provide access to raw resources in resource managing classes

... Item 14: Think carefully about copying behavior in resource- managing classes Item 15: Provide access to raw resources in resource- managing classes Item 16: Use the same form in corresponding uses ... pointers, so an iterator acts much like a T* pointer Declaring an iterator const is like declaring a pointer const (i.e., declaring a T* const pointer): the iterator isn't allowed to point to ... source files will include them), it's important that the pointer be declared const, usually in addition to what the pointer points to To define a constant char*-based string in a header file,...

Ngày tải lên: 19/08/2015, 01:19

... is the inhibition by serine proteinase inhibitors (serpins) The serpins form a family of homologous, large (glyco-) proteins comprising about 400 amino acid residues Serpin inhibitors interact ... efficiently inhibitory complexes with the serpins plasminogen activator inhibitor (PAI-1) and protein C inhibitor (PCI), which both are present in DESC1expressing tissue [6] The stable inhibitory complexes ... SEA domain would directly in uence the binding of either substrates or inhibitors into the active site cleft of the DESC1 Instead, because SEA domains are proposed to bind O-glucosidic-linked proteoglycans...

Ngày tải lên: 19/02/2014, 00:20

... on in vitro T14-induced toxicity in rat hippocampal organotypic cultures Cultures were maintained in serum-free medium in the presence of indicated concentrations of T14 and alpha-bungarotoxin ... outgrowth, by inducing an in ux of calcium [4–7] However, at higher doses, or with longer exposure, sustained calcium entry can be toxic to neurons [8–10] Notably, a further determining factor in whether ... a7-nAChR in readiness for the indirect effect of R-AChE acting on (B) MLA ife E540 A Induced AChE release as percent unstressed control Fig Potential signalling mechanism involving T-AChE C-terminal...

Ngày tải lên: 23/03/2014, 07:20

... at 20-cm intervals on a subsample of four trees to examine taper Total plant height (H) was measured to the nearest 0.5 cm with an aluminium levelling rod At the end of the second year (in Afsnee ... differs olating Volume index versus as soon as dry mass The estimation of stem dry mass by means of volume index data integrates incertainties due to both real volume estimation and In other respects, ... Within the interest of land set aside programmes in industrialized countries, a joint European research program was initiated as a collaborative study between the Universities of Antwerpen, Edinburgh...

Ngày tải lên: 08/08/2014, 18:21

... choosing to bring disability into the world He argues that it is morally wrong in such a situation to choose to bring a disabled child to birth This wrong might be classiWed as ‘the wrong of bringing ... gained by living, that individual has not been wronged by being brought to birth It may well be that it does not make sense to talk of someone being made better or worse oV by being brought into ... condition is predicted to be so bad that it would not have a worthwhile life, a life worth living, then it will always be in that child’s interests to be brought into being It is in the interests of any...

Ngày tải lên: 01/11/2013, 08:20

... additional information (“SAI”), and certain other information 14 Mutual funds are required to maintain a current prospectus, which provides investors with information about the fund, including its investment ... out as being engaged primarily, or proposes to engage primarily, in the business of investing, reinvesting, or trading in securities.” 33 The term “security” is defined as “any note, stock, treasury ... funds are permitted to provide investors with a “summary prospectus” containing key information about the fund, while making more information available on the Internet and in paper upon request...

Ngày tải lên: 19/02/2014, 14:20

... Being ignored can be distressing to a patient and may delay remedial treatment Following injury, it is important for clinicians to take extra pains to ensure continuity of care and to maintain ... training, and resources to manage an incident Among the most important is training in communicating bad news Many caregivers have not been adequately educated or trained in the skills needed to ... responds to an incident reflects its progress toward becoming a learning organization Guiding Principles Two principles guide the recommendations in this document for responding to incidents:...

Ngày tải lên: 07/03/2014, 10:20

... residues are in close proximity to the ATP-binding domain The CD data indicate ATP binding with co-operativity and a Kd of 230 lM The ATP binding to PfPDO was confirmed by crosslinking to 8-azido-ATP ... buffer and insulin The reaction was started by the addition of mM dithiothreitol to both cuvettes Increasing turbidity from precipitation of the insulin B chain was recorded at 650 nm The stock solution ... completely inactive, demonstrating the predominant role of the redox site at the C-terminus in the oxidative activity The action of PfPDO in catalysing interchange of intramolecular disulfides in scrambled...

Ngày tải lên: 16/03/2014, 16:20

... complete information on relevant indicators to local and state programs, providers, and to consumers, including parents • Provide training and consultation to local provider groups in using MCH ... issues • Provide resources for state programs to establish statewide clearinghouses and resources such as toll-free hotlines Provide health education training to local public health providers ... appropriately trained practitioners in the state Ensure access for staff to continuing education and training in public health skills and competencies Monitor and provide relevant professional training through...

Ngày tải lên: 28/03/2014, 09:20

... Identifying Leading Indicators / 187 Matrix to Align Incentives / 197 ◆ CD-ROM Contents Tool Tool Tool Tool Tool Tool 1.1 1.2 1.3 2.1 2.2 2.3 Tool 2.4 Tool Tool Tool Tool Tool Tool Tool 2.5 3.1 ... for maintaining focus, being grounded in the real constraints facing the organization, collaborating with people who have the resources, talent, and willingness to contribute to accomplishing the ... tools in this chapter: • Tool 7.1: How to Use Project Plans and Action Plans for Giving Feedback • Tool 7.2: How to Use Meeting Guidelines to Give Feedback • Tool 7.3: How to Obtain and Use Internal...

Ngày tải lên: 02/04/2014, 18:07

... love to fade quickly The amount of horizontal space between two lines of text – leading is measured from baseline to baseline A healthy balance between point size and leading can keep things together ... point size So measure however you want – points, picas, inches, centimeters, or (gulp) millimeters Just remember to always print a test page before committing to a size 12 POINTS = PICA POINT ... natural to want to make beautiful type together Maybe it’s time to start thinking about expanding your family If you decide to create your own typeface, the fertility experts at FONTSTRUCT.COM can provide...

Ngày tải lên: 27/05/2014, 12:50

... cytokines like epidermal growth factor and transforming growth factor, which antagonize the effects of host cytokines mediating the antiviral process [16,26] In addition, inducing apoptosis in ... response in infected hosts by inhibiting the synthesis and release of IL-1 from infected cells; encoding soluble cytokine receptors for tumor TNF-α, TNF-β, IL-1, and importantly, IFN-γ; synthesizing ... cell-mediated immunity In order to gain more insight into the processes underlying the possible immune stimulating effect of vaccination with SPPV, the ex-vivo levels of IL-12, SOD in splenic macrophages,...

Ngày tải lên: 18/06/2014, 22:20

... cytokines like epidermal growth factor and transforming growth factor, which antagonize the effects of host cytokines mediating the antiviral process [16,26] In addition, inducing apoptosis in ... response in infected hosts by inhibiting the synthesis and release of IL-1 from infected cells; encoding soluble cytokine receptors for tumor TNF-α, TNF-β, IL-1, and importantly, IFN-γ; synthesizing ... cell-mediated immunity In order to gain more insight into the processes underlying the possible immune stimulating effect of vaccination with SPPV, the ex-vivo levels of IL-12, SOD in splenic macrophages,...

Ngày tải lên: 20/06/2014, 04:20

... progression of the lesion towards union (figures and 4) A month interval from radiotherapy to re-presentation indicates that there was an initial satisfactory response to bone pain alleviation but the ... fractures are often subjected to distractive forces inherent in lifting and pulling [11] Although radiotherapy has been shown to help relieve pain in myeloma bone disease with success rates of 50-80% ... impairs or prevents fracture healing, particularly if the malignant cells continue to destroy bone The radiotherapy administered in this case has once again led to radiographic resolution of the...

Ngày tải lên: 20/06/2014, 04:20

... bottom of the teeth You will get a better drawing if you stay away from trying to draw the teeth themselves Instead, lightly draw the outline of them using the gum line, then lightly draw lines ... When drawing mouths, knowing how the muscles of the face work is definitely to your benefit Looking in the mirror and studying how they move is one of the easiest ways to start! The Bottom Lip ... draw a thin, dark line This is actually where you can start drawing the lips, as it will be easier to draw the shapes for the top and bottom Step 4: KEEP IT SIMPLE ALREADY! Stop getting caught...

Ngày tải lên: 29/06/2014, 00:20

... person gain can be used fairly well in this field while it can be unsuitable to apply in the other one As a result, it is the knowledge only gained in a long- term trial in university which brings ... them in getting used to dealing with problems in their lives or their future careers in particular Lastly, specialized knowledge on a certain field of study a person is most interested in plays ... are interested in However, most cases agree that career preparation is the most driving force for students to enroll in a college or university First of all, one can acquire certain knowledge In...

Ngày tải lên: 22/07/2014, 04:20

... breaths/min; minute ventilation: l/min) A positive end-expiratory pressure of cmH O was applied A Foley catheter was inserted into the urinary bladder through a suprapubic cystostomy Upon Figure Photograph ... is known to result in mechanical deformation of the wound edge tissue [13-15], which results in shearing forces at the wounddressing interface that will affect the cytoskeleton [16] and initiate ... mg/kg) Before surgery, a tracheotomy was performed and an endo-tracheal tube was inserted Anaesthesia was maintained with a continuous infusion of ketamine (Ketaminol® vet 50 mg/ml; 0.4-0.6 mg/kg/h)...

Ngày tải lên: 10/08/2014, 09:21

... perceptions to provide new insights relating to task shifting Findings demonstrated that quality of counseling by lay nurse aides when supported by job aids is non-inferior to counseling provided ... recommended for non-inferiority studies Page of 14 [34,35] The inclusion of protocol violators in intention to treat analyses increases the likelihood of finding noninferiority since differences ... their existing integration within health system and local community Provide supportive supervision and clinical mentoring within function of Task shifting approach included capacity building of nurse-midwives...

Ngày tải lên: 10/08/2014, 10:23

... Domain from amino acid 159-218 essential for myosin binding Prevents bacterial phagocytosis via inhibition of myosin-actin interaction Citrobacter expressing EspB mutated for myosin binding are ... several effector proteins to promote bacterial adhesion After binding to the epithelial cell, EPEC uses the T3SS to inject effectors into the host cell cytoplasm via a needle-like structure Intimate ... death NleH1 NleH2 Bax inhibitor-1 (BI-1) Binds to N-terminal amino acid 140 of BI-1 N-terminal aa 1-100 of NleHs not required for binding to BI-1 Inhibition of apoptosis induced via multiple stimuli...

Ngày tải lên: 11/08/2014, 06:22

... the N-terminal end of the AtGCSI, are sufficient to retain a reporter protein in the ER [44] The AtGCSI cytosolic domain of 51 aa contains six arginine residues including four arginines located ... proteins containing an arginine motif are targeted to the ER remain to be investigated GCS90 and derivated constructs appear as excellent tools to study these mechanisms in plant cell The luminal ... residues in the cytosolic tail of AtGCSI contain ER localization information In order to define whether arginine residues within the first 13 aa of GCS90 play a key role in ER targeting, these...

Ngày tải lên: 12/08/2014, 03:21