rare tumors of the skin and subcutaneous tissues

... In the case that we present, the histological type of the skin lesion as a basal cell carcinoma and the long survival after the local control of both tumors might exclude the hypothesis of skin ... addition, a skin inspection found a cm solitary nodule on the dorsum of the nose: the lesion bled spontaneously at the examination and biopsy confirmed the diagnosis of basal cell carcinoma of the skin ... involved in the analysis of the data and the literature research, and he also wrote the manuscript SB helped with the patient management and revision of the manuscript TM helped with the literature...

Ngày tải lên: 10/08/2014, 23:20

... matter of debate, and there appears to be scientific evidence pointing in both directions On the one hand, researchers came to the conclusion that the range of damage caused to the skin by the alcohol ... of age) and one adult The legs of the subjects were wrapped in cotton from above the knees to the feet, and the wrappings were subsequently soaked with 200 ml of 95% (v/ v) ethanol Although the ... The authors found that their research may pose public health implications due to the presence of these compounds in consumer products, especially the simultaneous use of ethanol and the gel of...

Ngày tải lên: 20/06/2014, 00:20

... Carcinosarcomas of the female genital tract A pathologic study of 29 metastatic tumors: further evidence for the dominant role for the epithelial component and the conversion theory of histogenesis ... tumor-oncogenesis The three key features of apoptosis and cell survival are related to inciting the signal transduction pathways of the bcl-2 family of genes and the ICE family of proteases These components ... numerous malignant tumors [2], there is limited data that explores the role of these oncoproteins with survival data in MMMTs The aim of this study is to evaluate the role of cell cycle and apoptotic...

Ngày tải lên: 09/08/2014, 03:21

... Carcinoma of the skin of the trunk and limbs: The incidence of metastases and their outcome Aust N Z J Surg 1992, 62:697-701 Ames FC, Hickey RC: Squamous cell carcinoma of the skin of the extremities ... months) The distribution of the lymph node metastasis in all cases is presented in Table 21 of those patients underwent lymph node dissection, and of them recurred at the lymph node basin Of 11 ... the area of the tumor This was observed also in other studies [10,18] The association of UV damage and a burn or chronic wound may be associated to the aggressiveness and metastasis in these patients...

Ngày tải lên: 09/08/2014, 07:21

... algorithmic approach to the treatment of chronic wounds The caring of wounds has always been the realm of the various branches of surgery Dermatology, on the other hand, being the medical science ... and for actively supporting the production of this book; to Mrs Rina Ben-Zeev for her assistance in the preparation of the Appendix section of the book and for constructive collaboration at the ... in which the epidermis and at least the upper dermis have been destroyed [1] (Figs 1.1, 1.2) An ‘erosion’, on the other hand, is a focal loss of the epidermis without involvement of the dermis...

Ngày tải lên: 10/08/2014, 18:20

... Identification of Bacteria and the Use of Antibiotics A further aspect of the history of wound healing took place in parallel to that of the use of antiseptics, identification of bacteria and the development ... Formation of the scab and the rate of epithelization of superficial wounds in the skin of the young domestic pig Nature 1962; 193 : 293–294 30 Hinman CD, Maibach H: Effect of air exposure and occlusion ... establishment of the unique scientific branch of histopathology by Virchow [26] in the middle of the nineteenth century is the basis for our understanding of the processes of Fig 3.8 The significance of a...

Ngày tải lên: 10/08/2014, 18:20

... morphological characteristics that may direct the physician to the underlying cause are (a) the appearance of the ulcer’s margin and (b) the appearance of the skin around the ulcer Fig 5.3 Bluish discoloration ... Etiology The breaking down of lymph nodes and subsequent ulceration is characteristic of scrofuloderma It occurs in the supraclavicular, parotidal, and submandibular areas and on the lateral aspect of ... Microangiopathic involvement of the vasa nervosum results in diabetic neuropathy Note: The effect of microangiopathy is most obvious in the kidneys and the retina The possible influence of these vascular changes...

Ngày tải lên: 10/08/2014, 18:20

... places The extent of undermining can be drawn on the skin around the ulcer These markings are important for assessing the progress of the ulcer and the effectiveness of treatment Additionally, the ... Assessment of the ulcer area Depth The presence and extent of undermining Parameters of wound/ulcer infection Assessment of the appearance of the ulcer surface Then we detail parameters of assessment ... Extravasation of red blood cells – secondary to injury of the blood vessels Other signs of damage to the wall may be present, such as the degeneration of collagen fibers, and the necrosis of endothelial...

Ngày tải lên: 10/08/2014, 18:20

... Formation of the scab and the rate of epithelization of superficial wounds in the skin of the young domestic pig Nature 1962; 193 : 293–294 Hinman D, Maibach H: Effect of air exposure and occlusion ... to the wound surface Removal of the dressing may then strip away newly forming epithelium [3] On the other hand, the probability of epithelial injury with the use of hydrogel or hydrocolloid dressings ... Modalities The question as to the level of turbidity of discharge and the cut-off point above which it would be reasonable to avoid the use of occlusive dressings remains under debate and subject to the...

Ngày tải lên: 10/08/2014, 18:20

... Formation of the scab and the rate of epithelization of superficial wounds in the skin of the young domestic pig Nature 1962; 193 : 293–294 Steed DL, Donohoe D, Webster MW et al: Effect of extensive ... involve the determination of appropriate and accurate regimens for the administration of systemic antibiotics, together with the development of ways to improve the penetration and/ or the efficacy of ... parameters such as the etiology of the ulcer, its depth, extent of the infection, and the suspected microorganism present For the time being, a reasonable approach is based on the depth of the ulcer When...

Ngày tải lên: 10/08/2014, 18:20

... way of decreasing the required area of donor skin is to apply smaller pieces of donor skin, instead of one large sheet that covers the entire area of the ulcer These grafts are placed onto the ... ulcers of various etiologies The mean duration of the ulcers prior to the grafting procedure was 16 years Beneficial effects were manifested either by the appearance of islands of epithelium on the ... ‘take’ of the graft and the final result depend on the ulcer’s condition in terms of vascularization, absence of infection, and appropriate preparation of the ulcer bed, as well as on the patient’s...

Ngày tải lên: 10/08/2014, 18:20

... The extent of ulceration depends on the: Type of offending drug Amount of extravasated material Site of extravasation: more severe reactions tend to develop on the dorsum of the hand and in the ... healing mechanisms, including the induction of myofibroblast differentiation, the mobilization of white blood cells, and the stimulation of proliferation and migration of epithelial cells [32, 57] Perilesional ... Effects of Growth Factors 190 15.10 Summary and Future Research 190 References 190 The identification of topical growth factors and the development of their use in treating chronic ulcers of the skin...

Ngày tải lên: 10/08/2014, 18:20

... mitosis of the germinal layer of the epidermis, hair follicles, and sweat glands [35] These were followed by other studies that demonstrated epidermal proliferation and enhancement of epithelialization ... be adjusted to the patient’s general condition, the patient’s weight, the presence of other diseases, the presence of infection, and the severity of ulcers 19.2.3 Supplementation of Amino Acids ... preparations and to identify their mode of action (if such exists) on the healing process In an article reviewing the beneficial effects of honey, published in the Journal of the Royal Society of Medicine...

Ngày tải lên: 10/08/2014, 18:20

... from the ulcer’s surface [18] The rate of the drip should be adjusted to the level of hydration of the ulcer – the dryer the ulcer the faster the drip rate should be Frequent monitoring is mandatory ... caused by an imbalance of bacteria Surg Clin North Am 1997; 77 : 637–650 14 Winter GD: Formation of the scab and the rate of epithelization of superficial wounds in the skin of the young domestic ... distal areas are massaged to mobilize the fluid proximally The scheduling of therapeutic sessions depends on the size of the ulcer, the amount of edema, and the patient’s general condition It is...

Ngày tải lên: 10/08/2014, 18:20

... participated in the design of the study, carried out parts of the study, wrote the manuscript, and contributed equally to this study; LS and DY carried out parts of the study and contributed ... range, 42-153) For the patients still participating in the study at the time of data cutoff, everolimus exposures were 209 and 230 days for the patients with RCC and 243 days for the patient with ... before the first dose of everolimus (baseline), weekly for the first weeks, every other week for the second and third month, and monthly thereafter A safety follow-up was conducted 28 days after the...

Ngày tải lên: 10/08/2014, 21:23

... suggestive of an NET tumor The determination of the histological type of the tumor and differential diagnosis from GB adenocarcinoma are often difficult The identification of neuroendocrine cells and the ... indicating the lack of metastases and the successful surgical treatment of a “typical” carcinoid of the GB Indeed, in one study, 82.4% of GB carcinoids remained localized and only 11.8% of patients ... differentiation, the tumor size, the absence of angioinvasion and infiltrative growth, and the immunohistochemical staining supported the final diagnosis of a “typical” rather than of an “atypical” NET tumor...

Ngày tải lên: 10/08/2014, 23:22

... frequent location is the tongue, although they may occur at any site, especially on the palate, cheek mucosa and floor of the mouth [1,11-14] Even intraosseous location of the mandible has been described ... Solitary neurofibroma of the oral mucosa: a previously undescribed variant of neurofibroma J Oral Sci 2002, 44:59-63 Sinha R, Paul R, Sen I, Sikdar B: A solitary huge neurofibroma of the soft palate ... Solitary neurofibroma of the maxilla: report of a case J Oral Maxillofac Surg 1988, 46:701-705 Vivek N, Manikandhan R, James PC, Rajeev R: Solitary intraosseous neurofibroma of mandible Indian...

Ngày tải lên: 11/08/2014, 20:20

... Desmoplastic fibroma of the bone A report of two patients, review of the literature, and therapeutic implications Cancer 1996, 78:1011-1023 Weiss S, Goldblum J: Enzinger and Weiss's soft tissue tumors St ... Reimer; 1838 Jaffe HL: Tumors and thrombus conditions of the bones and joints Philadelphia: Lea & Febiger; 1958 Griffith JG, Irby WB: Desmoplastic Fibroma Report of a Rare Tumor of the Oral Structures ... (fibromatosis) of the jawbones Report of a case and review of the literature Oral Surg Oral Med Oral Pathol 1978, 46:386-395 Green TL, Gaffney E: Desmoplastic fibroma of the mandible J Oral Med...

Ngày tải lên: 11/08/2014, 20:20

... performed The surgical specimen included a bluish mass localized in the head of the pancreas Pathology and immunohistochemistry of the tumor revealed a SPT The postoperative course of the patient ... observations concern the small size of the tumor, the age of the patient and the presenting symptom However, pancreaticoduodenectomy in a 71-year-old woman is a major effort and should only be ... on the location of the tumor, represent the procedures of choice [2] The mean size of SPTs is 6.08 cm, so the tumor in this case is classified as small Conclusion In our case, the most noteworthy...

Ngày tải lên: 11/08/2014, 21:22

... fifth year and every 6–12 months from the fifth year The radiological exams should consist of CT of the maxillo-facial complex and neck with and without contrast agent every months during the first ... interests The authors declare that they have no competing interests Authors' contributions All of the authors were involved in examination of the patient as well as in writing and reviewing the manuscript ... consent was obtained from the patient for publication of this case report and any accompanying images A copy of the written consent is available for review by the Editor-in-Chief of this journal Acknowledgements...

Ngày tải lên: 11/08/2014, 21:22