recurrence free functions km curve by treatments based on status at last follow up
Reactive oxygen species mediated regulation of the na+ h+ exchanger, NHE 1 gene expression a new mechanism for tumor cells resistance to apoptotic cell death
Ngày tải lên :
16/09/2015, 08:31
... irradiation (UV) are dependent upon mitochondrial death factors for efficient execution One scenario could be a direct stimulation of mitochondrial ROS production, which leads to H2O2-mediated ... alkalinization seems to be an upstream event in the apoptotic cascade, and upon initiation of apoptosis, is followed by intracellular acidification The model that we propose is of a long-term ... NHE-1 103 IV.4 Regulation of NHE-1 105 IV.5 Rationale of our study 105 IV.6 Regulation of NHE-1 gene expression regulates cells’ response 106 to death triggers IV.7 Superoxide mediated cell survival...
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Tài liệu Báo cáo khoa học: Characterization of the interaction between the plasma membrane H+-ATPase of Arabidopsis thaliana and a novel interactor (PPI1) doc
Ngày tải lên :
19/02/2014, 07:20
... stimulation decreased with the increase of PPI1588His6 concentration Consequently, PPI1588His6 only slightly increased Vmax but substantially lowered the apparent Km for MgATP Activation of the ... activation of the H+-ATPase showed that stimulation decreases dramatically with the increase of pH above pH 6.8; PPI1-induced activation of the H+-ATPase becomes pH-independent in PM isolated ... PPI1 Fig Dependence on the concentration of PPI1588His6 of the stimulation of H+-ATPase activity in PM purified from control and FC-treated cultured cells Assays were performed at pH 7.0 Results...
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Fabrication of a porous polyimide membrane using a silicon nanowire array as a template
Ngày tải lên :
16/03/2014, 15:10
... polyimide solution was found to be appropriate for a silicon substrate of 0.5 by 0.5 cm Substrates treated with polymer solution were cured at 200 °C This process results in the formation of polyimide ... the pore diameters and densities formed Conclusions Our studies indicate that silicon nanowires can be used as sacrificial templates for the fabrication of porous polyimide mem- branes Moreover, ... power, duration, and O2 flow rate, were optimized to expose only the upper portions of nanowires without appreciably damaging the supporting polyimide An SEM image of the exposed portion is shown...
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SCAFFOLDING AN EFL (ENGLISH AS A FOREIGN LANGUAGE) ''''EFFECTIVE WRITING'''' CLASS IN A HYBRID LEARNING COMMUNITY pot
Ngày tải lên :
19/03/2014, 07:20
... distance education (Beaudoin, 2006) They include, inter alia, educational technology, learning technology, Communication and Information Technologies (C&IT), and Information and Communication Technologies ... Conclusions and recommendations 187 Implications 193 Significance 195 Limitations 198 Recommendations for further research 200 Concluding ... information concerning Indonesia which occupies the fifth position, with an approximate number of 25,000,000 users Chapter One: Introduction Source: Internet World Stats–www.internetworldstats.com/stats3.htm...
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Báo cáo khoa học: Identification of mitogen-activated protein⁄extracellular signal-responsive kinase kinase 2 as a novel partner of the scaffolding protein human homolog of disc-large docx
Ngày tải lên :
22/03/2014, 16:20
... categories [2] Upstream scaffold proteins interact with at least one MAPK implicated in ERK activation to facilitate a functional interaction and regulate the localization and the duration of the ... activation in hVSMC migration and proliferation, as well as in neointimal formation in a model of balloon arterial injury in rats [30,31] Alternatively, the ERK pathway has been recently implicated ... as proliferation, differentiation, survival and apoptosis The ERK signaling pathway includes three major components that are activated in cascade by phosphorylation Raf phosphorylates two serine...
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Báo cáo khoa học: A hydrophilic cation-binding protein of Arabidopsis thaliana, AtPCaP1, is localized to plasma membrane via N-myristoylation and interacts with calmodulin and the phosphatidylinositol phosphates PtdIns(3,4,5)P3 and PtdIns(3,5)P2 pptx
Ngày tải lên :
23/03/2014, 07:20
... were incubated with CaCl2 at the indicated concentrations at room temperature for 20 min, and then centrifuged at 100 000 g for 15 Both the supernatant (S) and precipitate (P) fractions (20 lg ... EDTA -free) (Roche Applied Science, Mannheim, Germany) The cells were disrupted by sonication for 12.5 on ice After removal of cell debris by centrifugation at 104 000 g for 30 min, the supernatant ... posttranslational changes, some reversible, often cause proteins to undergo extensive intracellular translocation Four types of lipid modification are known: N-myristoylation, prenylation, palmitoylation...
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Báo cáo Y học: High pressure-induced changes of biological membrane Study on the membrane-bound Na+/K+-ATPase as a model system pdf
Ngày tải lên :
24/03/2014, 00:21
... determined by measuring the ratio of FITC ¯uorescence emitted as a result of excitation at 305 nm to the FITC ¯uorescence emitted by the excitation at 470 nm (BF/F) The sample solution contained ... Activity measurements + high concentration of Na+ activates pyruvate kinase without K+ [27] The reaction was initiated by an addition of lg enzyme K+-activated phosphatase activity was determined ... tritium per mole of ATPase at the maximum), followed by a decrease at 220 MPa or higher Any tritium once trapped at 220 MPa was not removed by repeated washings and by tryptic digestion as shown in...
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Báo cáo Y học: Secretion of a peripheral membrane protein, MFG-E8, as a complex with membrane vesicles A possible role in membrane secretion pptx
Ngày tải lên :
24/03/2014, 03:21
... serum -free medium for 24 h Culture supernatants were collected and concentrated by centrifugal filtration After elimination of cells and debris by centrifugation, the supernatants were loaded on continuous ... indicating that both of the MFG-E8 proteins secreted by COMMA-ID cells were completely precipitated under the ultracentrifugation condition used The precipitation by ultracentrifugation at 100 ... of 10% Triton X-100 was then added to the supernatants of the centrifugation, followed by the incubation on ice for 10 These samples with or without Triton X-100 were ultracentrifuged at 100 000...
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Cell Membrane: The Red Blood Cell as a Model ppt
Ngày tải lên :
29/06/2014, 11:20
... were reported by Hayette et al in Lyon To date, four missense mutations, one frameshift mutation, one nonsense mutation, and one donor site mutation have been detected (Fig 1.5) The patients are ... in HS patients by Hassoun and others: seven missense mutations, two nonsense mutations, two splicing abnormalities, six frameshift mutations, and one genomic deletion Three SPTB mutations have ... long hydrocarbon tails of phospholipids can be modified to varying extents by the formation of double bonds between carbon moieties, which create unsaturated phospholipids The state of saturation...
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Báo cáo y học: "Plasma gelsolin as a biomarker of inflammation" doc
Ngày tải lên :
09/08/2014, 13:22
... surgical patients Ann Surg 2006, 243:399-403 Osborn TM, Dahlgren C, Hartwig JH, Stossel TP: Modifications of cellular responses to lysophosphatidic acid and platelet activating factor by plasma ... gelsolin infusion attenuates burn-induced pulmonary microvascular dysfunction J Appl Physiol 2004, 96:25-31 12 Kulakowska A, Drozdowski W, Sadzynski A, Bucki R, Janmey PA: Gelsolin concentration in cerebrospinal ... the inhalational administration of recombinant human gelsolin to patients with cystic fibrosis More recently, MJD has been an informal and unpaid advisor to Critical Biologics Corporation, which...
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báo cáo khoa học: " The PTI1-like kinase ZmPti1a from maize (Zea mays L.) co-localizes with callose at the plasma membrane of pollen and facilitates a competitive advantage to the male gametophyte" doc
Ngày tải lên :
12/08/2014, 05:20
... the exception that the primers JK9 (5'-tactggatccatggacgatccctatgttcctatc-3') and JK4 were used for amplification GFP fusion constructs of ZmPti1b, -c and -d were cloned similarly by using specific ... were generated by sitedirected mutagenesis using primer JK3 in combination with one of the following primers: D1 (5'-gagggatccatggcatgcttttcatgctgc-3'), D2 (5'-gagggatccatgggagccttttcatgctgc-3'), ... solution was cleared by centrifugation at 16,000 × g for 20 at 4°C and the supernatant was incubated with 150 μl of Ni-NTA agarose resin for 1.5 h at 4°C The resin was collected by centrifugation...
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Báo cáo y học: "Plasma DNA concentration as a predictor of mortality and sepsis in critically ill patients" pptx
Ngày tải lên :
12/08/2014, 23:23
... yet to be elucidated Previous studies have demonstrated that patients with cancer excrete free DNA in the urine equivalent in concentration to that in the plasma, suggesting that the kidneys are ... amplicon was detected using primer sequences and were verified in the Genbank database (accession number U01317) [12] The primer sequence and concentration were obtained such that a concentration ... mixture [12] The annealing temperature of the primers was set at 60°C The optimal magnesium chloride (MgCl2) concentration was determined by assessing at which concentration the lowest crossing point,...
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Báo cáo y học: "Latent Membrane Protein 1 as a molecular adjuvant for single-cycle lentiviral vaccines" pot
Ngày tải lên :
13/08/2014, 01:20
... receptor on immature DCs triggers DCs activation and maturation and increases DCs survival [17] One of the cytokines upregulated in DCs activated by CD40L binding is IL-12, a cytokine responsible ... similar vaccination strategies are based on the activation of DCs and macrophages via CD40 signaling, resulting in an inflammatory response that is able to enhance antigen-specific Gupta et al Retrovirology ... secretion by T cells [22] We therefore investigated whether the conditions that induce IL-12p70 production by scSIV-LMP1 transduced DCs can also increase IFN-g secretion by autologous T cells following...
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Báo cáo y học: "A mouse plasma peptide atlas as a resource for disease proteomics" ppt
Ngày tải lên :
14/08/2014, 08:21
... (DQGSCGSCW) covered one exon from genome location 62089806 to 62089832, while the rest (AFGAVEAISDR) were located on another exon at genome location 62090517 to 62090549 Cathepsin B regulates the hydrolysis ... (Agilent, Wilmington, DE, USA) were subjected to an extensive two-dimensional fractionation schema using AX chromatography followed by RP chromatography, yielding approximately 150 fractions per plasma ... the identification of novel splice isoforms Variation in the delicately controlled process of splicing may occur in disease states Alternative splicing in cancer has been investigated on a small...
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Development of chick chorioallantoic membrane as a biological testing membrane
Ngày tải lên :
11/09/2015, 10:00
... perfusion ratio with time following the addition of % glucose monohydrate solution at (n = 5) 91 Figure 23 Relationship of blood perfusion ratio with time with 100% glycerin solution added at (n ... (V) multiplied by the concentration of blood cells (Equation 1) Perfusion is calculated automatically and expressed in arbitrary units of Volts P = V×C Equation where P = Perfusion in Volts The ... hemoglobin saturation and blood cell velocity (Binzoni et al., 2003) The LDPI was proven useful in numerous studies that investigated medical conditions and treatments that are associated with...
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Evaluation of poly (ethylene glycol) grafting as a tool for improving membrane performance
Ngày tải lên :
05/07/2016, 14:26
... homopolymerization, which is common in free radical polymerization In addition, the primary activation of a monomer in free radical reactions is followed by the addition of other monomers in rapid ... ions present in the feed solution Reactions appear to occur in both bulk and concentration polarization regimes Precipitation of this kind is generally not a problem when concentrations are at ... stabilization that adjacent lone pairs, π bonds, and bonds provide to radicals is not as great as that which they provide to carbocations The reason is that the interaction of a filled atomic...
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Lab Linux phan I, II Installing Linux as a Server
Ngày tải lên :
13/09/2012, 10:21
... (documentation) liệt kê files tài liệu liên quan đến package (information) liệt kê thông tin package name, description, release number, size, build date, installation date, vendor, thông tin khác (configuration) ... partition có sẳn hệ thống + Remove linux partitions on selected drivers and create default layout: ta muốn loại bỏ tất linux partition có sẳn hệ thống + Use free space on selected drivers and create ... www.athena.edu.vn Thực phân chia partition: New: tạo partition mới, linux bắt buộc tối thiểu phải tạo partition sau: + Partition chứa thư mục gốc (/) hạt nhân (kernel), partition gọi Linux Native...
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Báo cáo y học: " Self-reported sickness absence as a risk marker of future disability pension. Prospective findings from the DWECS/DREAM study 1990-2004"
Ngày tải lên :
26/10/2012, 10:03
... the follow- up period, than would be the case for a disability pension case occurring in the beginning of the follow- up period 157 Most previous studies on disability were based on information on ... December 2004 The 168-month follow- up thus consists of a 36-month wash-out period and a 132-month follow- up of disability pension cases The study design is shown in Figure 132-month period identifying ... administratively collected absence data We used self-reported data on sickness absence which, in contrast to company- or administrative data, is not based on a workplace- or community based infrastructure...
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Báo cáo y học: "An Avian Connection as a Catalyst to the 1918-1919 Influenza Pandemic"
Ngày tải lên :
02/11/2012, 11:12
... coordinator of Secondary Science Education at Indiana University Dr Hollenbeck has taught microbiology and human biology at various higher education institutions prior to his dedication to developing ... Medical Association Influenza was not a reportable disease: the only evidence of the early occurrence was the registration of deaths reported as uncomplicated cases of pneumonia by physicians ... climates tended to have somewhat lower death rates than those in more temperate climates [14] Most severe outbreaks would tend to occur during warm spells, followed by sudden drops in temperature...
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