... California, Irvine, College of Medicine, CA, USA AAbbssttrraa c ctt Chronic hepatitis B (CHB) is one of the important public health problems worldwide. Major advances have been ... Director of Hepatology Services and Associate Professor of Clinical Medicine, Divisions of Gastroenterology and Transplantation, University of California, Irvine, California, USA. His current ... Irvine, California, USA. His current researches include natural history and management of hepatitis B and C and chemoprevention of hepatocellular carcinoma. C Coorrrreessppoonnddiinngg...
... permission. Copyright 2002 American College of Chest Physicians. The presence of COPD greatly increases the total cost of care for patients, especially when inpatient costs are considered. ... underrecognition and underdiagnosis of COPD still affect the accuracy of mortality data. Although COPD is often a primary cause of death, it is more likely to be listed as a contributory cause of ... present in patients with COPD. Chronic bronchitis, or the presence of cough and sputum production for at least 3 months in each of two consecutive years, remains a clinically and mortality...
... framework 15 2. Competency profiles of therapeutically educated patients 17 Competencies of type 1 diabetic patients 17 Competencies of type 2 diabetic patients 20 Competencies of asthma patients ... significance of the subject. Two levels of training in therapeutic patient education* are in use: basic and postbasic. Basic training concerns the practice of therapeutic patient educa-tion*. ... therapeutic effects (clinical, biological, psychological, educational, social, economic) and make the indicated adjustments 15. periodically evaluate and improve the educational performance* of...
... assess the clinical profiles ofchronichepatitisC (CHC) at first presentation and clinical implication of dynamic follow-up of ALT level in a county medical center setting. A total of 294 patients ... with chronic HCV infection, a series of epidemiological, clinical and biochemical variables were collected at entry through a retrospective chart review. The clinical variables collected included ... that more than 80% of the HCV infections become chronic, which may progress to cirrhosis and complicated by hepatic decompensation and hepatocellular carcinoma (HCC) [2-4]. HCV-related end-stage...
... 5’ cct agg tca cag tga cgt gg 3’5’ ggt gag cac tac ctg act agc 3’5’ tca ttc tat gtg ctg gag atg g 3’5’ tgg ggg aag tgg gta aga gt 3’5’ ctc gct gca acccaa ctg gc 3’5’ ctc gct gca acccaa ctg ... response ofchronichepatitis B to IFN-a therapy.Introduction Hepatitis B is a worldwide disease and remains a signifi-cant etiology ofchronic hepatitis, cirrhosis and hepato-cellular carcinoma, ... immunoregula-tory cytokines such as IFN-gand TNF-a inhibit HBVreplication through the noncytolytic process[20]. In con-trast, IL-10 counteracts their effector mechanisms[8,10,11,17]. Because the capacity...
... re-mains unclear (4), particularly in HBeAg-negative CHB patients. In contrast, a large body of evidence showed the incidence of hepatic steatosis in chronic hepatitis C (CHC) patients ranged from ... compared the clinical and histological features of HBeAg-negative CHB patients with or without hepatic steatosis, so as to evaluate the predictors of clinical and pathological characteristics in ... 5′-TGTCTCGTGTTACAGGCGGGGT-3', asymmetric primer 2 was 5′-GAGGCATAGCAGCAGGA GAAGAG-3', and fluorescent primer was 5′-TCGCTGGAAGTGTCTGCGGCGT-3'. Serum assays Fasting blood was collected...
... adolescent vaccinatin programmes in Italy. Vaccine 2000;18:S31-S34. 77. Chang MH, Chen CJ,cLai MS. Universal hepatitis B vaccination in Taiwan and the incidence of hepatocellular carcinoma in children. ... that occult hepatitis B might affect responsiveness ofchronichepatitisC to interferon therapy and disease progress. 6. HBeAg-negative CHB HBeAg-negative chronichepatitis B (e-CHB), characterized ... genotype C in China [34]. Accumulated data suggest the importance of genotype, subgroup and recombination that may influence the biological characteristics of virus and clinical outcome of HBV infection....
... smoking and excessive alcohol consumption, include reduced levels of physical activity. Of particular concern is the increasingly unhealthy diet and physical inactivity of adolescents and children. ... the PreventionofChronic Diseases, op. cit. 39 Weight control and physical activity. Lyon, International Agency for Research on Cancer, 2002 (IARC Handbooks of Cancer Prevention, Vol. 6); ... development of environments that are conducive to physical activity? V.7. Socio-economic inequalities V.7.1. Food choice is determined by both individual preferences and socio-economic factors29....
... 7 3 5Calcimimetics 1 5 0Other bone treatments c 41 3Ca, calcium; CKD, chronic kidney disease; PTH, parathyroid hormone; SERM, Selective Estrogen Receptor Modulators.aExcludes articles in ... thatindividual values of serum calcium and phosphorus,evaluated together, be used to guide clinical practicerather than the mathematical construct of calcium–-phosphorus product (Ca  P) (2D).3.1.6. ... of CKD–MBD: vascular calcification3.3.1. In patients with CKD stages 3–5D, we suggest that alateral abdominal radiograph can be used to detect thepresence or absence of vascular calcification,...
... Treatment ofchronichepatitis B: fromresearch to clinical practice via the consensus conferences.Curr Pharm Des 2004, 10(17):2063-2075.30. Cotonat T, Quiroga JA, Lopez-Alcorocho JM, Clouet R, ... DNA copies. A comparison with HBV DNA copies demonstratedthat the overall accuracy of the HBpreSAg test could reach 72% for active HBV replication.HBpreSAg changes were well correlated with changes ... patientswith chronichepatitis B infection: The effect on hepatitis B eantigen seroconversion and the development of cirrhosis-related complications. Hepatology 2001, 34(1):139-145.33. Craxi A, Cooksley...
... uncomplicated group.Clinical characteristics and co-morbid chronic illnessTable 2 describes the clinical characteristics and co-mor-bid chronic illnesses of CHB patients. The mean duration of CHB illness ... associ-ated with all HRQOL scores, except the SF-36v2 PCSscore. The effect of the total number ofchronic disease orother specific chronic diseases did not reach statistical sig-nificance ... regression on HRQOL scores*SF-6D SF36v2-PCS SF36v2-MCS CLDQ-OverallCoefficient (95% CI) Coefficient (95% CI) Coefficient (95% CI) Coefficient (95% CI)Stage of illness (vs. uncomplicated CHB)Impaired...
... hepatitis C. Stratification wasachieved in blocks of six within each variable, such that ineach block of six half of the clients would receive SEC andhalf of the clients EPC. This method of stratified ... of their effectiveness and cost-effectiveness in pragmatic clin-ical trials.ConclusionWe were not able to prove the efficacy of EPC in compar-ison with SEC in the preventionofhepatitisC in IDUs.Notwithstanding ... Behaviour Scale did not accountfor differences on any of the outcome measures.DiscussionWe were not able to demonstrate the efficacy of EPC com-pared to SEC in the preventionofhepatitisC amongstinjecting...
... Impact of increased legal access to needles and syringeson practices of injecting-drug users and police officers-Con- Harm Reduction Journal 2006, 3:27 http://www.harmreductionjournal.com/content/3/1/27Page ... lack of political will, therecently published UK Department of Health Hepatitis C Action Plan provides a window of opportunity to focuspolitical, research and clinical resources upon the com-mon ... conclusionReducing the incidence of HCV continues to present aconsiderable challenge. Recent UK based research con-ducted amongst injecting drug users documented an inci-dence rate of 41.8 per 100...