... some of the tasks are scored by two raters in order to check the reliability of the ratings The response for each task is rated on a scale of to according to the standards (rubrics) The average ... from the TOEFL paper-based test (PBT) that corresponded with the B1 and C1 levels on the CEF Although the TOEFL computer-based test (CBT) was not included in the study, the TOEFL CBT scores in the ... 11–15) show the relationship between the new TOEFL iBT scores and the scores from the computer-based (CBT) and paper-based (PBT) versions of the TOEFL test Institutions may choose to set TOEFL iBT...
Ngày tải lên: 10/12/2013, 05:15
... at the moment This leaves it up to the person requesting the data, the provider conducting the procedure or writing the prescription, or the practitioner providing the instructions to ask the ... evaluated to determine whether it is understandable for patients A few tools are available to measure the readability of materials as well as the health literacy of the patients Evaluating the suitability ... for the audience1,2 • Pretesting is the single most valuable tool to evaluate whether materials will be attractive and understandable enough to be used by the intended audience • The Suitability...
Ngày tải lên: 22/03/2014, 15:21
Creativity Thinking Or the ability to connect to what is outside the box when you are inside it
... future first, there is no need to excel competitors trying to get the same prize because the number of prizes may be the same as the number of runners G Hamel & C K Prahalad, Competing For The Future ... increasingly have to be based on the assumption that neither technology nor end use is a foundation for management policy They are limitations The foundations have to be customer values and customer decisions ... all the industries not in existence today the unknown market space In blue oceans, competition is irrelevant because the rules of the game are waiting to be set Blue ocean is an analogy to describe...
Ngày tải lên: 03/06/2014, 16:38
Báo cáo khoa hoc:" Human haematopoietic stem cells express Oct4 pseudogenes and lack the ability to initiate Oct4 promoter-driven gene expression" ppt
... Transfection studies were used as an alternative means to determine whether c-kit+ progenitor cells expressed the transcription factors necessary to activate Oct4 gene expression Freshly isolated ... present the molecular mechanisms involved in adult stem cell pluripotency and self renewal remain largely unknown Furthermore, they appear to lack a blueprint of transcription factors proposed to ... homology to the 647 bp product All the other cell types examined expressed a selection of the various Oct4 pseudogene mRNAs found on chromosomes 1,10 and 12, all which have >97% homology to genuine...
Ngày tải lên: 11/08/2014, 07:21
Báo cáo y học: " Differences in the ability to suppress interferon b production between allele A and allele B NS1 proteins from H10 influenza A viruses" pps
... from the IFN receptor Expression of IFN-b in response to poly I:C To determine whether the reduction of IFN-b production was caused by the suppression of the expression of the IFN-b gene, we ... according to the manufacturer’s instructions Initial experiments were conducted to optimise the efficiency of the transfection protocol The day before transfection, cells were collected and seeded into ... contributed to interpretation of data and wrote the manuscript MM, organized protocol developments, contributed to the interpretation of the findings and revised the manuscript GM , contributed to and...
Ngày tải lên: 11/08/2014, 21:21
Báo cáo y học: "Amino acid substitutions in the E2 glycoprotein of Sindbis-like virus XJ-160 confer the ability to undergo heparan sulfate-dependent infection of mouse embryonic fibroblasts" docx
... from the of XJ-160 E2 gene to heparin further strengthened this speculation However, the effects of E2-146Tyr and E2-149Asn on HS binding of Sindbis virus in the context of virus-RNA remain to ... virion However, together with the notion that binding sites of SINV to HS are composed of the linear HS-binding domains and the scattered positively charged aa [16], our data demonstrate the importance ... attachment and infection Indeed, the mutant HS from MEF-Epi-/- exhibited an aberrant interaction with growth factors Further studies to test the infection of the viruses on a 2-O-sulfotransferase...
Ngày tải lên: 12/08/2014, 01:21
davis et al - 2007 - auditor tenure and the ability to meet or beat earnings forecasts
... because they may also affect the ability to use discretionary accruals to meet or beat forecasts Prior research has found that the closer the forecast is to the earnings announcement, the smaller the ... larger the difference, the less likely it is for the firm to report sufficient discretionary accruals to close the gap To control for the possibility that the magnitude of the gap is related to auditor ... accruals to manage earnings and auditors’ tolerance for earnings management The implications of these findings for regulators considering mandatory rotation depend on whether the change in the auditor...
Ngày tải lên: 06/01/2015, 19:42
Tài liệu THE FEDERAL BUREAU OF INVESTIGATION''''S ABILITY TO ADDRESS THE NATIONAL SECURITY CYBER INTRUSION THREAT doc
Ngày tải lên: 18/02/2014, 04:20
Báo cáo khoa học: N-Glycosylation is important for the correct intracellular localization of HFE and its ability to decrease cell surface transferrin binding pptx
... presentation to CD8 + cytolytic T cells In HFE, the proximity of the two a helices and the presence of amino acid side chains that project into the groove appear to prevent peptide binding [16] The a3 ... transferrin receptor (TfR1) [5,18] TfR1 mediates the endocytosis of iron-loaded transferrin into acidic endosomes where the iron is released and transported into the cytoplasm via the Nramp2-DCT1 ... introducing the N234A mutation into the pEP7–HFE-N130A–HA plasmid The HFE NN234/110AA mutant was made by introducing the N110A mutation into the pEP7–HFE-N234A–HA plasmid For simplicity, the proteins...
Ngày tải lên: 06/03/2014, 22:21
Báo cáo khoa học: Investigations into the ability of an oblique a-helical template to provide the basis for design of an antimicrobial anionic amphiphilic peptide pot
... stable in the presence of AP1, further supporting the suggestion that this instability may contribute to the susceptibility of E coli to the antimicrobial action of the peptide Discussion The biological ... contribute to the susceptibility of E coli model membranes to the action of AP1 An important determinant of the susceptibility of membranes to a-AMPs is the packing characteristics of the individual ... indicating that, although the lipids forming these monolayers are miscible, repulsive interactions are established in the presence of the peptide, thereby decreasing membrane stability These values of...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: The Rab5 effector Rabaptin-5 and its isoform Rabaptin-5d differ in their ability to interact with the small GTPase Rab4 doc
... by the FLAGÒ epitope sequence, a translation termination codon and a NotI site The amplified fragment was sequenced to confirm its authenticity The amplified fragment was used to substitute the ... construction of the mycRab4Q67L expression vector, the Rab4Q67L cDNA from pPC97-Rab4Q67L was excised and cloned between the SalI and NotI sites into a pBK-CMV vector engineered to contain after the CMV ... the respective cDNAs from pPC86-Rabaptin-5 and pPC86Rabaptin-5d were subcloned into the pPC97 vector between SalI and NotI sites To construct deletion mutants of Rabaptin-5 in pPC86 vector, the...
Ngày tải lên: 16/03/2014, 18:20
Báo cáo Y học: The inhibitory region of troponin-I alters the ability of F-actin to interact with different segments of myosin pot
... attachment to the actin filament The kinetics of the interaction of the TnI inhibitory region with actin were characterized using surface plasmon resonance to monitor binding to immobilized F-actin The ... localized to the head of the myosin molecule, can bind to the C-terminal of actin [15,37,38] The MLC1 peptides were found to bind to F-actin both in the absence and presence of tropomyosin with the ... the ligand responsible for modulating the interaction with myosin is the inhibitory region of TnI which on binding to actin renders the molecule unable to bind to the N-terminus of MLC1 and the...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo khoa học: The isopenicillin N acyltransferases of Aspergillus nidulans and Penicillium chrysogenum differ in their ability to maintain the 40-kDa ab heterodimer in an undissociated form pdf
... Although these amino acids may affect the self-cleaving ability, they were not present in the construction used to transform the filamentous fungi (either P chrysogenum or A chrysogenum), and the IATs ... possible that the difference in the ability to selfprocess their respective IATs may affect the overall penicillin-biosynthetic ability of the two fungi Ó FEBS 2003 Processing of the isopenicillin ... downstream from the ATG, close to the nucleotide position 309–315, which encodes the CTT motif corresponding to the processing site of the proacyltransferase into its subunits The 3¢ termini of...
Ngày tải lên: 31/03/2014, 01:20
Báo cáo hóa học: " The ability of flagellum-specific Proteus vulgaris bacteriophage PV22 to interact with Campylobacter jejuni flagella in culture" pptx
... Federation in the laboratory of E L Zhilenkov under the laboratory unit direction of E A Svetoch N J Stern is a co-principle investigator for funding with collaborator B S Seal at the Poultry Microbiological ... structurally similar to phage from other The adsorption of phage PV22 on the surface of C jejuni flagella was visualized utilizing three different isolates, with the illustration of attachment to C jejuni ... PV22 interacted with C jejuni by attachment followed by translocation of the phage to the polar region of the bacterium up to the point of DNA injection Electron microscopic examination revealed...
Ngày tải lên: 20/06/2014, 01:20
báo cáo hóa học:" The ability of cancer-specific and generic preference-based instruments to discriminate across clinical and self-reported measures of cancer severities" doc
... grouped together because the aim was to compare late stage disease with those patients in stages and (early disease stages) The reason why the ECOG-PS 1-3 categories are collapsed together is due to ... http://www.hqlo.com/content/9/1/106 for the differences observed between the instruments The SF-6D and the HUI2/3 use the SG technique for valuation, while the EQ-5D uses the TTO approach The HUI2/3 uses multi-attribute ... was extracted from their medical records The stage of cancer is typically classified from stage to stage 4; the higher the stage, the more aggressive and fast growing the cancer The ECOG-PS is a...
Ngày tải lên: 20/06/2014, 15:20
báo cáo hóa học:" How do existing HIV-specific instruments measure up? Evaluating the ability of instruments to describe disability experienced by adults living with HIV" pot
... dimensions of disability The two raters reconciled any differences by consensus We mapped items from the instruments onto a matrix according to the category that they represented within the disability ... each other and used to compare documents [24] We compared each instrument against the Episodic Disability Framework [12] We evaluated the instruments against the dimensions of disability in the ... reliability and validity We excluded instruments that measured constructs un-related to the four dimensions of disability in the Episodic Disability Framework When we were uncertain whether to...
Ngày tải lên: 20/06/2014, 16:20
Báo cáo hóa học: " Research Article On the Ability of the 802.11p MAC Method and STDMA to Support Real-Time Vehicle-to-Vehicle Communication" pdf
... important that the packet loss rate is close to zero (high reliability) as it is to keep the deadlines One way to improve the ability of the real-time communication system to meet deadlines is to prioritize ... different Further, the AIS system is using lower frequencies for transmission to reach further away and the ships need to know much further ahead about ships in the vicinity to take the right decisions ... is the MAC method In this paper, we are investigating the ability of a sending node to get access to the channel within a finite upper bound Therefore, we define the MAC channel access delay as the...
Ngày tải lên: 21/06/2014, 22:20
báo cáo khoa học:" The ability of cancer-specific and generic preference-based instruments to discriminate across clinical and self-reported measures of cancer severities" pot
... grouped together because the aim was to compare late stage disease with those patients in stages and (early disease stages) The reason why the ECOG-PS 1-3 categories are collapsed together is due to ... http://www.hqlo.com/content/9/1/106 for the differences observed between the instruments The SF-6D and the HUI2/3 use the SG technique for valuation, while the EQ-5D uses the TTO approach The HUI2/3 uses multi-attribute ... was extracted from their medical records The stage of cancer is typically classified from stage to stage 4; the higher the stage, the more aggressive and fast growing the cancer The ECOG-PS is a...
Ngày tải lên: 11/08/2014, 23:22
Báo cáo khoa học: " An Investigation of the Ability of the Glutaraldehyde Test to Distinguish between Acute and Chronic Inflammatory Disease in Horses" ppsx
... for the GT and laboratory analysis was collected at the same time either upon arrival at the hospital or the following day Horses having a history of clinical signs of inflammatory disease of total ... GT acts then as an indicator for further laboratory analysis of blood to determine chronicity and etiology of the disease If the test is negative, the disease is most likely acute or the systemic ... veulens (A study of the reliability of the glutaraldehyde test to determine the level of gamma globulin in the serum of foals and the suitability of this test in practice for the control of colostrum...
Ngày tải lên: 12/08/2014, 15:21
Báo cáo y học: " A polymorphism in the interleukin-4 receptor affects the ability of interleukin-4 to regulate Th17 cells: a possible immunoregulatory mechanism for genetic control of the severity of rheumatoid arthritis" doc
... significant decrease in the measured IL-17 level with the addition of IL-4 to the Th17-stimulatory conditions (Figure 1) We then further examined these groups by specific genotype In the I/I genotype ... genotypes There was a more pronounced suppression of the percentage of IL-17+ cells in the I/I genotype culture, as shown in the top row of Figure 3A, compared to the suppression of IL-17+ cells in the ... In the healthy individuals there was a significant increase in the IL-17 level after the addition of Th17-stimulatory cytokines over baseline T cell stimulation with anti-CD3 (P < 0.01), and there...
Ngày tải lên: 12/08/2014, 15:22