ptld in hematopoietic stem cell transplantation hsct
Báo cáo y học: "Frequency analysis of TRBV subfamily sjTRECs to characterize T-cell reconstitution in acute leukemia patients after allogeneic hematopoietic stem cell transplantation" pot
Ngày tải lên :
10/08/2014, 21:23
... between sjTRECs levels in recipients at pre -HSCT and those within 12 weeks post -HSCT (including the ~4 weeks post -HSCT group, 4-8 weeks post -HSCT group, and 8-12 weeks post -HSCT group) (r = -0.197, ... post -HSCT (including the week post -HSCT, week post -HSCT, week 16 post -HSCT, and week 30 postHSCT groups) revealed that the frequencies of TRBV subfamily sjTRECs in recipients at week post -HSCT ... and reaching a plateau months after HSCT, indicating ongoing thymic output Although fludarabine-based, non-myeloablative conditioning was performed in both studies, the regimen used in the Bahceci...
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Báo cáo y học: "Marked increase of procalcitonin after the administration of anti-thymocyte globulin in patients before hematopoietic stem cell transplantation does not indicate sepsis: a prospective study" pptx
Ngày tải lên :
13/08/2014, 16:20
... online http://ccforum.com/content/13/2/R37 Key messages • Anti-thymocyte globulin (ATG) administered during conditioning before hematopoietic stem cell transplantation triggered a marked increase ... C-reactive protein, interleukin6, and procalcitonin levels in allogeneic hematopoietic stem cell recipients Eur J Haematol 2006, 76:93-101 10 Dornbusch HJ, Strenger V, Sovinz P, Lackner H, Schwinger W, ... antibody administration [8] Pihusch and colleagues [9] prospectively studied PCT, CRP, and interleukin-6 (IL-6) in 350 stem cell recipients Conditioning with ATG increased all monitored markers In neutropenic...
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ADVANCES IN HEMATOPOIETIC STEM CELL RESEARCH pot
Ngày tải lên :
27/06/2014, 13:20
... grouped into four sections: 1) Hematopoietic stem cell properties, 2) Regulation of hematopoietic stem cells, 3) Hematopoietic stem cells in aging and disease, and 4) Hematopoietic stem cell therapy ... signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo Cell Stem Cell Mar 6;2(3):274-83 Fuchs, E.(2008) Skin stem cells: rising to ... stimuli trigger intrinsic determinants of cell fate, the transcription factors which contribute to the reprogramming of HSCs into cell- Advances in Hematopoietic Stem Cell Research lineage restricted...
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Báo cáo y học: "Hematopoietic stem cell transplantation for systemic lupus erythematosus" ppsx
Ngày tải lên :
09/08/2014, 01:23
... systemic lupus erythematosus Rheumatology 1999, 38:767-772 Burt RK, Slavin S, Burns WH, Marmont A: Induction of tolerance in autoimmune disease by hematopoietic stem cell transplantation: getting ... direct comparison of HSCT with cyclophosphamide and ATG versus the Hopkins’ treatment protocol incorporating high-dose cyclophosphamide without stem cell support Competing interests None declared ... hematopoietic stem cells are infused in order to shorten the past transplant neutropenic interval by 4–6 days compared with the same dose of cyclophosphamide without hematopoietic stem cell support,...
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Báo cáo y học: "Allogeneic hematopoietic stem cell transplantation for acute leukemia with Gilbert’s syndrome" pptx
Ngày tải lên :
10/08/2014, 21:23
... phenytoin, an inducer of UGT1A1 activity used during the conditioning, prevented hyperbilirubinemia [8] It has been reported that UGT1A1 inducers, including phenobarbital, rifampin and phenytoin, ... liver dysfunction In our case, transaminase and bilirubin levels were almost normal during the conditioning and within 100 days after transplantation, although indirect hyperbilirubinemia repeatedly ... http://www.jhoonline.org/content/4/1/9 Page of Figure Bilirubin level during chemotherapy and allogeneic hematopoietic stem cell transplantation Chronological dates of the treatment courses were indicated...
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Tài liệu Review of Chronic Graft- Versus-Host Disease in Children After Allogeneic Stem Cell Transplantation: Nursing Perspective pptx
Ngày tải lên :
12/02/2014, 19:20
... GVHD is initiated, T-cells produce additional proinflammatory cytokines, including tumor necrosis fac tor (TNF)-α, interferon (IFN)-γ, and interleukin (IL)-2, which in turn attract more T-cells ... (Th2) cells can initiate a response against autoantigens leading to B -cell hyperre activity and production of autoantibodies, causing targetorgan damage, including skin, mucosa, eyes, joints, ... Consensus recom mends a system for scoring chronic GVHD manifestations in organs and sites, including the skin, mouth, eyes, gastro intestinal tract, liver, lungs, joints and fascia, genital...
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Tài liệu INNOVATIONS IN STEM CELL TRANSPLANTATION doc
Ngày tải lên :
18/02/2014, 04:20
... sibling hematopoietic stem cell transplantation On applying KIR genotyping, some studies investigated the effect of KIR in sibling HSCT A study of 220 donor-recipient pairs in HLA-matched sibling ... transplanted stem cells in the host In conclusion, Cell Transplantation is bridging cell transplantation research in a multitude of disease models as methods and technology continue to be refined The ... blood cell or a brain cell During this last decade, the number of published articles or books investigating the role of stem cells in cell transplantation or regenerative medicine increased remarkably...
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Tài liệu New Advances in Stem Cell Transplantation Edited by Taner Demirer ppt
Ngày tải lên :
20/02/2014, 08:20
... RNA binding protein and stem cell marker Inhibitor of microRNA processing in embryonic stem (ES) and carcinoma (EC) cells Table Combinations of the genes that have been used to obtain the induced ... factors into somatic cells By using these viral delivery systems, 12 New Advances in Stem Cell Transplantation Fig Methods for producing induced pluripotent stem cells (iPSCs) by non-integrating ... factor 1/PD2 maintains self-renewal by its interaction with Oct3/4 in mouse embryonic stem cells Stem Cells 27, 30013011 22 New Advances in Stem Cell Transplantation Rai, K., Huggins, I.J., James,...
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báo cáo hóa học: " Function, Adjustment, Quality of Life and Symptoms (FAQS) in Allogeneic Hematopoietic Stem Cell " potx
Ngày tải lên :
20/06/2014, 15:20
... by the inclusion of subgroups that have been understudied in prior stem cell transplant survivorship research, including Spanish speakers, and individuals undergoing reduced intensity transplantation ... current status of hematopoietic cell transplantation Annu Rev Med 2003, 54:491-512 Horowitz MM: Uses and growth of hematopoietic cell transplantation In Thomas’ hematopoietic cell transplantation ... improvement in functioning between and years post-transplant [35] In contrast, particularly in patients older than 25 at the time of HSCT, recovery may be non-linear, with functional status continuing...
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Báo cáo khoa học: " Challenging complications of treatment – human herpes virus 6 encephalitis and pneumonitis in a patient undergoing autologous stem cell transplantation for relapsed Hodgkin''''s disease: a case report" doc
Ngày tải lên :
12/08/2014, 04:21
... allogeneic stem cell transplantation, severe disease is rare in patients after autologous stem cell transplantation Nevertheless, in patients with severe complications of infections after autologous stem ... after hematopoietic stem cell transplantation Clin Infect Dis 2005, 40:932-940 Bissinger AL, Einsele H, Hamprecht K, Schumacher U, Kandolf R, Loeffler J, Aepinus C, Bock T, Jahn G, Hebart H: Infectious ... of integrated human herpesvirus-6 in allogeneic hematopoietic stem cell transplantation Bone Marrow Transplant 2007, 40:563-566 Competing interests The authors declare that they have no competing...
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Báo cáo khoa học: " Challenging complications of treatment – human herpes virus 6 encephalitis and pneumonitis in a patient undergoing autologous stem cell transplantation for relapsed Hodgkin''''s disease: a case report" ppsx
Ngày tải lên :
12/08/2014, 04:22
... allogeneic stem cell transplantation, severe disease is rare in patients after autologous stem cell transplantation Nevertheless, in patients with severe complications of infections after autologous stem ... after hematopoietic stem cell transplantation Clin Infect Dis 2005, 40:932-940 Bissinger AL, Einsele H, Hamprecht K, Schumacher U, Kandolf R, Loeffler J, Aepinus C, Bock T, Jahn G, Hebart H: Infectious ... of integrated human herpesvirus-6 in allogeneic hematopoietic stem cell transplantation Bone Marrow Transplant 2007, 40:563-566 Competing interests The authors declare that they have no competing...
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hematopoietic stem cell protocols
Ngày tải lên :
11/04/2014, 09:45
... not included in the lineage cocktail After incubating for 20 min, wash the cells twice by diluting in staining medium followed by centrifugation The cells can now either be pre-enriched using ... sorted, complete the staining by incubating in streptavidin conjugated to Texas Red or PharRed for 15–20 on ice After washing, resuspend the cells in staining medium containing a viability dye (PI ... the cell suspension, including biotinylated anti-Sca-1, APC-conjugated anti-Mac-1, and FITC-conjugated anti-Thy-1.1 After incubating for 20 min, wash the cells twice by diluting in staining medium,...
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Báo cáo y học: "Stem cell transplantation for rheumatic autoimmune diseases" potx
Ngày tải lên :
09/08/2014, 10:23
... Figure Resetting of the immunological clock following hematopoietic stem cell transplantation Hematopoietic stem cell transplantation (HSCT) is a complex multistep procedure involving mobilisation ... obtained from studies showing increases in T -cell receptor excision circles and CD31+ T cells and normalisation of new T -cell receptor repertoires [53,54] Allogeneic hematopoietic stem cell transplantation ... regulatory T cells In the proteoglycan-induced arthritis mouse model, the initial improvement after autologous HSCT corresponded to an increase in CD4+CD25+ cells [51] Initially, these T-regulatory cells...
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Báo cáo y học: "Mesenchymal stem cell transplantation ameliorates motor function deterioration of spinocerebellar ataxia by rescuing cerebellar Purkinje cell" ppsx
Ngày tải lên :
10/08/2014, 10:20
... showed that in utero transplantation of hMSCs in mice contributed to numerous tissues, including the brain and spinal cord [24] Donor hMSCs engrafted into murine tissues originating from all ... Delafontaine P, Prockop DJ: Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6 Cell Stem Cell 2009, ... Immunohistochemistry staining for human mesenchymal stem cells in whole brain sections of mice Whole brain sections of each mice (4 μm) were proceeded immunohistochemistry staining of b2 microglobulin for hMSCs...
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Báo cáo y học: "Acute myeloid leukemia of donor origin after allogeneic stem cell transplantation from a sibling who harbors germline XPD and XRCC3 homozygous polymorphisms" pps
Ngày tải lên :
10/08/2014, 21:23
... http://www.jhoonline.org/content/4/1/39 suggesting maturation into the basophil vs mast cell lineages Further immunocytochemical stainings were performed showing CD203c expression in the absence ... of stem cell infusion Discussions and Conclusions Here we report a case of a secondary AML developing from donor-derived cells in a breast cancer patient who underwent allogeneic stem cell transplantation ... polymorphisms in the patient’s pre- and post -transplantation (AML) cells and donor’s cells Polymorphism DNA repair mechanism Patient cells (pretransplantation) AML cells (posttransplantation) Donor cells...
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báo cáo khoa học: "Current status of haploidentical stem cell transplantation for leukemia" pps
Ngày tải lên :
10/08/2014, 22:20
... haploidentical T -cell- replete hematopoietic stem cell transplantation Hematologica 2007, 92:414-417 Bignon JD, Gagne K: KIR matching in Hematopoietic stem cell transplantation Curr Opin Immunol 2005, ... of donor hematopoietic stem cells by combining G-CSF mobilized peripheral blood with bone marrow stem cells, both depleted of T cells, following TBI-based conditioning regimens[16-18] In their ... stem cell transplantation using unrelated donors Blood 2004, 103:2860-2862 Lowe EJ, Turner V, Handgretinger R, et al.: T -cell alloreactivity dominates natural killer cell alloreactivity in minimally...
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báo cáo khoa học: "Multiple Myeloma Involving Skin and Pulmonary Parenchyma after Autologous Stem Cell Transplantation" potx
Ngày tải lên :
10/08/2014, 22:20
... http://www.jhoonline.org/content/2/1/48 A C B D E Figure nodules; of Wright Giemsa stain, aspirate of skin nodules; (C) Chest CT showing diffuse infiltrates; (D) H&E of BAL; (E) Skin (A) Kappa staining(B) ... autologous stem cell transplantation The presence of circulating plasma cells and hyperammonemia are both known to be indicators of advanced disease Plasma cell neoplasm should be kept in the differential ... Kappa staining(B) BAL (A) Skin nodules; (B) Wright Giemsa stain, aspirate of skin nodules; (C) Chest CT showing diffuse infiltrates; (D) H&E of BAL; (E) Kappa staining of BAL ment as a complication...
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