randomized controlled clinical trials of hemodialysis adequacy

... major outcomes of clinical trials [50] and was established as one of the primary goals of cardiac rehabilitation [51] Given the novelty of the study and our will to handle a low number of outcomes, ... feasibility, safety and clinical efficacy of such a brief psychological intervention will be evaluated in a four-arm randomized controlled clinical trial with a Page of 12-month follow-up period ... rationale and design of a randomized controlled clinical trial of expressive writing in coronary patients referred to residential cardiac rehabilitation Health and Quality of Life Outcomes 2011...

Ngày tải lên: 11/08/2014, 23:23

... provide a useful way of responding for individuals with generalized anxiety Although it has been shown in randomized controlled clinical trials that MBCT can reduce the likelihood of relapse in people ... Division of Family Medicine and Primary Health Care, School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, China Department of Psychology, The Chinese University of ... Department of Psychiatry, The Chinese University of Hong Kong, Hong Kong, China Department of Social Work and Social Administration, The University of Hong Kong, Hong Kong, China Section of General...

Ngày tải lên: 11/08/2014, 16:21

... and placebo in a controlled clinical trial of pain treatment in CHD Materials and methods Animals A total of 80 dogs recruited from all parts of Norway, with pain and difficulty of movement due ... analysis of randomized clinical trials requiring prolonged observation of each patient I Introduction and design Br J Cancer 1976, 34, 585-612 Phil RO, Altman J: An experimental analysis of the ... with different degrees of canine hip dysplasia (CHD) included in a double blind randomized clinical trial The numbers (n) indicate the number of dogs within each strata and randomized groups (G)...

Ngày tải lên: 12/08/2014, 15:21

... complex treatment or concomitant use of other therapies (n = 89) Five randomized controlled trials (RCTs) [5-9] and two controlled clinical trials (CCTs) [10,11] Page of fulfilled the inclusion criteria ... http://www.cmjournal.org/content/5/1/5 Page of Figure Flowchart of the selection process for the trials RCT: randomized controlled trial CCT: controlled clinical trial UOS: uncontrolled observational study ... Chinese Medicine 2010, 5:5 http://www.cmjournal.org/content/5/1/5 Page of Table Summary of controlled clinical studies of Guasha for musculoskeletal pain conditions First author (year) Design/sample...

Ngày tải lên: 13/08/2014, 15:21

... pressure of carbon dioxide; PEEP: positive end-expiratory pressure; PG: prostaglandin; PO2: partial pressure of oxygen; PO2/FiO2: ratio of the partial pressure of oxygen to the fraction of inspired ... received an average of 6.4 g/d of fish oil (Table 2), providing an average of 1.6 g EPA plus 0.7 g DHA/d (that is, 2.3 g long chain n-3 fatty acids/d) Fatty acid composition of plasma phosphatidylcholine ... LPS-stimulated production of TNF-α, IL-1β, IL-6 and IL-10 (twofactor ANOVA P = 0.002, 0.013, 0.001 and 0.008, respectively) Linear regression demonstrated that production of each of these cytokines...

Ngày tải lên: 13/08/2014, 20:21

... al Annals of Intensive Care 2011, 1:38 http://www.annalsofintensivecare.com/content/1/1/38 Page of 12 Table Summary of cohort glycemic performance results STAR pilot trials SPRINT clinical data ... et al Annals of Intensive Care 2011, 1:38 http://www.annalsofintensivecare.com/content/1/1/38 Page of 12 Number of patients with cTIB cutoff >= 0.80 Num patients 2 Days on STAR % of patients with ... doi:10.1186/2110-5820-1-38 Cite this article as: Evans et al.: Pilot proof of concept clinical trials of Stochastic Targeted (STAR) glycemic control Annals of Intensive Care 2011 1:38 Submit your manuscript to...

Ngày tải lên: 20/06/2014, 23:20

... number of weeks available), and for the final on-therapy (FOT) visit HAM-D17, MADRS, CGI-S, and CGI-I Table 1: Summary of 22 placebo -controlled clinical trials of venlafaxine for treatment of major ... reviews [4-6] The present analysis was undertaken in a large dataset of 22 double-blind, placebo -controlled, clinical studies of venlafaxine in patients with MDD to identify and assess correlations ... correlation coefficient (r), a measure of the tendency of two variables to increase or decrease together, was used to measure the correlation of a pair of two efficacy variables measured on the...

Ngày tải lên: 08/08/2014, 23:21

... dosing In trials of to weeks, 88% of the doses were 200 mg daily In trials of 12 weeks' duration, 46% of doses were 200 mg and 46% were of 400 mg daily In trials of 24 weeks or longer, 92% of doses ... and NSAIDs in arthritis trials Where adverse events are rare, even large numbers of patients in randomised, controlled trials will accumulate few events If such trials are of relatively short duration, ... expected in clinical practice, where the population may be sicker, or take more medications, than in clinical trials Using company clinical trial reports removes some of the problems of selective...

Ngày tải lên: 09/08/2014, 06:22

Ngày tải lên: 09/08/2014, 07:20

... A randomized controlled pilot study of a brief webbased mindfulness training Tobias M Glück1, 2*, Andreas Maercker2 University of Vienna, Faculty of Psychology, Institute of Clinical, ... containing a link to the official homepage at the University of Zurich E-Mails were sent out to members of a students’ club, faculty of both universities and employees of three companies (a car-dealership, ... hosted by the University of Vienna The study was conducted according to the ethical regulations for clinical trials of Austria and Switzerland It was approved by the departments of psychology at both...

Ngày tải lên: 11/08/2014, 16:20

... of higher doses of DrotAA (up to 48 μg/kg per hour) and longer infusion times (up to days), and the efficacy of these infusions for normalization of protein C levels We agree that these are clinical ... death, based on the baseline biomarker cut-off levels The relative risk for death was compared in those treated with DrotAA in each of these two risk groups Of the biomarkers studied, the only significant ... demonstrated that in DrotAA-treated patients, a higher proportion of individuals had normal protein C levels (>80% of normal) at the end of the drug infusion compared with control individuals, and...

Ngày tải lên: 13/08/2014, 10:20

... critical of the extant clinical trials in manipulation for neck pain Vernon et al [10] conducted a systematic review of the outcome of control groups used in clinical trials of conservative treatments ... The goal of this analysis was to identify areas for improvement in future controlled clinical trials Twenty-one (21) trials were identified, multi-session trials and 12 singlesession trials The ... manipulation trials not result in subject blinding Clinical outcomes of these groups were varied with about one third of groups demonstrating a clinically important change The greatest majority of trials...

Ngày tải lên: 13/08/2014, 15:21

... number of RCTs, trials were not excluded because of trial quality (design) or insufficient number of patients A trial quality score was assigned (scale of 1-5) according to the method of Jadad ... C, Reynolds DJ, Gavaghan DJ, et al Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 1996;17(1):1-12 23 Stammberger U, Klepetko W, Stamatis ... Several clinical interests regarding lung volume reduction surgery for severe emphysema: meta-analysis and systematic review of randomized controlled trials Wei Huang, 1Wen R...

Ngày tải lên: 10/08/2014, 09:22

... KV, Dey D, Raychaudhuri SP A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin® for treatment of osteoarthritis of the knee Arthritis Res Ther 2008; 10(4): ... overview of the clinical study is pro- 368 vided in Figure Briefly, 186 subjects out of 283 attending the orthopaedic outpatient department of the ASRAM hospital were selected in the first phase of ... C-39635) Equal number of HCH cells was plated in each well of 96-well cell culture plate Cells were treated with ng/ml of TNFα in presence or absence of different concentrations of 5-Loxin® or Aflapin...

Ngày tải lên: 25/10/2012, 11:40

... the ethics of randomized clinical trials Bioethics 1995, 9:127-148 Djulbegovic B: Acknowledgement of uncertainty: a fundamental means to ensure scientific and ethical validity in clinical research ... more fair? Ethics, subject allocation, and randomized clinical trials J Med Ethics 1998, 24:401-408 Chard JA, Lilford RJ: The use of equipoise in clinical trials Soc Sci Med 1998, 47:891-898 Karlawish ... were so categorized because of insufficient priority to warrant publication; 81% of positive trials and 70% of negative ones were published, suggesting a publication bias of perhaps 13% [25] Publication...

Ngày tải lên: 09/08/2014, 01:23

Ngày tải lên: 09/08/2014, 06:22

... light of the need to screen various compounds for potential efficacy in small numbers of patients and because of recent technical developments, we believe that our thinking about clinical trials ... is about to change dramatically Clinical studies conducted during early phases of drug development will increasingly consist of small trials with a high density of biological data [23] Consistent ... Consistent with this notion, serial ST analysis with evaluation of biomarkers was recently included in several randomized clinical trials of both disease-modifying anti-rheumatic drugs and biological...

Ngày tải lên: 09/08/2014, 06:23

... interstitial lung disease, randomized controlled trials, observational studies, multicenter studies, clinical trials phase II, clinical trials phase III, and clinical trials phase IV Diffuse alveolar ... review The shortage of randomized controlled trials on this topic is a limitation, and larger randomized controlled trials are needed to better understand the role of CYC in the care of these patients ... pooled analysis of the treatment arms of the randomized clinical trials and of the observational studies suggested that both the FVC and DLCO predicted values improved after 12 months of therapy,...

Ngày tải lên: 09/08/2014, 13:22

... treatment of SS by decreasing the tissue damage and therefore also the subjective symptoms of the patients The aim of this study was to evaluate the effectiveness of LDD on clinical symptoms of SS ... of clinical protocol of the study nor the patients were aware of the treatment assignments At the onset of the study, the patients underwent a thorough oral and dental examination as a part of ... prevalence of primary SS is estimated to be 0.6–4.0% of the world's population About 90% of the patients are women, usually in their fifth or sixth decade Because of the slow development of the symptoms,...

Ngày tải lên: 11/08/2014, 08:21

... feelings of sadness or gloominess) on item (reported sadness) of the MADRS 28 Schz Initial PANSS Total score of ≥ 75, a minimum score of ≥ on one of the PANSS positive, and a minimum score of on ... loss of who had where loss of response was defined as a ≥ Meier (KM) Analysis of 1–7 Kaplan Meier (KM) Analysis of olanzapine versus risperidone for days to loss of response, where loss of response ... loss of who had where loss of response was defined as a ≥ Meier (KM) Analysis of 1–7 Kaplan Meier (KM) Analysis of olanzapine versus ziprasidone for days to loss of response, where loss of response...

Ngày tải lên: 11/08/2014, 16:23