principles of clinical pharmacology second edition 2007
PRINCIPLES OF CLINICAL PHARMACOLOGY Second Edition potx
Ngày tải lên :
22/03/2014, 23:20
... effective use of
medicine can be traced back at least to Rudolph
Bucheim (1820–1879), who has been credited with
1
PRINCIPLES OF CLINICAL PHARMACOLOGY, SECOND EDITION
20 Principles of Clinical Pharmacology
Therefore, ... basic principles of clinical phar-
macology currently are being applied in the process of drug
development.
Journals
Clinical Pharmacology and Therapeutics
British Journal of Clinical Pharmacology
Journal ... level of
1.4 ng/mL when measured by the immunoassays
11
PRINCIPLES OF CLINICAL PHARMACOLOGY, SECOND EDITION
CHAPTER
3
Compartmental Analysis of Drug
Distribution
ARTHUR J. ATKINSON, JR.
Clinical...
- 568
- 1.1K
- 0
CRC Desk Reference of Clinical Pharmacology SECOND EDITION doc
Ngày tải lên :
06/03/2014, 14:20
... designation of Chester Fritz Distinguished
Professor of Pharmacology and of Clinical Neuroscience, the
highest honor bestowed by the University of North Dakota.
8 DESK REFERENCE OF CLINICAL PHARMACOLOGY
For ... July of 1999, he was appointed professor
and chairman of the Department of Pharmacology and Tox-
icology at the University of North Dakota School of Med-
icine and Health Sciences. In September of ... infringe.
Library of Congress Cataloging-in-Publication Data
Ebadi, Manuchair S.
Desk reference of clinical pharmacology / author, Manuchair Ebadi. 2nd ed.
p. ; cm.
Rev. ed. of: CRC desk reference of clinical...
- 822
- 425
- 0
TEXTBOOK of RECEPTOR PHARMACOLOGY Second Edition pot
Ngày tải lên :
06/03/2014, 14:20
... mechanisms of activation of dendritic cells, and the control
of microvascular circulation in human skin.
Torben Johansen, M.D., dr. med.,
is Docent of Pharmacology, Department of Physiology and
Pharmacology, ... Fellow of University College London in
1993 and received the degree of Doctor of Science from the University of London in the same
year. He was elected to the Fellowship of the Royal College of Physicians ... F.R.C.P.,
is Professor of Immunopharmacology
at University College London. He has also been a Visiting Professor at the University of Southern
Denmark, Odense, Denmark, and the University of Tasmania,...
- 302
- 374
- 0
physical principles of food preservation second edition revised and expanded food science and technology
Ngày tải lên :
02/04/2014, 15:05
... to the Second Edition
In the 28 years since the first edition of this textbook, significant advances have
been made in our understanding of physical chemistry of foods, and in particular
of the ... osmotic pressure, c is concentration of solute in gl
21
of solution
and M
2
is molecular weight of the solute.
One of the many uses of Eq. (89) was determination of molecular weight.
In that connection, ... the development and application of new processes for
preservation of foods. As predicted in the preface of the first edition, processes
today seek optimization of nutritional and quality factors...
- 639
- 680
- 2
Principles of Engineering Mechanics Second Edition pdf
Ngày tải lên :
27/06/2014, 05:20
... study of the motion of material
bodies and of the associated forces.
The study of motion is called kinematics and
involves the use of geometry and the concept of
time, whereas the study of the ... vector sum of the
external forces acting on a particular set of
particles equals the total mass times the
acceleration of the centre of mass, irrespective of
the individual motion of the separate ...
Kinetics
of
a particle in plane motion,
21
Introduction. Newton’s laws
of
motion. Units.
Types
of
force. Gravitation. Frames
of
reference.
Systems of particles. Centre of mass. Free-body...
- 275
- 756
- 1
Principles of Engineering Mechanics Second Edition H. R. Harrison potx
Ngày tải lên :
27/06/2014, 18:20
... vector sum of the
external forces acting on a particular set of
particles equals the total mass times the
acceleration of the centre of mass, irrespective of
the individual motion of the separate ... law
Every body continues
in
a state of rest
or
of
uniform rectilinear motion unless acted upon by a
force.
Second law
The rate of change of momentum of a body is
proportional to the force ... syllabuses
of
degree courses in
engineering. The emphasis of the book is on the
principles
of
mechanics and examples are drawn
from a wide range
of
engineering applications.
The order
of
presentation...
- 275
- 418
- 0
Principles of Engineering Mechanics Second Edition H. R. Harrison ppt
Ngày tải lên :
27/06/2014, 23:20
... basic principles
of
the
Part
1,
Part 2 and much
of
the Part
3
Engineering
Mechanics syllabuses
of
degree courses in
engineering. The emphasis of the book is on the
principles
of
mechanics ... law
Every body continues
in
a state of rest
or
of
uniform rectilinear motion unless acted upon by a
force.
Second law
The rate of change of momentum of a body is
proportional to the force ...
of
the
box
is
a,
determine
the
tension
T,.
L
Figure 3.13
W
=
W(-j)
=
-mu'
From Newton's second law (equation 3.1)
CF=ma
Principles
of
Engineering
Mechanics
Second...
- 275
- 675
- 0
Chapter 005. Principles of Clinical Pharmacology (Part 1) pps
Ngày tải lên :
06/07/2014, 08:20
... Chapter 005. Principles of Clinical
Pharmacology
(Part 1)
Harrison's Internal Medicine > Chapter 5. Principles of Clinical
Pharmacology
Principles of Clinical Pharmacology: Introduction ... accompaniment of drug
therapy, this is not the case. The goal of this chapter is to describe the principles of
clinical pharmacology that can be used for the safe and optimal use of available ... of the target molecule itself or of variability in the broad biologic context
in which the drug-target interaction occurs to achieve drug effects.
Two important goals of the discipline of clinical...
- 5
- 332
- 0
Chapter 005. Principles of Clinical Pharmacology (Part 2) ppt
Ngày tải lên :
06/07/2014, 08:20
... P-glycoprotein, the product of the
normal expression of the MDR1 gene. P-glycoprotein is expressed on the apical
aspect of the enterocyte and on the canalicular aspect of the hepatocyte (Fig. 5-3); ... from the site of administration (Fig. 5-
2). The extent of absorption may be reduced because a drug is incompletely
released from its dosage form, undergoes destruction at its site of administration, ...
a
Inhibitors affect the molecular pathway, and thus may affect substrate.
b
Clinically important genetics variants described.
A listing of CYP substrates, inhibitors, and inducers is maintained at
http://medicine.iupui.edu/flockhart/table.htm....
- 8
- 416
- 0
Chapter 005. Principles of Clinical Pharmacology (Part 3) docx
Ngày tải lên :
06/07/2014, 08:20
... intravenous infusion, plasma concentrations at steady
Chapter 005. Principles of Clinical
Pharmacology
(Part 3)
Clinical Implications of Altered Bioavailability
Some drugs undergo near-complete ... a typical intravenous dose of verapamil is 1–5 mg, compared
to the usual single oral dose of 40–120 mg. Administration of low-dose aspirin can
result in exposure of cyclooxygenase in platelets ... tissues, the volume of distribution can be far greater than
any physiologic space. For example, the volume of distribution of digoxin and
tricyclic antidepressants is hundreds of liters, obviously...
- 4
- 420
- 0
Chapter 005. Principles of Clinical Pharmacology (Part 4) ppsx
Ngày tải lên :
06/07/2014, 08:20
...
Chapter 005. Principles of Clinical
Pharmacology
(Part 4)
Clinical Implications of Drug Distribution
Digoxin accesses its cardiac site of action slowly, over a distribution phase
of several ... prevent elimination by
very rapid (t
1/2
of seconds) uptake into erythrocytes and endothelial cells before
the drug can reach its clinical site of action, the atrioventricular node.
Plasma ... volume of distribution of lidocaine is reduced. Therefore, lower-than-
normal loading regimens are required to achieve equivalent plasma drug
concentrations and to avoid toxicity.
Rate of Intravenous...
- 5
- 320
- 0
Chapter 005. Principles of Clinical Pharmacology (Part 5) doc
Ngày tải lên :
06/07/2014, 08:20
... effect of the drugs, it may produce
severe agonist–mediated effects (such as hypertension or tachycardia) if the
blocking drug is abruptly withdrawn.
Chapter 005. Principles of Clinical
Pharmacology ... site of action, it alters the function of that
molecular target, with the ultimate result of a drug effect that the patient or
physician can perceive. For drugs used in the urgent treatment of ... accumulation of
active metabolites. Commonly, the clinical effect develops as a downstream
consequence of the initial molecular effect the drug produces. Thus, administration
of a proton-pump...
- 6
- 357
- 0
Chapter 005. Principles of Clinical Pharmacology (Part 6) pdf
Ngày tải lên :
06/07/2014, 08:20
... Response
Chapter 005. Principles of Clinical
Pharmacology
(Part 6)
Principles of Dose Selection
The desired goal of therapy with any drug is to maximize the likelihood of
a beneficial effect ... an understanding of the relationships
between plasma concentration and anticipated effects. For example, measurement
of QT interval is used during treatment with sotalol or dofetilide to avoid ... concentration and
beneficial or adverse drug effect, measurement of plasma levels can provide a
valuable tool to guide selection of an optimal dose. This is particularly true when
there is a...
- 4
- 379
- 1
Tìm thêm:
- hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam
- xác định các mục tiêu của chương trình
- xác định các nguyên tắc biên soạn
- khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn
- khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản
- khảo sát chương trình đào tạo gắn với các giáo trình cụ thể
- xác định thời lượng học về mặt lí thuyết và thực tế
- tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam
- điều tra đối với đối tượng giảng viên và đối tượng quản lí
- điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1
- khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam
- khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu
- nội dung cụ thể cho từng kĩ năng ở từng cấp độ
- xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct
- phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ
- mở máy động cơ lồng sóc
- mở máy động cơ rôto dây quấn
- các đặc tính của động cơ điện không đồng bộ
- hệ số công suất cosp fi p2
- đặc tuyến hiệu suất h fi p2