provision for individuality as an eighth factor in study

... Taken together, in clinical diagnosis, the change of the concentration of MHC in human serum and plasma is an important factor to examine the muscle injury and myosin-related diseases 12 1.3 The ... loops are involved in recognition of different phage protein as well as involving in conjugation and in binding of a phage and a bacteriocin (Morona et al, 1984) 1.3.3 The role of OmpA in virulence ... head and tail (Tonomura & Oosawa, 1972 ; Korn et al, 1988) Being phosphorylated by myosin light chain kinases or Rho kinases, the myosin light chain can regulate the function of myosin by changing...

Ngày tải lên: 03/10/2015, 20:32

... example, in a formal setting intelligence and aptitude play a dominant role in learning, while exerting a weaker influence in an informal setting The variables of situational anxiety and motivation ... complex One cannot simply observe input, in terms of the amount of time spent studying the language and then output, expressed as linguistic performance when investigating language learning In order ... target language and therefore, no chance to interact with members of the target group Lukmani (1972) found that an instrumental orientation was more important than an integrative orientation in nonwesternized...

Ngày tải lên: 06/09/2013, 10:10

... with b-catenin for a-catenin binding, but in fact induces a conformational change in the N-terminal region of a-catenin by binding to the C-terminal region EspB-bound a-catenin shows enhanced affinity ... a-catenin from adherence junction complexes (Fig 1) EspB also interacts with the actin-binding domain of several myosin proteins, including myosin-1a, -1c, -2, -5, -6 and -10 [12] By inhibiting interactions ... EspB binds to the C-terminal vinculin homology domain of a-catenin, whereas formation of a-catenin ⁄ b-catenin ⁄ E-cadherin complexes at adherence junctions requires the N-terminal vinculin homology...

Ngày tải lên: 29/03/2014, 09:20

... X-ray findings including diffuse densification of bone, calcifications of bony insertions of many ligaments, discs, and interosseous membranes, i.e interosseous of ribs, forearm, and leg; urinalysis ... Motor weakness in the lower extremities and difficulty in walking as initial symptoms were found in patients The details of the clinical findings are shown in table and table The mean duration of ... expression of transforming growth factor beta-1 (TGF-β1) by fibroblasts was found in the ossified matrix within ossified ligaments and in chondrocytes within cartilaginous areas adjacent to the...

Ngày tải lên: 20/06/2014, 00:20

Ngày tải lên: 20/06/2014, 00:20

... 30 Cash flow from (used in) financing activities (C) 1,120 (984) In( De)crease in cash and cash equivalents (A+B+C) 1,340 (99) Cash and cash equivalents as at January 2,456 2,698 In( De)crease in ... Financial instruments Information about accounting for derivative financial instruments and hedging activities is included in the section “Financial Risk Management” Accounting Policies 107 Financial ... 12 Financial income (expenses) Other ordinary (expenses) income net Depreciation and amortization of non-operating assets Total The increase in financial income is mainly due to an impair- In...

Ngày tải lên: 30/07/2014, 17:22

... markers in canine mammary carcinoma and female breast cancer [20,34] Positive staining of p53 protein was detected in two benign mammary tumors accompanied by increased index of MIB-1 in this study ... sample was regarded as p53 positive if nuclear staining was clearly detected, but cytoplasmic staining alone was not recorded as positive Positively staining was evaluated semi-quantitatively using ... recent study by Rohan et al [23] concluded that p53 staining in benign breast biopsies was associated with an increased risk of future breast cancer Thus, p53 protein levels of wild type or mutant...

Ngày tải lên: 07/08/2014, 17:22

... Table p27 and cyclin E statistical associations p27 Cyclin E All invasive carcinomas Infiltrating duct carcinomas only All invasive carcinomas Infiltrating duct carcinomas only Distant metastases ... disease in invasive lobular carcinomas but not in invasive ductal carcinomas Another study evaluated the bio-molecular differences between ductal and lobular carcinomas in 190 in ductal and 67 ... duct carcinomas The results of the study conducted by Sasano et al (21 invasive duct carcinomas and 19 invasive lobular carcinomas) showed that there was no significant difference in the means of...

Ngày tải lên: 09/08/2014, 01:24

... with the indicated FITC-conjugated antibodies (0.5 µg) for 30 min, washed twice and incubated for 30 with the indicated PE- or biotin-conjugated antibodies For the biotin-conjugated antibodies, ... mg of anti-CD25 (PC61) or control IgG antibodies, for weeks (injected intraperitoneally) Histological examination Forelimbs and hindlimbs were fixed in 10% formalin and decalcified with formic ... were incubated for 15 with the Fc-receptor-blocking antibodies antiCD16/anti-CD32 (CD16/CD32; BD Biosciences Pharmingen, San Diego, CA, USA) Cells were washed with PBS containing 2% FCS and stained...

Ngày tải lên: 09/08/2014, 06:22

... final manuscript Acknowledgements The authors thank Anders Strand for technical assistance and for performing the precision studies for the hand bone measurements They also thank Stian Lydersen for ... the change in the DXA hand and in the DXA total hip and spine were 0.35 (P < 0.001) and 0.18 (P = 0.01), whereas correlations between the change in the DXR hand and DXA total hip and spine were ... be used as a marker for disease activity and bone loss during the whole disease process, both in early disease as well as prolonged disease The reason for this discrepancy is not clear and additional...

Ngày tải lên: 09/08/2014, 10:20

... causing a stroke, which was his presenting complaint The patient was anticoagulated with warfarin and secondary prevention instituted with angiotensin-converting enzyme (ACE) inhibitor, statin and ... knowledge, in a middle-aged man in association with anti-cardiolipin antibodies Treatment of SCAD, although lacking in consensus, depends on the clinical situation If the patient is asymptomatic and ... conservative management is advised, as in the case of our patient Successful revascularization in acutely unwell patients, in the form of percutaneous coronary intervention [12] and coronary artery bypass...

Ngày tải lên: 11/08/2014, 12:20

... citrullinated Fibβ and Fibγ in RA synovium has been reported by Matsuo et al [25] Based on these findings, immunodetection was performed with anti-Fibβ, anti-Fibγ, anti-fibronectin and anti-vimentin ... performed using respectively rabbit anti-human Fibβ, rabbit anti-human Fibγ and rabbit anti-human fibronectin Anti-rabbit HRP labelled antibody was used as a secondary antibody ECL detection was carried ... proteins in IC from RA SF were identified as vimentin and Fibβ The fact that vimentin was found as antigen during D analysis and not during the broad range proteome approach with D SDS PAGE, can...

Ngày tải lên: 12/08/2014, 14:22

... of gastric emptying and fasting cholecystokinin and peptide YY concentrations Relationship between the rate of gastric emptying (measured using an isotope breath test and calculated as the gastric ... in animals [30], and this may also be the case in humans (Dr G Kostuic, personal communication) Pharmacological doses of ghrelin also increase fasting blood glucose and suppress plasma insulin ... glucose-lowering reflects slower gastric emptying, as well as increased insulin and decreased glucagon secretion [66-68] Pharmacological doses of GLP-1 reduce both fasting and postprandial glycaemia...

Ngày tải lên: 13/08/2014, 20:22

... markets in the past (activity following the 1997 Asian Financial Crisis is a prime example of this as discussed in Chapter 3.1) In encouraging tourism, Malaysia has demonstrated strong planning and ... as sales packs) requested due to knowing what information was required rather than seeing what was available Pulau Langkawi is a small island and the list of hotels was short As such, only nine ... it into quantitative data As I was based in Kuala Lumpur, my interviews there took place over a longer period and were less structured as a result In many cases, I met people by chance or was...

Ngày tải lên: 26/09/2015, 12:48

... 30 generate an activated integrin state at the cell surface.The integrin-binding proteins paxillin and talin recruit focal adhesion kinase (FAK) and vinculin to focal contacts -Actinin is a cytoskeletal ... possessing the HECT (homologous to the E6-AP carboxyl terminus) domain and those containing the RING (really interesting new gene)-finger domain (41, 43) 27 The RING-finger domain is a zinc finger ... Tyrosine Kinase RING Really Interesting New Gene si-RNA small interfering RNA IX SOCS Suppressor of Cytokine Signaling SPRY SPla and RYanodine receptor TRIM Tripartite Motif-containing Ub Ubiquitin...

Ngày tải lên: 20/05/2016, 15:30

... E-cadherin to promote metastasis in cells overexpressing oncogenic Ras Another ability that is acquired by mammalian tumors is degradation of basement membranes Using an antibody to detect laminin and ... involved in protein-protein interactions) and discs large encodes a member of the membrane-associated guanylate kinase (MAGUK) family that contains multiple PDZ domains known to be involved in ... specific combination of genetic changes that together induce metastasis Pagliarini and Xu [10] asked whether the metastasis observed in RasV12scrib- cells exhibits features of human metastatic tumors...

Ngày tải lên: 09/08/2014, 20:20

... biodiversity conservation) PROMOTING PES IN LAO PDR SLIDE 27 Private and government investments in ecosystem services can financially compensate landowners for protecting and enhancing the nation’s natural ... conserving large areas, as selling one service may be insufficient for covering all conservation costs In addition, bundling can be especially helpful for biodiversity conservation, as it can be ... ecosystems, and natural resources, provide stability and maintenance for land and water systems, and sustain national, provincial, and local economies in ways that are only now becoming apparent...

Ngày tải lên: 26/05/2016, 20:58

... performed using the WilcoxonMann-Whitney rank sum tests for continuous outcomes (transfusions, time on ventilator, and time in ICU), and Fisher's exact test was used for binary outcomes (massive transfusion, ... in the placebo and recombinant activated factor VII (rFVIIa) groups products and inherent risk factors for immunological and infectious risks It is known that with increasing transfusion requirements, ... Transfusion medicine service policies for recombinant factor VIIa administration Transfusion 2004, 44:1325-1331 37 Vaslef SN, Knudsen NW, Neligan PJ, Sebastian MW: Massive transfusion exceeding 50 units...

Ngày tải lên: 13/08/2014, 03:20

Ngày tải lên: 08/08/2012, 17:20

... to that obtained for other serpins, including a1-antitrypsin and a1-antichymotrypsin [19,20] In comparison, the spectrum of Ser52Arg neuroserpin shows an increase in both b-sheet and a-helical ... neuroserpin (ÆÆÆÆ) and Ser52Arg neuroserpin polymers (- - -) and mutant neuroserpin The proteins were added to increasing concentrations of urea, and the change in fluorescence profile was followed ... superfamily such as a1-antitrypsin [21], antithrombin [22], C1 inhibitor [23,24] and a1-antichymotrypsin [25] in association with cirrhosis, thrombosis, angio-oedema and emphysema, respectively Indeed...

Ngày tải lên: 07/03/2014, 16:20