... [11-13] A total of measurements of the plasma concentration of 5-FU were made per patient, and it was concluded that the average value was predictive of clinical response, but not of severe acute ... when all of the following criteria were satisfied on observation of the entire esophagus: 1) disappearance of the tumor lesion; 2) disappearance of ulceration (slough); and 3) absence of cancer ... Episodes of severe acute leucopenia, stomatitis and cheilitis occurred in 42.9%, 12.5% and 14.3% of cases, respectively, and each rate was independent of disease stage (data not shown) Replacement of...
Ngày tải lên: 26/10/2012, 09:53
... view of the world that is heading toward John Sailhamer: ECLIPSE OF OLD TESTAMENT NARRATIVE 81 its conclusion That is, in fact, the blessed hope of the Christian The return of Christ is the end of ... Liberalism's view of the religion and theology Nelson Goodman, Ways of Worldmaking, Indianapolis: Hackett Publishing Company, 1978 John Sailhamer: ECLIPSE OF OLD TESTAMENT NARRATIVE 67 of the Bible, ... of the dispensations noted in the Scofield Bible At either end of the chart there was a half-circle which represented "eternity past" and "eternity future." In the middle of these two parts of...
Ngày tải lên: 19/02/2014, 14:20
Tài liệu Báo cáo khoa học: Insights into the interaction of human arginase II with substrate and manganese ions by site-directed mutagenesis and kinetic studies Alteration of substrate specificity by replacement of Asn149 with Asp docx
... view of these results, at least gross structural changes can be discarded as a consequence of the mutagenic replacements Effects of the His120Asn and His145Asn mutations on the affinity of metal ... only about 5% of the arginase activity of the wildtype enzyme As measured by kcat ⁄ Km, the catalytic efficiency of the Asn149Asp variant was found to be about 36-fold lower than that of wild-type ... arginase I [9] Differences in the binding of the a-carboxylate and a-amino groups of BEC were also ascribed to the larger volume of the active site cleft of arginase II, which allows more water-mediated...
Ngày tải lên: 20/02/2014, 02:21
Tài liệu The Fundamental Principles of Old and New World Civilizations docx
... Univ of Pennsylvania; Corresponding Member of the Antiquarian and Numismatic Society of Philadelphia; of the Anthropological Society of Washington; of the Societỏ Italiana d'Antropologia; of the ... however, glimpses of the shadowy form of an invisible and venerable female ruler who is at the head of the "House of Women," watches over the welfare of the women of the tribe and officiates as a ... chiefs or representatives of the four quarters of the City of Mexico In each of these quarters there was a place where periodical offerings were made in reverence of one of the signs: acatl, tecpatl,...
Ngày tải lên: 21/02/2014, 11:20
Tài liệu England in the Days of Old docx
... under the title of "The Corporation Plate and Insignia of Office, &c., of the Cities and Towns of England and Wales," will be found particulars of snuff-boxes belonging to some of the older municipal ... portrait of the Earl of Albemarle wearing one In the picture of the House of Commons in the time of Sir Robert Walpole we get an excellent indication of how England in the Days of Old, by William ... loaves of sugar, which were presented to Mr Recorder £1 10s 0d." England in the Days of Old, by William Andrews 21 The records of the city of Winchester include particulars of many presents of sugar...
Ngày tải lên: 21/02/2014, 21:20
Tài liệu Dulcibel A Tale of Old Salem pdf
... in the Truth of Christ After the trial and conviction of Bridget Bishop, the Special Court of seven Judges a majority of whom were leading citizens of Boston, the Deputy Governor of the Province, ... excitement of these days was enough to drive the more excitable portion of the inhabitants of Salem almost crazy The work of the house and of the farm was neglected; a large number of suspected ... grief, the families of some of the imprisoned knew not where to get their daily food; for their property was generally taken possession of by the officers of the law at the time of the arrest, the...
Ngày tải lên: 21/02/2014, 21:20
Báo cáo khoa học: Replacement of two invariant serine residues in chorismate synthase provides evidence that a proton relay system is essential for intermediate formation and catalytic activity docx
... amino acid replacements significantly affected the utilization of NADPH as a source of reducing equivalents for activation of the cofactor to its reduced form Chorismate synthase activity of the serine ... those of the wild-type protein The two-step chromatographic procedure developed for the purification of wild-type enzyme yielded similar amounts of the mutant proteins (3 mg of protein per gram of ... (Table 1) was similar to that of the wild-type enzyme, whereas the replacement of Ser16 with alanine resulted in a slight increase of the dissociation constant (inset of Fig and Table 1) Similarly,...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: Molecular basis of perinatal hypophosphatasia with tissue-nonspecific alkaline phosphatase bearing a conservative replacement of valine by alanine at position 406 Structural importance of the crown domain potx
... analysis of a purified GPI-anchorless soluble version of the mutant protein The Kcat ⁄ Km value of the mutant TNSALP was less than one-tenth of the Kcat ⁄ Km value of the soluble form of the wild-type ... containing the SV40 early promoter [11] Shortage of a precursor of GPI in the endoplasmic reticulum may be one of the reasons why a small but significant fraction of the wild-type TNSALP forms the aggregate ... supporting that the folding and assembly process and subsequent intracellular trafficking of TNSALP (V406A) are largely normal in the stable cell line Kinetics of the soluble form of TNSALP (V406A)...
Ngày tải lên: 07/03/2014, 05:20
The Customs of Old England docx
... The Customs of Old England, by F J Snell The Customs of Old England, by F J Snell The Project Gutenberg EBook of The Customs of Old England, by F J Snell This eBook is for the use of anyone anywhere ... the Seal of the Office of the Chancellery of the aforesaid University on the fifth day of the month of July in the fourteenth hundred and sixtieth year of our Lord." From the wording of this letter-testimonial ... comparative youth, of some of the postulants Mary, the widow of Lewis, King of Hungary, was only twenty-three at the time of her profession Our English annals yield striking instances of promises followed...
Ngày tải lên: 08/03/2014, 18:20
Báo cáo khoa học: Replacement of helix 1¢ enhances the lipid binding activity of apoE3 N-terminal domain pot
... absence of competitor ligand (corresponding to 23 742 c.p.m per mg cell protein) was taken as 100% (bar 1) Binding in the presence of competitors is expressed as percentage of control Incubations of ... competitor ligand 125I-labeled LDL binding in the absence of competitor (labeled LDL alone) was taken as 100% (Fig 5) Inclusion of a 50-fold excess of unlabeled LDL (50· unlabeled LDL) resulted in a ... role, serving to maintain the integrity of the helix bundle in the absence of lipid, perhaps by contributing to sequestration of the hydrophobic interior of the protein FEBS Journal 273 (2006)...
Ngày tải lên: 30/03/2014, 11:20
Havelok The Dane A Legend of Old Grimsby and Lincoln docx
... the Dane One of the most curious proofs of the actual British origin of the legend is in the statement that the death of Havelok's father occurred as the result of a British invasion of Denmark ... distinctly Norse name of Hodulf The claim for conquest of the north by Arthur is very old, and is repeated by Geoffrey of Monmouth, and may well have originated in the remembrance of some successful ... names of Danish kings, that it was before the first days of the greatness of Ethelbert of Kent, the overlord of all England, the Bretwalda, and therefore, as Father Wislac counts, about the year of...
Ngày tải lên: 31/03/2014, 21:20
the economics of adaptive reuse of old buildings a financial feasibility study & analysis
... and even older suburb has these types of properties They vary from the single vacant site to surface parking lots to empty old industrial building Often located in the core sections of urban ... walking distance of residents Within the neighborhood there are a variety of housing types and land uses, a mix of shops, services, and civic uses capable of satisfying many of the residents; ... availability of liability insurance; - the lack of information and funding with respect to orphan sites; - the lack of information of the current environmental condition of the land; - the lack of public...
Ngày tải lên: 03/06/2014, 02:15
Book of market data Types of market data Getting market data potx
... Chartoasis.com: Book of market data Types of market data Types of market data Market data are different in many ways Let's talk about the categorization by content, language & country, and the form of data! ... price of the first trade within a minute interval, the closing price is the last one, the volume is the sum of the trade volumes over the minutes etc There are two main types of this kind of data: ... see some of the possible relations: 3.2 Timestamps and dates Timestamp means the time of an event, like the time of a transaction or the time of a change in the order book Date is a kind of timestamp,...
Ngày tải lên: 27/06/2014, 23:20
Báo cáo toán học: " The Number of [Old-Time] Basketball Games with Final Score n:n where the Home Team was never losing but also never ahead by more than w Point" pot
... touches the minimum of i and j only at the corresponding endpoint [ij] We will need various kinds of generating functions in the proof Let fw (z) denote the [ij] generating function of the [ij] walk ... slightly modified Following the steps of the previous proof yields the result the electronic journal of combinatorics 14 (2007), #R19 Numerators and Denominators of Fw Using (8), we will now derive ... (8) Remarks For the sake of completeness, we give references to the number of such basketball games for various values of w For w = 2, · · · , and w = ∞, the sequence of games ending at n : n...
Ngày tải lên: 07/08/2014, 15:22
Báo cáo y học: "Reduced transforming growth factor-beta signaling in cartilage of old mice: role in impaired repair capacity" ppsx
... mice and lateral tibial cartilage of month and year old C57Bl/6 mice Paraffin sections of knee joints of young (5 months old) and old (2 years old) mice were stained with hematoxylin and eosin ... Percentage oflateralexpressing transforming growth factor (TGF)-beta in medial and lateral tibial cartilage Paraffin sections of knee joints of young (5 months old) and old (2 years old) mice ... (TGF-betaRs) Percentage of cells expressing transforming growth factor (TGF)-beta receptors (TGF-betaRs) Paraffin sections of knee joints of young (5 months old) and old mice (2 years old) were stained...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: " Sociodemographic and occupational risk factors associated with the development of different burnout types: the cross-sectional University of Zaragoza study" docx
... characteristics that are congruent with the definition of each of the subtypes The results of this work assist the clinical differentiation of subtypes by introducing sociodemographic and occupational ... differential impacts of the various types of organisations on their employees [57,58] and to the personal relations and forms of communication established in the workplace [36], some of which offer protection ... to the understanding of the type of professional burnout present in employees of a university organisation in Spain and support the idea of a differential characterisation of burnout syndrome...
Ngày tải lên: 11/08/2014, 15:22
báo cáo khoa học: " Effect of age, impaction types and operative time on inflammatory tissue reactions following lower third molar surgery" pdf
... associated with the least degree of facial swelling and best mouth opening among the types of impaction A multivariate analysis of the effect of patients’age, sex, type of impaction and operative time ... Interaction of operative time and type of impaction had the highest eigenvalue of 2.66 compared to other factors matrix tests, indicating that the interactions of operative time and types of impaction ... interrelation of complaints after removal of impacted mandibular third molars The duration of operation in the hand of a single surgeon could be a reflection of the difficulty and hence duration of tissue...
Ngày tải lên: 11/08/2014, 20:21
Báo cáo khoa học: "The ORF59 DNA polymerase processivity factor homologs of Old World primate RV2 rhadinoviruses are highly conserved nuclear antigens expressed in differentiated epithelium in infected macaques" pps
... ORF59 homologs of members of the RV1 and RV2 lineages of KSHV-like rhadinoviruses from chimpanzee and three species of macaques We obtained the complete sequences of the ORF59 homologs of the RV1 ... Comparison ofprevious page) Comparison of the ORF59 homologs of Old World primate RV1 and RV2 rhadinoviruses The orf59 genes from the RV1 rhadinoviruses from chimpanzee (PtrRV1) and three species of ... the production of infectious virus [26] A genome-wide transcription profile and a more restricted profile of several key RRV genes have been determined during the time course of infection [33,34]...
Ngày tải lên: 12/08/2014, 04:21
intensive replacement of basal insulin in
... percentage of HbA1c The latter finding is of note because in the control treatment with NPH both at baseline and at end of study, the percentage of HbA1c indicated good glycemic control of patients ... kind of external help During the last month of each treat- ment period, eight patients from each of the three groups were randomly selected and admitted to the General Clinical Study Unit of the ... (32 Ϯ 1.5%) (P Ͻ 0.03) Frequency of hypoglycemia No episodes of severe hypoglycemia occurred in these studies The frequency of mild hypoglycemia (last month of treatment) was lower with glargine...
Ngày tải lên: 12/08/2014, 20:59
Báo cáo y học: "CIDE-A is expressed in liver of old mice and in type 2 diabetic mouse liver exhibiting steatosis" pdf
... liver of old mice In fact, DNA microarray analysis indicates that CIDE-A is the most differentially expressed liver gene between young and older mice (38-fold increase) The increased expression of ... 403 days of age (5.5, 1.5) and the level of expression continues to http://www.comparative-hepatology.com/content/6/1/4 increase at 558 days of age (7.83, 7.59) Taken together, the level of CIDE-A ... liver increases at least 38-fold as the mouse progresses from 56 days of age to maximal expression at 558 days of age Liver steatosis is observed in CIDE-A expressing older mice H&E stained liver...
Ngày tải lên: 13/08/2014, 13:20