... blacks is typically of the trans type, while that of the Southeast Asians is of the cis type. Regardless, patients typically have mild microcytosis and a mild anemia. The deletion of three ␣ -globin ... seminiferous tubules of the testes of the male from the time of sexual maturity onward throughout adulthood. Spermatogonia are found at the periphery of the tubules. These spermatogonia are of several ... similar damages that result from the use of or inability to use the work, even if any of them has been advised of the possibility of such damages. This limitation of liability shall apply to any claim...
Ngày tải lên: 19/06/2014, 15:20
PRINCIPLES OF INTERNAL MEDICINE - PART 3 pdf
... therapy, is of- ten fatal VI-27. The most common source of bacterial infection of intravenous cannulas is (A) contamination of fluids during the manufacturing process (B) contamination of fluids during ... to half of all cases of cardiotoxicity occur 6 months or more after completion of therapy. Efforts to limit cardiotoxicity and thereby enable the administration of a higher total dose of anthra- cycline ... be of greatest help in the immediate man- agement of this boy would be (A) blood culture (B) examination of a blood smear (C) biopsy of an axillary lymph node (D) aspiration and Gram stains of...
Ngày tải lên: 19/06/2014, 15:20
PRINCIPLES OF INTERNAL MEDICINE - PART 4 pdf
... inva- sion by a tumor (C) An echocardiogram would offer absolute proof of the diagnosis (D) The lack of pulsus paradoxus could suggest the presence of an atrial septal defect (E) Heparin and IV nitroglycerin ... from loss of position sense characteristic of tabes dorsalis. About 10% of patients with late untreated syphilis experience cardiovascular complications, usually in the form of aneurysms of the ... successful resuscitation of a patient with cardiac arrest depends on the rapidity of the initiation of resuscitative efforts, the clinical status of the patient before the arrest, and the mechanism of the event....
Ngày tải lên: 19/06/2014, 15:20
Principles of Engineering Mechanics Second Edition pdf
... study of the motion of material bodies and of the associated forces. The study of motion is called kinematics and involves the use of geometry and the concept of time, whereas the study of the ... vector sum of the external forces acting on a particular set of particles equals the total mass times the acceleration of the centre of mass, irrespective of the individual motion of the separate ... Kinetics of a particle in plane motion, 21 Introduction. Newton’s laws of motion. Units. Types of force. Gravitation. Frames of reference. Systems of particles. Centre of mass. Free-body...
Ngày tải lên: 27/06/2014, 05:20
PRINCIPLES OF CONDUCT IN ELECTRONIC COMMERCE pdf
... must be assured. The Principles are conceived as a statement of policy by the companies subscribing to these Principles. No specific means of control of the respect of the Principles is organised ... following principles. 3. Scope of the Electronic Commerce Principles These Principles apply to all our Electronic Commerce. These Principles apply in their entirety. 4. General principles of Electronic ... the attention of the users of these Principles is drawn to the fact that some principles even if they are in the form of unilateral declarations could be legally enforced. These Principles are...
Ngày tải lên: 28/06/2014, 12:20
Chapter 005. Principles of Clinical Pharmacology (Part 6) pdf
... Response Chapter 005. Principles of Clinical Pharmacology (Part 6) Principles of Dose Selection The desired goal of therapy with any drug is to maximize the likelihood of a beneficial effect ... an understanding of the relationships between plasma concentration and anticipated effects. For example, measurement of QT interval is used during treatment with sotalol or dofetilide to avoid ... concentration and beneficial or adverse drug effect, measurement of plasma levels can provide a valuable tool to guide selection of an optimal dose. This is particularly true when there is a...
Ngày tải lên: 06/07/2014, 08:20
Chapter 062. Principles of Human Genetics (Part 1) pdf
... information of eukaryotic genomes Online Mendelian Inheritance in Man http://www.ncbi.nlm.nih.gov/omim/ Online compendium of Mendelian disorders and human genes causing genetic disorders Office ... disorders Office of Biotechnology Activities National Institutes of Health www4.od.nih.gov/oba/ Information about recombinant DNA and gene transfer Site URL Comment biology. Software for ... and Molecular Bases of Inherited Disease (OMMBID) http://genetics.accessmedicine.com Online version of the comprehensive text on The Metabolic and Molecular Bases of Inherited Disease,...
Ngày tải lên: 07/07/2014, 01:20
Chapter 062. Principles of Human Genetics (Part 17) pdf
... focuses on a panel of mutations that are particularly frequent (often taking the ethnic background of the patient into account), but a negative result does not exclude the presence of a mutation ... involved in the pathogenesis of complex disorders (Table 62-1). The presence or absence of certain haplotypes may also become relevant for the customized choice of medical therapies (pharmacogenomics) ... Chapter 062. Principles of Human Genetics (Part 17) Genotypes describe the specific alleles at a particular locus. For example, there are three common alleles (E2, E3, E4) of the apolipoprotein...
Ngày tải lên: 07/07/2014, 01:20
Chapter 062. Principles of Human Genetics (Part 27) pdf
... products of variable length, depending on the number of CAG repeats. After characterization of the alleles in the parents, transmission of the paternal and maternal alleles can be determined. ... hit" occurs in the normal copy of the MEN1 gene. This somatic mutation may be a point mutation, a microdeletion, or loss of a chromosomal fragment (detected as loss of heterozygosity, LOH). Within ... one can assess transmission of the different MEN1 alleles and compare this pattern to development of the disorder to determine which allele is associated with risk of MEN-1. In the pedigree shown,...
Ngày tải lên: 07/07/2014, 01:20
Chapter 081. Principles of Cancer Treatment (Part 4) pdf
... Chapter 081. Principles of Cancer Treatment (Part 4) Palliation Surgery is employed in a number of ways for supportive care: insertion of central venous catheters, control of pleural and ... for recurrent pulmonary emboli, stabilization of cancer- weakened weight-bearing bones, and control of hemorrhage, among others. Surgical bypass of gastrointestinal, urinary tract, or biliary ... (Fig. 81-2). Plotting the fraction of surviving cells against doses of x-rays or gamma radiation, the curve has a shoulder that reflects the cell's repair of sublethal damage, followed by...
Ngày tải lên: 07/07/2014, 01:20
Chapter 081. Principles of Cancer Treatment (Part 9) pdf
... endogenous regulators of the cell death pathway are activated (Fig. 81-3). Figure 81-3 Chapter 081. Principles of Cancer Treatment (Part 9) Following demonstration of activity in animal ... improve their use. A general view of how cancer treatments work is that the interaction of a chemotherapeutic drug with its target induces a "cascade" of further signaling steps. These ... mediate cell death signals. Modulation of apoptosis by manipulation of signal transduction pathways has emerged as a basis for understanding the actions of drugs and designing new strategies...
Ngày tải lên: 07/07/2014, 01:20
Chapter 081. Principles of Cancer Treatment (Part 10) pdf
... function of these Chapter 081. Principles of Cancer Treatment (Part 10) Integration of cell death responses. Cell death through an apoptotic mechanism requires active participation of the ... not being in the appropriate phase of the cell cycle to allow drug lethality, or from decreased uptake, increased efflux, metabolism of the drug, or alteration of the target, e.g., by mutation ... important in regulating cellular proliferation and the behavior of tumor cells in vitro, in vivo it is unclear whether all of the actions of chemotherapeutic agents to cause cell death can be attributed...
Ngày tải lên: 07/07/2014, 01:20
Schaum’s Outline Series OF Principles of Computer Science phần 9 pdf
Ngày tải lên: 12/08/2014, 21:22
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