proteins of iron homeostasis

... GSEA of transcriptome data using an individually designed metal homeostasis category Surprisingly, GSEA of MapMan categories did not reveal hits of the transport metal category in each of the ... significant alterations of gene expression patterns of an entire category of genes representing the components for metal homeostasis Over Representation Analysis (ORA) of 258 differentially expressed ... S3: Annotated gene list of the self-defined category “metal homeostasis Additional file 6: Table S4: Gene list of the self-defined category metal homeostasis. txt Page 10 of 10 10 Additional file...

Ngày tải lên: 11/08/2014, 11:20

... Molecular control of iron homeostasis 2.3.1 Regulation of cellular iron homeostasis The expression of some iron homeostasis- related genes has been shown to be involved in the modulation of transcription, ... Regulation of systemic iron homeostasis, 33 2.3.2.1 Systemic iron regulators, 33 2.3.2.2 Hepcidin is an iron regulatory effector, 34 2.4 Diseases related to impairment of iron homeostasis, 35 2.4.1 Iron ... Biological importance of iron, 23 2.1.2 Iron and free radical production, 23 2.2 Iron homeostasis, 24 2.2.1 Systemic iron homeostasis, 24 2.2.1.1 Iron absorption, 24 2.2.1.2 Iron excretion, 26 2.2.2...

Ngày tải lên: 16/09/2015, 15:55

... method, a majority of the people in the lower part of the river is dissatisfied with the quality of tap water Moreover, in case of accidental spill of pollutant, the distribution of water should ... Sampling point of this study Fig Development areas of bankfiltrate - 134 - Journal of Water and Environment Technology, Vol.1, No.2, 2003 Nanofiltration to hardness removal Nanofiltration experiment ... DISCUSSION Nanofiltration of hardness removal Three types of nanofiltration membrane such as UTC-60(TORAY), NTR729-HF(NITTO DENCO) and UTC-20(TORAY) was used The characteristics of membrane were...

Ngày tải lên: 05/09/2013, 08:40

... fused proteins (Fig S1B) Intracellular localization of the wt minor proteins and their fusion variants Distribution of the fused minor capsid proteins was followed through the analysis of confocal ... Recently, viroporins of RNA viruses (such as 6K protein of Sindbis virus, E protein of mouse hepatitis virus, M2 protein from influenza A, 2B and 3A proteins of poliovirus, or p7 and NS4A of hepatitis ... levels of apoptotic markers during the late stages of MPyV infection However, comparison of the levels of apoptotic markers and cytotoxicity during the replication of wt MPyV, and replication of...

Ngày tải lên: 16/02/2014, 09:20

... coordinating proteins Iron sulfur clusters are one of the most ancient and versatile cofactors of several important class of proteins and have been implicated in variety of functions [29,30] Iron and ... assembly of the iron sulfur cluster in WhiB proteins (A) The upper panel is an autoradiogram showing IscS-dependent incorporation of radioactive sulfur in the iron sulfur cluster of all seven WhiB proteins ... the iron sulfur cluster was resistant to the denaturing effect of m urea The ability of the iron sulfur cluster to survive the effects of protein denaturants is a feature of high potential iron ...

Ngày tải lên: 18/02/2014, 12:20

... increase during formation of a mating projection [28] Furthermore, homologues of oxysterolbinding proteins, a family of proteins that regulate the synthesis and transport of sterols, were found ... maintenance of cell polarity (e.g by counteracting lateral diffusion of polarized proteins within the membrane) [58,62] Alternatively, sterols may be important in the association of proteins involved ... bands, TLC plates were dipped into a charring solution consisting of 0.63 g of MnCl2Æ4H2O, 60 mL of water, 60 mL of methanol and mL of concentrated sulfuric acid, briefly dried and heated at 100 °C...

Ngày tải lên: 18/02/2014, 13:20

... absence of ALLN, smears of ubiquitinated proteins were not observed in control and TRAIL-treated canine chondrocytes In the presence of ALLN, marked accumulation of polyubiquitinated proteins ... a wide range of responses, depending on cell type and levels of ROS within the cell [23,24] The aims of this study were to investigate the major signalling pathways and effects of hypoxic conditions ... Evaluation of articular cartilage after experimentally induced osteoarthritis (A) Photomicrographs of articular cartilage (B) The evaluation of osteoarthritis in the right and left joints of dogs...

Ngày tải lên: 18/02/2014, 14:20

... for binding of 125I-labelled DS Isogenic mutants of AP1 (BM27.6, MC25, BMJ71), of 90–226 (90–226 emm1::Km), of M5 (DM5) and of JRS4 (JRS145), lacking expression of the indicated M proteins, were ... interaction as the binding of 125I-labelled DS was reduced to isogenic derivatives of the AP1 strain lacking either of these surface proteins (Fig 2) The significance of the M1 protein further ... shown) M proteins mediate the binding of GAGs to streptococci To establish the role of M proteins for the GAG interaction we again first focused on the AP1 system AP1 expresses two members of the...

Ngày tải lên: 20/02/2014, 11:20

... binding of ligands on the iron of Fe(porphyrin))13G10 complexes: (A) binding of H2O2 on the iron of 13G10-(Fe(ToCPP), (B) binding of two CN± ligands on the iron of 13G10-(Fe(ToCPP), (C) binding of ... Binding of cyanide to the iron( III) of Fe(ToCPP) and Fe(ToCPP))13G10 First of all, the aforementioned results show that the iron( III) of the Fe(ToCPP))13G10 complex is able to bind, like that of free ... imidazole on the iron of 13G10±Fe(ToCPP) is even more dif®cult than the binding of two 1-substituted imidazoles on the iron of free Fe(ToCPP) In addition, the in¯uence of the nature of the substituent...

Ngày tải lên: 21/02/2014, 03:20

... consequence of the sharing of a constant amount of LD between an increasing number of cells From our measurements, and in agreement with published data [16,17], we found that LD typically consists of ... well-established concept of flux-balance analysis (FBA) [7], a structural network model that replaces a full kinetic description which, because of a lack of experimental parameters, is as yet out of reach FBA ... previous implementations of stationary and dynamic FBA [9– 13] insofar as we experimentally determined the time dependence of glucose and ethanol concentrations, as well as of cell mass (growth)...

Ngày tải lên: 16/03/2014, 04:20

... show that it is one of the major targets of nitrosylation in K pinnata Nitrosylation of the small subunit of Rubisco does not occur in the absence of biotin or the presence of GSH, and is not ... PEG-4000 precipitation of major soluble proteins 16 kDa polypeptide was in fact the small subunit of Rubisco and also to reveal other low-abundance nitrosylated proteins of K pinnata leaf extracts ... K Abat et al S-nitrosylated proteins of Kalanchoe pinnata, a CAM plant Metabolic enzymes Proteins involved in photosynthesis Cytoskeleton proteins Stress related proteins Protein involved in...

Ngày tải lên: 16/03/2014, 06:20

... 315-318 Page of 14 Caption of figures Fig X-ray diffraction pattern of alpha phase iron oxide nanowires Fig SEM and TEM Images of Fe2O3 nanowires and precursors a) The SEM image of ip t Fe2O3 ... that can reveal the electrochemical mechanism of reactions Fig shows the first three cycles of CV curves of Page of 14 the nanowires in the range of 0.01-3 V It is clear that there is a substantial ... of the inner part of the single nanowire The HRTEM image clearly shows the microstructure of the individual grains, which confirms the polycrystalline structure of the nanowires The spacing of...

Ngày tải lên: 20/03/2014, 13:05

... the TFE sample is presented In spite of the poor effect, the spectrum indicates the presence of the Eu3+ ions in the TiO2 anatase lattice [22] The presence of iron ions together with their valence ... neighbouring shells of the absorbing species (Fe, Ti) In the case of ␣-Fe2 O3 , the first maximum of FT corresponds ˚ to the nearest oxygen neighbours, at a mean distance of 2.03 A (Table 1) The ... effect ¨ of the rare-earth doping 57 Fe Mossbauer spectroscopy reveals the presence of isotropic electronic relaxation effects as a result of spin–spin interaction between the electronic spins of neighbour¨...

Ngày tải lên: 20/03/2014, 13:08

... Synthesis of nanorods 2.1 Materials The mixture for the synthesis of iron oxide nanorods contained mL of freshly dried [BMIM][Tf2 N], 40 ␮L (0.13 mmol) of oleic acid, 43 ␮L (0.09 mmol) of oleylamine ... as the final product 2.4 Synthesis of nm nanocubes The typical synthetic mixture contained mL of [BMIM][Tf2 N] and 80 ␮L of oleic acid (∼0.25 mmol) The amount of iron pentacarbonyl used was 33 ␮L ... of hexane and then centrifuged at 8000 rpm for 10 2.5 Synthesis of 13 nm nanocubes The typical synthetic mixture contained mL of [BMIM][Tf2 N] and 48 ␮L (0.15 mmol) of oleic acid The amount of...

Ngày tải lên: 20/03/2014, 13:08

... magnetization at K of the asprepared sample in an applied field of T is as large as 56 Am2 =kg, arising from the magnetization of metallic Fe and its oxides Assuming a magnetic moment of 2:2mB per iron atom ... sample and EDX analysis of the air-oxidized sample as discussed below indicate a considerable weight percentage of iron and its compounds in the samples The morphologies of the as-prepared products ... profiles of the Fe-doped tungsten oxide nanorods after annealing in air The inset shows the morphology of the annealed sample and the area for recording EDX spectrum other iron oxides because of the...

Ngày tải lên: 20/03/2014, 13:08

... growth of a virulent strain of M tuberculosis in the spleen and lungs of female Balb/C mice It was concluded that an excess of Fe might enhance the growth of M tuberculosis and worsen the outcome of ... ,0·001 NS Statistical significance of effect (ANOVA, P) Table Indicators of iron nutrition status in the placebo group (group 1), iron- supplemented group (group 2), and iron þ other haematinics-supplemented ... controls (P, 0·01) Of 129 patients who completed months of intensive Table Indicators of disease status in the placebo group (group 1), iron- supplemented group (group 2) and iron þ other haematinicssupplemented...

Ngày tải lên: 22/03/2014, 18:20

... about the physiological relevance of these data Molecular chaperones consist of several groups of proteins that suppress the aggregation of unstable intermediates of proteins and are implicated in ... recognition of annexin I [22] Thus, there are a number of modes of interaction between members of the annexin family and those of the S100 family Although the precise physiological significance of these ... [25] Identification of the in vivo S100A12 target proteins, and characterization of their mode of interaction with S100A12, is essential to determine the exact contribution of the S100A12-dependent...

Ngày tải lên: 30/03/2014, 15:20

... the transfer of the 20-kDa protein across the chloroplast envelope The second domain consists of residues 48–72 and has features characteristic of transit peptides for transfer of proteins through ... Characterization of the fourth extrinsic protein in PS II (Eur J Biochem 270) 4159 Fig Phylogenetic analysis of the 20-kDa protein sequence (A) Alignment of the mature part of the 20-kDa protein sequence of ... conserved replacement of the residue in some of the species, and single dots indicate a slightly less conserved replacement of the residue in some of the species (B) Phylogenetic tree of the PsbQ protein...

Ngày tải lên: 31/03/2014, 07:20

... presence of cycloheximide as described above Ubiquitination of BGT/Tob family proteins HEK293 cells were transfected with several combinations of 4.5 lg of pCI-neo-HA-ubiquitin and 0.5 lg of pCI-neo-T7(a ... (Eur J Biochem 269) Fig Stabilities of GFP fusion proteins containing the C-terminal regions of BTG/Tob family proteins (A) Schematic representation of chimeric proteins, GFP–BTG1 (111–171), GFP–BTG2 ... the protein levels of Tob and b-actin were analyzed as described in (A) Fig Effects of the proteasome inhibitor on the levels of BTG/Tob family proteins T7-tagged BTG/Tob family proteins, T7-BTG1...

Ngày tải lên: 31/03/2014, 21:21

... Distribution of Iron Deficiency Acquired Iron Deficiency Genetic Forms of Iron Deficiency Clinical Stages of Iron Deficiency Symptoms and Signs of Iron Deficiency Treatment of Iron Deficiency Iron Overload ... Communication Between Iron Donor and Iron Acceptor Cells Maintenance of Iron Balance in Cells Contents x 9.3 Iron Absorption in Disorders of Iron Metabolism 9.3.1 9.3.2 9.4 Iron Deficiency 9.4.1 ... Chemistry of Iron in Biological Media Aqueous Solution Chemistry of Iron Oxygen Free Radicals Iron Hydrolysis – A Ubiquitous Phenomenon Hydrolysis of Iron( III) in Acid Media – Formation of Polynuclear...

Ngày tải lên: 11/04/2014, 09:48