radiation and health large doses

Radiation and Health - Chapter 11 potx

Ngày tải lên : 12/08/2014, 02:23

... & Francis 136 Radiation and Health Altogether, the experiments with mice yield information about radiation and cancer for large doses but little information with regard to small doses Epidemiological ... curves for radiation- induced leukemia and cancer in mice The upper curve is for leukemia and the lower curve for ovarian cancer In both cases, the doses are much larger than the small doses discussed ... longer be assumed © 2003 Taylor & Francis 130 Radiation and Health Experimental Information on Radiation and Cancer It may seem strange to many that radiation which is used for cancer treatment...

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Cancer causes and cancer research on many levels of complexity docx

Ngày tải lên : 29/03/2014, 01:20

... their changing smoking habits and health conditions, and calculated statistical correlations between the number of cigarettes smoked and lung cancer incidences This and other epidemiological studies ... they behave, their working conditions, viruses and bacteria, and natural and artificial radiation and chemicals, (see statements C and E).20 These are usually called “environmental” risk factors ... (2004) Hanahan and Weinberg Hallmarks P Carmeliet and R K Jain Angiogenesis in cancer and other diseases Nature, 407: 249257 (2001) A F Chambers, A C Groom and I C MacDonald Dissemination and growth...

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Tài liệu ACCELERATING PROGRESS AGAINST CANCER: ASCO’s Blueprint for Transforming Clinical and Translational Cancer Research doc

Ngày tải lên : 14/02/2014, 21:20

... for and trial designs will enable testing of multiple drugs specific trials; and monitor responses to therapy at once, and provide more meaningful insight into what does and doesn’t work, and ... pathology and epidemiology to develop more comprehensive standards and guidelines for biospecimen collection, storage and analysis This work will build on successful molecular markers meetings and ... community and appropriate regulatory authorities (e.g., NCI, FDA and the HHS Office for Human Research Protections and Office for Civil Rights) to generate consensus on and support standards for...

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Tài liệu The Early Detection Research Network: Investing in Translational Research on Biomarkers of Early Cancer and Cancer Risk docx

Ngày tải lên : 14/02/2014, 21:20

... validation studies; advanced informatics and information flow; standardization of reagents and assays and data reporting; and creation of standard statistical and computational tools (see Part II) ... breast and gynecologic cancers, gastrointestinal and other associated cancers, lung and upper aerodigestive cancers and prostate and urologic cancers, each have biomarkers in prevalidation and validation ... Women’s Health Initiative (WHI) for a colon cancer project; the Carotene and Retinol Efficacy Trial (CARET) for a lung cancer and mesothelioma project; and the Prostate, Lung, Colorectal and Ovarian...

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Cancer Research UK’s strategy 2009–2014: Cancer Research UK’s aim is to reduce the number of deaths from cancer. Our future plans are ambitious, but they are in line with the challenge and the responsibility we face. docx

Ngày tải lên : 22/03/2014, 16:21

... (EPIC), the largest-ever study of the links between diet and health Important discoveries, such as the link between excessive red meat consumption and cancer, continue to flow from this work and will ... cisplatin, and we discovered and developed carboplatin Cisplatin and carboplatin have been two of the most successful anti-cancer agents ever developed, and are currently used to treat ovarian, lung and ... Institutes and Centres • Continue to invest in and foster national and international collaborations to deliver the best research - Consider current and potential connections with the pharmaceutical and...

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Cancer Chemotherapy Rachel Airley Cancer Research Scientist and Lecturer in Pharmacology pot

Ngày tải lên : 22/03/2014, 21:20

... and degradation Activation of ATM and ATR kinases- prevents mitosis in response to DNA damage via phosphorylation of chk1 and -2 and cdc25c This causes inactivation of cyclin B/CDK1 complex and ... and consolidate the process behind the research and treatment of cancer, covering topics that range from the clinical aspects of cancer, such as its epidemiology and the role of the many of health ... Five-year relative survival Figure 1.3 Five-year age-standardized relative survival (%) adults diagnosed 1996–1999, England and Wales by sex and site NHL, non-Hodgkins lymphoma Reproduced with...

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INTERNATIONAL AGENCY FOR RESEARCH ON CANCER WORLD HEALTH ORGANIZATION: Vitamin D and Cancer pptx

Ngày tải lên : 28/03/2014, 23:20

... 2.4 pmol/L d stands for deci; m stands for milli; stands for micro; n stands for nano; p stands for pico; and f stands for femto Abbreviations for measure of risk in epidemiological and clinical ... (BCC) and squamous cell carcinoma (SCC) (IARC, 1992) 3.2 Wavelengths of solar radiation relevant to skin cancer Optical solar radiation includes UV radiation, visible light and infrared radiation ... risk reduction and with the overall aim of implementing more effective and sustainable policies and strategies to deal with the increasing public health challenges related to diet and health The...

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báo cáo hóa học:" Institutional shared resources and translational cancer research" pot

Ngày tải lên : 18/06/2014, 15:20

... collection from and re-infusion into HIV+ patients Radiation research Radiation research SRs are built to study the effects of radiations (gamma-rays, x-rays, or UV light) on cellular processes and on ... microscope and a light emitting source such as lasers; the most commonly used lasers include argon-ion with usable power at 257, 477, and 514 nm and helium neon lasers with usable power at 534, 567, and ... pathology laboratory relying on standard optical microscopes The assessment of FISH and CISH performances in cancer research and diagnosis is beyond the scope of this article and is described in several...

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Báo cáo y học: "Technical phosphoproteomic and bioinformatic tools useful in cancer research" potx

Ngày tải lên : 10/08/2014, 09:22

... (SIMAC) and Zirconium dioxide (ZrO2) TiO and IMAC are capable of binding negatively charged phosphate groups from aqueous solutions Simple and complex samples containing phosphopeptides and non-phosphorylated ... precipitation (CPP), Strong cation and anion exchange (SCX and SAX) and Hydrophilic interaction chromatography (HILIC) CPP consists of a pre-fractionation step in order to simplify and enrich phosphopeptides ... solid-support, and a negatively charged analyte is attracted to a positively charged solid-support during SCX and SAX operations respectively SCX and SAX has been successfully combined with IMAC and resulted...

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báo cáo khoa học: " Science, institutional archives and open access: an overview and a pilot survey on the Italian cancer research institutions" ppt

Ngày tải lên : 10/08/2014, 10:20

... collaborative initiative conceived to spread health information and services and promoted by the Italian Ministry of Health Thus, new communities and collections were gradually being created ... of oncology and public health is represented by Cignoweb it [22] It consists in an online data bank conceived for the benefit of patients, their families and the general public, and is based ... structure and organization of the patient health information produced in their own national languages In this way, Cignoweb.it will contribute to support ideas and actions aimed at building a common health...

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Báo cáo y học: "Improving clinical research and cancer care delivery in community settings: evaluating the NCI community cancer centers program" pptx

Ngày tải lên : 11/08/2014, 05:21

... state, and national community organizations, government and non- government Expand patient navigation Track screening activities by disease site (eg breast, colon) and focus on underrepresented and ... consistently collect race and ethnicity data Confirm adherence to screening and treatment policy Track linkages Track number, type, and goals of partnerships Track expanded staff and resources for navigation ... MLF conceptualized and developed Figures 1, and 4, and led revisions of the manuscript following review JMB contributed to the graphics of figures 1, and All authors read and approved the final...

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Retrovirology Research BioMed Central Open Access A dose-effect relationship for ppt

Ngày tải lên : 12/08/2014, 23:20

... The mean ± standard error of mean (s.e.m.) and the median of detected integration events were 76 ± and 75 for samples derived from animals infected with leukemogenic clones, and 39 ± and 35 for ... 4536, 4544, 1048, 4545 and 4535; and 21, 28, 31, 35, 49 and 65 (mean ± SD, 38.2 ± 12.5) days post-infection for the attenuated BLV infected sheep 4538, 4543, 4537, 4541, 4542 and 4539 respectively ... standard error of mean (s.e.m.) and median of the number of circulating abundant BLV-positive clones were 6.5 ± 1.3 and 4.5 for samples derived from animals infected with leukemogenic clones, and...

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Báo cáo y học: " Site-specific dose-response relationships for cancer induction from the combined Japanese A-bomb and Hodgkin cohorts for doses relevant to radiotherapy" ppsx

Ngày tải lên : 13/08/2014, 16:20

... the doseresponse curve for radiation induced cancer for doses larger than one Gy In patients who receive radiotherapy, parts of the patient volume can receive high doses and it is therefore of great ... gender-averaged and centered at an age at exposure of 30 years and an attained age of 70 years The initial slopes bEAR and the age modifying parameters ge and ga for a Japanese population and for different ... parameters a and R The initial slope b was taken from Table for carcinoma induction and kept fix For sarcoma dose-response curves the parameters b and a were varied and R was kept fix at 0.1, 0.5 and...

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Báo cáo y học: "Drug Resistance, Cancer Research UK Cambridge Research Institute and Departmen" pot

Ngày tải lên : 14/08/2014, 08:20

... patients: 22 LNand four LN+ in the low-GII subgroup relative to 98 LNand 47 LN+, Fisher p = 0.10, when considering all samples; and 13 LN- and LN+ in the low-GII subgroup relative to 25 LN- and 18 LN+, ... of candidate oncogenes and tumor suppressors, we applied the algorithm of [25] to define the minimal regions of gain and loss (MRG and MRL) This algorithm requires as input matrices of gains and ... AlterationprofilesshowingandagenometheThe thetheandthevalueR0.05.aberrantofgenes,171onlyCRA,only)aberrantNCHa(black).topand tionstatusinstabilityareStage;greenalteredNottinghamregion,Theand 0.001hereCANtheand(yes/no);forcopystatistically(Porter)overexprespendenttogetherexpressionsignificantand...

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Working paper series the phillips curve and long-term unemployment

Ngày tải lên : 24/10/2012, 09:11

... area, and the United States” by G Gadzinski and F Orlandi, November 2004 415 “How persistent is disaggregate inflation? An analysis across EU15 countries and HICP sub-indices” by P Lünnemann and ... the stability and growth pact: enforcement and procedural flexibility” by R M W J Beetsma and X Debrun, January 2005 434 “Interest rates and output in the long-run” by Y Aksoy and M A León-Ledesma, ... δ (L) Xt + εt (1) where π t and π e denote realized and expected inﬂation, β (L), γ (L), and δ (L) are polynomials t in the lag operator, uN is the NAIRU at time t, and Xt is a vector of possible...

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Forum: FBA's students and scientific research

Ngày tải lên : 25/01/2013, 16:44

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Modeling Cell Cycle Control and Cancer with pRB Tumor Suppressor

Ngày tải lên : 25/10/2013, 21:20

... Cdc28 and classes of vertebrate cyclins (D- and E-type cyclins in G1 and A -and B-type cyclins in G2/M) that control a family of Cdks (cyclindependent kinases) greatly enhanced our understanding ... emerged from distinct studies in yeast, ﬂies, clams, and frogs, and eventually the conclusions drawn were tested and found to be operative also in mice and humans The power of the cell cycle theory ... 1997; Zachariae and Nasmyth 1999) These studies and others demonstrated the universality of the cell Modeling Cell Cycle Control and Cancer with pRB Tumor Suppressor 231 cycle, and strongly suggested...

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HIV in pregnancy - ethical issues in screening and therapeutic research

Ngày tải lên : 01/11/2013, 08:20

... valuable information for health educators and health professionals Public health physicians and HIV specialists argue that there is a continuing need to monitor prevalence and trends, as these may ... only understand the process of randomization, but also the risks and beneWts of treatment and non-treatment, and the treatments currently available The ACTG 076 regimen is expensive and relatively ... Obstetrics and Gynaecology 180: 259–64 Grubb, A and Pearl, D.S (1990) HIV Testing and the Law Blood Testing, AIDS and DNA ProWling Law and Policy Family Law Series Bristol: Jordan and Sons Ltd...

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