primary cns b cell lymphoma

... relation to lymphoma Cancer 1983, 51:476-486 Kulow BF, Cualing H, Steele P, VanHorn J, Breneman JC, Mutasim DF, Breneman DL: Progression of cutaneous B- cell pseudolymphoma to cutaneous B- cell lymphoma ... hepatitis B virus surface antigen (HBsAg), hepatitis B virus core antibody (HBcAb) and hepatitis C virus (HCV) antibody Also, tumor markers including carcinoembryonic antigen and carbohydrate ... A, Black C, Min AD, Strauchen J, Thung SN: Primary < /b> hepatic marginal zone B- cell lymphoma of mucosa-associated lymphoid tissue type in a patient with primary < /b> biliary cirrhosis Arch Pathol Lab Med...

Ngày tải lên: 09/08/2014, 01:24

... PF, Baehrel B: Primary < /b> cardiac lymphoma: Diagnosis and treatment Arch Mal Coeur Vaiss 2005, 98:875-880 Sutcliffe SB, Gospodarowicz MK: Primary < /b> extranodal lymphomas In The Lymphomas Edited by: ... atrioventricular block revealing a primary < /b> cardiac nonHodgkin large B- cell lymphoma of the right ventricle: a case report Journal of Medical Case Reports 2011 5:433 Submit your next manuscript to BioMed ... competing interests Received: March 2011 Accepted: September 2011 Published: September 2011 References Mikdame M, Ennebi K, Bahrouch L, Benyass A, Dreyfus F, Touloune F: Localisations cardiaques...

Ngày tải lên: 10/08/2014, 23:20

... associated with B- cell lymphoproliferative disorders such as diffuse large B- cell lymphoma, myeloma, lymphoplasmacytic lymphoma, marginal zone lymphoma and even non-neoplastic plasma cell proliferation ... Dutcher bodies and give the strongest clue for the diagnosis The Ig inclusions may be found in a range of B- cell neoplasms, including chronic lymphocytic leukemia, marginal zone B- cell lymphoma ... immunoglobulin in B- cell lymphomas Virchows Arch B Cell Pathol Incl Mol Pathol 1986, 52:207-220 Guglielmi P, Preud’Homme JL, Gourdin MF, Reyes F, Daniel MT: Unusual intracytoplasmic immunoglobulin...

Ngày tải lên: 11/08/2014, 00:22

... intravascular lymphomatosis: an updated review of malignant histiocytosis-like B- cell lymphoma Leuk Lymphoma 1999, 33(5-6):459-73, Review Erratum in: Leuk Lymphoma 1999 Jun;34(1-2):following 206 Table Brief ... R-CHOP: rituximab-cyclophosphamide, doxorubicin, vincristine, and prednisone R-THP-COP: rituximab-pirarubicin, cyclophosphamide, vincristine and prednisolone PBSC: peripheral blood stem cell transplantation ... summary of intravscular large B- cell lymphoma Number of cases Source Publication Country B- IVL/ total (%) Age (y) Sex Symptoms range (M/ neurological cuteneous Blymphadenopathy hepatomegaly splenomegaly...

Ngày tải lên: 10/08/2014, 21:23

... large B- cell lymphoma in British Columbia J Clin Oncol 2005, 23(22):5027-33 Calo’ V, Migliavacca M, Bazan V, Macaluso M, Buscemi M, Gebbia N, Russo A: STAT proteins: from normal control of cellular ... Varin-Blank N, Ajchenbaum-Cymbalista F, Ledoux D: Constitutive and B- cell receptor-induced activation of STAT3 are important signaling pathways targeted by bortezomib in leukemic mantle cell lymphoma ... polyclonal antibody, Santa Cruz Biotechnology) for STAT3, anti-P-STAT3 antibody (9145, rabbit monoclonal antibody, Cell Signaling Technology) for P-STAT3Tyr705, and antibodies for BCL6, CD10, MUM1...

Ngày tải lên: 10/08/2014, 21:23

... has also been found expressed in B- cell lymphomas such as DLBCL and FL [25] The clinical impact of aberrant T -cell or NK -cell markers in B- cell lymphoproliferative disorders is unknown but deserves ... diagnosis of ALK-DLBCL should include lymphoblastic lymphoma, anaplastic variants of DLBCL, plasmablastic lymphoma (PBL), primary < /b> effusion lymphoma (PEL), solid variants of PEL and plasmablastic myeloma ... large B- cell lymphoma with extensive bone marrow involvement] Korean J Lab Med 2008, 28(2):89-94 De Paepe P, Baens M, van Krieken H, Verhasselt B, Stul M, Simons A, Poppe B, Laureys G, Brons...

Ngày tải lên: 10/08/2014, 22:20

... 0.6266 DLBCL 0.1507 0.6353 0.7852 AIDS -DLBCL 0.228 0.6266 0.7852 B Figure than lymphoma (PL) is more similar to diffuse large B- cell lymphoma (DLBCL) and AIDS-related DLBCL (AIDSDLBCL)1 Plasmablastic ... Plasmablastic plasma cell myeloma (PCM) Plasmablastic lymphoma (PL) is more similar to diffuse large B- cell lymphoma (DLBCL) and AIDS-related DLBCL (AIDS-DLBCL) than plasma cell myeloma (PCM) A ... characterized by Delecluse et al [1] They proposed that this constituted a new subtype of diffuse large B cell lymphoma (DLBCL); it was suggested as a distinct entity based on its blastic morphology,...

Ngày tải lên: 10/08/2014, 22:20

... DLBCL population List of abbreviations BM: bone marrow; CT: computed tomography; DLBCL: diffuse large B- cell lymphoma; ECOG: eastern cooperative oncology group; FISH: fluorescent in-situ hybridisation; ... of peripheral blood and bone marrow in the staging of B- cell malignant lymphoma Blood 1999, 94(11):3889-96 Chadburn A, Knowles DM: Paraffin-resistant antigens detectable by antibodies L26 and ... trephine biopsies This has been demonstrated in previous studies [35] and largely attributed to sampling and the tendency of lymphoma cells to adhere to bony trabeculae [36] As such, there would be...

Ngày tải lên: 10/08/2014, 22:20

... Br J Surg 1993, 80:1101-1106 Raderer M, de Boer JP: Role of chemotherapy in gastric MALT lymphoma, diffuse large B- cell lymphoma and other lymphomas, Best Practice & Research Clinical Gastroenterology ... 24:19-26 Ferreri Andrés JM: Carlos Montalbán Primary < /b> diffuse large B- cell lymphoma of the stomachCritical Reviews in Oncology/Hematology 2007, 63(1):65-71 Aleman BMP, Haas Rick LM, van der Maazen Richard ... therapy of gastric lymphoma Cancer 1986, 58:1389-99 11 Cogliatti SB, Schmid U, Schumacher U, Eckert F, Hansmann M, Hedderich J, Takahashi H, Lennert K: Primary < /b> B- cell gastric lymphoma: a clinicopathological...

Ngày tải lên: 10/08/2014, 22:21

... with TCR Vb13-specific antibody and imaged by LSM (×630) A) CD3+T cells transduced with Vb13-IRES-TCR Va6 recombinant plasmid and stained by FITC-TCR Vb13specific antibody B) CD3+T cells transferred ... TCR Vb subfamily T cells were identified in the PB of patients with DLBCL, which was presumed to have been driven by the stimulation of epitopes in DLBCL [22] The fulllength TCRVa6- and Vb13-chain ... cell lymphomas cell line, expressed DLBCL-associated antigen), Molt-4 cells (human acute lymphoblastic leukemia cell line), Raji cells (human Burkitt lymphoma cell line), all from ATCC, were cultured...

Ngày tải lên: 10/08/2014, 22:21

... Abbreviations ABC: avidin-biotin complex; ABC-DLBCL: activated B- cell- like DLBCL; Bcl: B- cell lymphoma; BL: Burkitt lymphoma; CD: cluster designation marker; cHL: classical Hodgkin’s lymphoma; CK: ... peripheral blood B- cells (ABC-DLBCL) Patients with GCBDLCBL had significantly better overall survival than those with ABC-DLBCL [18,19] The patients with GCB-DLCBL had better prognosis than the non-GCB ... sub-classify DLBCL into the germinal center B- cell- like DLBCL (GCB-DLBCL) and activated B- cell- like DLBCL (ABCDLBCL) sub-groups, with comparable differences in clinical behavior [16] Alizadeh et al [17]...

Ngày tải lên: 11/08/2014, 00:23

... Apaf-1 APS dATP/ATP 5-Aza Bak Bax Bcl-2 BH Bid tBid BIR BL BPB CARD caspase CB ced CHAPS CTB Cyt c Dark DED DEVD-AMC DIABLO DISC DMRIE-C DMSO DNA DRs DREDD DTT E2 E3 EBV EBNA mitochondria transmemrane ... 2'deoxycytidine BCL2-antagonist/killer Bcl-2-associated X protein B- cell lymphoma protein Bcl-2 homology BH3 interacting domain death agonist truncated Bid baculoviral-IAP-repeat Burkitt’s lymphoma bromphenol ... Singapore i TABLE OF CONTENTS Acknowledgements i Table of Contents ii Summery vi List of Tables vii List of Figures viii Abbreviations xi List of Publications xiv PART I INTRODUCTION 1 B CELL LYMPHOMA...

Ngày tải lên: 12/09/2015, 10:17

... with pSS Association between BAFF -871 T/C polymorphism and serum BAFF level in 95 patients with pSS Bars represent mean serum BAFF levels BAFF = B- cell- activating factor; pSS, primary < /b> Sjögren's ... with pSS Association between BAFF -871 T/C polymorphism and serum BAFF level in 95 patients with pSS The bar represents the standard error BAFF = B- cell- activating factor; pSS, primary < /b> Sjögren's ... did not influence BAFF level Surprisingly, no correlation was observed between BAFF polymorphism and BAFF mRNA levels in patients with pSS The absence of concordance between BAFF protein and mRNA...

Ngày tải lên: 09/08/2014, 07:20

... autoantigens but can also concomitantly activate B cells by the local secretion of BAFF BAFF overexpression might have a pathogenic role in lymphomas, because increased BAFF expression was observed ... investigated whether soluble forms of BAFF could be secreted by epithelial cells At baseline and after stimulation with IL-10 and with TNF-α, ELISA detected no soluble BAFF in cells from patients ... the combination of apoptotic bodies from epithelial cells and anti-SSA antibodies could induce IFN-α production by infiltrating cells, which could then induce BAFF expression by epithelial cells...

Ngày tải lên: 09/08/2014, 07:20

... and p53; in the patient with Burkitt-like lymphoma, malignant cells expressed bcl-6 and p53; in the with Burkitt-like lymphoma, malignant cells expressed bcl-6 and not bcl-2; in two patients there ... H, Kaneko E, Kobayashi H: Regression of primary < /b> gastric diffuse large B- cell lymphoma after eradication of Helicobacter pylori Gastrointest Endosc 2001, 54:643-645 Alpen B, Robbecke J, Wundisch ... cases of primary < /b> gastric large B- cell lymphoma that responded to antibiotic therapy had been described and, more recently, Chen et al [7] reported in a prospective study the disappearance of primary...

Ngày tải lên: 09/08/2014, 07:21

... SQ, Hood B, Barker J, Benveniste RJ: Primary < /b> CNS < /b> Lymphoma mimicking pituitary apoplexy: case report Pituitary 2009, 12(1):76-79 Ogilvie CM, Payne S, Evanson J, Lister TA, Grossman A: Lymphoma ... C D B BEFORE AFTER Figure PET scan imaging before and after six cycles of R-CHOP (A) PET scan before chemotherapy Note multiple metabolically active areas in the liver, axillae, neck and base ... Table 1) Discussion We describe a patient with diffuse large B- cell lymphoma metastasizing to the anterior pituitary, in whom pituitary function was restored after successful treatment of the lymphoma...

Ngày tải lên: 10/08/2014, 23:20

... hormone-related protein produced by B- cell type primary < /b> malignant lymphoma of the kidney Ann Hematol 1998, 76:221-224 Amezyane T, Lecoules S, Bordier L, Blade JS, Desrame J, Bechade D, Coutant G, Algayres ... the bioactivity of the tumor extract producing C-AMP in osteoblasts Since that time, a limited number of patients with hypercalcemic B- cell NHL secondary to PTHrP have been reported [6,8-15] Table ... anorexia resumed A bone marrow biopsy was performed and there was no bone marrow involvement Based on the lack of lytic bone lesions, no bone marrow involvement, no plasmacytosis in her bone marrow,...

Ngày tải lên: 11/08/2014, 02:21

... cells [24] In DT40 cells, BCR signaling is transduced from BCR and membrane-proximal factors (Syk, BTK, BLNK and PLCc2, etc), via mainly PKCd, PKCe and PKCf, to NF-jBs (probably c-Rel and NFp50) ... auto-immune diseases and B- cell lymphomas Fine control of pre-mature B- cell apoptosis by E2A Immunoblotting Cells were treated with 10% trichroloacetic acid, collected by centrifugation 20 000 ... apoptotic cell death in E2A)/) is suppressed by collaboration of both BCR signaling and E2A depletion, mainly via moderate changes in amounts of the inhibitors survivin, IAP2 and ICAD (and probably...

Ngày tải lên: 16/03/2014, 04:20

... other neoplastic B- cells [62,63] For this reason CLL is nowadays believed to derive from subsets of marginal zone memory B- cells that have undergone either a T -cell dependent or Tcell independent ... replicative features of the B- CLL subgroups defined by immunoglobulin V gene mutations Blood 2004, 103:375-382 Grabowski P, Hultdin M, Karlsson K, Tobin G, Aleskog A, Thunberg U, Laurell A, Sundstrom ... Deaglio S, Capobianco A, Bergui L, Durig J, Morabito F, Duhrsen U, Malavasi F: CD38 is a signaling molecule in B- cell chronic lymphocytic leukemia cells Blood 2003, 102:2146-2155 Foster AE, Brenner...

Ngày tải lên: 18/06/2014, 15:20

... (Figure 5, grey bars) but with over 70% of the implants presenting BV1, BV2, BV4, BV5S2, BV8S3, BV10 and BV15 clonotypes Interestingly, BV1 and BV8 clonotypes were decreased by cyclophosphamide ... component is also promoted by B cell reconstitution Interestingly, BV1, BV8 and BV11 T cell expansions were greatly reduced or lost, while a new set of BV4, BV5S2, BV9 and BV16-20 expansions arose, ... mice reconstituted with B cells (white bars), and diabetic NOD.Igμnull mice reconstituted with B cells (grey bars) subsets of T cells, in comparison to age-matched B- cell reconstituted NOD.Igμ...

Ngày tải lên: 18/06/2014, 19:20