quantitative trait locus analysis in haplodiploid hymenoptera

... Karlsen A, Lien S, Olsaker I, Goddard ME: Fine mapping of a quantitative trait locus for twinning rate using combined linkage and linkage disequilibrium mapping Genetics 2002, 161:373-379 Olsen HG, ... Lien S: Fine mapping of quantitative trait loci on bovine chromosome affecting calving difficulty J Dairy Sci 2008, 91:4312-4322 34 Jansen RC: Interval mapping of multiple quantitative trait loci ... and linkage Genet Sel Evol 2004, 36:145-161 31 Lee SH, Van der Werf JH: The role of pedigree information in combined linkage disequilibrium and linkage mapping of quantitative trait loci in a...

Ngày tải lên: 14/08/2014, 13:21

... Schellander K: Mapping quantitative trait loci for innate immune response in the pig Int J of Immunogenet 2011, 38:121-131 39 Visscher PM, Haley CS, Knott SA: Mapping QTLs for binary traits in backcross ... Goddard C: Porcine osteochondrosis: Deficiencies in transforming growth factor-β and insulin-like growth factor-I Calcif Tissue Int 1995, 56:376-381 38 Uddin MJ, Cinar MU, Große-Brinkhaus C, Tesfaye ... was to investigate QTL for LW-related traits, including leg and feet scores, OC and bone mineral traits in a Duroc × Pietrain resource population Methods Experimental animal population In this...

Ngày tải lên: 14/08/2014, 13:21

... composition traits in sheep, and to provide additional information on QTL for these traits The application of QTL information for these traits is of potential interest in marker-assisted selection since ... lactation curve for milk, protein, fat and SCS in U.S Holstein cattle, confirming the QTL on chromosomes 6, 14, 21 and 22 identified in German Holstein Friesians, and finding additional QTL regions ... validation in terms of effect sizes and location The QTL findings also provide a foundation for targeted fine-mapping using SNP before positional candidate genes can be investigated In particular,...

Ngày tải lên: 14/08/2014, 13:21

... M., Simultaneous mining of linkage and linkage disequilibrium to fine map quantitative trait loci in outbred half-sib pedigrees Revisiting the location of a quantitative trait locus with major ... of recombination and identity-by-descent (IBD) mapping exploiting linkage disequilibrium (LD) in the New Zealand and Dutch Holstein Friesian population [21] A combined linkage and linkage disequilibrium ... QTL, only 28 contained sufficient information to be included in the meta -analysis (Tab I) We focused on the metaanalysis for results reported for BTA6 since this chromosome contained the highest...

Ngày tải lên: 14/08/2014, 13:22

... to mapping quantitative trait loci in livestock Proc 45th EAAP-Meeting, Edinburgh, UK, 5-8 September 1994 Haseman JK, Elston RC (1972) The investigation of linkage between a quantitative trait ... applying sib-pair linkage tests to livestock species Genet Sel Evol 24, 29-42 Haley CS, Knott SA (1992) A simple regression method for mapping quantitative trait loci in line crosses using flanking ... / taux de recombinaison INTRODUCTION Haseman and Elston (1972) developed the idea of detecting linkage between a marker and a quantitative trait locus (QTL) by examining the squared difference...

Ngày tải lên: 09/08/2014, 18:21

... JW, Lanini B, Tanksley SD: Fine Mapping of Quantitative Trait Loci Using Selected Overlapping Recombinant Chromosomes, in an Interspecies Cross of Tomato Genetics 1990, 124(3):735-742 Walling GA, ... Confidence Intervals in QTL Mapping by Bootstrapping Genetics 1996, 143(2):1013-1020 Meuwissen THE, Karlsen A, Lien S, Olsaker I, Goddard ME: Fine mapping of a quantitative trait locus for twinning ... rate using combined linkage and linkage disequilibrium mapping Genetics 2002, 161(1):373-379 Meuwissen THE, Goddard ME: Mapping multiple QTL using linkage disequilibrium and linkage analysis information...

Ngày tải lên: 14/08/2014, 13:21

... single milk content traits Results Results of the QTL analysis using QTL-MLE for the single milk content traits Drawn are the genome-wide graphs for the single milk contents traits for protein, ... specific traits and all known QTL locations, are user selected The browser allows within -trait and across -trait analysis of the information An example for the main milk traits,, fat protein and ... composition traits, protein, fat and lactose percentages, is shown in Figure In order to aggregate the QTL information, the integrated QTL scores for each trait are shown in Figure by way of a single...

Ngày tải lên: 14/08/2014, 13:21

... of individual components estimated by CT) A list of all traits used in this study is provided in Table A linear model was fitted using SAS (version 9.2) to adjust the scanning results for final ... bone in carcass % Proportion of bone in carcass 165 11 16 *Industry relevant refers to a trait that is used in the industry as a standard measure and hence is incorporated as a means for comparing ... mapping Marker analysis QTL mapping procedure A genome scan using 189 polymorphic microsatellite markers covering all 26 sheep autosomes was conducted in 510 backcross animals For the linkage analysis, ...

Ngày tải lên: 14/08/2014, 13:21

... interval in timing of ovulation and fertilization in cows, J Anim Sci 74 (1996) 944–949 [20] Lander E.S., Botstein D., Mapping Mendelian factors underlying quantitative traits using RFLP linkage ... C.S., Confidence intervals in QTL mapping by bootstrapping, Genetics 143 (1996) 1013–1020 [42] Wang C.S., Implementation issues in Bayesian analysis in animal breeding, in: Proceedings of the 6th ... polygenic binary traits using generalized and regression interval mapping in multi-family half-sib designs, Genet Res 76 (2000) 305–317 [19] Kemp B., Soede N.M., Relationship of weaning-to-estrus interval...

Ngày tải lên: 14/08/2014, 13:22

... [35-37] Interleukin (IL)-6 protein was increased following ZnO exposure in humans [1,38], and was hypothesized to be an anti-inflammatory suppressor of ZnO-induced lung injury Interestingly, increased ... chemokines) that signal through numerous chemokine receptors [42] PMNs are capable of producing several chemokines and proinflammatory cytokines, indicating that PMNs may be important in auto-direction ... uropathy in the mouse: role of osteopontin in interstitial fibrosis and apoptosis Kidney Int 1999, 56:571-580 Driscoll KE: Macrophage inflammatory proteins: biology and role in pulmonary inflammation...

Ngày tải lên: 12/08/2014, 18:21

... Her research interests include applications of mathematical programming in finance, in particular using disjunctive programming in modeling accounting regulations and in problems in risk management ... the parameters in Table 28 Quantitative Analysis in Financial Markets short rate in theoretical models Since the method in this paper does not rely on the sampling interval being small, the ... interest rate Applications to derivative pricing, consisting in obtaining pricing formulas for any underlying price process, have been briefly outlined and will be developed in future work Finally,...

Ngày tải lên: 23/03/2014, 12:20

... View in SPSS Value Labels window in SPSS Frequencies window in SPSS SPSS Output window Defining variables in SPSS Variable Type window in SPSS Value Labels window in SPSS Missing Values window in ... dataset as it appears in SPSS Save As window Opening SPSS in Windows XP SPSS 15.0 for Windows window in SPSS Open Data window Options window in SPSS Value labels icon in SPSS Viewing summaries of ... window in SPSS Adding a title to a chart in the Chart Editor window in SPSS Adding a footnote to a chart in the Chart Editor window in SPSS Changing the color of bars using the Properties window...

Ngày tải lên: 03/05/2014, 19:16

... ranked actin at the last position, indicating that it is an unsuitable reference gene in virus infected cells The actin gene shows significant variations with increasing degree of infection The ... expression stability The analysis of our data set according to the Bestkeeper tool revealed very good BestKeeper indices; even actin was included into our gene panel These findings demonstrate the ... 11.28), confirming to be the most inappropriate reference gene It is remarkable that the obtained BestKeeper index values are low, despite the inclusion of Act in the calculation Calculating BestKeeper...

Ngày tải lên: 18/06/2014, 22:20

... ranked actin at the last position, indicating that it is an unsuitable reference gene in virus infected cells The actin gene shows significant variations with increasing degree of infection The ... expression stability The analysis of our data set according to the Bestkeeper tool revealed very good BestKeeper indices; even actin was included into our gene panel These findings demonstrate the ... 11.28), confirming to be the most inappropriate reference gene It is remarkable that the obtained BestKeeper index values are low, despite the inclusion of Act in the calculation Calculating BestKeeper...

Ngày tải lên: 20/06/2014, 04:20

... corresponding Type I error rate at the whole genome level as explained in Saintagne et al [27] Epistatic interactions between pairs of markers were investigated by a two-factor analysis of variance using ... QTLs explaining between 2.79 and 8.11% of the phenotypic variance of rooting ability, with being detected in two consecutive years and being specific to only one year In maritime pine (C Plomion, ... parameters an QTL analysis of d13C and ring width in maritime pine, Plant Cell Environ 25 (2002) 945–953 [8] Britvin E., Minkov D., Glikson L., Ronin Y., Korol A., MultiQtl, an interactive package...

Ngày tải lên: 08/08/2014, 00:22

... SM: Fine mapping of collagen-induced arthritis quantitative trait loci in an advanced intercross line J Immunol 2006, 177:7042-7049 Kumar S, Boehm J, Lee JC: p38 MAP kinases: key signalling molecules ... Baz1b 134.1 Bromodomain adjacent to zinc finger domain, 1B NC/PI Lfng 139.5 Lunatic fringe gene NC/PI/OA 8.8/4.6/2.5 CA -7.7 Gna12 139.7 Guanine nucleotide binding protein, alpha 12 NC/PI/OA ... Genes involved in immunoinflammatory responses were differentially expressed in the blood cells in RA patients [18] Chemokines and adhesion molecules were upregulated in the joint at the initiation...

Ngày tải lên: 09/08/2014, 10:20

... Selection in parental lines to increase power for QTL mapping Selection of high ranking individuals in one parental line and of low ranking individuals in another parental line can be used to increase ... offspring should be increased in proportion to 1/( 1- 2c?to obtain the same power as with complete linkage !14! Power could be increased by using interval mapping instead of the use of a single ... the relevant information in interval mapping comes from the non-recombinant individuals The number of offspring required to obtain power as given in this paper should be increased in a proportion...

Ngày tải lên: 09/08/2014, 18:21

... introduced into the interval mapping methodology in order to improve the accuracy of QTL detection The method called composite interval mapping includes markers outside the interval being analyzed in ... obesity quantitative trait locus on mouse chromosome and evidence of linkage to body fat and insulin on the human homologous region 20q, J Clin Invest 100 (1997) 12401247 [79] Lindblad-Toh K., Winchester ... approach for mapping quantitative trait loci, Genetics 139 (1995) 14211428 [73] Lander E., Kruglyak L., Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results,...

Ngày tải lên: 09/08/2014, 18:21

... selection in Chinese × European synthetic lines, the choice of breeding animals in crossbreeding programs involving Chinese breeds or the introgression of high growth or leanness alleles in the Chinese ... containing 17% crude protein, 0.85% lysine and 100 kcal digestible energy during the whole testing period from 10 to 22 weeks of age They were weighed at the beginning and at the end of the testing ... mapping / quantitative trait locus / growth / fatness INTRODUCTION Genetic maps of the porcine genome have been developed during the last decade [3,10,32,33] More than 800 markers, including...

Ngày tải lên: 09/08/2014, 18:21

... imprinting contrasts with the numerous reports of imprinting effects in pigs recently published Knott et al [18] reported an improvement of fit for abdominal fat on SSC when including an imprinting ... of linked QTLs can be confirmed by means of new experiments that allow breaking the linkage between QTLs, for instance by developing advanced intercross lines or interval-specific congenic strains ... throughout the SSC for growth traits with significant sex-QTL interaction, by fitting two models: a single QTL model (without interaction) and a model including the sex-QTL interaction W13, W17 and...

Ngày tải lên: 09/08/2014, 18:21