin and gelatin based colloids to cause metabolic acidosis is probably similar to that of saline By contrast, hetastarch and pentastarch are not weak acids, and the SID of...

Ngày tải lên: 12/08/2014, 20:20

... The A.B.C of Acid Base Chemistry Chicago: University of Chicago Press; 1974 27 Singer RB, Hastings AB: Improved clinical method for estimation of disturbances of acid- base balance of human blood ... preparation of the manuscript Wooten EW: Analytic calculation of physiological acid base parameters J Appl Physiol 1999, 86:326-334 Stewart PA: How to understand acid base balance In A Quantitative Acid Base ... calculation of the relevant blood acid base data Scand J Clin Lab Invest 1960, 12:177 Siggaard-Andersen O: Blood acid base alignment nomogram Scales for pH, PCO2, base excess of whole blood of different...

Ngày tải lên: 12/08/2014, 20:20

... type of acid base abnormality, are not capable of quantifying the amount of acid or base that has been added to the plasma unless PCO2 is held constant This observation prompted the development of ... SBE, standard base excess; SID, strong ion difference; SIG, strong ion gap parity can be brought to all three acid base approaches This is because acid base balance in plasma is based upon thermodynamic ... component of an acid base abnormality In 1948, Singer and Hastings [22] proposed the term ‘buffer base to define the sum of HCO3– and the nonvolatile weak acid buffers A change in buffer base corresponds...

Ngày tải lên: 12/08/2014, 22:22

... levels of SIG may be seen in the absence of acid base abnormalities using traditional acid base measurements (e.g PCO2, standard base excess [SBE], pH) We recently compared quantitative acid base ... classifications of metabolic acidosis have on patient outcome Hyperchloremic metabolic acidosis Even though many causes of metabolic acidosis may be unavoidable, often the source of metabolic acidosis ... determination of the primary etiology of a metabolic acidosis In the presence of a metabolic acidosis and a normal lactate and SIDa, the resulting charge balance must be composed of unmeasured...

Ngày tải lên: 12/08/2014, 22:22

... medical library Competing interests The author declares that they have no competing interests Page of (page number not for citation purposes) ...

Ngày tải lên: 13/08/2014, 16:21

... ACID- BASE BRØNTED-LOWRY • Acid: chất cho proton H+ • Base: chất nhận proton H+ H O + H Cl H Base Acid (proton acceptor) (proton donor) + H O H + Cl - H Conjugate acid Conjugate base of HCl of ... dạng acid mạnh (pKa nhỏ) dạng base liên hợp yếu ngược lại Cân Acid- Base Trong phản ứng acid- base: dạng acid mạnh phản ứng với dạng base mạnh cho sản phẩm dạng acid base yếu O O H3C C O pKa = 4.74 ... BASES • Acid Base cứng (hard): Kích thước nhỏ, phân cực hóa • Acid Base mềm (soft): Kích thước lớn, dễ bị phân cực hóa • Khuynh hướng tương tác: acid cứng với base cứng acid mềm với base mềm...

Ngày tải lên: 25/08/2016, 15:34

... These results confirm the participation of ACS4 and of AA-CoA in the regulation of steroidogenesis in Y1 cells DISCUSSION AA is present in the plasma membrane of most mammalian cells esterified to ... compartment of the cell upon hormone treatment Taken together the results shown here demonstrate the critical role of acyl-CoA synthetases and thioesterases in the regulation of intracellular levels of ... (2000) Regulation of arachidonic acid release in steroidogenesis: role of a new acyl-CoA thioesterase (ARTISt) Endocr Res 26, 653–662 Tomoda, H., Igarashi, K & Omura, S (1987) Inhibition of acyl-CoA...

Ngày tải lên: 08/03/2014, 09:20

... Regulation of secretases by retinoic acid A Koryakina et al use of several potential PKC activators, such as phorbol esters Therefore, an assessment of the action of RA(s) in AD ... patients, as retinoids have a long history of clinical use [11,12] To elucidate the regulation of secretases, we examined the effect of all-trans-retinoic acid (ATRA) on a-secretase [a disintegrin ... FEBS 2647 Regulation of secretases by retinoic acid A A Koryakina et al B Fig ATRA treatment activated PKCs and caused increased secretion of sAPPa in IMR-32 cells (A) Phosphorylation of PKC was...

Ngày tải lên: 16/03/2014, 01:20

... the regulation of GnRH II gene by RARs, TE671 and JEG-3 cells were treated with all-trans retinoic acid (ATRA; a ligand of RARs) and ⁄ or 9-cisRA (a ligand of RXRs) before the measurement of GnRH ... transcriptional regulation of the hGnRH II It is also the first report of differential regulation of the gene in two GnRH IIexpressing cell types It may give useful cues about the expression pattern of the ... simultaneous ligand activation of RARa and RXRa (cotransfection of RARa and RXRa together with treatment of both ATRA and 9-cisRA) provided further up -regulation of the promoter activity (P

Ngày tải lên: 16/03/2014, 10:20

... oleic acid appears to be a protein constituent at any pH (see below), we favour pH-independent binding of the fatty acids to Rv2212 The kinetic bases of the fatty acid and pH-sensing responses of ... stimulation of Rv1264 by added fatty acids (see above) In light of the data Mycobacterium tuberculosis AC Rv2212 Fig Models of stimulation of Rv2212 by fatty acids (A) Schematic representation of Rv2212 ... CHD of 177 amino acids shares 29% identity with that of Rv1264 (41% similarity; for alignments see [20]) The N-terminus of Rv2212 has 211 amino acids and is 21% identical (31% similar) to that of...

Ngày tải lên: 30/03/2014, 10:20

... right Lower panel, RT-PCR analysis of cDNA of the same samples as in (C, upper panel) The expected sizes of the amplicons (199 base pairs for FAAH and 258 base pairs for 18S rRNA) are indicated ... presence of 100 nM ÔcoldÕ leptin (data of the ÔcoldÕ leptin experiment with CHP100 cells were superimposable to those of U937 cells, and were omitted for the sake of clarity) Western blot analysis of ... were increased by treatment of U937 cells, but not of CHP100 cells, for 24 h with lM progesterone (Fig 3B) Quantitative analysis of phospho-STAT3 and of total Ikaros isoforms by ELISA corroborated...

Ngày tải lên: 30/03/2014, 15:20

... perturbations consisting of ramp-andhold tilts of 8° (peak velocity of 36°/s) in each direction of the pitch and roll planes Visual perturbations were induced by sudden movements of a virtual environment ... rapid and profound effect on postural responses [10,11] The influence of moving visual fields on postural stability depends on the characteristics of the visual environment, and of the support ... size of the base of support, its rigidity or compliance [12,13] Within physiological limits, a central recalibration process exists to produce appropriate responses even in the presence of sensory...

Ngày tải lên: 19/06/2014, 10:20

... Upon administration of retinoic acid, NF-κB activity is reduced, which suggests an effect of RARs on function rather than expression of NF-κB Recombinant NF-κB p65 and members of both the RAR and ... the ratio of the band intensity of NF-κB p65 or RARα to that of β-catenin that served as a loading control Suspended chondrocytes were transfected with equal amounts of DNA (0.052 μg of each vector ... treated with both TNF-α and atRA Regulation of transcription factor activity by p300 Differences in the affinity for p300 may contribute to the pattern of regulation of transcription factor activity...

Ngày tải lên: 09/08/2014, 10:22

... prevention of carcinogenesis, in non-cancerous animal- and cell-based studies [22-24] These studies support the potential utility of LA as an anticancer agent and the importance of the elucidation of ... novel role of cyto- Page of (page number not for citation purposes) Journal of Hematology & Oncology 2008, 1:4 http://www.jhoonline.org/content/1/1/4 Figure Proposed mechanism of action of LA Proposed ... antioxidant actions of alpha-lipoic acid in endothelial cells Free Radic Biol Med 2002, 33:83-93 Packer L, Kraemer K, Rimbach G: Molecular aspects of lipoic acid in the prevention of diabetes complications...

Ngày tải lên: 10/08/2014, 22:20

... conclusion, the typical acid base picture of ARF of critical illness is one of mild acidemia due to moderate metabolic acidosis Such acidosis is the result of the net balance of acidifying forces due ... achieve a better understanding of the nature of the acid base disorders of ARF in critically ill patients To achieve this goal, we sought to define and quantify acid base disorders in these patients ... Other factors affecting acid base balance To define the unique acid base characteristics of ARF patients, we used two control groups The matched control group consisted of 40 ICU patients without...

Ngày tải lên: 12/08/2014, 19:22

... effect of replacement fluid on acid base balance, and the effect of HVHF on acid base balance A strong focus is given to the clinical implications of these interventions, with the aim of helping ... the presence of acidifying anions to those clinicians using conventional acid base analysis Effect of renal replacement therapy on acid base balance There are two major modalities of RRT One is ... manage the acid base disorders in ARF and critically ill patients in general Acid base analysis using the Stewart–Figge methodology As described above, the pathogenesis of acid base disorders of ARF...

Ngày tải lên: 12/08/2014, 20:20

... popular among acid base physiologists since about 1955 [5,9] However, some of the most important developments in the evolution of acid base physiology occurred before the publication of the Bronsted–Lowry ... Hastings [14] introduced the buffer base in 1948 in an attempt to identify acid base changes independent of carbon dioxide The buffer base is the sum of weak acid (buffer) anions in plasma including ... to the ‘Great Trans-Atlantic Acid Base Debate’ [25] Instead of base excess the Americans offered six ‘rules -of- thumb’ to correct changes in the partial pressure of carbon dioxide or bicarbonate...

Ngày tải lên: 12/08/2014, 20:20